hMTH1 depletion promotes oxidative-stress-induced apoptosis through a Noxa- and caspase-3/7-mediated signaling pathway

DNA Repair

Volumn 7, Issue 11, 2008, Pages 1809-1823

  Youn, Cha Kyung ^a,b   Jun, Jae Yeoul ^a   Hyun, Jin Won ^c   Hwang, Gul ^a,b   Lee, Byoung Rai ^a   Chung, Myung Hee ^d   Chang, In Youb ^a,b   You, Ho Jin ^a,b  

^a Chosun University   (South Korea)

^b Chosun University College of Medicine   (South Korea)

^c Jeju National University School of Medicine   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

Apoptosis; Caspase 3 7; Caspase 8; hMTH1; Hydrogen peroxide; Noxa; p53

Indexed keywords

CASPASE 3; CASPASE 7; CELL PROTEIN; HISTONE H2AX; MUTT HOMOLOG 1; PROTEIN NOXA; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; COMET ASSAY; DNA REPAIR ENZYMES; HUMANS; HYDROGEN PEROXIDE; MODELS, BIOLOGICAL; OXIDATIVE STRESS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 53149144632     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2008.07.010     Document Type: Article

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