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Volumn 9, Issue , 2007, Pages

Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; MAP KINASE KINASE KINASE 7; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; UNCLASSIFIED DRUG;

EID: 34347392053     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2215     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • 10.1038/nature01661 12748655
    • Firestein GS Evolving concepts of rheumatoid arthritis Nature 2003 423 356-361 10.1038/nature01661 12748655
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 2
    • 18844430825 scopus 로고    scopus 로고
    • The fibroblast-like synovial cell in rheumatoid arthritis: A key player in inflammation and joint destruction
    • 10.1016/j.clim.2004.12.009 15885632
    • Mor A Abramson SB Pillinger MH The fibroblast-like synovial cell in rheumatoid arthritis: A key player in inflammation and joint destruction Clin Immunol 2005 115 118-128 10.1016/j.clim.2004.12.009 15885632
    • (2005) Clin Immunol , vol.115 , pp. 118-128
    • Mor, A.1    Abramson, S.B.2    Pillinger, M.H.3
  • 3
    • 0025673956 scopus 로고
    • Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes
    • 329810 2174906
    • Alvaro-Gracia JM Zvaifler NJ Firestein GS Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes J Clin Invest 1990 86 1790-1798 329810 2174906
    • (1990) J Clin Invest , vol.86 , pp. 1790-1798
    • Alvaro-Gracia, J.M.1    Zvaifler, N.J.2    Firestein, G.S.3
  • 4
    • 0025847243 scopus 로고
    • Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha
    • 2026869
    • Alvaro-Gracia JM Zvaifler NJ Brown CB Kaushansky K Firestein GS Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha J Immunol 1991 146 3365-3371 2026869
    • (1991) J Immunol , vol.146 , pp. 3365-3371
    • Alvaro-Gracia, J.M.1    Zvaifler, N.J.2    Brown, C.B.3    Kaushansky, K.4    Firestein, G.S.5
  • 5
    • 0036240838 scopus 로고    scopus 로고
    • Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors
    • 128926 12010565 10.1186/ar401
    • Vincenti MP Brinckerhoff CE Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors Arthritis Res 2002 4 157-164 128926 12010565 10.1186/ar401
    • (2002) Arthritis Res , vol.4 , pp. 157-164
    • Vincenti, M.P.1    Brinckerhoff, C.E.2
  • 6
    • 0142212329 scopus 로고    scopus 로고
    • Regulation of matrix Metalloproteinases: An overview
    • 10.1023/A:1026028303196 14619979
    • Chakraborti S Mandal M Das S Mandal A Chakraborti T Regulation of matrix metalloproteinases: An overview Mol Cell Biochem 2003 253 269-285 10.1023/A:1026028303196 14619979
    • (2003) Mol Cell Biochem , vol.253 , pp. 269-285
    • Chakraborti, S.1    Mandal, M.2    Das, S.3    Mandal, A.4    Chakraborti, T.5
  • 7
    • 32844461713 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase (MMP) gene expression by protein kinases
    • 10.2741/1873 16368506
    • Reuben PM Cheung HS Regulation of matrix metalloproteinase (MMP) gene expression by protein kinases Front Biosci 2006 11 1199-1215 10.2741/ 1873 16368506
    • (2006) Front Biosci , vol.11 , pp. 1199-1215
    • Reuben, P.M.1    Cheung, H.S.2
  • 8
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • 11274345
    • Kyriakis JM Avruch J Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation Physiol Rev 2001 81 807-869 11274345
    • (2001) Physiol Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 9
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • 10.1126/science.1072682 12471242
    • Johnson GL Lapadat R Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 2002 298 1911-1912 10.1126/ science.1072682 12471242
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 10
    • 0142156224 scopus 로고    scopus 로고
    • Signal transduction networks in rheumatoid arthritis
    • 1766749 14532158
    • Hammaker D Sweeney S Firestein GS Signal transduction networks in rheumatoid arthritis Ann Rheum Dis 2003 62 Suppl 2 ii86-89 1766749 14532158
    • (2003) Ann Rheum Dis , vol.62 , Issue.SUPPL.
