메뉴 건너뛰기




Volumn 18, Issue 5, 2004, Pages 973-990

The relationship between the tumor physiologic microenvironment and angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACIDOSIS; ANGIOGENESIS; CARCINOGENESIS; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HYPOXIA; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; OXYGEN TRANSPORT; PARACRINE SIGNALING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SHEAR STRESS; TUMOR GROWTH; TUMOR VASCULARIZATION;

EID: 5044238255     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2004.06.006     Document Type: Review
Times cited : (15)

References (98)
  • 1
    • 84911539247 scopus 로고
    • The number and distribution of capillaries in muscle with calculation of the oxygen pressure head necessary for supplying the tissue
    • A. Krogh The number and distribution of capillaries in muscle with calculation of the oxygen pressure head necessary for supplying the tissue J Physiol London 52 1919 409 415
    • (1919) J Physiol London , vol.52 , pp. 409-415
    • Krogh, A.1
  • 2
    • 84944486367 scopus 로고
    • The supply of oxygen to the tissues and the regulation of the capillary circulation
    • A. Krogh The supply of oxygen to the tissues and the regulation of the capillary circulation J Physiol London 52 1919 457 474
    • (1919) J Physiol London , vol.52 , pp. 457-474
    • Krogh, A.1
  • 4
    • 0033000313 scopus 로고    scopus 로고
    • Quantification of longitudinal tissue pO2 gradients in window chamber tumours: Impact on tumour hypoxia
    • M.W. Dewhirst, E.T. Ong, R.D. Braun, B. Smith, B. Klitzman, and S.M. Evans Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia Br J Cancer 79 1999 1717 1722
    • (1999) Br J Cancer , vol.79 , pp. 1717-1722
    • Dewhirst, M.W.1    Ong, E.T.2    Braun, R.D.3    Smith, B.4    Klitzman, B.5    Evans, S.M.6
  • 5
    • 0030476061 scopus 로고    scopus 로고
    • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
    • H. Kimura, R.D. Braun, E.T. Ong, R. Hsu, T.W. Secomb, and D. Papahadjopoulos Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma Cancer Res 56 1996 5522 5528
    • (1996) Cancer Res , vol.56 , pp. 5522-5528
    • Kimura, H.1    Braun, R.D.2    Ong, E.T.3    Hsu, R.4    Secomb, T.W.5    Papahadjopoulos, D.6
  • 6
    • 0029948108 scopus 로고    scopus 로고
    • Arteriolar oxygenation in tumor and subcutaneous arterioles: Effects of inspired air oxygen content
    • M. Dewhirst, E. Ong, G. Rosner, S. Rehmus, S. Shan, and R. Braun Arteriolar oxygenation in tumor and subcutaneous arterioles: effects of inspired air oxygen content Br J Cancer 74 1996 S247 S251
    • (1996) Br J Cancer , vol.74
    • Dewhirst, M.1    Ong, E.2    Rosner, G.3    Rehmus, S.4    Shan, S.5    Braun, R.6
  • 9
    • 0032415845 scopus 로고    scopus 로고
    • Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels
    • T.W. Secomb, R. Hsu, R.D. Braun, J.R. Ross, J.F. Gross, and M.W. Dewhirst Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels Adv Exp Med Biol 454 1998 629 634
    • (1998) Adv Exp Med Biol , vol.454 , pp. 629-634
    • Secomb, T.W.1    Hsu, R.2    Braun, R.D.3    Ross, J.R.4    Gross, J.F.5    Dewhirst, M.W.6
  • 10
    • 0028241329 scopus 로고
    • Determination of local oxygen consumption rates in tumors
    • M. Dewhirst, T. Secomb, E. Ong, R. Hsu, and J. Gross Determination of local oxygen consumption rates in tumors Cancer Res 54 1994 3333 3336
    • (1994) Cancer Res , vol.54 , pp. 3333-3336
    • Dewhirst, M.1    Secomb, T.2    Ong, E.3    Hsu, R.4    Gross, J.5
  • 11
    • 0030614893 scopus 로고    scopus 로고
    • Interstitial pH and pO2 gradients in solid tumors in vivo: High resolution measurements reveal a lack of correlation
    • G. Helmlinger, F. Yuan, M. Dellian, and R. Jain Interstitial pH and pO2 gradients in solid tumors in vivo: high resolution measurements reveal a lack of correlation Nat Med 3 1997 177 182
