-
2
-
-
27744447179
-
Amyloid-beta causes apoptosis of neuronal cells via caspase cascade, which can be prevented by amyloid-beta-derived short peptides
-
Awasthi A, Matsunaga Y, Yamada T. 2005. Amyloid-beta causes apoptosis of neuronal cells via caspase cascade, which can be prevented by amyloid-beta-derived short peptides. Exp Neurol 196:282-289.
-
(2005)
Exp Neurol
, vol.196
, pp. 282-289
-
-
Awasthi, A.1
Matsunaga, Y.2
Yamada, T.3
-
3
-
-
27644493692
-
1-42 oligomer - a homogeneous and stable neuropathological protein in Alzheimer's disease
-
1-42 oligomer - a homogeneous and stable neuropathological protein in Alzheimer's disease. J Neurochem 95:834-847.
-
(2005)
J Neurochem
, vol.95
, pp. 834-847
-
-
Barghorn, S.1
Nimmrich, V.2
Striebinger, A.3
Krantz, C.4
Keller, P.5
Janson, B.6
Bahr, M.7
Schmidt, M.8
Bitner, R.S.9
Harlan, J.10
Barlow, E.11
Ebert, U.12
Hillen, H.13
-
4
-
-
5144220474
-
Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule
-
Blanchard BJ, Chen A, Rozeboom LM, Stafford KA, Weigele P, Ingram VM. 2004. Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule. Proc Natl Acad Sci U S A 101:14326-14332.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14326-14332
-
-
Blanchard, B.J.1
Chen, A.2
Rozeboom, L.M.3
Stafford, K.A.4
Weigele, P.5
Ingram, V.M.6
-
5
-
-
0026595567
-
Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs
-
Burdick D, Soreghan B, Kwon M, Kosmoski J, Knauer M, Henschen A, Yatest J, Cotman C, Glabe C. 1992. Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J Biol Chem 267:546-554.
-
(1992)
J Biol Chem
, vol.267
, pp. 546-554
-
-
Burdick, D.1
Soreghan, B.2
Kwon, M.3
Kosmoski, J.4
Knauer, M.5
Henschen, A.6
Yatest, J.7
Cotman, C.8
Glabe, C.9
-
7
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren KN, Manelli AM, Stine WB, Baker LK, Krafft GA, LaDu MJ. 2002. Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J Biol Chem 277:32046-32053.
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine, W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
8
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG. 2005. Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280:17294-17300.
-
(2005)
J Biol Chem
, vol.280
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
9
-
-
33745268224
-
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
-
Deshpende A, Mina E, Glabe C, Busciglio J. 2006. Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons. J Neurosci 26:6011-6018.
-
(2006)
J Neurosci
, vol.26
, pp. 6011-6018
-
-
Deshpende, A.1
Mina, E.2
Glabe, C.3
Busciglio, J.4
-
10
-
-
0032513029
-
Expression of ced-3 and ced-9 homologs in Alzheimer's disease cerebral cortex
-
Desjardins P, Ledoux S. 1998. Expression of ced-3 and ced-9 homologs in Alzheimer's disease cerebral cortex. Neurosci Lett 244:69-72.
-
(1998)
Neurosci Lett
, vol.244
, pp. 69-72
-
-
Desjardins, P.1
Ledoux, S.2
-
11
-
-
1342326749
-
Increased apoptotic cell death in sporadic and genetic Alzheimer's disease
-
Eckert A, Marques CA, Keil U, Schussel K, Muller WE. 2003. Increased apoptotic cell death in sporadic and genetic Alzheimer's disease. Ann N Y Acad Sci 1010:604-609.
-
(2003)
Ann N Y Acad Sci
, vol.1010
, pp. 604-609
-
-
Eckert, A.1
Marques, C.A.2
Keil, U.3
Schussel, K.4
Muller, W.E.5
-
12
-
-
0042837889
-
Caspase activation in the limbic cortex of subjects with early Alzheimer's disease
-
Gastard MC, Troncoso JC, Koliatsos VE. 2003. Caspase activation in the limbic cortex of subjects with early Alzheimer's disease. Ann Neurol 54:393-398.
-
(2003)
Ann Neurol
, vol.54
, pp. 393-398
-
-
Gastard, M.C.1
Troncoso, J.C.2
Koliatsos, V.E.3
-
13
-
-
0034697299
-
E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3
-
Giovanni A, Keramaris E, Morris EJ, Hou ST, O'Hare M, Dyson N, Robertson GS, Slack RS, Park DS. 2000. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. J Biol Chem 275:11553-11560.
-
(2000)
J Biol Chem
, vol.275
, pp. 11553-11560
-
-
Giovanni, A.1
Keramaris, E.2
Morris, E.J.3
Hou, S.T.4
O'Hare, M.5
Dyson, N.6
Robertson, G.S.7
Slack, R.S.8
Park, D.S.9
-
14
-
-
0029031348
-
1-42 peptide is cell type dependent
-
1-42 peptide is cell type dependent. J Neurochem 65:292-300.