    • Hammaker, D.1    Sweeney, S.2    Firestein, G.S.3
  • 11
    • 0031976639 scopus 로고    scopus 로고
    • Antisense oligonucleotides targeting c-fos mRNA inhibit rheumatoid synovial fibroblast proliferation
    • 1752536 9613344
    • Morita Y Kashihara N Yamamura M Okamoto H Harada S Kawashima M Makino H Antisense oligonucleotides targeting c-fos mRNA inhibit rheumatoid synovial fibroblast proliferation Ann Rheum Dis 1998 57 122-124 1752536 9613344
    • (1998) Ann Rheum Dis , vol.57 , pp. 122-124
    • Morita, Y.1    Kashihara, N.2    Yamamura, M.3    Okamoto, H.4    Harada, S.5    Kawashima, M.6    Makino, H.7
  • 12
    • 2342610548 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor up-regulates the expression of interleukin-8 messenger RNA in synovial fibroblasts of rheumatoid arthritis patients: Common transcriptional regulatory mechanism between interleukin-8 and interleukin-1beta
    • 10.1002/art.20190 15146413
    • Onodera S Nishihira J Koyama Y Majima T Aoki Y Ichiyama H Ishibashi T Minami A Macrophage migration inhibitory factor up-regulates the expression of interleukin-8 messenger RNA in synovial fibroblasts of rheumatoid arthritis patients: Common transcriptional regulatory mechanism between interleukin-8 and interleukin-1beta Arthritis Rheum 2004 50 1437-1447 10.1002/art.20190 15146413
    • (2004) Arthritis Rheum , vol.50 , pp. 1437-1447
    • Onodera, S.1    Nishihira, J.2    Koyama, Y.3    Majima, T.4    Aoki, Y.5    Ichiyama, H.6    Ishibashi, T.7    Minami, A.8
  • 13
    • 0037042382 scopus 로고    scopus 로고
    • An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression
    • 10.1016/S0167-4889(02)00195-7 12031798
    • Shin M Yan C Boyd D An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression Biochim Biophys Acta 2002 1589 311-316 10.1016/S0167-4889(02)00195-7 12031798
    • (2002) Biochim Biophys Acta , vol.1589 , pp. 311-316
    • Shin, M.1    Yan, C.2    Boyd, D.3
  • 14
    • 0032428729 scopus 로고    scopus 로고
    • AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis
    • 9892501
    • Han Z Boyle DL Manning AM Firestein GS AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis Autoimmunity 1998 28 197-208 9892501
    • (1998) Autoimmunity , vol.28 , pp. 197-208
    • Han, Z.1    Boyle, D.L.2    Manning, A.M.3    Firestein, G.S.4
  • 16
    • 0034931503 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
    • 209341 11435459 10.1172/JCI200112466
    • Han Z Boyle DL Chang L Bennett B Karin M Yang L Manning AM Firestein GS c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis J Clin Invest 2001 108 73-81 209341 11435459 10.1172/JCI200112466
    • (2001) J Clin Invest , vol.108 , pp. 73-81
    • Han, Z.1    Boyle, D.L.2    Chang, L.3    Bennett, B.4    Karin, M.5    Yang, L.6    Manning, A.M.7    Firestein, G.S.8
  • 17
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • 10.1016/S0092-8674(00)00116-1 11057897
    • Davis RJ Signal transduction by the JNK group of MAP kinases Cell 2000 103 239-252 10.1016/S0092-8674(00)00116-1 11057897
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 18
    • 0141676444 scopus 로고    scopus 로고
    • Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK
    • 10.1002/art.11228 13130464
    • Sundarrajan M Boyle DL Chabaud-Riou M Hammaker D Firestein GS Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK Arthritis Rheum 2003 48 2450-2460 10.1002/ art.11228 13130464
    • (2003) Arthritis Rheum , vol.48 , pp. 2450-2460
    • Sundarrajan, M.1    Boyle, D.L.2    Chabaud-Riou, M.3    Hammaker, D.4    Firestein, G.S.5
  • 19
    • 33745925590 scopus 로고    scopus 로고
    • Regulation of JNK by MKK-7 in fibroblast-like synoviocytes
    • 10.1002/art.21919 16802349
    • Inoue T Hammaker D Boyle DL Firestein GS Regulation of JNK by MKK-7 in fibroblast-like synoviocytes Arthritis Rheum 2006 54 2127-2135 10.1002/ art.21919 16802349
    • (2006) Arthritis Rheum , vol.54 , pp. 2127-2135
    • Inoue, T.1    Hammaker, D.2    Boyle, D.L.3    Firestein, G.S.4
  • 20