    • (1997) Nat Med , vol.3 , pp. 177-182
    • Helmlinger, G.1    Yuan, F.2    Dellian, M.3    Jain, R.4
  • 12
    • 0026667152 scopus 로고
    • Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber
    • M.W. Dewhirst, E.T. Ong, B. Klitzman, T.W. Secomb, R.Z. Vinuya, and R. Dodge Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber Radiat Res 130 1992 171 182
    • (1992) Radiat Res , vol.130 , pp. 171-182
    • Dewhirst, M.W.1    Ong, E.T.2    Klitzman, B.3    Secomb, T.W.4    Vinuya, R.Z.5    Dodge, R.6
  • 13
    • 0027536635 scopus 로고
    • The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment
    • B.D. Kavanagh, B.E. Coffey, D. Needham, R.M. Hochmuth, and M.W. Dewhirst The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment Br J Cancer 67 1993 734 741
    • (1993) Br J Cancer , vol.67 , pp. 734-741
    • Kavanagh, B.D.1    Coffey, B.E.2    Needham, D.3    Hochmuth, R.M.4    Dewhirst, M.W.5
  • 15
    • 0032417673 scopus 로고    scopus 로고
    • Disturbed blood flow structuring as critical factor of hemorheological disorders in microcirculation
    • G. McHedlishvili Disturbed blood flow structuring as critical factor of hemorheological disorders in microcirculation Clin Hemorheol Microcirc 19 1998 315 325
    • (1998) Clin Hemorheol Microcirc , vol.19 , pp. 315-325
    • McHedlishvili, G.1
  • 16
    • 0028270939 scopus 로고
    • Fluctuations in microvascular blood flow parameters caused by hemodynamic mechanisms
    • M.F. Kiani, A.R. Pries, L.L. Hsu, I.H. Sarelius, and G.R. Cokelet Fluctuations in microvascular blood flow parameters caused by hemodynamic mechanisms Am J Physiol 266 1994 H1822 H1828
    • (1994) Am J Physiol , vol.266
    • Kiani, M.F.1    Pries, A.R.2    Hsu, L.L.3    Sarelius, I.H.4    Cokelet, G.R.5
  • 17
    • 0028294109 scopus 로고
    • Rates of oxygen consumption for proliferating and quiescent cells isolated from multicellular tumor spheroids
    • J.P. Freyer Rates of oxygen consumption for proliferating and quiescent cells isolated from multicellular tumor spheroids Adv Exp Med Biol 345 1994 335 342
    • (1994) Adv Exp Med Biol , vol.345 , pp. 335-342
    • Freyer, J.P.1
  • 18
    • 0029035872 scopus 로고
    • Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors
    • T.W. Secomb, R. Hsu, E.T. Ong, J.F. Gross, and M.W. Dewhirst Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors Acta Oncol 34 1995 313 316
    • (1995) Acta Oncol , vol.34 , pp. 313-316
    • Secomb, T.W.1    Hsu, R.2    Ong, E.T.3    Gross, J.F.4    Dewhirst, M.W.5
  • 19
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • J.M. Brown, and A.J. Giaccia The unique physiology of solid tumors: opportunities (and problems) for cancer therapy Cancer Res 58 1998 1408 1416
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 20
    • 0032835231 scopus 로고    scopus 로고
    • Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle of rats
    • R. Braun, J. Lanzen, and M. Dewhirst Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle of rats Am J Physiol 277 1999 H551 H568
    • (1999) Am J Physiol , vol.277
    • Braun, R.1    Lanzen, J.2    Dewhirst, M.3
  • 21
    • 0042575345 scopus 로고    scopus 로고
    • Temporal heterogeneity in oxygen tension in human melanoma xenografts
    • K.G. Brurberg, B.A. Graff, and E.K. Rofstad Temporal heterogeneity in oxygen tension in human melanoma xenografts Br J Cancer 89 2003 350 356
    • (2003) Br J Cancer , vol.89 , pp. 350-356
    • Brurberg, K.G.1    Graff, B.A.2    Rofstad, E.K.3
  • 22
    • 0029024240 scopus 로고
    • Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours
    • D.J. Chaplin, and S.A. Hill Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours Br J Cancer 71 1995 1210 1213
    • (1995) Br J Cancer , vol.71 , pp. 1210-1213
