메뉴 건너뛰기




Volumn 50, Issue 1, 2003, Pages 49-59

Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis

Author keywords

Angiogenesis; Hypoxia; Hypoxia inducible factor 1; Nitric oxide; Reciprocal regulation; Vascular endothelial growth factor

Indexed keywords

HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE B; PROTEIN KINASE C; TRANSCRIPTION FACTOR; VASCULOTROPIN;

EID: 0042889191     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2003_3713     Document Type: Review
Times cited : (235)

References (69)
  • 2
    • 0037134442 scopus 로고    scopus 로고
    • Lack of evidence for the involvement of the phosphoinositide 3-kinase/ Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension
    • Alvarez-Tejado M, Alfranca A, Aragones J, Vara A, Landazuri MO, del Peso L. (2002) Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension. J Biol Chem.; 277: 13508-17.
    • (2002) J Biol Chem , vol.277 , pp. 13508-13517
    • Alvarez-Tejado, M.1    Alfranca, A.2    Aragones, J.3    Vara, A.4    Landazuri, M.O.5    Del Peso, L.6
  • 3
    • 0037177867 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription
    • Arsham AM, Plas DR, Thompson CB, Simon MC. (2002) Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. J Biol Chem.; 277: 15162-70.
    • (2002) J Biol Chem , vol.277 , pp. 15162-15170
    • Arsham, A.M.1    Plas, D.R.2    Thompson, C.B.3    Simon, M.C.4
  • 5
    • 0035477438 scopus 로고    scopus 로고
    • Effects of ras and von Hippel-Lindau. (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α HIF-2α and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway
    • Blancher C, Moore JW, Robertson N, Harris AL. (2001) Effects of ras and von Hippel-Lindau. (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α HIF-2α and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway. Cancer Res.; 61: 7349-55.
    • (2001) Cancer Res , vol.61 , pp. 7349-7355
    • Blancher, C.1    Moore, J.W.2    Robertson, N.3    Harris, A.L.4
  • 7
    • 0035980110 scopus 로고    scopus 로고
    • 2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells
    • 2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. J Biol Chem.; 276: 32663-9.
    • (2001) J Biol Chem , vol.276 , pp. 32663-32669
    • Brouet, A.1    Sonveaux, P.2    Dessy, C.3    Balligand, J.L.4    Feron, O.5
  • 8
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick RK, McKnight SL. (2001) A conserved family of prolyl-4-hydroxylases that modify HIF. Science.; 294: 1337-40.
    • (2001) Science , vol.294 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 9
    • 0025008449 scopus 로고
    • Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells
    • Busse R, Mulsch A. (1990) Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett.; 275: 87-90.
    • (1990) FEBS Lett , vol.275 , pp. 87-90
    • Busse, R.1    Mulsch, A.2
  • 10
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. (2000) Mechanisms of angiogenesis and arteriogenesis. Nat Med.; 6: 389-95.
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 12
    • 0030865655 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells
    • Chin K, Kurashima Y, Ogura T, Tajiri H, Yoshida S, Esumi H. (1997) Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells. Oncogene.; 15: 437-42.
    • (1997) Oncogene , vol.15 , pp. 437-442
    • Chin, K.1    Kurashima, Y.2    Ogura, T.3    Tajiri, H.4    Yoshida, S.5    Esumi, H.6
  • 14
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature.; 399: 601-5.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 18
    • 0033566693 scopus 로고    scopus 로고
    • Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
    • Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, Semenza GL. (1999) Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res.; 59: 3915-8.
    • (1999) Cancer Res , vol.59 , pp. 3915-3918
    • Feldser, D.1    Agani, F.2    Iyer, N.V.3    Pak, B.4    Ferreira, G.5    Semenza, G.L.6
  • 19
    • 0033525718 scopus 로고    scopus 로고
    • VEGF induces nuclear translocation of Flk-1/KDR endothelial nitric oxide synthase and caveolin-1 in vascular endothelial cells
    • Feng Y, Venema VJ, Venema RC, Tsai N, Caldwell RB. (1999) VEGF induces nuclear translocation of Flk-1/KDR endothelial nitric oxide synthase and caveolin-1 in vascular endothelial cells. Biochem Biophys Res Commun.; 256: 192-7.
    • (1999) Biochem Biophys Res Commun , vol.256 , pp. 192-197
    • Feng, Y.1    Venema, V.J.2    Venema, R.C.3    Tsai, N.4    Caldwell, R.B.5
  • 20
