메뉴 건너뛰기




Volumn 965, Issue , 2002, Pages 274-280

Calpain upregulation and neuron death in spinal cord of MPTP-induced parkinsonism in mice

Author keywords

Apoptosis; Astrocyte; Dopaminergic neurons; Motor neuron; Substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2,3 DIHYDRO 1 METHYL 4 PHENYLPYRIDINIUM; CALPAIN;

EID: 0036291490     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04169.x     Document Type: Conference Paper
Times cited : (31)

References (43)
  • 3
    • 0023231751 scopus 로고
    • Geography, drinking water chemistry, pesticides and herbicides and the etiology of Parkinson's disease
    • (1987) Can. J. Neurol. Sci. , vol.14 , pp. 414-418
    • Rajput, A.H.1
  • 4
    • 0031576074 scopus 로고    scopus 로고
    • Familial Parkinson's diseases. The awakening of alpha-synuclein [news]
    • (1997) Nature , vol.388 , pp. 232
    • Goedert, M.1
  • 6
    • 0033525009 scopus 로고    scopus 로고
    • Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydroxylase gene in familial Parkinson's disease
    • (1999) Neuroreport , vol.10 , pp. 427-429
    • Lincoln, S.1
  • 7
    • 0032865590 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry
    • (1999) Brain , vol.122 , pp. 1421-1436
    • Damier, P.1
  • 8
    • 0032816549 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
    • (1999) Brain , vol.122 , pp. 1437-1448
    • Damier, P.1
  • 9
    • 0023635340 scopus 로고
    • Motor neuron disease, parkinsonism and dementia. Report of a case with diffuse Lewy body-like intracytoplasmic inclusions
    • (1987) Acta Neuropathol. , vol.75 , pp. 104-108
    • Delisle, M.B.1
  • 11
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice
    • (1984) Science , vol.224 , pp. 1451-1453
    • Heikkila, R.E.1
  • 12
    • 0021224694 scopus 로고
    • Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
    • (1984) Nature , vol.311 , pp. 467-469
    • Heikkila, R.E.1
  • 13
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4546-4550
    • Burns, R.S.1
  • 16
    • 0009589886 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • (1985) Life Sci. , vol.36 , pp. 2505-2508
    • Niklas, W.J.1
  • 18
    • 0030888286 scopus 로고    scopus 로고
    • In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
    • (1997) Neuroscience , vol.77 , pp. 1037-1048
    • Tatton, N.A.1    Kish, S.J.2
  • 19
    • 0024390719 scopus 로고
    • Mitochondrial complex 1 deficiency in Parkinson's disease
    • (1989) Lancet , vol.1 , pp. 1269
    • Schapira, A.H.1
  • 20
    • 0025242960 scopus 로고
    • Oxidation reactions in Parkinson's disease
    • (1990) Neurology , vol.40 , Issue.SUPPL. , pp. 32-37
    • Olanow, C.W.1
  • 21
  • 22
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency?
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1
  • 23
    • 12944250987 scopus 로고    scopus 로고
    • Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2875-2780
    • Hartmann, A.1
  • 24
    • 0035297146 scopus 로고    scopus 로고
    • Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice
    • (2001) Move. Disord. , vol.16 , pp. 185-189
    • Turmel, H.1
  • 26
    • 0022350722 scopus 로고
    • Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus
    • (1985) Neurosci. Lett. , vol.61 , pp. 195-200
    • Mitchell, I.J.1
  • 27
    • 0025074518 scopus 로고
    • Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP
    • (1990) Brain Res. , vol.527 , pp. 7-20
    • Seniuk, N.A.1
  • 28
    • 0025771595 scopus 로고
    • Catecholaminergic neurons in the parabrachial nucleus of normal individuals and patients with idiopathic Parkinson's disease
    • (1991) Ann. Neurol. , vol.30 , pp. 192-196
    • Goto, S.1    Hirano, A.2
  • 29
    • 0022476014 scopus 로고
    • Degeneration of noradrenergic and serotonergic but not dopaminergic neurones in the lumbar spinal cord of parkinsonian patients
    • (1986) Brain Res. , vol.380 , pp. 181-185
    • Scatton, B.1
  • 31
    • 0025856350 scopus 로고
    • Spinal cord inhibitory mechanisms in Parkinson's disease
    • (1991) Neurology , vol.41 , pp. 553-556
    • Lelli, S.1
  • 34
    • 0029882525 scopus 로고    scopus 로고
    • Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: A role in nerve cell death?
    • (1996) Neuroscience , vol.73 , pp. 979-987
    • Mouatt-Prigent, A.1
  • 35
    • 0033711406 scopus 로고    scopus 로고
    • Calpain upregulation in spinal cords of mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease
    • Neurological Mechanisms of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines. S.F. Ali, Ed.
    • (2000) Ann. N.Y. Acad. Sci. , vol.914 , pp. 275-283
    • Ray, S.K.1
  • 36
    • 0033919019 scopus 로고    scopus 로고
    • Combined TUNEL and double immunofluorescence labeling for detecting apoptotic mononuclear phagocytes in autoimmune demyelinating disease
    • (2000) Brain Res. Protocol. , vol.5 , pp. 305-311
    • Ray, S.K.1
  • 39
    • 0023658410 scopus 로고
    • Calcium-activated neutral protease and its endogenous inhibitor. Activation at the cell membrane and biological function
    • (1987) FEBS Lett. , vol.220 , pp. 271-277
    • Suzuki, K.1
  • 40
    • 0033594745 scopus 로고    scopus 로고
    • Diverse stimuli induce calpain overexpression and apoptosis in C6 glioma cells
    • (1999) Brain Res. , vol.829 , pp. 18-27
    • Ray, S.K.1
  • 41
    • 0033621607 scopus 로고    scopus 로고
    • 2+ influx upregulate calpain and induce apoptosis in PC12 cells
    • (2000) Brain Res. , vol.852 , pp. 326-334
    • Ray, S.K.1
  • 43
    • 0003002907 scopus 로고    scopus 로고
    • Deficit in a Krebs cycle mitochondrial enzyme in brains from patients with Parkinson's disease
    • 132(BP02-18)
    • (2001) J. Neurochem. , vol.78 , Issue.SUPPL.
    • Gibson, G.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.