    • Chaplin, D.J.1    Hill, S.A.2
  • 23
    • 8944246794 scopus 로고    scopus 로고
    • Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes
    • S.A. Hill, K.H. Pigott, M.I. Saunders, M.E. Powell, S. Arnold, and A. Obeid Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes Br J Cancer 74 Suppl 27 1996 S260 S263
    • (1996) Br J Cancer , vol.74 , Issue.27
    • Hill, S.A.1    Pigott, K.H.2    Saunders, M.I.3    Powell, M.E.4    Arnold, S.5    Obeid, A.6
  • 24
    • 0024365790 scopus 로고
    • The use of fluorescent probes to identify regions of transient perfusion in murine tumors
    • M.J. Trotter, D.J. Chaplin, R.E. Durand, and P.L. Olive The use of fluorescent probes to identify regions of transient perfusion in murine tumors Int J Radiat Oncol Biol Phys 16 1989 931 934
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 931-934
    • Trotter, M.J.1    Chaplin, D.J.2    Durand, R.E.3    Olive, P.L.4
  • 26
    • 0029986979 scopus 로고    scopus 로고
    • Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: A novel mechanism of tumor angiogenesis
    • S. Patan, L.L. Munn, and R.K. Jain Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis Microvasc Res 51 1996 260 272
    • (1996) Microvasc Res , vol.51 , pp. 260-272
    • Patan, S.1    Munn, L.L.2    Jain, R.K.3
  • 27
    • 0032613071 scopus 로고    scopus 로고
    • Blood flow and vascular gene expression: Fluid shear stress as a modulator of endothelial phenotype
    • J.N. Topper, and MA Gimbrone Jr Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype Mol Med Today 5 1999 40 46
    • (1999) Mol Med Today , vol.5 , pp. 40-46
    • Topper, J.N.1    Gimbrone Jr., M.A.2
  • 28
    • 0037288375 scopus 로고    scopus 로고
    • A model for temporal heterogeneities of tumor blood flow
    • F. Mollica, R.K. Jain, and P.A. Netti A model for temporal heterogeneities of tumor blood flow Microvasc Res 65 2003 56 60
    • (2003) Microvasc Res , vol.65 , pp. 56-60
    • Mollica, F.1    Jain, R.K.2    Netti, P.A.3
  • 29
    • 0036895572 scopus 로고    scopus 로고
    • Orally administered pimonidazole to label hypoxic tumor cells
    • K.L. Bennewith, J.A. Raleigh, and R.E. Durand Orally administered pimonidazole to label hypoxic tumor cells Cancer Res 62 2002 6827 6830
    • (2002) Cancer Res , vol.62 , pp. 6827-6830
    • Bennewith, K.L.1    Raleigh, J.A.2    Durand, R.E.3
  • 31
    • 0038115172 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms
    • V.A. Shatrov, V.V. Sumbayev, J. Zhou, and B. Brune Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms Blood 101 2003 4847 4849
    • (2003) Blood , vol.101 , pp. 4847-4849
    • Shatrov, V.A.1    Sumbayev, V.V.2    Zhou, J.3    Brune, B.4
  • 33
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • G.L. Semenza Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 2003 721 732
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 35
    • 0031870738 scopus 로고    scopus 로고
    • The role of carbonic anhydrases in tumors
    • A. Nogradi The role of carbonic anhydrases in tumors Am J Pathol 153 1998 1 4
    • (1998) Am J Pathol , vol.153 , pp. 1-4
    • Nogradi, A.1
  • 36
    • 0035881075 scopus 로고    scopus 로고
    • Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
    • S.K. Chia, C.C. Wykoff, P.H. Watson, C. Han, R.D. Leek, and J. Pastorek Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma J Clin Oncol 19 2001 3660 3668
    • (2001) J Clin Oncol , vol.19 , pp. 3660-3668
    • Chia, S.K.1    Wykoff, C.C.2    Watson, P.H.3    Han, C.4    Leek, R.D.5    Pastorek, J.6
  • 37
    • 0035503362 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
    • A. Giatromanolaki, M.I. Koukourakis, E. Sivridis, J. Pastorek, C.C. Wykoff, and K.C. Gatter Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer Cancer Res 61 2001 7992 7998