    • 1642444091 scopus 로고    scopus 로고
    • Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis
    • 14734742
    • Hammaker DR Boyle DL Chabaud-Riou M Firestein GS Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis J Immunol 2004 172 1612-1618 14734742
    • (2004) J Immunol , vol.172 , pp. 1612-1618
    • Hammaker, D.R.1    Boyle, D.L.2    Chabaud-Riou, M.3    Firestein, G.S.4
  • 21
    • 0346496017 scopus 로고    scopus 로고
    • Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
    • 10.1038/ni1014 14661019
    • Huang Q Yang J Lin Y Walker C Cheng J Liu ZG Su B Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3 Nat Immunol 2004 5 98-103 10.1038/ni1014 14661019
    • (2004) Nat Immunol , vol.5 , pp. 98-103
    • Huang, Q.1    Yang, J.2    Lin, Y.3    Walker, C.4    Cheng, J.5    Liu, Z.G.6    Su, B.7
  • 22
    • 1042268043 scopus 로고    scopus 로고
    • MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts
    • 10.1002/jcp.10457 14978743
    • Kesavan K Lobel-Rice K Sun W Lapadat R Webb S Johnson GL Garrington TP MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts J Cell Physiol 2004 199 140-148 10.1002/jcp.10457 14978743
    • (2004) J Cell Physiol , vol.199 , pp. 140-148
    • Kesavan, K.1    Lobel-Rice, K.2    Sun, W.3    Lapadat, R.4    Webb, S.5    Johnson, G.L.6    Garrington, T.P.7
  • 24
    • 2442622585 scopus 로고    scopus 로고
    • Quantitative biomarker analysis of synovial gene expression by real-time PCR
    • 333415 14680510 10.1186/ar1004
    • Boyle DL Rosengren S Bugbee W Kavanaugh A Firestein GS Quantitative biomarker analysis of synovial gene expression by real-time PCR Arthritis Res Ther 2003 5 R352-360 333415 14680510 10.1186/ar1004
    • (2003) Arthritis Res Ther , vol.5
    • Boyle, D.L.1    Rosengren, S.2    Bugbee, W.3    Kavanaugh, A.4    Firestein, G.S.5
  • 25
    • 0026033431 scopus 로고
    • Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts
    • 10.1084/jem.173.3.569 1997647
    • Bucala R Ritchlin C Winchester R Cerami A Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts J Exp Med 1991 173 569-574 10.1084/jem.173.3.569 1997647
    • (1991) J Exp Med , vol.173 , pp. 569-574
    • Bucala, R.1    Ritchlin, C.2    Winchester, R.3    Cerami, A.4
  • 26
    • 0036143713 scopus 로고    scopus 로고
    • Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2
    • 133545 11784851
    • Chadee DN Yuasa T Kyriakis JM Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2 Mol Cell Biol 2002 22 737-749 133545 11784851
    • (2002) Mol Cell Biol , vol.22 , pp. 737-749
    • Chadee, D.N.1    Yuasa, T.2    Kyriakis, J.M.3
  • 27
    • 0028148921 scopus 로고
    • Collagenase and stromelysin expression in rheumatoid synovium and cartilage: Comment on the article by Wolfe et al
    • 10.1002/art.1780371225 7986235
    • Ritchlin C Haas-Smith S Collagenase and stromelysin expression in rheumatoid synovium and cartilage: Comment on the article by Wolfe et al Arthritis Rheum 1994 37 1831-1833 10.1002/art.1780371225 7986235
    • (1994) Arthritis Rheum , vol.37 , pp. 1831-1833
    • Ritchlin, C.1    Haas-Smith, S.2
  • 28
    • 21344474327 scopus 로고    scopus 로고
    • From JNK to pay dirt: Jun kinases, their biochemistry, physiology and clinical importance
    • 16036612
    • Karin M Gallagher E From JNK to pay dirt: Jun kinases, their biochemistry, physiology and clinical importance IUBMB Life 2005 57 283-295 16036612
    • (2005) IUBMB Life , vol.57 , pp. 283-295
    • Karin, M.1    Gallagher, E.2
  • 29
    • 0346890213 scopus 로고    scopus 로고
    • Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway
    • 10.1074/jbc.M204934200 12351623
    • Chen W White MA Cobb MH Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway J Biol Chem 2002 277 4910-49110 10.1074/ jbc.M204934200 12351623
    • (2002) J Biol Chem , vol.277 , pp. 49105-49110
    • Chen, W.1    White, M.A.2    Cobb, M.H.3
  • 30
    • 0346039151 scopus 로고    scopus 로고
    • MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis
    • 14627958
