-
1
-
-
0018939225
-
Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme a reductase and a cholesterol-lowering agent
-
Alberts AW, Chen J, Kuron G, Huff V, Hoffman C, Rothrock J, Lopez M, Joshua H, Harris E, Petchad A et al. (1980) Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc Natl Acad Sci USA 77: 3957-3961
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 3957-3961
-
-
Alberts, A.W.1
Chen, J.2
Kuron, G.3
Huff, V.4
Hoffman, C.5
Rothrock, J.6
Lopez, M.7
Joshua, H.8
Harris, E.9
Petchad, A.10
-
2
-
-
0242574984
-
In silico atomic tracing by substrate-product relationships in Escherichia coli intermediary metabolism
-
Arita M (2003) In silico atomic tracing by substrate-product relationships in Escherichia coli intermediary metabolism. Genome Res 13: 2455-2466
-
(2003)
Genome Res
, vol.13
, pp. 2455-2466
-
-
Arita, M.1
-
4
-
-
0003182856
-
Isoprenoid biosynthesis overview
-
DE Cane, ed, Elsevier Science Ltd, Amsterdam
-
Cane DE (1999) Isoprenoid biosynthesis overview. In DE Cane, ed, Comprehensive Natural Product Chemistry, Vol 2. Elsevier Science Ltd, Amsterdam, pp 1-13
-
(1999)
Comprehensive Natural Product Chemistry
, vol.2
, pp. 1-13
-
-
Cane, D.E.1
-
5
-
-
0032423802
-
The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture
-
Contin A, van der Heijden R, Lefeber AWM, Verpoorte R (1998) The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture. FEBS Lett 434: 413-416
-
(1998)
FEBS Lett
, vol.434
, pp. 413-416
-
-
Contin, A.1
Van Der Heijden, R.2
Lefeber, A.W.M.3
Verpoorte, R.4
-
6
-
-
0014733478
-
On the mechanism of iridoid and secoiridoid monoterpene biosynthesis
-
Coscia CJ, Botta L, Guarnaccia R (1970) On the mechanism of iridoid and secoiridoid monoterpene biosynthesis. Arch Biochem Biophys 136: 498-506
-
(1970)
Arch Biochem Biophys
, vol.136
, pp. 498-506
-
-
Coscia, C.J.1
Botta, L.2
Guarnaccia, R.3
-
9
-
-
0026356006
-
13C-NMR spectra of camptothecin and derivatives
-
13C-NMR spectra of camptothecin and derivatives. J Natural Prod 54: 1645-1650
-
(1991)
J Natural Prod
, vol.54
, pp. 1645-1650
-
-
Ezell, E.L.1
Smith, L.L.2
-
10
-
-
0035213439
-
Studies on the nonmevalonate pathway of terpene biosynthesis: The role of 2C-methyl-D-erythritol 2,4-cyclodiphosphate in plants
-
Fellermeier M, Raschke M, Sagner S, Wungsintaweekul J, Schuhr CA, Hecht S, Kis K, Radykewicz T, Adam P, Rohdich F et al. (2001) Studies on the nonmevalonate pathway of terpene biosynthesis: the role of 2C-methyl-D- erythritol 2,4-cyclodiphosphate in plants. Eur J Biochem 268: 6302-6310
-
(2001)
Eur J Biochem
, vol.268
, pp. 6302-6310
-
-
Fellermeier, M.1
Raschke, M.2
Sagner, S.3
Wungsintaweekul, J.4
Schuhr, C.A.5
Hecht, S.6
Kis, K.7
Radykewicz, T.8
Adam, P.9
Rohdich, F.10
-
11
-
-
0014276538
-
Nutrient requirements of suspension cultures of soybean root cells
-
Gamborg OL, Miller RA, Ojima K (1968) Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res 50: 151-158
-
(1968)
Exp Cell Res
, vol.50
, pp. 151-158
-
-
Gamborg, O.L.1
Miller, R.A.2
Ojima, K.3
-
12
-
-
0035102856
-
Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism: Metabolic flux in developing maize kernels
-
Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W (2001) Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism: metabolic flux in developing maize kernels. Plant Physiol 125: 1178-1186
-
(2001)
Plant Physiol
, vol.125
, pp. 1178-1186
-
-
Glawischnig, E.1
Gierl, A.2
Tomas, A.3
Bacher, A.4
Eisenreich, W.5
-
13
-
-
0036918772
-
Starch biosynthesis and intermediary metabolism in maize kernels: Quantitative analysis of metabolite flux by nuclear magnetic resonance
-
Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W (2002) Starch biosynthesis and intermediary metabolism in maize kernels: quantitative analysis of metabolite flux by nuclear magnetic resonance. Plant Physiol 130: 1717-1727
-
(2002)
Plant Physiol
, vol.130
, pp. 1717-1727
-
-
Glawischnig, E.1
Gierl, A.2
Tomas, A.3
Bacher, A.4
Eisenreich, W.5
-
14
-
-
0036240108
-