    • (2001) Cancer Res , vol.61 , pp. 7992-7998
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Pastorek, J.4    Wykoff, C.C.5    Gatter, K.C.6
  • 38
    • 0035181306 scopus 로고    scopus 로고
    • Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy
    • M.I. Koukourakis, A. Giatromanolaki, E. Sivridis, K. Simopoulos, J. Pastorek, and C.C. Wykoff Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy Clin Cancer Res 7 2001 3399 3403
    • (2001) Clin Cancer Res , vol.7 , pp. 3399-3403
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3    Simopoulos, K.4    Pastorek, J.5    Wykoff, C.C.6
  • 39
    • 0035411026 scopus 로고    scopus 로고
    • The cellular physiology of carbonic anhydrases
    • S. Breton The cellular physiology of carbonic anhydrases JOP 2 2001 159 164
    • (2001) JOP , vol.2 , pp. 159-164
    • Breton, S.1
  • 40
    • 0035392959 scopus 로고    scopus 로고
    • Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density
    • N.J. Beasley, C.C. Wykoff, P.H. Watson, R. Leek, H. Turley, and K. Gatter Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density Cancer Res 61 2001 5262 5267
    • (2001) Cancer Res , vol.61 , pp. 5262-5267
    • Beasley, N.J.1    Wykoff, C.C.2    Watson, P.H.3    Leek, R.4    Turley, H.5    Gatter, K.6
  • 41
    • 0033569442 scopus 로고    scopus 로고
    • The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
    • A.P. Halestrap, and N.T. Price The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation Biochem J 343 Pt 2 1999 281 299
    • (1999) Biochem J , vol.343 , Issue.2 , pp. 281-299
    • Halestrap, A.P.1    Price, N.T.2
  • 42
    • 0025144124 scopus 로고
    • Soft-tissue sarcomas: Detection of metabolic heterogeneity with P-31 MR spectroscopy
    • H.D. Sostman, H.C. Charles, S. Rockwell, K. Leopold, C. Beam, and D. Madwed Soft-tissue sarcomas: detection of metabolic heterogeneity with P-31 MR spectroscopy Radiology 176 1990 837 843
    • (1990) Radiology , vol.176 , pp. 837-843
    • Sostman, H.D.1    Charles, H.C.2    Rockwell, S.3    Leopold, K.4    Beam, C.5    Madwed, D.6
  • 44
    • 0029397772 scopus 로고
    • MR spectroscopy of musculoskeletal soft-tissue tumors
    • W.G. Negendank MR spectroscopy of musculoskeletal soft-tissue tumors Magn Reson Imaging Clin North Am 3 1995 713 725
    • (1995) Magn Reson Imaging Clin North Am , vol.3 , pp. 713-725
    • Negendank, W.G.1
  • 47
    • 0024493051 scopus 로고
    • The relationship between the unmodified initial tissue pH of human tumours and the response to combined radiotherapy and local hyperthermia treatment
    • A.P. van den Berg, J.L. Wike-Hooley, M.P. Broekmeyer-Reurink, J. van der Zee, and H.S. Reinhold The relationship between the unmodified initial tissue pH of human tumours and the response to combined radiotherapy and local hyperthermia treatment Eur J Cancer Clin Oncol 25 1989 73 78
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 73-78
    • Van Den Berg, A.P.1    Wike-Hooley, J.L.2    Broekmeyer-Reurink, M.P.3    Van Der Zee, J.4    Reinhold, H.S.5
  • 50
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxiaâ€"a key regulatory factor in tumour growth
    • A.L. Harris Hypoxiaâ€"a key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 51
    • 0026596473 scopus 로고
    • Oxygen distribution and consumption in the cat retina during normoxia and hypoxemia
    • R.A. Linsenmeier, and R.D. Braun Oxygen distribution and consumption in the cat retina during normoxia and hypoxemia J Gen Physiol 99 1992 177 197
    • (1992) J Gen Physiol , vol.99 , pp. 177-197
    • Linsenmeier, R.A.1    Braun, R.D.2
  • 53
    • 0033808725 scopus 로고    scopus 로고
    • Oxygen regulation of gene expression: A study in opposites
    • C.T. D'Angio, and J.N. Finkelstein Oxygen regulation of gene expression: a study in opposites Mol Genet Metab 71 2000 371 380