-
(1995)
J Neurochem
, vol.65
, pp. 292-300
-
-
Gschwind, M.1
Huber, G.2
-
15
-
-
0032876784
-
Activation of caspase-3 in β-amyloid-induced apoptosis of cultured rat cortical neurons
-
Harada J, Sugimoto M. 1999. Activation of caspase-3 in β-amyloid-induced apoptosis of cultured rat cortical neurons. Brain Res 842:311-323.
-
(1999)
Brain Res
, vol.842
, pp. 311-323
-
-
Harada, J.1
Sugimoto, M.2
-
16
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297:353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
17
-
-
0030614627
-
Observation of metastable Aβ amyloid protofibrils by atomic force microscopy
-
Harper JD, Wong SS, Lieber CM, Lansbury PT. 1997. Observation of metastable Aβ amyloid protofibrils by atomic force microscopy. Chem Biol 4:119-125.
-
(1997)
Chem Biol
, vol.4
, pp. 119-125
-
-
Harper, J.D.1
Wong, S.S.2
Lieber, C.M.3
Lansbury, P.T.4
-
18
-
-
0033570337
-
Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB, Selkoe DJ. 1999. Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci 19:8876-8884.
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
Selkoe, D.J.8
-
19
-
-
0029034927
-
Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide
-
Howlett DR, Jennings KH, Lee DC, Clark MSG, Brown F, Wetzel R, Wood SJ, Camilleri P, Roberts GW. 1995. Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide. Neurodegeneration 4:23-32.
-
(1995)
Neurodegeneration
, vol.4
, pp. 23-32
-
-
Howlett, D.R.1
Jennings, K.H.2
Lee, D.C.3
Clark, M.S.G.4
Brown, F.5
Wetzel, R.6
Wood, S.J.7
Camilleri, P.8
Roberts, G.W.9
-
20
-
-
0036275638
-
Alterations in behavior, amyloid β-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease
-
Hwang DY, Chae KR, Kang TS, Hwang JH, Lim CH, Kang HK, Goo JS, Lee MR, Lim HJ, Min SH, Cho JY, Hong JT, Song CW, Paik SG, Cho JS, Kim YK. 2002. Alterations in behavior, amyloid β-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease. FASEB J 16:805-813.
-
(2002)
FASEB J
, vol.16
, pp. 805-813
-
-
Hwang, D.Y.1
Chae, K.R.2
Kang, T.S.3
Hwang, J.H.4
Lim, C.H.5
Kang, H.K.6
Goo, J.S.7
Lee, M.R.8
Lim, H.J.9
Min, S.H.10
Cho, J.Y.11
Hong, J.T.12
Song, C.W.13
Paik, S.G.14
Cho, J.S.15
Kim, Y.K.16
-
21
-
-
0027258525
-
The carboxy terminus of the amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett JT, Berger EP, Lansbury PT. 1993. The carboxy terminus of the amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury, P.T.3
-
22
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. 2003. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300:486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
23
-
-
0035993237
-
Aβ toxicity in Alzheimer's disease: Globular oligomers (ADDLs) as new vaccine and drug targets
-
Klein WL. 2002. Aβ toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets. Neurochem Int 41:345-352.
-
(2002)
Neurochem Int
, vol.41
, pp. 345-352
-
-
Klein, W.L.1
-
24
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid β oligomers
-
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. 2004. Synaptic targeting by Alzheimer's-related amyloid β oligomers. J Neurosci 24:10191-10200.
-
(2004)
J Neurosci
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
25
-
-
0028981717
-
The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LaFerla FM, Tinkle BT, Bieberich CJ, Haudenschild CC, Jay G. 1995. The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet 9:21-30.
-
(1995)
Nat Genet
, vol.9
, pp. 21-30
-
-
LaFerla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
26
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A 95:6448-6453.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
27
-
-
0034740197
-
Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies
-
Lambert MP, Viola KL, Chromy BA, Chang L, Morgan TE, Yu J, Ventou DL, Krafft GA, Finch CE, Klein WL. 2001. Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies. J Neurochem 79:595-605.
-
(2001)
J Neurochem
, vol.79
, pp. 595-605
-
-
Lambert, M.P.1
Viola, K.L.2
Chromy, B.A.3
Chang, L.4
Morgan, T.E.5
Yu, J.6
Ventou, D.L.7
Krafft, G.A.8
Finch, C.E.9
Klein, W.L.10
-
28
-
-
0030569357
-
β-Amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells
-
Li Y-P, Bushnell AF, Lee C-M, Purlmutter LS, Wong SK-F. 1996. β-Amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells. Brain Res 738:196-204.