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV. (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature.; 288: 373-6.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 21
    • 0036899189 scopus 로고    scopus 로고
    • Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: Role of PI3K PKC and PLC pathways
    • Gelinas DS, Bernatchez PN, Rollin S, Bazan NG, Sirois MG. (2002) Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K PKC and PLC pathways. Br J Pharmacol.; 137: 1021-30.
    • (2002) Br J Pharmacol , vol.137 , pp. 1021-1030
    • Gelinas, D.S.1    Bernatchez, P.N.2    Rollin, S.3    Bazan, N.G.4    Sirois, M.G.5
  • 22
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N. (1998) Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem.; 273: 30336-43.
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Keyt, B.A.5    Dixit, V.6    Ferrara, N.7
  • 23
    • 0018311634 scopus 로고
    • Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide nitroprusside and a carcinogenic nitrosoamine
    • Gruetter CA, Barry BK, McNamara DB, Gruetter DY, Kadowitz PJ, Ignarro L. (1979) Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide nitroprusside and a carcinogenic nitrosoamine. J Cyclic Nucleotide Res.; 5: 211-24.
    • (1979) J Cyclic Nucleotide Res , vol.5 , pp. 211-224
    • Gruetter, C.A.1    Barry, B.K.2    McNamara, D.B.3    Gruetter, D.Y.4    Kadowitz, P.J.5    Ignarro, L.6
  • 24
    • 0033609922 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src
    • He H, Venema VJ, Gu X, Venema RC, Marrero MB, Caldwell RB. (1999) Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src. J Biol Chem.; 274: 25130-5.
    • (1999) J Biol Chem , vol.274 , pp. 25130-25135
    • He, H.1    Venema, V.J.2    Gu, X.3    Venema, R.C.4    Marrero, M.B.5    Caldwell, R.B.6
  • 26
    • 0033605676 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling
    • Huang LE, Willmore WG, Gu J, Goldberg MA, Bunn HF. (1999) Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling. J Biol Chem.; 274: 9038-44.
    • (1999) J Biol Chem , vol.274 , pp. 9038-9044
    • Huang, L.E.1    Willmore, W.G.2    Gu, J.3    Goldberg, M.A.4    Bunn, H.F.5
  • 27
    • 0026551016 scopus 로고
    • Haem-dependent activation of cytosolic guanylate cyclase by nitric oxide: A widespread signal transduction mechanism
    • Ignarro LJ. (1992) Haem-dependent activation of cytosolic guanylate cyclase by nitric oxide: a widespread signal transduction mechanism. Biochem Soc Trans.; 20: 465-9.
    • (1992) Biochem Soc Trans , vol.20 , pp. 465-469
    • Ignarro, L.J.1
  • 28
    • 0001123777 scopus 로고    scopus 로고
    • Physiology and pathophysiology of nitric oxide
    • Ignarro LJ. (1996) Physiology and pathophysiology of nitric oxide. Kidney Int Suppl.; 55: S2-5.
    • (1996) Kidney Int Suppl , vol.55
    • Ignarro, L.J.1
  • 29
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda E, Achen MG, Breier G, Risau W. (1995) Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem.; 270: 19761-6.
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 30
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway
    • Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L. (1999) Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway. J Biol Chem.; 274: 6519-25.
    • (1999) J Biol Chem , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 31
    • 0036382929 scopus 로고    scopus 로고
    • Effects of nitric oxide donors on vascular endothelial growth factor gene induction
    • Kimura H, Ogura T, Kurashima Y, Weisz A, Esumi H. (2002) Effects of nitric oxide donors on vascular endothelial growth factor gene induction. Biochem Biophys Res Commun.; 296: 976-82.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 976-982
    • Kimura, H.1    Ogura, T.2    Kurashima, Y.3    Weisz, A.4    Esumi, H.5
  • 32
    • 0033975850 scopus 로고    scopus 로고
    • Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: Control of hypoxia-inducible factor-1 activity by nitric oxide
    • Kimura H, Weisz A, Kurashima Y, Hashimoto K, Ogura T, D'Acquisto F, Addeo R, Makuuchi M, Esumi H. (2000) Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. Blood.; 95: 189-97.
    • (2000) Blood , vol.95 , pp. 189-197
    • Kimura, H.1    Weisz, A.2    Kurashima, Y.3    Hashimoto, K.4    Ogura, T.5    D'Acquisto, F.6    Addeo, R.7    Makuuchi, M.8    Esumi, H.9
  • 33
    • 0035910429 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
    • Kimura H, Weisz A, Ogura T, Hitomi Y, Kurashima Y, Hashimoto K, D'Acquisto F, Makuuchi M, Esumi H. (2001) Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J Biol Chem.; 276: 2292-8.