    • (2000) Mol Genet Metab , vol.71 , pp. 371-380
    • D'Angio, C.T.1    Finkelstein, J.N.2
  • 54
    • 0038756445 scopus 로고    scopus 로고
    • PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: Evidence for an effect on the tumor and endothelial compartment
    • J.D. Su, L.D. Mayo, D.B. Donner, and D.L. Durden PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment Cancer Res 63 2003 3585 3592
    • (2003) Cancer Res , vol.63 , pp. 3585-3592
    • Su, J.D.1    Mayo, L.D.2    Donner, D.B.3    Durden, D.L.4
  • 55
    • 0033572417 scopus 로고    scopus 로고
    • Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation
    • R. Alarcon, C. Koumenis, R.K. Geyer, C.G. Maki, and A.J. Giaccia Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation Cancer Res 59 1999 6046 6051
    • (1999) Cancer Res , vol.59 , pp. 6046-6051
    • Alarcon, R.1    Koumenis, C.2    Geyer, R.K.3    Maki, C.G.4    Giaccia, A.J.5
  • 56
    • 0242710750 scopus 로고    scopus 로고
    • Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase gene family (PFKFB-1â€"4) expression in vivo
    • O. Minchenko, I. Opentanova, and J. Caro Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1â€"4) expression in vivo FEBS Lett 554 2003 264 270
    • (2003) FEBS Lett , vol.554 , pp. 264-270
    • Minchenko, O.1    Opentanova, I.2    Caro, J.3
  • 57
    • 0030771009 scopus 로고    scopus 로고
    • Altered proton extrusion in cells adapted to growth at low extracellular pH
    • C.S. Owen, P.M. Pooler, M.L. Wahl, R.A. Coss, and D.B. Leeper Altered proton extrusion in cells adapted to growth at low extracellular pH J Cell Physiol 173 1997 397 405
    • (1997) J Cell Physiol , vol.173 , pp. 397-405
    • Owen, C.S.1    Pooler, P.M.2    Wahl, M.L.3    Coss, R.A.4    Leeper, D.B.5
  • 58
    • 0034058373 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation
    • S.J. Reshkin, A. Bellizzi, V. Albarani, L. Guerra, M. Tommasino, and A. Paradiso Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation J Biol Chem 275 2000 5361 5369
    • (2000) J Biol Chem , vol.275 , pp. 5361-5369
    • Reshkin, S.J.1    Bellizzi, A.2    Albarani, V.3    Guerra, L.4    Tommasino, M.5    Paradiso, A.6
  • 60
    • 0036347515 scopus 로고    scopus 로고
    • Lactate stimulates fibroblast expression of hyaluronan and CD44: The Warburg effect revisited
    • R. Stern, S. Shuster, B.A. Neudecker, and B. Formby Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited Exp Cell Res 276 2002 24 31
    • (2002) Exp Cell Res , vol.276 , pp. 24-31
    • Stern, R.1    Shuster, S.2    Neudecker, B.A.3    Formby, B.4
  • 61
    • 0035810936 scopus 로고    scopus 로고
    • Endothelial cell surface F1â€"F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin
    • T.L. Moser, D.J. Kenan, T.A. Ashley, J.A. Roy, M.D. Goodman, and U.K. Misra Endothelial cell surface F1â€"F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin Proc Natl Acad Sci U S A 98 2001 6656 6661
    • (2001) Proc Natl Acad Sci U S a , vol.98 , pp. 6656-6661
    • Moser, T.L.1    Kenan, D.J.2    Ashley, T.A.3    Roy, J.A.4    Goodman, M.D.5    Misra, U.K.6
  • 63
    • 0036041980 scopus 로고    scopus 로고
    • Angiostatin induces intracellular acidosis and anoikis in endothelial cells at a tumor-like low pH
    • M.L. Wahl, C.S. Owen, and D.S. Grant Angiostatin induces intracellular acidosis and anoikis in endothelial cells at a tumor-like low pH Endothelium 9 2002 205 216
    • (2002) Endothelium , vol.9 , pp. 205-216
    • Wahl, M.L.1    Owen, C.S.2    Grant, D.S.3
  • 64
    • 0035881307 scopus 로고    scopus 로고
    • Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo
    • D. Fukumura, L. Xu, Y. Chen, T. Gohongi, B. Seed, and R.K. Jain Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo Cancer Res 61 2001 6020 6024
    • (2001) Cancer Res , vol.61 , pp. 6020-6024
