Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells

Diabetes

Volumn 57, Issue 6, 2008, Pages 1651-1658

  Liu, Xuebin ^a   Mameza, Marie G ^a   Lee, Yun Sang ^a   Eseonu, Chikezie I ^a,b   Yu, Cheng Rong ^a   Derwent, Jennifer J Kang ^c   Egwuagu, Charles E ^a,d  

^a NATIONAL EYE INSTITUTE   (United States)

^b HARVARD COLLEGE   (United States)

^c Illinois Institute of Technology   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; SUPPRESSOR OF CYTOKINE SIGNALING PROTEIN 6; UNCLASSIFIED DRUG; SMALL INTERFERING RNA; SOCS3 PROTEIN, MOUSE; SOCS6 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL STRESS; CELL SURVIVAL; CHRONIC INFLAMMATION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; DISEASE COURSE; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INSULIN DEFICIENCY; INSULIN RESISTANCE; METABOLIC STRESS; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; RETINA; RETINA CELL; RETINA DEGENERATION; TRANSGENICS; UVEITIS; ANIMAL; C57BL MOUSE; CELL LINE; CYTOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENETIC TRANSFECTION; GENETICS; ORGAN CULTURE TECHNIQUE; PATHOPHYSIOLOGY; PHYSIOLOGY; PIGMENT EPITHELIUM; RETINA GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; INSULIN RESISTANCE; MICE; MICE, INBRED C57BL; ORGAN CULTURE TECHNIQUES; PIGMENT EPITHELIUM OF EYE; RATS; RETINA; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSFECTION;

EID: 48249098935     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db07-1761     Document Type: Article

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