    • Zhang L Deng M Kao CW Kao WW Xia Y MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis Mol Vis 2003 9 584-593 14627958
    • (2003) Mol Vis , vol.9 , pp. 584-593
    • Zhang, L.1    Deng, M.2    Kao, C.W.3    Kao, W.W.4    Xia, Y.5
  • 31
    • 0034625170 scopus 로고    scopus 로고
    • MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
    • 25813 10805784 10.1073/pnas.97.10.5243
    • Xia Y Makris C Su B Li E Yang J Nemerow GR Karin M MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration Proc Natl Acad Sci USA 2000 97 5243-5248 25813 10805784 10.1073/ pnas.97.10.5243
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5243-5248
    • Xia, Y.1    Makris, C.2    Su, B.3    Li, E.4    Yang, J.5    Nemerow, G.R.6    Karin, M.7
  • 32
    • 0034050739 scopus 로고    scopus 로고
    • Mekk3 is essential for early embryonic cardiovascular development
    • 10.1038/73550 10700190
    • Yang J Boerm M McCarty M Bucana C Fidler IJ Zhuang Y Su B Mekk3 is essential for early embryonic cardiovascular development Nat Genet 2000 24 309-313 10.1038/73550 10700190
    • (2000) Nat Genet , vol.24 , pp. 309-313
    • Yang, J.1    Boerm, M.2    McCarty, M.3    Bucana, C.4    Fidler, I.J.5    Zhuang, Y.6    Su, B.7
  • 33
    • 0034061264 scopus 로고    scopus 로고
    • Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation
    • 85399 10713157 10.1128/MCB.20.7.2334-2342.2000
    • Cheng J Yang J Xia Y Karin M Su B Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation Mol Cell Biol 2000 20 2334-2342 85399 10713157 10.1128/MCB.20.7.2334-2342.2000
    • (2000) Mol Cell Biol , vol.20 , pp. 2334-2342
    • Cheng, J.1    Yang, J.2    Xia, Y.3    Karin, M.4    Su, B.5
  • 34
    • 0034675925 scopus 로고    scopus 로고
    • MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells
    • 314024 11032806 10.1093/emboj/19.20.5387
    • Garrington TP Ishizuka T Papst PJ Chayama K Webb S Yujiri T Sun W Sather S Russell DM Gibson SB MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells EMBO J 2000 19 5387-5395 314024 11032806 10.1093/ emboj/19.20.5387
    • (2000) EMBO J , vol.19 , pp. 5387-5395
    • Garrington, T.P.1    Ishizuka, T.2    Papst, P.J.3    Chayama, K.4    Webb, S.5    Yujiri, T.6    Sun, W.7    Sather, S.8    Russell, D.M.9    Gibson, S.B.10
  • 35
    • 0035805552 scopus 로고    scopus 로고
    • MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression
    • 10.1074/jbc.M010134200 11278622
    • Su B Cheng J Yang J Guo Z MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression J Biol Chem 2001 276 14784-14790 10.1074/jbc.M010134200 11278622
    • (2001) J Biol Chem , vol.276 , pp. 14784-14790
    • Su, B.1    Cheng, J.2    Yang, J.3    Guo, Z.4
  • 37
    • 0036788753 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
    • 139807 12242293 10.1128/MCB.22.20.7158-7167.2002
    • Jiang Z Ninomiya-Tsuji J Qian Y Matsumoto K Li X Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol Mol Cell Biol 2002 22 7158-7167 139807 12242293 10.1128/ MCB.22.20.7158-7167.2002
    • (2002) Mol Cell Biol , vol.22 , pp. 7158-7167
    • Jiang, Z.1    Ninomiya-Tsuji, J.2    Qian, Y.3    Matsumoto, K.4    Li, X.5
  • 38
    • 33745194935 scopus 로고    scopus 로고
    • Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
    • 10.1210/me.2005-0301 16543409
    • Frobose H Ronn SG Heding PE Mendoza H Cohen P Mandrup-Poulsen T Billestrup N Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex Mol Endocrinol 2006 20 1587-1596 10.1210/me.2005-0301 16543409
    • (2006) Mol Endocrinol , vol.20 , pp. 1587-1596
    • Frobose, H.1    Ronn, S.G.2    Heding, P.E.3    Mendoza, H.4    Cohen, P.5    Mandrup-Poulsen, T.6    Billestrup, N.7
  • 39
    • 14844295421 scopus 로고    scopus 로고
    • Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2
    • 10.1074/jbc.M407537200 15590691
    • Singhirunnusorn P Suzuki S Kawasaki N Saiki I Sakurai H Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2 J Biol Chem 2005 280 7359-7368 10.1074/jbc.M407537200 15590691
    • (2005) J Biol Chem , vol.280 , pp. 7359-7368
