Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration

Journal of Cell Biology

Volumn 142, Issue 1, 1998, Pages 117-127

  Martìn Padura, Inés ^a   Lostaglio, Susan ^a   Schneemann, Markus ^b   Williams, Lisa ^b   Romano, Maria ^a   Fruscella, Paolo ^a   Panzeri, Carla ^c   Stoppacciaro, Antonella ^d   Ruco, Luigi ^d   Villa, Antonello ^c   Simmons, David ^b   Dejana, Elisabetta ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF MILAN   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Endothelium; Epithelium; Inflammation; Monocyte tight junctions

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN SUBCLASS;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; ENDOTHELIUM CELL; EPITHELIUM CELL; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIGHT JUNCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS; BASE SEQUENCE; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE; CELL MOVEMENT; CLONING, MOLECULAR; COS CELLS; DNA, COMPLEMENTARY; ENDOTHELIUM; EPITHELIAL CELLS; IMMUNOGLOBULINS; MALE; MICE; MOLECULAR SEQUENCE DATA; MONOCYTES; RATS; RATS, INBRED LEW; SKIN; TIGHT JUNCTIONS; TRANSFECTION;

EID: 2642614521     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.1.117     Document Type: Article

References (60)

1. Allavena, P., C. Paganin, I. Martin-Padura, G. Peri, M. Gaboli, E. Dejana, P.C. Marchisio, and A. Mantovani. 1991. Molecules and structures involved in the adhesion of natural killer cells to vascular entothelium. J. Exp. Med. 173:439-448.
2. Anderson, A.O., and S. Shaw. 1993. T cell adhesion to endothelium: the FRC conduit system and other anatomic and molecular features which facilitate the adhesion cascade in lymph node. Semin. Immunol. 5:271-282.
3. Anderson, J.M., M.S. Balda, and A.S. Fanning. 1993. The structure and regulation of tight junctions. Curr. Opin. Cell Biol. 5:772-776.
4. Anderson, J.M. and C.M. Van Itallie. 1995. Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol. 269: G465-G475.
5. Ayalon, O., H. Sabanai, M.-G. Lampugnani, E. Dejana, and B. Geiger. 1994. Spatial and temporal relationships between cadherins and PE-CAM-1 in cell-cell junctions of human endothelial cells. J. Cell Biol. 126: 247-258.
6. Balda, M.S., J.A. Whitney, C. Flores, S. Gonzalez, M. Cereijido, and K. Matter. 1996. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134:1031-1049.
7. Bogen, S., J. Pak, M. Garifallou, X. Deng, and W.A. Muller. 1994. Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo. J. Exp. Med. 179:1059-1064.
8. Bork, P., L. Holm, and C. Sander. 1994. The immunoglobulin fold: structural classification, sequence patterns and common core. J. Mol. Biol. 242:309-320.
9. Breier, G., F. Breviario, L. Caveda, R. Berthier, U. Schnurch, D. Gotsch, D. Vestweber, W. Risau, and E. Dejana. 1996. Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood. 87:630-642.
10. Breviario, F., L. Caveda, M. Corada, I. Martin-Padura, P. Navarro, J. Golay, M. Introna, D. Gulino, M.G. Lampugnani, and E. Dejana. 1995. Functional properties of human vascular endothelial cadherin (7B4/cadherin-5) an endothelial specific cadherin. Arterioscler. Thromb. Vasc. Biol. 15:1229-1239.
11. Citi, S. 1993. The molecular organization of tight junctions. J. Cell Biol. 121: 485-489.
12. Citi, S., H. Sabanay, R. Jakes, B. Geiger, and J. Kendrick-Jones. 1988. Cingulin, a new peripheral component of tight junctions. Nature. 333:272-276.
13. Citi, S., H. Sabanay, J. Kendrick-Jones, and B. Geiger. 1989. Cingulin: characterization and localization. J. Cell Sci. 93:107-122.
14. Colotta, F., G. Peri, A. Villa, and A. Mantovani. 1984. Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells.I. Effectors belong to the monocyte-macrophage lineage. J. Immunol. 132:936-942.
15. Dejana, E. 1997. Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis. J. Clin. Invest. 98:1949-1953.
16. Dejana, E., M. Corada, and M.-G. Lampugnani. 1995. Endothelial cell-to-cell junctions. FASEB J. 9:910-918.