    • Fukumura, D.1    Xu, L.2    Chen, Y.3    Gohongi, T.4    Seed, B.5    Jain, R.K.6
  • 65
    • 0037192802 scopus 로고    scopus 로고
    • Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: Mechanism of low pH-induced VEGF
    • L. Xu, D. Fukumura, and R.K. Jain Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF J Biol Chem 277 2002 11368 11374
    • (2002) J Biol Chem , vol.277 , pp. 11368-11374
    • Xu, L.1    Fukumura, D.2    Jain, R.K.3
  • 67
    • 0027936404 scopus 로고
    • Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia
    • K.S. Yao, S. Xanthoudakis, T. Curran, and P.J. O'Dwyer Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia Mol Cell Biol 14 1994 5997 6003
    • (1994) Mol Cell Biol , vol.14 , pp. 5997-6003
    • Yao, K.S.1    Xanthoudakis, S.2    Curran, T.3    O'Dwyer, P.J.4
  • 68
    • 0035400504 scopus 로고    scopus 로고
    • Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts
    • V. Vukovic, T. Nicklee, and D.W. Hedley Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts Radiother Oncol 60 2001 69 73
    • (2001) Radiother Oncol , vol.60 , pp. 69-73
    • Vukovic, V.1    Nicklee, T.2    Hedley, D.W.3
  • 69
    • 0036144680 scopus 로고    scopus 로고
    • Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels
    • P. Kuppusamy, H. Li, G. Ilangovan, A.J. Cardounel, J.L. Zweier, and K. Yamada Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels Cancer Res 62 2002 307 312
    • (2002) Cancer Res , vol.62 , pp. 307-312
    • Kuppusamy, P.1    Li, H.2    Ilangovan, G.3    Cardounel, A.J.4    Zweier, J.L.5    Yamada, K.6
  • 70
    • 0035930627 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite
    • M.C. Duyndam, T.M. Hulscher, D. Fontijn, H.M. Pinedo, and E. Boven Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite J Biol Chem 276 2001 48066 48076
    • (2001) J Biol Chem , vol.276 , pp. 48066-48076
    • Duyndam, M.C.1    Hulscher, T.M.2    Fontijn, D.3    Pinedo, H.M.4    Boven, E.5
  • 71
    • 0030636257 scopus 로고    scopus 로고
    • Angiogenesis and angiogenesis inhibition: An overview
    • J. Folkman Angiogenesis and angiogenesis inhibition: an overview EXS 79 1997 1 8
    • (1997) EXS , vol.79 , pp. 1-8
    • Folkman, J.1
  • 72
    • 0033580889 scopus 로고    scopus 로고
    • Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
    • J. Holash, P.C. Maisonpierre, D. Compton, P. Boland, C.R. Alexander, and D. Zagzag Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF Science 284 1999 1994 1998
    • (1999) Science , vol.284 , pp. 1994-1998
    • Holash, J.1    Maisonpierre, P.C.2    Compton, D.3    Boland, P.4    Alexander, C.R.5    Zagzag, D.6
  • 73
    • 0026362940 scopus 로고
    • Switch to the angiogenic phenotype during tumorigenesis
    • J. Folkman, and D. Hanahan Switch to the angiogenic phenotype during tumorigenesis Princess Takamatsu Symp 22 1991 339 347
    • (1991) Princess Takamatsu Symp , vol.22 , pp. 339-347
    • Folkman, J.1    Hanahan, D.2
  • 74
    • 0042889191 scopus 로고    scopus 로고
    • Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis
    • H. Kimura, and H. Esumi Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis Acta Biochim Pol 50 2003 49 59
    • (2003) Acta Biochim Pol , vol.50 , pp. 49-59
    • Kimura, H.1    Esumi, H.2
  • 75
    • 0035575012 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and vascular targeting of solid tumors
    • R.A. Brekken, and P.E. Thorpe Vascular endothelial growth factor and vascular targeting of solid tumors Anticancer Res 21 2001 4221 4229
    • (2001) Anticancer Res , vol.21 , pp. 4221-4229
    • Brekken, R.A.1    Thorpe, P.E.2
  • 76
    • 0032824155 scopus 로고    scopus 로고
    • Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis
    • Z.A. Haroon, J.M. Hettasch, T.S. Lai, M.W. Dewhirst, and C.S. Greenberg Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis FASEB J 13 1999 1787 1795
