Transforming growth factor-β-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA

Journal of Biological Chemistry

Volumn 283, Issue 20, 2008, Pages 13834-13841

  Townsend, Todd A ^a   Wrana, Jeffrey L ^b   Davis, George E ^c   Barnett, Joey V ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; CELL GROWTH; CELLS; CYTOLOGY; DIFFERENTIATION (CALCULUS); DISSOLUTION; ENZYMES; GROWTH (MATERIALS); NUCLEIC ACIDS; PATHOLOGY; PEPTIDES; PROBABILITY DENSITY FUNCTION; RNA; TISSUE CULTURE;

CELL TRANSFORMATIONS; CELLULAR PROCESSES; CONSTITUTIVELY ACTIVES; DOMINANT NEGATIVES; EFFECTIVE THERAPIES; FUNCTIONAL ROLES; HEART DISEASES; IN VITRO; IN-VIVO; MESENCHYMAL CELLS; OVEREXPRESSION; SMALL INTERFERING RNAS; TIGHT JUNCTIONS; TRANSFORMING GROWTH FACTORS; UBIQUITIN LIGASE;

ENDOTHELIAL CELLS;

PROTEIN PAR6C; PROTEIN SMURF1; REGULATOR PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; COLLAGEN; LIGAND; PROTEIN CDC42; SMALL INTERFERING RNA; SMURF1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CELL SUBPOPULATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; ENDOCARDIAL CUSHION; ENDOCARDIUM; EPITHELIAL MESENCHYMAL TRANSFORMATION; EPITHELIUM CELL; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART VALVE; MESENCHYME CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CHICK EMBRYO; CYTOLOGY; DOMINANT GENE; GENE EXPRESSION REGULATION; HEART VENTRICLE; MESODERM; METABOLISM;

ANIMALS; CDC42 GTP-BINDING PROTEIN; CHICK EMBRYO; COLLAGEN; ENDOCARDIUM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, DOMINANT; HEART VENTRICLES; LIGANDS; MESODERM; MODELS, BIOLOGICAL; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN-PROTEIN LIGASES;

EID: 46649105539     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710607200     Document Type: Article

References (62)

