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Volumn 213, Issue 9-10, 2008, Pages 759-765

Recent advances in the genetic analysis of PTEN and PI3K innate immune properties

Author keywords

Innate immunity; PI3K; PTEN; TLR

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TOLL LIKE RECEPTOR;

EID: 52749098868     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.07.028     Document Type: Review
Times cited : (38)

References (37)
  • 1
    • 22544445221 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of toll-like receptor 3 and 4
    • Aksoy E., Vanden B.W., Detienne S., Amraoui Z., Fitzgerald K.A., Haegeman G., Goldman M., and Willems F. Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of toll-like receptor 3 and 4. Eur. J. Immunol. 35 (2005) 2200-2209
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2200-2209
    • Aksoy, E.1    Vanden, B.W.2    Detienne, S.3    Amraoui, Z.4    Fitzgerald, K.A.5    Haegeman, G.6    Goldman, M.7    Willems, F.8
  • 3
    • 0033563141 scopus 로고    scopus 로고
    • Negative regulation by phosphatidylinositol 3-kinase of inducible nitric oxide synthase expression in macrophages
    • Az-Guerra M.J., Castrillo A., Martin-Sanz P., and Bosca L. Negative regulation by phosphatidylinositol 3-kinase of inducible nitric oxide synthase expression in macrophages. J. Immunol. 162 (1999) 6184-6190
    • (1999) J. Immunol. , vol.162 , pp. 6184-6190
    • Az-Guerra, M.J.1    Castrillo, A.2    Martin-Sanz, P.3    Bosca, L.4
  • 5
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering B.M., and Coffer P.J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376 (1995) 599-602
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 6
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley L.C. The phosphoinositide 3-kinase pathway. Science 296 (2002) 1655-1657
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 7
    • 1842424697 scopus 로고    scopus 로고
    • The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports toll-like receptor 4 signaling in murine peritoneal macrophages
    • Cao X., Wei G., Fang H., Guo J., Weinstein M., Marsh C.B., Ostrowski M.C., and Tridandapani S. The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports toll-like receptor 4 signaling in murine peritoneal macrophages. J. Immunol. 172 (2004) 4851-4857
    • (2004) J. Immunol. , vol.172 , pp. 4851-4857
    • Cao, X.1    Wei, G.2    Fang, H.3    Guo, J.4    Weinstein, M.5    Marsh, C.B.6    Ostrowski, M.C.7    Tridandapani, S.8
  • 8
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S., and Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359 (2001) 1-16
    • (2001) Biochem. J. , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 10
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • Fukao T., and Koyasu S. PI3K and negative regulation of TLR signaling. Trends Immunol. 24 (2003) 358-363
    • (2003) Trends Immunol. , vol.24 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 13
    • 34247577195 scopus 로고    scopus 로고
    • Vesicular stomatitis virus glycoprotein G activates a specific antiviral toll-like receptor 4-dependent pathway
    • Georgel P., Jiang Z., Kunz S., Janssen E., Mols J., Hoebe K., Bahram S., Oldstone M.B., and Beutler B. Vesicular stomatitis virus glycoprotein G activates a specific antiviral toll-like receptor 4-dependent pathway. Virology 362 (2007) 304-313
    • (2007) Virology , vol.362 , pp. 304-313
    • Georgel, P.1    Jiang, Z.2    Kunz, S.3    Janssen, E.4    Mols, J.5    Hoebe, K.6    Bahram, S.7    Oldstone, M.B.8    Beutler, B.9
  • 14
    • 33646705667 scopus 로고    scopus 로고
    • Regulation of the PTEN phosphatase
    • Gericke A., Munson M., and Ross A.H. Regulation of the PTEN phosphatase. Gene 374 (2006) 1-9
    • (2006) Gene , vol.374 , pp. 1-9
    • Gericke, A.1    Munson, M.2    Ross, A.H.3
  • 15
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • Guha M., and Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem. 277 (2002) 32124-32132
    • (2002) J. Biol. Chem. , vol.277 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 17
    • 19344365340 scopus 로고    scopus 로고
    • LY294002 inhibits LPS-induced NO production through a inhibition of NF-kappaB activation: independent mechanism of phosphatidylinositol 3-kinase
    • Kim Y.H., Choi K.H., Park J.W., and Kwon T.K. LY294002 inhibits LPS-induced NO production through a inhibition of NF-kappaB activation: independent mechanism of phosphatidylinositol 3-kinase. Immunol. Lett. 99 (2005) 45-50