    • (1999) FASEB J , vol.13 , pp. 1787-1795
    • Haroon, Z.A.1    Hettasch, J.M.2    Lai, T.S.3    Dewhirst, M.W.4    Greenberg, C.S.5
  • 78
    • 0030460424 scopus 로고    scopus 로고
    • Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
    • S. Davis, T.H. Aldrich, P.F. Jones, A. Acheson, D.L. Compton, and V. Jain Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning Cell 87 1996 1161 1169
    • (1996) Cell , vol.87 , pp. 1161-1169
    • Davis, S.1    Aldrich, T.H.2    Jones, P.F.3    Acheson, A.4    Compton, D.L.5    Jain, V.6
  • 80
    • 0344450778 scopus 로고    scopus 로고
    • Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
    • A. Papapetropoulos, G. Garcia-Cardena, T.J. Dengler, P.C. Maisonpierre, G.D. Yancopoulos, and W.C. Sessa Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors Lab Invest 79 1999 213 223
    • (1999) Lab Invest , vol.79 , pp. 213-223
    • Papapetropoulos, A.1    Garcia-Cardena, G.2    Dengler, T.J.3    Maisonpierre, P.C.4    Yancopoulos, G.D.5    Sessa, W.C.6
  • 81
    • 0034036689 scopus 로고    scopus 로고
    • Angiopoietin-1 protects the adult vasculature against plasma leakage
    • G. Thurston, J.S. Rudge, E. Ioffe, H. Zhou, L. Ross, and S.D. Croll Angiopoietin-1 protects the adult vasculature against plasma leakage Nat Med 6 2000 460 463
    • (2000) Nat Med , vol.6 , pp. 460-463
    • Thurston, G.1    Rudge, J.S.2    Ioffe, E.3    Zhou, H.4    Ross, L.5    Croll, S.D.6
  • 82
    • 8544249876 scopus 로고    scopus 로고
    • Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia
    • B. Enholm, K. Paavonen, A. Ristimaki, V. Kumar, Y. Gunji, and J. Klefstrom Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia Oncogene 14 1997 2475 2483
    • (1997) Oncogene , vol.14 , pp. 2475-2483
    • Enholm, B.1    Paavonen, K.2    Ristimaki, A.3    Kumar, V.4    Gunji, Y.5    Klefstrom, J.6
  • 83
    • 0032547764 scopus 로고    scopus 로고
    • Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia
    • S.J. Mandriota, and M.S. Pepper Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia Circ Res 83 1998 852 859
    • (1998) Circ Res , vol.83 , pp. 852-859
    • Mandriota, S.J.1    Pepper, M.S.2
  • 84
    • 0032985888 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells
    • H. Oh, H. Takagi, K. Suzuma, A. Otani, M. Matsumura, and Y. Honda Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells J Biol Chem 274 1999 15732 15739
    • (1999) J Biol Chem , vol.274 , pp. 15732-15739
    • Oh, H.1    Takagi, H.2    Suzuma, K.3    Otani, A.4    Matsumura, M.5    Honda, Y.6
  • 85
    • 0034757316 scopus 로고    scopus 로고
    • Numerical simulations of angiogenesis in the cornea
    • S. Tong, and F. Yuan Numerical simulations of angiogenesis in the cornea Microvasc Res 61 2001 14 27
    • (2001) Microvasc Res , vol.61 , pp. 14-27
    • Tong, S.1    Yuan, F.2
  • 86
    • 0034684999 scopus 로고    scopus 로고
    • Initial stages of tumor cell-induced angiogenesis: Evaluation via skin window chambers in rodent models
    • C.Y. Li, S. Shan, Q. Huang, R.D. Braun, J. Lanzen, and K. Hu Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models J Natl Cancer Inst 92 2000 143 147
    • (2000) J Natl Cancer Inst , vol.92 , pp. 143-147
    • Li, C.Y.1    Shan, S.2    Huang, Q.3    Braun, R.D.4    Lanzen, J.5    Hu, K.6
  • 87
    • 1442265695 scopus 로고    scopus 로고
    • Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival
    • S. Shan, N.D. Robson, Y. Cao, T. Qiao, C.Y. Li, and C.D. Kontos Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival FASEB J 18 2 2003 326 328
    • (2003) FASEB J , vol.18 , Issue.2 , pp. 326-328
    • Shan, S.1    Robson, N.D.2    Cao, Y.3    Qiao, T.4    Li, C.Y.5    Kontos, C.D.6
  • 88
    • 0036731873 scopus 로고    scopus 로고