1. Hoffman, J. I. (1990) Pediatr. Clin. North Am. 37, 25-43
2. Hoffman, J. I., and Kaplan, S. (2002) J Am. Coll. Cardiol. 39, 1890-1900
3. Galloway, A. C., Artman, M., and Colvin, S. B. (1999) in Schwartz's Principles of Surgery, 7th Ed. (Schwartz, S. I., ed) pp. 845-908, McGraw-Hill Health Professions Division, New York
4. Mylonakis, E., and Calderwood, S. B. (2001) N. Engl. J. Med. 345, 1318-1330
5. Connolly, H. M., Crary, J. L., McGoon, M. D., Hensrud, D. D., Edwards, B. S., Edwards, W. D., and Schaff, H. V. (1997) N. Engl. J. Med. 337, 581-588
6. Robiolio, P. A., Rigolin, V. H., Wilson, J. S., Harrison, J. K., Sanders, L. L., Bashore, T. M., and Feldman, J. M. (1995) Circulation 92, 790-795
7. American Heart Association (2008) Heart and Stroke Statistical Update, Dallas, TX
8. Sadler, T. W. (1985) in Langman's Medical Embryology (Tracy, T. M., ed) pp. 168-214, Williams and Wilkins, Baltimore
9. Bernanke, D. H., and Markwald, R. R. (1982) Dev. Biol. 91, 235-245
10. Keller, B. B., and Markwald, R. R. (1998) in Hurst's the Heart, Arteries and Veins, 9th Ed. (Alexander, R. W., Schlant, R. C., and Fuster, V., eds) pp. 195-212, McGraw-Hill, Health Professions Division, New York
11. Barnett, J. V., and Desgrosellier, J. S. (2003) Birth Defects Res. Part C Embryo. Today 69, 58-72
12. Brown, C. B., Boyer, A. S., Runyan, R. B., and Barnett, J. V. (1996) Dev. Biol. 174, 248-257
13. Sugi, Y., Yamamura, H., Okagawa, H., and Markwald, R. R. (2004) Dev. Biol. 269, 505-518
14. Shi, Y., and Massague, J. (2003) Cell 113, 685-700
15. Kretzschmar, M., and Massague, J. (1998) Curr. Opin. Genet. Dev. 8, 103-111
16. Masszi, A., Di Ciano, C., Sirokmany, G., Arthur, W. T., Rotstein, O. D., Wang, J., McCulloch, C. A., Rosivall, L., Mucsi, I., and Kapus, A. (2003) Am. J. Physiol. 284, F911-F924
17. Deaton, R. A., Su, C., Valencia, T. G., and Grant, S. R. (2005) J. Biol. Chem. 280, 31172-31181
18. Bhowmick, N. A., Ghiassi, M., Aakre, M., Brown, K., Singh, V., and Moses, H. L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 15548-15553
19. Bhowmick, N. A., Ghiassi, M., Bakin, A., Aakre, M., Lundquist, C. A., Engel, M. E., Arteaga, C. L., and Moses, H. L. (2001) Mol. Biol. Cell 12, 27-36
20. Edlund, S., Landstrom, M., Heldin, C.-H., and Aspenstrom, P. (2002) Mol. Biol. Cell 13, 902-914
21. Ward, S. M., Gadbut, A. P., Tang, D., Papageorge, A. G., Wu, L., Li, G., Barnett, J. V., and Galper, J. B. (2002) J Mol. Cell Cardiol. 34, 1217-1226
22. Bakin, A. V., Rinehart, C., Tomlinson, A. K., and Arteaga, C. L. (2002) J. Cell Sci. 115, 3193-3206
23. Xie, L., Law, B. K., Chytil, A. M., Brown, K. A., Aakre, M. E., and Moses, H. L. (2004) Neoplasia 6, 603-610
24. Bakin, A. V., Tomlinson, A. K., Bhowmick, N. A., Moses, H. L., and Arteaga, C. L. (2000) J. Biol. Chem. 275, 36803-36810
25. Lopez-Casillas, F., Cheifetz, S., Doody, J., Andres, J. L., Lane, W. S., and Massague, J. (1991) Cell 67, 785-795
26. Wang, X. F., Lin, H. Y., Ng-Eaton, E., Downward, J., Lodish, H. F., and Weinberg, R. A. (1991) Cell 67, 797-805
27. Cheifetz, S., Bellon, T., Cales, C., Vera, S., Bernabeu, C., Massague, J., and Letarte, M. (1992) J. Biol. Chem. 267, 19027-19030
28. Brown, C. B., Boyer, A. S., Runyan, R. B., and Barnett, J. V. (1999) Science 283, 2080-2082
29. Compton, L. A., Potash, D. A., Brown, C. B., and Barnett, J. V. (2007) Circ. Res. 101, 784-791