    • (2001) J Biol Chem , vol.276 , pp. 2292-2298
    • Kimura, H.1    Weisz, A.2    Ogura, T.3    Hitomi, Y.4    Kurashima, Y.5    Hashimoto, K.6    D'Acquisto, F.7    Makuuchi, M.8    Esumi, H.9
  • 34
    • 0030265393 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptors
    • Klagsbrun M, D'Amore PA. (1996) Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev.; 7: 259-70.
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 259-270
    • Klagsbrun, M.1    D'Amore, P.A.2
  • 35
    • 0028349156 scopus 로고
    • Nitric oxide synthases in mammals
    • Knowles RG, Moncada S. (1994) Nitric oxide synthases in mammals. Biochem J.; 298: 249-58.
    • (1994) Biochem J , vol.298 , pp. 249-258
    • Knowles, R.G.1    Moncada, S.2
  • 37
    • 0032573554 scopus 로고    scopus 로고
    • VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2. (KDR)
    • Kroll J, Waltenberger J. (1998) VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2. (KDR). Biochem Biophys Res Commun.; 252: 743-6.
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 743-746
    • Kroll, J.1    Waltenberger, J.2
  • 38
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. (2001) HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol.; 21: 3995-4004.
    • (2001) Mol Cell Biol , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 39
    • 0030044039 scopus 로고    scopus 로고
    • Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
    • Levy AP, Levy NS, Goldberg MA. (1996) Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J Biol Chem.; 271: 2746-53.
    • (1996) J Biol Chem , vol.271 , pp. 2746-2753
    • Levy, A.P.1    Levy, N.S.2    Goldberg, M.A.3
  • 40
    • 0032511014 scopus 로고    scopus 로고
    • Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer
    • Liu Y, Christou H, Morita T, Laughner E, Semenza GL, Kourembanas S. (1998) Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer. J Biol Chem. ; 273: 15257-62.
    • (1998) J Biol Chem , vol.273 , pp. 15257-15262
    • Liu, Y.1    Christou, H.2    Morita, T.3    Laughner, E.4    Semenza, G.L.5    Kourembanas, S.6
  • 41
    • 0032431037 scopus 로고    scopus 로고
    • Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
    • Marti HH, Risau W. (1998) Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci U S A.; 95: 15809-14.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15809-15814
    • Marti, H.H.1    Risau, W.2
  • 43
    • 0028651863 scopus 로고
    • Nitric oxide/cyclic GMP-mediated signal transduction
    • Mayer B. (1994) Nitric oxide/cyclic GMP-mediated signal transduction. Ann N Y Acad Sci.; 733: 357-64.
    • (1994) Ann N Y Acad Sci , vol.733 , pp. 357-364
    • Mayer, B.1
  • 46
    • 2642597076 scopus 로고    scopus 로고
    • Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
    • Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC. (1997) Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest.; 100: 3131-9.
    • (1997) J Clin Invest , vol.100 , pp. 3131-3139
    • Papapetropoulos, A.1    Garcia-Cardena, G.2    Madri, J.A.3    Sessa, W.C.4
  • 47
    • 0032512822 scopus 로고    scopus 로고
    • Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase 1/2 activation in postcapillary endothelium
    • Parenti A, Morbidelli L, Cui XL, Douglas JG, Hood JD, Granger HJ, Ledda F, Ziche M. (1998) Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase 1/2 activation in postcapillary endothelium. J Biol Chem.; 273: 4220-6.
    • (1998) J Biol Chem , vol.273 , pp. 4220-4226
    • Parenti, A.1    Morbidelli, L.2    Cui, X.L.3    Douglas, J.G.4    Hood, J.D.5    Granger, H.J.6    Ledda, F.7    Ziche, M.8
  • 48
    • 0032725554 scopus 로고    scopus 로고
    • p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha. (HIF-1α) and enhance the transcriptional activity of HIF-1
    • Richard DE, Berra E, Gothie E, Roux D, Pouyssegur J. (1999) p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha. (HIF-1α) and enhance the transcriptional activity of HIF-1. J Biol Chem. ; 274: 32631-7.
    • (1999) J Biol Chem , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie, E.3    Roux, D.4    Pouyssegur, J.5
  • 50
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α. (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • Salceda S, Caro J. (1997) Hypoxia-inducible factor 1α. (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem.; 272: 22642-7.
    • (1997) J Biol Chem , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 51
    • 0035864361 scopus 로고    scopus 로고