17. Dong, Q.G., S. Bernasconi, S. Lostaglio, R. Wainstok de Calmanovic, I. Martin-Padura, F. Breviario, A. Mantovani, and A. Vecchi. 1997. A general strategy for isolation of endothelial cells from murine tissues: characterization of two endothelial cell lines obtained from murine lung and subcutaneous sponge implants. Arterioscler. Thromb. Vasc. Biol. 17: 1599-1904.
18. Edwards, J.C., A.D. Sedgwick, and D.A. Willoughby. 1981. The formation of a structure with features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system. J. Pathol. 134:147-156.
19. Fawcett, J., C.L. Holness, L.A. Needham, H. Turley, K.C. Gatter, D.Y. Mason, and D.L. Simmons. 1992. Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature. 360:481-484.
20. Fawcett, J., C. Buckley, C.L. Holness, I.N. Bird, J.H. Spragg, J. Saunders, A. Harris, and D.L. Simmons. 1995. Mapping and homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts. J. Cell Biol. 128: 1229-1241.
21. Furuse, M., T. Hirase, M. Itoh, A. Nagafuchi, S. Yonemura, and S. Tsukita. 1993. Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123:1777-1788.
22. Furuse, M., M. Itoh, T. Hirase, A. Nagasuchi, S. Yonemura, and S. Tsukita. 1994. Direct association of occludin with ZO-1 and ils possible involvement in the localization of occludin at tight junction. J. Cell Biol. 127: 1617-1626.
23. Fusening, N.E., D. Breitkreutz, R.T. Dzrlieva, P. Boukamp, E. Hezmann, A. Bohnert, J. Pohlmann, C. Rausch, S. Schutz, and J. Hornung. 1982. Epidermal cell differentiation and malignant transformation in culture. Cancer Forum. 6:209-240.
24. Garlanda, C., R. Berthier, J. Garin, A. Stoppacciaro, D. Vittet, D. Goulino, C. Matteucci, A. Mantovani, A. Vecchi, and E. Dejana. 1997. Characterization of MEC 14, a new monoclonal antibody recognizing mouse CD34: a useful reagent for identification and characterization of blood vessels and hematopoietic precursors. Eur. J. Cell Biol. 73:368-377.
25. Garlanda, C., C. Parravicini, M. Sironi, M. De Rossi, R. Wainstok de Calmanovici, F. Carozzi, F. Bussolino, F. Colotta, A. Mantovani, and A. Vecchi. 1994. Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle T: implications for the pathogenesis of opportunistic vascular tumors. Proc. Natl. Acad. Sci. USA. 91:7291-7295.
26. Geiger, B., and O. Ayalon. 1992. Cadherins. Ann. Rev. Cell Biol. 8:307-332.
27. Girard, J.-P., and T.A. Springer. 1995. High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol. Today. 16: 449-457.
28. Gumbiner, B.M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
29. Harpaz, Y., and C. Chothia. 1994. Many of the immunoglobulins superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains. J. Mol. Biol. 238:528-539.
30. Heath, J.K., S.J. White, C.N. Johnstone, B. Catimel, R.J. Simpson, R.L. Moritz, G.-F. Tu, H. Ji, R.H. Whitehead, L.C. Groenen, et al. 1997. The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. Proc. Natl. Acad. Sci. USA. 94: 469-474.
31. Hulksen, J., J. Berhens, and W. Birchmeier. 1994. Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol. 6:711-716.
32. Imhof, B., and D. Dunon. 1995. Leukocyte migration and adhesion. Adv. Immunol. 58:345-416.
33. Kemler, R. 1993. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9:317-321.
34. Keon, B.H., S.S. Schafer, C. Kuhn, C. Grund, and W.W. Franke. 1996. Symplekin, a novel type of light junction plaque protein. J. Cell Biol. 134: 1003-1018.
35. Klymkowsky, M.W., and B. Parr. 1995. The body language of the cells: the intimate connection between cell adhesion and behavior. Cell. 83:5-8.
36. Lampugnani, M.G., M. Resnati, M. Raiteri, R. Pigott, A. Pisacane, G. Houen, and L. Ruco. 1992. A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J. Cell Biol. 118:1511-1522.
37. Martin-Padura, I., G. Bazzoni, A. Zanetti, S. Bernasconi, M.J. Elices, A. Mantovani, and E. Dejana. 1994. A novel mechanism of colon carcinoma cell adhesion to the endothelium triggered by β1 integrin chain. J. Biol. Chem. 269:6124-6132.