30. Ozdamar, B., Bose, R., Barrios-Rodiles, M., Wang, H. R., Zhang, Y., and Wrana, J. L. (2005) Science 307, 1603-1609
31. Wang, H. R., Zhang, Y., Ozdamar, B., Ogunjimi, A. A., Alexandrova, E., Thomsen, G. H., and Wrana, J. L. (2003) Science 302, 1775-1779
32. Bose, R., and Wrana, J. L. (2006) Curr. Opin. Cell Biol. 18, 206-212
33. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W., and Vogelstein, B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2509-2514
34. Bayless, K. J., and Davis, G. E. (2002) J. Cell Sci. 115, 1123-1136
35. Desgrosellier, J. S., Mundell, N. A., McDonnell, M. A., Moses, H. L., and Barnett, J. V. (2005) Dev. Biol. 280, 201-210
36. Mercado-Pimentel, M. E., Hubbard, A. D., and Runyan, R. B. (2007) Dev. Biol. 304, 420-432
37. Tavares, A. L., Mercado-Pimentel, M. E., Runyan, R. B., and Kitten, G. T. (2006) Dev. Dyn. 235, 1589-1598
38. Goumans, M. J., Lebrin, F., and Valdimarsdottir, G. (2003) Trends Cardiovasc. Med. 13, 301-307
39. Goumans, M. J., Valdimarsdottir, G., Itoh, S., Lebrin, F., Larsson, J., Mummery, C., Karlsson, S., and ten Dijke, P. (2003) Mol. Cell 12, 817-828
40. Goumans, M. J., Valdimarsdottir, G., Itoh, S., Rosendahl, A., Sideras, P., and ten Dijke, P. (2002) EMBO J. 21, 1743-1753
41. Zhao, Z., and Rivkees, S. A. (2004) Dev. Biol. 275, 183-191
42. Sakabe, M., Ikeda, K., Nakatani, K., Kawada, N., Imanaka-Yoshida, K., Yoshida, T., Yamagishi, T., and Nakajima, Y. (2006) Dev. Dyn. 235, 94-104
43. Ishizaki, T., Uehata, M., Tamechika, I., Keel, J., Nonomura, K., Maekawa, M., and Narumiya, S. (2000) Mol. Pharmacol. 57, 976-983
44. Wang, H. R., Ogunjimi, A. A., Zhang, Y., Ozdamar, B., Bose, R., and Wrana, J. L. (2006) Methods Enzymol. 406, 437-447
45. Wang, G., and Beier, F. (2005) J. Bone Miner. Res. 20, 1022-1031
46. Wojciak-Stothard, B., Tsang, L. Y., and Haworth, S. G. (2005) Am. J. Physiol. 288, L749-L760
47. Leeuwen, F. N., Kain, H. E., Kammen, R. A., Michiels, F., Kranenburg, O. W., and Collard, J. G. (1997) J. Cell Biol. 139, 797-807
48. Storey, N. M., O'Bryan, J. P., and Armstrong, D. L. (2002) Curr. Biol. 12, 27-33
49. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massague, J. (1994) Nature 370, 341-347
50. Derynck, R., and Zhang, Y. E. (2003) Nature 425, 577-584
51. Sirard, C., Kim, S., Mirtsos, C., Tadich, P., Hoodless, P. A., Itie, A., Maxson, R., Wrana, J. L., and Mak, T. W. (2000) J. Biol. Chem. 275, 2063-2070
52. Bazzoni, G., and Dejana, E. (2004) Physiol. Rev. 84, 869-901
53. Wallez, Y., and Huber, P. (2008) Biochim. Biophys. Acta 1778, 794-809
54. Dejana, E., Spagnuolo, R., and Bazzoni, G. (2001) Thromb. Haemost. 86, 308-315
55. Bryan, B., Cai, Y., Wrighton, K., Wu, G., Feng, X. H., and Liu, M. (2005) FEBS Lett. 579, 1015-1019
56. Sahai, E., Garcia-Medina, R., Pouyssegur, J., and Vial, E. (2007) J. Cell Biol. 176, 35-42
57. Kaarbo, M., Crane, D. I., and Murrell, W. G. (2003) Dev. Dyn. 227, 35-47
58. van Nieuw Amerongen, G. P., Beckers, C. M., Achekar, I. D., Zeeman, S., Musters, R. J., and van Hinsbergh, V. W. (2007) Arterioscler. Thromb. Vasc. Biol. 27, 2332-2339
59. Wojciak-Stothard, B., and Ridley, A. J. (2002) Vascul. Pharmacol. 39, 187-199
60. Jaffe, A. B., and Hall, A. (2005) Annu. Rev. Cell Dev. Biol. 21, 247-269
61. Lin, D., Edwards, A. S., Fawcett, J. P., Mbamalu, G., Scott, J. D., and Pawson, T. (2000) Nat. Cell Biol. 2, 540-547
62. Wojciak-Stothard, B., Potempa, S., Eichholtz, T., and Ridley, A. J. (2001) J. Cell Sci. 114, 1343-1355