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Volumn 46, Issue 12, 2005, Pages 4409-4416

Expression and activation of STAT3 in ischemia-induced retinopathy

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE;

EID: 33644806792     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-0632     Document Type: Article
Times cited : (37)

References (47)
  • 2
    • 0028929803 scopus 로고
    • Angiogenesls in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesls in cancer, vascular, rheumatoid and other disease. Nat Med. 1995;1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 3
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 1992;359:843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 4
    • 0033895534 scopus 로고    scopus 로고
    • Retinal and choroidal neovascularization
    • Campochiaro PA. Retinal and choroidal neovascularization. J Cell Physiol. 2000:184:301-310.
    • (2000) J Cell Physiol , vol.184 , pp. 301-310
    • Campochiaro, P.A.1
  • 5
    • 0042192111 scopus 로고    scopus 로고
    • Retinopathy of prematurity: Molecular pathology and therapeutic strategies
    • Mechoulam H, Pierce EA. Retinopathy of prematurity: molecular pathology and therapeutic strategies. Am J Pharmacogenomics. 2003;3:261-277.
    • (2003) Am J Pharmacogenomics , vol.3 , pp. 261-277
    • Mechoulam, H.1    Pierce, E.A.2
  • 6
    • 0031867565 scopus 로고    scopus 로고
    • Angiogenic factors in diabetic ocular disease: Mechanisms of today, therapies for tomorrow
    • Robinson GS, Aiello LP. Angiogenic factors in diabetic ocular disease: mechanisms of today, therapies for tomorrow. Int Ophthalmol Clinics. 1998;38:89-102.
    • (1998) Int Ophthalmol Clinics , vol.38 , pp. 89-102
    • Robinson, G.S.1    Aiello, L.P.2
  • 7
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
    • Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell. 1998;92:391-400.
    • (1998) Cell , vol.92 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalscha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 8
    • 0030824259 scopus 로고    scopus 로고
    • Vascular endothelial growth factor. 20th-century mechanisms, 21st-century therapies
    • Aiello LP. Vascular endothelial growth factor. 20th-century mechanisms, 21st-century therapies. Invest Ophthalmol Vis Sci. 1997;38:1647-1652.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 1647-1652
    • Aiello, L.P.1
  • 9
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem. 1998;273:30336-30343.
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3
  • 10
    • 0036411819 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3′-kinase mediates PKC delta phosphorylation: Role of PKC in angiogenesis
    • Gliki G, Wheeler-Jones C, Zachary I. Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3′-kinase mediates PKC delta phosphorylation: role of PKC in angiogenesis. Cell Biol Int. 2002;26:751-759.
    • (2002) Cell Biol Int , vol.26 , pp. 751-759
    • Gliki, G.1    Wheeler-Jones, C.2    Zachary, I.3
  • 11
    • 0030935260 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
    • Takeda K, Noguchi K, SW W, et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci USA. 1997;94:3801-3804.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3801-3804
    • Takeda, K.1    Noguchi, K.2    SW, W.3
  • 12
    • 0031024108 scopus 로고    scopus 로고
    • STAT signaling is active during early mammalian development
    • Duncan SA, Zhong Z, Wen ZL, Darnell JE. STAT signaling is active during early mammalian development. Dev Dyn. 1997;208:190-198.
    • (1997) Dev Dyn , vol.208 , pp. 190-198
    • Duncan, S.A.1    Zhong, Z.2    Wen, Z.L.3    Darnell, J.E.4
  • 13
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, Akira S. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol. 1998;161:4652-4660.
    • (1998) J Immunol , vol.161 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 14
    • 0037047360 scopus 로고    scopus 로고
    • STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration
    • Li W, Liang X, Kellendonk C, Poli V, Taub R. STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration. J Biol Chem. 2002;277:28411-28417.
    • (2002) J Biol Chem , vol.277 , pp. 28411-28417
    • Li, W.1    Liang, X.2    Kellendonk, C.3    Poli, V.4    Taub, R.5
  • 15
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res. 2002;8:945-954.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 17
    • 0028303977 scopus 로고
    • Molecular-cloning of Aprf, a novel IFN-stimulated gene factor-3 p91-related transcription factor involved in the Gp130-mediated signaling pathway