    • Accumulation of HIF-1α under the influence of nitric oxide
    • Sandau KB, Fandrey J, Brune B. (2001) Accumulation of HIF-1α under the influence of nitric oxide. Blood.; 97: 1009-15.
    • (2001) Blood , vol.97 , pp. 1009-1015
    • Sandau, K.B.1    Fandrey, J.2    Brune, B.3
  • 52
    • 0034638623 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway
    • Sandau KB, Faus HG, Brune B. (2000) Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway. Biochem Biophys Res Commun.; 278: 263-7.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 263-267
    • Sandau, K.B.1    Faus, H.G.2    Brune, B.3
  • 53
    • 0028128416 scopus 로고
    • NO at work
    • Schmidt HH, Walter U. (1994) NO at work. Cell.; 78: 919-25.
    • (1994) Cell , vol.78 , pp. 919-925
    • Schmidt, H.H.1    Walter, U.2
  • 55
    • 0032730327 scopus 로고    scopus 로고
    • Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway
    • Shen BQ, Lee DY, Zioncheck TF. (1999) Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway. J Biol Chem.; 274: 33057-63.
    • (1999) J Biol Chem , vol.274 , pp. 33057-33063
    • Shen, B.Q.1    Lee, D.Y.2    Zioncheck, T.F.3
  • 56
    • 0035860246 scopus 로고    scopus 로고
    • MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF
    • Sodhi A, Montaner S, Miyazaki H, Gutkind JS. (2001) MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF. Biochem Biophys Res Commun.; 287: 292-300.
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 292-300
    • Sodhi, A.1    Montaner, S.2    Miyazaki, H.3    Gutkind, J.S.4
  • 58
    • 0037070223 scopus 로고    scopus 로고
    • Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway
    • Stiehl DP, Jelkmann W, Wenger RH, Hellwig-Burgel T. (2002) Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway. FEBS Lett.; 512: 157-62.
    • (2002) FEBS Lett , vol.512 , pp. 157-162
    • Stiehl, D.P.1    Jelkmann, W.2    Wenger, R.H.3    Hellwig-Burgel, T.4
  • 59
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor protein
    • Tanimoto K, Makino Y, Pereira T, Poellinger L. (2000) Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor protein. EMBO J.; 19: 4298-309.
    • (2000) EMBO J , vol.19 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 60
    • 0033538057 scopus 로고    scopus 로고
    • The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling
    • Thakker GD, Hajjar DP, Muller WA, Rosengart TK. (1999) The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J Biol Chem.; 274: 10002-7.
    • (1999) J Biol Chem , vol.274 , pp. 10002-10007
    • Thakker, G.D.1    Hajjar, D.P.2    Muller, W.A.3    Rosengart, T.K.4
  • 61
    • 0037127297 scopus 로고    scopus 로고
    • Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells
    • Thuringer D, Maulon L, Frelin C. (2002) Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells. J Biol Chem.; 277: 2028-32.
    • (2002) J Biol Chem , vol.277 , pp. 2028-2032
    • Thuringer, D.1    Maulon, L.2    Frelin, C.3
  • 63
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL. (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem.; 270: 1230-7.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 64
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory cytotoxic and cytoprotective mechanisms of nitric oxide
    • Wink DA, Mitchell JB. (1998) Chemical biology of nitric oxide: Insights into regulatory cytotoxic and cytoprotective mechanisms of nitric oxide. Free Radical Biol Med.; 25: 434-56.
    • (1998) Free Radical Biol Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 65
    • 0032987731 scopus 로고    scopus 로고
    • Role of phospholipase C protein kinase C and calcium in VEGF-induced venular hyperpermeability
    • Wu HM, Yuan Y, Zawieja DC, Tinsley J, Granger HJ. (1999) Role of phospholipase C protein kinase C and calcium in VEGF-induced venular hyperpermeability. Am J Physiol.; 276: H535-42.
    • (1999) Am J Physiol , vol.276
    • Wu, H.M.1    Yuan, Y.2    Zawieja, D.C.3    Tinsley, J.4    Granger, H.J.5
  • 67
    • 0032169214 scopus 로고    scopus 로고
    • Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT
    • Zelzer E, Levy Y, Kahana C, Shilo BZ, Rubinstein M, Cohen B. (1998) Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT. EMBO J.; 17: 5085-94.
    • (1998) EMBO J , vol.17 , pp. 5085-5094
    • Zelzer, E.1    Levy, Y.2    Kahana, C.3    Shilo, B.Z.4    Rubinstein, M.5    Cohen, B.6
  • 68
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. (2000) Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res.; 60: 1541-5.
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.