    • (2005) Immunol. Lett. , vol.99 , pp. 45-50
    • Kim, Y.H.1    Choi, K.H.2    Park, J.W.3    Kwon, T.K.4
  • 19
    • 0034635221 scopus 로고    scopus 로고
    • Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
    • Li Z., Jiang H., Xie W., Zhang Z., Smrcka A.V., and Wu D. Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science 287 (2000) 1046-1049
    • (2000) Science , vol.287 , pp. 1046-1049
    • Li, Z.1    Jiang, H.2    Xie, W.3    Zhang, Z.4    Smrcka, A.V.5    Wu, D.6
  • 21
    • 44849113635 scopus 로고    scopus 로고
    • Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages
    • Luyendyk J.P., Schabbauer G.A., Tencati M., Holscher T., Pawlinski R., and Mackman N. Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J. Immunol. 180 (2008) 4218-4226
    • (2008) J. Immunol. , vol.180 , pp. 4218-4226
    • Luyendyk, J.P.1    Schabbauer, G.A.2    Tencati, M.3    Holscher, T.4    Pawlinski, R.5    Mackman, N.6
  • 23
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • Martin M., Rehani K., Jope R.S., and Michalek S.M. Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol. 6 (2005) 777-784
    • (2005) Nat. Immunol. , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3    Michalek, S.M.4
  • 24
    • 0037352702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is involved in toll-like receptor 4-mediated cytokine expression in mouse macrophages
    • Ojaniemi M., Glumoff V., Harju K., Liljeroos M., Vuori K., and Hallman M. Phosphatidylinositol 3-kinase is involved in toll-like receptor 4-mediated cytokine expression in mouse macrophages. Eur. J. Immunol. 33 (2003) 597-605
    • (2003) Eur. J. Immunol. , vol.33 , pp. 597-605
    • Ojaniemi, M.1    Glumoff, V.2    Harju, K.3    Liljeroos, M.4    Vuori, K.5    Hallman, M.6
  • 25
    • 33745868678 scopus 로고    scopus 로고
    • Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells
    • Rhee S.H., Kim H., Moyer M.P., and Pothoulakis C. Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells. J. Biol. Chem. 281 (2006) 18560-18568
    • (2006) J. Biol. Chem. , vol.281 , pp. 18560-18568
    • Rhee, S.H.1    Kim, H.2    Moyer, M.P.3    Pothoulakis, C.4
  • 28
    • 41849122634 scopus 로고    scopus 로고
    • TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages
    • Schabbauer G., Luyendyk J., Crozat K., Jiang Z., Mackman N., Bahram S., and Georgel P. TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. Mol. Immunol (2008)
    • (2008) Mol. Immunol
    • Schabbauer, G.1    Luyendyk, J.2    Crozat, K.3    Jiang, Z.4    Mackman, N.5    Bahram, S.6    Georgel, P.7
  • 29
    • 4143102310 scopus 로고    scopus 로고
    • LPS-induced upregulation of SHIP is essential for endotoxin tolerance
    • Sly L.M., Rauh M.J., Kalesnikoff J., Song C.H., and Krystal G. LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity 21 (2004) 227-239
    • (2004) Immunity , vol.21 , pp. 227-239
    • Sly, L.M.1    Rauh, M.J.2    Kalesnikoff, J.3    Song, C.H.4    Krystal, G.5
  • 30
    • 0001582482 scopus 로고
    • Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma
    • Staal S.P. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc. Natl. Acad. Sci. USA 84 (1987) 5034-5037
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 5034-5037
    • Staal, S.P.1
  • 32
    • 39049101676 scopus 로고    scopus 로고
    • Portrait of PTEN: messages from mutant mice
    • Suzuki A., Nakano T., Mak T.W., and Sasaki T. Portrait of PTEN: messages from mutant mice. Cancer Sci. 99 (2008) 209-213
    • (2008) Cancer Sci. , vol.99 , pp. 209-213
    • Suzuki, A.1    Nakano, T.2    Mak, T.W.3    Sasaki, T.4
  • 36
    • 33646471083 scopus 로고    scopus 로고
    • TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression
    • Yu Y., Nagai S., Wu H., Neish A.S., Koyasu S., and Gewirtz A.T. TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. J. Immunol. 176 (2006) 6194-6201
    • (2006) J. Immunol. , vol.176 , pp. 6194-6201
    • Yu, Y.1    Nagai, S.2    Wu, H.3    Neish, A.S.4    Koyasu, S.5    Gewirtz, A.T.6
  • 37
    • 34247220265 scopus 로고    scopus 로고
    • Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway
    • Zhang W.J., Wei H., Hagen T., and Frei B. Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proc. Natl. Acad. Sci. USA 104 (2007) 4077-4082
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4077-4082
    • Zhang, W.J.1    Wei, H.2    Hagen, T.3    Frei, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.