    • Akira S, Nishio Y, Inoue M, et al. Molecular-cloning of Aprf, a novel IFN-stimulated gene factor-3 p91-related transcription factor involved in the Gp130-mediated signaling pathway. Cell. 1994;77:63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3
  • 18
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science. 1994;264:95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 19
    • 0036256644 scopus 로고    scopus 로고
    • What does Stat3 do?
    • Levy DE, Lee CK. What does Stat3 do? J Clin Invest. 2002;109:1143-1148.
    • (2002) J Clin Invest , vol.109 , pp. 1143-1148
    • Levy, D.E.1    Lee, C.K.2
  • 20
    • 0030744123 scopus 로고    scopus 로고
    • Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
    • Wen ZL, Darnell JE. Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. Nucl Acids Res. 1997;25:2062-2067.
    • (1997) Nucl Acids Res , vol.25 , pp. 2062-2067
    • Wen, Z.L.1    Darnell, J.E.2
  • 21
    • 0032508682 scopus 로고    scopus 로고
    • Biological action of leptin as an angiogenic factor
    • Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor. Science. 1998;281:1683-1686.
    • (1998) Science , vol.281 , pp. 1683-1686
    • Sierra-Honigmann, M.R.1    Nath, A.K.2    Murakami, C.3
  • 22
    • 0035092841 scopus 로고    scopus 로고
    • Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and Akt in endothelial cells
    • Nakagami H, Morishita R, Yamamoto K, et al. Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and Akt in endothelial cells. Hypertension. 2001;37:581-586.
    • (2001) Hypertension , vol.37 , pp. 581-586
    • Nakagami, H.1    Morishita, R.2    Yamamoto, K.3
  • 23
    • 0035076453 scopus 로고    scopus 로고
    • Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway
    • Mahboubi K, Li F, Plescia J, et al. Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway. Lab Invest. 2001;81:327-334.
    • (2001) Lab Invest , vol.81 , pp. 327-334
    • Mahboubi, K.1    Li, F.2    Plescia, J.3
  • 24
    • 0141526095 scopus 로고    scopus 로고
    • IL-11 and IL-6 protect cultured human endothelial cells from H2O2-induced cell death
    • Waxman AB, Mahboubi K, Knickelbein RG, et al. IL-11 and IL-6 protect cultured human endothelial cells from H2O2-induced cell death. Am J Respir Cell Mol Biol. 2003;29:513-522.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 513-522
    • Waxman, A.B.1    Mahboubi, K.2    Knickelbein, R.G.3
  • 25
    • 18444413981 scopus 로고    scopus 로고
    • N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth
    • Hatzi E, Murphy C, Zoephel A, et al. N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth. Oncogene. 2002;21:3552-3561.
    • (2002) Oncogene , vol.21 , pp. 3552-3561
    • Hatzi, E.1    Murphy, C.2    Zoephel, A.3
  • 26
    • 85047695527 scopus 로고    scopus 로고
    • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
    • Niu GL, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene. 2002;21:2000-2008.
    • (2002) Oncogene , vol.21 , pp. 2000-2008
    • Niu, G.L.1    Wright, K.L.2    Huang, M.3
  • 27
    • 85047699589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 alpha in brain tumors: Localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
    • Schaefer LK, Ren ZY, Fuller GN, Schaefer TS. Constitutive activation of Stat3 alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2). Oncogene. 2002;21:2058-2065.
    • (2002) Oncogene , vol.21 , pp. 2058-2065
    • Schaefer, L.K.1    Ren, Z.Y.2    Fuller, G.N.3    Schaefer, T.S.4
  • 28
    • 18844444774 scopus 로고    scopus 로고
    • HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
    • Gray MJ, Zhang J, Ellis LM, et al. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene. 2005;24:3110-3120.
    • (2005) Oncogene , vol.24 , pp. 3110-3120
    • Gray, M.J.1    Zhang, J.2    Ellis, L.M.3
  • 29
    • 0037435011 scopus 로고    scopus 로고
    • Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
    • Wei LH, Kuo ML, Chen CA, et al. Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene. 2003;22:1517-1527.
    • (2003) Oncogene , vol.22 , pp. 1517-1527
    • Wei, L.H.1    Kuo, M.L.2    Chen, C.A.3
  • 30
    • 0037461934 scopus 로고    scopus 로고
    • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
    • Wei DY, Le XD, Zheng LZ, et al. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene. 2003;22:319-329.
    • (2003) Oncogene , vol.22 , pp. 319-329
    • Wei, D.Y.1    Le, X.D.2    Zheng, L.Z.3
  • 31
    • 0037375188 scopus 로고    scopus 로고
    • Expression and activation of STAT proteins during mouse retina development
    • Zhang SSM, Wei JY, Li CJ, Barnstable CJ, Fu XY. Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003;76:421-431.
    • (2003) Exp Eye Res , vol.76 , pp. 421-431
    • Ssm, Z.1    Wei, J.Y.2    Li, C.J.3    Barnstable, C.J.4    Fu, X.Y.5
  • 32
    • 3142618936 scopus 로고    scopus 로고
    • STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina
    • Zhang SS, Wei J, Qin H, et al. STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina. Invest Ophthalmol Vis Sci. 2004;45:2407-2412.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2407-2412
    • Zhang, S.S.1    Wei, J.2    Qin, H.3
  • 33
    • 0034212562 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia
    • Peterson WM, Wang Q, Tzekova R, Wiegand SJ. Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia. J Neurosci. 2000;20:4081-4090.
    • (2000) J Neurosci , vol.20 , pp. 4081-4090
    • Peterson, W.M.1    Wang, Q.2    Tzekova, R.3    Wiegand, S.J.4
  • 36
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA. 2001;98:5116-5121.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 37
    • 0017184389 scopus 로고
    • Rapid and sensitive method for quantitation of microgram quantities of protein utilizing principle of protein-dye binding
    • Bradford MM. Rapid and sensitive method for quantitation of microgram quantities of protein utilizing principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 38
    • 0026749986 scopus 로고
    • Vascular changes and their mechanisms in the feline model of retinopathy of prematurity
    • Chan-Ling T, Tout S, Hollander H, Stone J. Vascular changes and their mechanisms in the feline model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1992;33:2128-2147.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 2128-2147
    • Chan-Ling, T.1    Tout, S.2    Hollander, H.3    Stone, J.4
  • 39
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene. 2002;285:1-24.
    • (2002) Gene , vol.285 , pp. 1-24
    • Kisseleva, T.1    Bhattacharya, S.2    Braunstein, J.3    Schindler, C.W.4
  • 40
    • 0029816808 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity
    • Pierce EA, Foley ED, Smith LE. Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity. Arch Ophthalmol. 1996;114:1219-1228.
    • (1996) Arch Ophthalmol , vol.114 , pp. 1219-1228
    • Pierce, E.A.1    Foley, E.D.2    Smith, L.E.3
  • 41
    • 0030044257 scopus 로고    scopus 로고
    • Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity
    • Stone J, Chan-Ling T, Pe'er J, Itin A, Gnessin H, Keshet E. Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1996;37:290-299.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 290-299
    • Stone, J.1    Chan-Ling, T.2    Pe'Er, J.3    Itin, A.4    Gnessin, H.5    Keshet, E.6
  • 42
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci USA. 1995;92:905-909.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 905-909
    • Pierce, E.A.1    Avery, R.L.2    Foley, E.D.3    Aiello, L.P.4    Smith, L.E.5
  • 43
    • 0034013433 scopus 로고    scopus 로고
    • Activation of the JAK/STAT pathway following transient focal cerebral ischemia: Signaling through Jak1 and Stat3 in astrocytes
    • Justicia C, Gabriel C, Planas AM. Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes. Glia. 2000;30:253-270.
    • (2000) Glia , vol.30 , pp. 253-270
    • Justicia, C.1    Gabriel, C.2    Planas, A.M.3
  • 44
    • 0030466918 scopus 로고    scopus 로고
    • Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia
    • Planas AM, Soriano MA, Berruezo M, et al. Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia. Eur J Neurosci. 1996;8:2612-2618.
    • (1996) Eur J Neurosci , vol.8 , pp. 2612-2618
    • Planas, A.M.1    Soriano, M.A.2    Berruezo, M.3
  • 45
    • 0035979176 scopus 로고    scopus 로고
    • An essential role of the JAK-STAT pathway in ischemic preconditioning
    • Xuan YT, Guo YR, Han H, Zhu YQ, Bolli R. An essential role of the JAK-STAT pathway in ischemic preconditioning. Proc Natl Acad Sci USA. 2001;98:9050-9055.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9050-9055
    • Xuan, Y.T.1    Guo, Y.R.2    Han, H.3    Zhu, Y.Q.4    Bolli, R.5
  • 46
    • 0042704747 scopus 로고    scopus 로고
    • VEGF differentially activates STAT3 in microvascular endothelial cells
    • Bartoli M, Platt D, Lemtalsi T, et al. VEGF differentially activates STAT3 in microvascular endothelial cells. FASEB J. 2003;17:1562-1564.
    • (2003) FASEB J , vol.17 , pp. 1562-1564
    • Bartoli, M.1    Platt, D.2    Lemtalsi, T.3
  • 47
    • 0035733752 scopus 로고    scopus 로고
    • The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster
    • Jin W, Riley RM, Wolfinger RD, White KP, Passador-Gurgel G, Gibson G. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Nat Genet. 2001;29:389-395.
    • (2001) Nat Genet , vol.29 , pp. 389-395
    • Jin, W.1    Riley, R.M.2    Wolfinger, R.D.3    White, K.P.4    Passador-Gurgel, G.5    Gibson, G.6


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