Improved anthraquinone accumulation in cell cultures of Cinchona "Robusta" by feeding of biosynthetic precursors and inhibitors
-
Han Y-S, van der Heijden R, Verpoorte R (2002) Improved anthraquinone accumulation in cell cultures of Cinchona "Robusta" by feeding of biosynthetic precursors and inhibitors. Biotechnol Lett 24: 705-710
-
(2002)
Biotechnol Lett
, vol.24
, pp. 705-710
-
-
Han, Y.-S.1
Van Der Heijden, R.2
Verpoorte, R.3
-
15
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang YH, Hertzberg R, Hecht S, Liu LF (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260: 14873-14878
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
16
-
-
0001153463
-
Biosynthesis of camptothecin: III. Definition of strictosamide as the penultimate biosynthetic precursor assisted by carbon-13 and deuterium NMR spectroscopy
-
Hutchinson CR, Heckendorf AH, Straughn JL, Daddona PE, in part, Cane DE (1979) Biosynthesis of camptothecin: III. Definition of strictosamide as the penultimate biosynthetic precursor assisted by carbon-13 and deuterium NMR spectroscopy. J Am Chem Soc 101: 3358-3369
-
(1979)
J Am Chem Soc
, vol.101
, pp. 3358-3369
-
-
Hutchinson, C.R.1
Heckendorf, A.H.2
Straughn, J.L.3
Daddona, P.E.4
Cane, D.E.5
-
18
-
-
0037020821
-
Camptothecin-related alkaloids from hairy roots of Ophiorrhiza pumila
-
Kitajima M, Yoshida S, Yamagata K, Nakamura M, Takayama H, Saito K, Seki H, Aimi N (2002) Camptothecin-related alkaloids from hairy roots of Ophiorrhiza pumila. Tetrahedron 58: 9169-9178
-
(2002)
Tetrahedron
, vol.58
, pp. 9169-9178
-
-
Kitajima, M.1
Yoshida, S.2
Yamagata, K.3
Nakamura, M.4
Takayama, H.5
Saito, K.6
Seki, H.7
Aimi, N.8
-
19
-
-
0027546460
-
Strictosidine: From alkaloid to enzyme to gene
-
Kutchan TM (1993) Strictosidine: from alkaloid to enzyme to gene. Phytochemistry 32: 493-506
-
(1993)
Phytochemistry
, vol.32
, pp. 493-506
-
-
Kutchan, T.M.1
-
20
-
-
0037394552
-
Diversity of the biosynthesis of isoprene units
-
Kuzuyama T, Seto H (2003) Diversity of the biosynthesis of isoprene units. Nat Prod Rep 20: 171-183
-
(2003)
Nat Prod Rep
, vol.20
, pp. 171-183
-
-
Kuzuyama, T.1
Seto, H.2
-
21
-
-
0032558613
-
Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis
-
Kuzuyama T, Shimizu T, Takahashi S, Seto H (1998) Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis. Tetrahedron Lett 39: 7913-7916
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 7913-7916
-
-
Kuzuyama, T.1
Shimizu, T.2
Takahashi, S.3
Seto, H.4
-
22
-
-
0032580385
-
Shikonin: A geranyl diphosphate-derived plant hemiterpenoid formed via the mevalonate pathway
-
Li S-M, Henning S, Heide L (1998) Shikonin: a geranyl diphosphate-derived plant hemiterpenoid formed via the mevalonate pathway. Tetrahedron Lett 39: 2721-2724
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 2721-2724
-
-
Li, S.-M.1
Henning, S.2
Heide, L.3
-
23
-
-
0025059108
-
13C-nmr assignments of camptothecine and 10- hydroxycamprorhecine
-
13C-nmr assignments of camptothecine and 10-hydroxycamprorhecine. J Natural Prod 53: 186-189
-
(1990)
J Natural Prod
, vol.53
, pp. 186-189
-
-
Lin, L.Z.1
Cordell, G.A.2
-
25
-
-
0038460047
-
AraCys: A biochemical pathway database for Arabidopsis
-
Mueller LA, Zhang P, Rhee SY (2003) AraCys: a biochemical pathway database for Arabidopsis. Plant Physiol 132: 453-460
-
(2003)
Plant Physiol
, vol.132
, pp. 453-460
-
-
Mueller, L.A.1
Zhang, P.2
Rhee, S.Y.3
-
26
-
-
0036851226
-
Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics
-
Rodríguez-Concepción M, Boronat A (2002) Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics. Plant Physiol 130: 1079-1089
-
(2002)
Plant Physiol
, vol.130
, pp. 1079-1089
-
-
Rodríguez-Concepción, M.1
Boronat, A.2
-
27
-
-
0037452578
-
The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reactions catalyzed by IspG and IspH protein
-
Rohdich F, Zepeck F, Adam P, Hecht S, Kaiser J, Laupitz R, Grawert T, Amslinger S, Eisenreich W, Bacher A et al. (2003) The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein. Proc Natl Acad Sci USA 100: 1586-1591
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1586-1591
