PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 24, Issue 10, 2004, Pages 1963-1969

  Schabbauer, Gernot ^a   Tencati, Michael ^a   Pedersen, Brian ^a   Pawlinski, Rafal ^a   Mackman, Nigel ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Blood coagulation; Endothelium; Fibrin; Inflammation; PI3 kinase; Thrombosis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIGEN; ANTITHROMBIN III; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBRIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; WORTMANNIN;

ANIMAL MODEL; ARTICLE; BLOOD CELL; BLOOD CLOTTING; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBRIN DEPOSITION; IMMUNE RESPONSE; INFLAMMATION; KIDNEY; LIVER; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BLOOD COAGULATION; CHEMOKINES; CHROMONES; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENDOTOXEMIA; HUMANS; INFLAMMATION; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; MACROPHAGE ACTIVATION; MICE; MICE, INBRED C57BL; MONOCYTES; MORPHOLINES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 5344249335     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000143096.15099.ce     Document Type: Article

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