    • Singhirunnusorn, P.1    Suzuki, S.2    Kawasaki, N.3    Saiki, I.4    Sakurai, H.5
  • 40
    • 0346243941 scopus 로고    scopus 로고
    • Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
    • 291846 14633987 10.1093/emboj/cdg605
    • Ishitani T Takaesu G Ninomiya-Tsuji J Shibuya H Gaynor RB Matsumoto K Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling EMBO J 2003 22 6277-6288 291846 14633987 10.1093/emboj/cdg605
    • (2003) EMBO J , vol.22 , pp. 6277-6288
    • Ishitani, T.1    Takaesu, G.2    Ninomiya-Tsuji, J.3    Shibuya, H.4    Gaynor, R.B.5    Matsumoto, K.6
  • 41
    • 1542314841 scopus 로고    scopus 로고
    • TAB3, a new binding partner of the protein kinase TAK1
    • 1223947 14670075 10.1042/BJ20031794
    • Cheung PC Nebreda AR Cohen P TAB3, a new binding partner of the protein kinase TAK1 Biochem J 2004 378 27-34 1223947 14670075 10.1042/BJ20031794
    • (2004) Biochem J , vol.378 , pp. 27-34
    • Cheung, P.C.1    Nebreda, A.R.2    Cohen, P.3
  • 42
    • 0034629146 scopus 로고    scopus 로고
    • TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
    • 10.1074/jbc.275.10.7359 10702308
    • Kishimoto K Matsumoto K Ninomiya-Tsuji J TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop J Biol Chem 2000 275 7359-7364 10.1074/jbc.275.10.7359 10702308
    • (2000) J Biol Chem , vol.275 , pp. 7359-7364
    • Kishimoto, K.1    Matsumoto, K.2    Ninomiya-Tsuji, J.3
  • 43
    • 0033580466 scopus 로고    scopus 로고
    • The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
    • 10.1038/18465 10094049
    • Ninomiya-Tsuji J Kishimoto K Hiyama A Inoue J Cao Z Matsumoto K The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway Nature 1999 398 252-256 10.1038/ 18465 10094049
    • (1999) Nature , vol.398 , pp. 252-256
    • Ninomiya-Tsuji, J.1    Kishimoto, K.2    Hiyama, A.3    Inoue, J.4    Cao, Z.5    Matsumoto, K.6
  • 45
    • 0036023042 scopus 로고    scopus 로고
    • TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB
    • 12296995
    • Lee SW Han SI Kim HH Lee ZH TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB J Biochem Mol Biol 2002 35 371-376 12296995
    • (2002) J Biochem Mol Biol , vol.35 , pp. 371-376
    • Lee, S.W.1    Han, S.I.2    Kim, H.H.3    Lee, Z.H.4
  • 46
    • 0037422858 scopus 로고    scopus 로고
    • TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway
    • 10.1016/S0022-2836(02)01404-3 12547194
    • Takaesu G Surabhi RM Park KJ Ninomiya-Tsuji J Matsumoto K Gaynor RB TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway J Mol Biol 2003 326 105-115 10.1016/S0022-2836(02)01404-3 12547194
    • (2003) J Mol Biol , vol.326 , pp. 105-115
    • Takaesu, G.1    Surabhi, R.M.2    Park, K.J.3    Ninomiya-Tsuji, J.4    Matsumoto, K.5    Gaynor, R.B.6
  • 47
    • 23044483249 scopus 로고    scopus 로고
    • Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes
    • 10.1074/jbc.M411657200 15837794
    • Thiefes A Wolter S Mushinski JF Hoffmann E Dittrich-Breiholz O Graue N Dorrie A Schneider H Wirth D Luckow B Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes J Biol Chem 2005 280 27728-27741 10.1074/jbc.M411657200 15837794
    • (2005) J Biol Chem , vol.280 , pp. 27728-27741
    • Thiefes, A.1    Wolter, S.2    Mushinski, J.F.3    Hoffmann, E.4    Dittrich-Breiholz, O.5    Graue, N.6    Dorrie, A.7    Schneider, H.8    Wirth, D.9    Luckow, B.10
  • 48
    • 22844440947 scopus 로고    scopus 로고
    • Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors
    • 10.1074/jbc.M503368200 15911626
    • Hoffmann A Preobrazhenska O Wodarczyk C Medler Y Winkel A Shahab S Huylebroeck D Gross G Verschueren K Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors J Biol Chem 2005 280 27271-27283 10.1074/jbc.M503368200 15911626
    • (2005) J Biol Chem , vol.280 , pp. 27271-27283
    • Hoffmann, A.1    Preobrazhenska, O.2    Wodarczyk, C.3    Medler, Y.4    Winkel, A.5    Shahab, S.6    Huylebroeck, D.7    Gross, G.8    Verschueren, K.9


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