-
-
Rohdich, F.1
Zepeck, F.2
Adam, P.3
Hecht, S.4
Kaiser, J.5
Laupitz, R.6
Grawert, T.7
Amslinger, S.8
Eisenreich, W.9
Bacher, A.10
-
28
-
-
0002077157
-
A mevalonate-independent route to isopentenyl diphosphate
-
DE Cane, ed, Elsevier Science Ltd., Amsterdam
-
Rohmer M (1999) A mevalonate-independent route to isopentenyl diphosphate. In DE Cane, ed, Comprehensive Natural Product Chemistry, Vol 2. Elsevier Science Ltd., Amsterdam, pp 45-67
-
(1999)
Comprehensive Natural Product Chemistry
, vol.2
, pp. 45-67
-
-
Rohmer, M.1
-
29
-
-
0035045261
-
Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila
-
Saito K, Sudo H, Yamazaki M, Koseki-Nakamura M, Kitajima M, Takayama H, Aimi N (2001) Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila. Plant Cell Rep 20: 267-271
-
(2001)
Plant Cell Rep
, vol.20
, pp. 267-271
-
-
Saito, K.1
Sudo, H.2
Yamazaki, M.3
Koseki-Nakamura, M.4
Kitajima, M.5
Takayama, H.6
Aimi, N.7
-
30
-
-
0013012666
-
Strictosidine: The biosynthetic key to monoterpenoid indole alkaloids
-
JW Kelly ed, Elsevier Science Ltd, Amsterdam
-
Stöckigt J, Ruppert M (1999) Strictosidine: the biosynthetic key to monoterpenoid indole alkaloids. In JW Kelly ed, Comprehensive Natural Products Chemistry, Vol 4. Elsevier Science Ltd, Amsterdam, pp 109-138
-
(1999)
Comprehensive Natural Products Chemistry
, vol.4
, pp. 109-138
-
-
Stöckigt, J.1
Ruppert, M.2
-
31
-
-
37049108698
-
Strictosidine (isovincoside): The key intermediate in the biosynthesis of monoterpenoid indole alkaloids
-
Stöckigt J, Zenk MH (1977) Strictosidine (isovincoside): the key intermediate in the biosynthesis of monoterpenoid indole alkaloids. J Chem Soc Chem Commun 646-648
-
(1977)
J Chem Soc Chem Commun
, pp. 646-648
-
-
Stöckigt, J.1
Zenk, M.H.2
-
32
-
-
0036208023
-
Bioreactor production of camptothecin by hairy root cultures of Ophiorrhiza pumila
-
Sudo H, Yamakawa T, Yamazaki M, Aimi N, Saito K (2002) Bioreactor production of camptothecin by hairy root cultures of Ophiorrhiza pumila. Biotechnol Lett 24: 359-363
-
(2002)
Biotechnol Lett
, vol.24
, pp. 359-363
-
-
Sudo, H.1
Yamakawa, T.2
Yamazaki, M.3
Aimi, N.4
Saito, K.5
-
33
-
-
0000483862
-
Mechanism for iridane skeleton formation in the biosynthesis of secologanin and indole alkaloids in Lonicera tatarica, Catharanthus roseus and suspension cultures of Rauwolfia serpentina
-
Uesato S, Kanomi S, Iida A, Inouye H, Zenk MH (1986) Mechanism for iridane skeleton formation in the biosynthesis of secologanin and indole alkaloids in Lonicera tatarica, Catharanthus roseus and suspension cultures of Rauwolfia serpentina. Phytochemistry 25: 839-842
-
(1986)
Phytochemistry
, vol.25
, pp. 839-842
-
-
Uesato, S.1
Kanomi, S.2
Iida, A.3
Inouye, H.4
Zenk, M.H.5
-
34
-
-
0002510225
-
Monoterpene biosynthesis
-
DE Cane, ed, Elsevier Science Ltd., Amsterdam
-
Wise ML, Croteau R (1999) Monoterpene biosynthesis. In DE Cane, ed, Comprehensive Natural Product Chemistry, Vol 2. Elsevier Science Ltd., Amsterdam, pp 97-153
-
(1999)
Comprehensive Natural Product Chemistry
, vol.2
, pp. 97-153
-
-
Wise, M.L.1
Croteau, R.2
-
35
-
-
0037657891
-
Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: Cloning, characterization and differential expression in tissues and by stress compounds
-
Yamazaki Y, Sudo H, Yamazaki M, Aimi N, Saito K (2003a) Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: cloning, characterization and differential expression in tissues and by stress compounds. Plant Cell Physiol 44: 395-403
-
(2003)
Plant Cell Physiol
, vol.44
, pp. 395-403
-
-
Yamazaki, Y.1
Sudo, H.2
Yamazaki, M.3
Aimi, N.4
Saito, K.5
-
36
-
-
0037309409
-
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants
-
Yamazaki Y, Urano A, Sudo H, Kitajima M, Takayama H, Yamazaki M, Aimi N, Saito K (2003b) Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants. Phytochemistry 62: 461-470
-
(2003)
Phytochemistry
, vol.62
, pp. 461-470
-
-
Yamazaki, Y.1
Urano, A.2
Sudo, H.3
Kitajima, M.4
Takayama, H.5
Yamazaki, M.6
Aimi, N.7
Saito, K.8
|