    • Intravascular location of breast cancer cells after spontaneous metastasis to the lung
    • C.W. Wong, C. Song, M.M. Grimes, W. Fu, M.W. Dewhirst, and R.J. Muschel Intravascular location of breast cancer cells after spontaneous metastasis to the lung Am J Pathol 161 2002 749 753
    • (2002) Am J Pathol , vol.161 , pp. 749-753
    • Wong, C.W.1    Song, C.2    Grimes, M.M.3    Fu, W.4    Dewhirst, M.W.5    Muschel, R.J.6
  • 89
    • 0033972059 scopus 로고    scopus 로고
    • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
    • A.B. Al-Mehdi, K. Tozawa, A.B. Fisher, L. Shientag, A. Lee, and R.J. Muschel Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis Nat Med 6 2000 100 102
    • (2000) Nat Med , vol.6 , pp. 100-102
    • Al-Mehdi, A.B.1    Tozawa, K.2    Fisher, A.B.3    Shientag, L.4    Lee, A.5    Muschel, R.J.6
  • 90
    • 0036948242 scopus 로고    scopus 로고
    • Intussusceptive angiogenesisâ€"the alternative to capillary sprouting
    • P.H. Burri, and V. Djonov Intussusceptive angiogenesisâ€" the alternative to capillary sprouting Mol Aspects Med 23 2002 S1 S27
    • (2002) Mol Aspects Med , vol.23
    • Burri, P.H.1    Djonov, V.2
  • 91
    • 0035862992 scopus 로고    scopus 로고
    • Vascular remodeling during the normal and malignant life cycle of the mammary gland
    • V. Djonov, A.C. Andres, and A. Ziemiecki Vascular remodeling during the normal and malignant life cycle of the mammary gland Microsci Res Technol 52 2001 182 189
    • (2001) Microsci Res Technol , vol.52 , pp. 182-189
    • Djonov, V.1    Andres, A.C.2    Ziemiecki, A.3
  • 92
    • 0242573142 scopus 로고    scopus 로고
    • Vascular remodeling by intussusceptive angiogenesis
    • V. Djonov, O. Baum, and P.H. Burri Vascular remodeling by intussusceptive angiogenesis Cell Tissue Res 314 2003 107 117
    • (2003) Cell Tissue Res , vol.314 , pp. 107-117
    • Djonov, V.1    Baum, O.2    Burri, P.H.3
  • 93
    • 0036794753 scopus 로고    scopus 로고
    • Angioadaptation: Keeping the vascular system in shape
    • A. Zakrzewicz, T.W. Secomb, and A.R. Pries Angioadaptation: keeping the vascular system in shape News Physiol Sci 17 2002 197 201
    • (2002) News Physiol Sci , vol.17 , pp. 197-201
    • Zakrzewicz, A.1    Secomb, T.W.2    Pries, A.R.3
  • 94
    • 0038104888 scopus 로고    scopus 로고
    • Structural response of microcirculatory networks to changes in demand: Information transfer by shear stress
    • A.R. Pries, B. Reglin, and T.W. Secomb Structural response of microcirculatory networks to changes in demand: information transfer by shear stress Am J Physiol Heart Circ Physiol 284 2003 H2204 H2212
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Pries, A.R.1    Reglin, B.2    Secomb, T.W.3
  • 95
    • 0033962899 scopus 로고    scopus 로고
    • Early wound healing exhibits cytokine surge without evidence of hypoxia
    • Z.A. Haroon, J.A. Raleigh, C.S. Greenberg, and M.W. Dewhirst Early wound healing exhibits cytokine surge without evidence of hypoxia Ann Surg 231 2000 137 147
    • (2000) Ann Surg , vol.231 , pp. 137-147
    • Haroon, Z.A.1    Raleigh, J.A.2    Greenberg, C.S.3    Dewhirst, M.W.4
  • 96
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • T.G. Graeber, C. Osmanian, T. Jacks, D.E. Housman, C.J. Koch, and S.W. Lowe Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 1996 88 91
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3    Housman, D.E.4    Koch, C.J.5    Lowe, S.W.6
  • 97
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • H.F. Dvorak Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing N Engl J Med 315 1986 1650 1659
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 98
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • R.K. Jain Molecular regulation of vessel maturation Nat Med 9 2003 685 693
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.