38. Muller, W.A., S.A. Weigl, X. Deng, and D.M. Phillips. 1993. PECAM-1 is required for transendothelial migration of leukocytes. J. Exp. Med. 178: 449-460.
39. Navarro, P., L. Caveda, F. Breviario, I. Mandoteanu, M.G. Lampugnani, and E. Dejana. 1995. Catenin-dependent and -independent functions of vascular endothelial cadherin. J. Biol. Chem. 270:30965-30972.
40. Navarro, P., L. Ruco, and E. Dejana. 1998. Differential localization of VE- and N-cadherin in human endolhelial cells. VE-cadherin competes with N-cadherin for junctional localization. J. Cell Biol. 140:1475-1484.
41. Parham, P. 1985. In Hanbook of Experimental Immunology in Four Volumes: Immunochemistry. Vol. 14. D.M. Weir, editor. Blackwell Scientific Publications, Oxford. 1-23.
42. Perego, C., A. Bulbarelli, R. Longhi, M. Caimi, A. Villa, M.J. Caplan, and G. Pietrini. 1997. Sorting of two polytopic proteins, the gamma-aminobutyric acid and betaine transporters, in polarized epithelial cells. J. Biol. Chem. 272:6584-6592.
43. Rival, Y., A. Del Maschio, M.-J. Rabiet, E. Dejana, and A. Duperray. 1996. Inhibition of platelet endothelial cell adhesion molecule-1 synthesis and leukocyte transmigration in endothelial cells by the combined action of TNF-α and IFN-γ. J. Immunol. 157:1233-1241.
44. Romano, M., R. Faggioni, M. Sironi, S. Sacco, B. Echtenacher, E. Di Santo, M. Salmona, and P. Ghezzi. 1997. Carrageenan-induced acute inflammation in the mouse air pouch synovial model. Role of tumor necrosis factor. Mediat. Inflamm. 6:1-7.
45. Rubin, L.L. 1992. Endothelial cells: adhesion and tight junctions. Curr. Opin. Cell Biol. 4:830-833.
46. Seed, B. 1987. An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature. 329:840-842.
47. Seed, B., and A. Aruffo. 1987. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA. 84:3365-3369.
48. Simionescu, N., and N.Z. Simionescu. 1991. Endothelial transport macromolecule: transcytosis and endocytosis. Cell Biol. Rev. 25:5-80.
49. Simmons, D., M.W. Makgoba, and B. Seed. 1988. ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature. 331:624-627.
50. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-314.
51. Stevenson, B.R., J.D. Siciliano, M.S. Mooseker, and D.A. Goodenough. 1986. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103:755-766.
52. Takeichi, M. 1993. Cadherin in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol. 5:806-811.
53. Van Damme, J., P. Proost, J.P. Lanaerst, and G. Opdenakker. 1997. Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family. J. Exp. Med. 176:59-65.
54. Van Itallie, C.M., and J.M. Anderson. 1997. Occludin confers adhesiveness when expressed in fibroblasts. J. Cell Sci. 110:1113-1121.
55. Vaporciyan, A.A., H.M. DeLisser, H.-C. Yan, I.I. Mendiguren, S.R. Thom, M.L. Jones, P.A. Ward, and S.M. Albelda. 1993. Involvement of plalelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science. 262:1580-1582.
56. Vecchi, A., C. Garlanda, M.-G. Lampugnani, M. Resnati, C. Matteucci, A. Stoppacciaro, H. Schnurch, W. Risau, L. Ruco, A. Mantovani, and E. Dejana. 1994. Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium. Eur. J. Cell Biol. 63:247-254.
57. Villa, A., P. Podini, M.C. Panzeri, H.D. Soling, P. Volpe, and J. Meldolesi. 1993. The endoplasmic-sarcoplasmic reticulum of smooth muscle: immunocytochemistry of vas deferens fibers reveals specialized subcompartments differently equipped for the control of Ca++ homeostasis. J. Cell Biol. 121:1041-1051.
58. Walport, M.J., K.A. Davies, B.J. Morley, and M. Botto. 1997.Complement deficiency and autoimmunity. Ann. NY Acad. Sci. 815:267-281.
59. Wang, J.M., A. Sica, G. Peri, S. Walter, I.M. Padura, P. Libby, M. Ceska, I. Lindley, F. Colotta, and A. Mantovani. 1991. Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells. Arterioscler. Thromb. 11:1166-1174.
60. Zocchi, M.R., E. Ferrero, B.E. Leone, P. Rovere, E. Bianchi, E. Toninelli, and R. Pardi. 1996. CD 31/PECAM-1 driven chemokine-independent transmigration of human T lymphocytes. Eur. J. Immunol. 26:759-767.