-
(1996)
Brain Res
, vol.738
, pp. 196-204
-
-
Li, Y.-P.1
Bushnell, A.F.2
Lee, C.-M.3
Purlmutter, L.S.4
Wong, S.K.-F.5
-
29
-
-
0027257708
-
Apoptosis is induced by β-amyloid in cultured central nervous system neurons
-
Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW. 1993. Apoptosis is induced by β-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci U S A 90:7951-7955.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
-
30
-
-
0028172886
-
β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red
-
Lorenzo A, Yankner BA. 1994. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc Natl Acad Sci U S A 91:12243-12247.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
31
-
-
0034693450
-
β-Amyloid-induced activation of caspase-3 in primary cultures of rat neurons
-
Marin N, Romero B, Bosch-Morell F, Llansola M, Felipo V, Roma J. Romero FJ. 2000. β-Amyloid-induced activation of caspase-3 in primary cultures of rat neurons. Mech Ageing Dev 119:63-67.
-
(2000)
Mech Ageing Dev
, vol.119
, pp. 63-67
-
-
Marin, N.1
Romero, B.2
Bosch-Morell, F.3
Llansola, M.4
Felipo, V.5
Roma, J.6
Romero, F.J.7
-
32
-
-
0034665698
-
Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein
-
Masumura M, Hata R, Nishimura I, Uetsuki T, Sawada T, Yoshikawa K. 2000. Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein. Brain Res Mol Brain Res 80:219-227.
-
(2000)
Brain Res Mol Brain Res
, vol.80
, pp. 219-227
-
-
Masumura, M.1
Hata, R.2
Nishimura, I.3
Uetsuki, T.4
Sawada, T.5
Yoshikawa, K.6
-
33
-
-
33746269428
-
Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: Relationship to formic acid extractable Aβ42 levels
-
Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT. 2006. Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable Aβ42 levels. J Neuropathol Exp Neurol 65:508-515.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 508-515
-
-
Matsui, T.1
Ramasamy, K.2
Ingelsson, M.3
Fukumoto, H.4
Conrad, C.5
Frosch, M.P.6
Irizarry, M.C.7
Yuan, J.8
Hyman, B.T.9
-
34
-
-
0025992417
-
In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. 1991. In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res 563:311-314.
-
(1991)
Brain Res
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
35
-
-
0027447286
-
Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
-
Pike CJ, Burdick D, Walencewicz AJ, Glabe CG, Cotman CW. 1993. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci 13:1676-1687.
-
(1993)
J Neurosci
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
36
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. 2001. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol 101:305-310.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 305-310
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
Rottkamp, C.A.4
Nunomura, A.5
Siedlak, S.L.6
Boux, H.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
-
37
-
-
0037195424
-
2+ channel currents in primary cultures of rat cortical neurons by amyloid β protein (1-40) is dependent on solubility status
-
2+ channel currents in primary cultures of rat cortical neurons by amyloid β protein (1-40) is dependent on solubility status. Brain Res 956:254-261.
-
(2002)
Brain Res
, vol.956
, pp. 254-261
-
-
Ramsden, M.1
Henderson, Z.2
Pearson, H.A.3
-
38
-
-
0031170886
-
The toxicity of the Alzheimer's β-amyloid peptide correlates with a distinct fiber morphology
-
Seilheimer B, Bohrmann B, Bondolfi L, Muller F, Stuber D, Dobeli H. 1997. The toxicity of the Alzheimer's β-amyloid peptide correlates with a distinct fiber morphology. J Struct Biol 119:59-71.
-
(1997)
J Struct Biol
, vol.119
, pp. 59-71
-
-
Seilheimer, B.1
Bohrmann, B.2
Bondolfi, L.3
Muller, F.4
Stuber, D.5
Dobeli, H.6
-
39
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. 2001. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81:741-766.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
40
-
-
0032873466
-
In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease
-
Selznick LA, Holtzman DM, Han BH, Gokden M, Srinivasan AN, Johnson EM, Roth KA. 1999. In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease. J Neuropathol Exp Neurol 58:1020-1026.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1020-1026
-
-
Selznick, L.A.1
Holtzman, D.M.2
Han, B.H.3
Gokden, M.4
Srinivasan, A.N.5
Johnson, E.M.6
Roth, K.A.7
-
41
-
-
0033574268
-
Changes in caspase expression in Alzheimer's disease: Comparison with development and aging
-
Shimohama S, Tanino H, Fujimoto S. 1999. Changes in caspase expression in Alzheimer's disease: comparison with development and aging. Biochem Biophys Res Commun 256:381-384.
-
(1999)
Biochem Biophys Res Commun
, vol.256
, pp. 381-384
-
-
Shimohama, S.1
Tanino, H.2
Fujimoto, S.3
-
42
-
-
0028265912
-
Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro
-
Simmons LK, May PC, Tomaselli KJ, Rydel RE, Fuson KS, Brigham EF, Wright S, Lieberburg I, Becker GW, Brems DN. 1994. Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro. Mol Pharmacol 45:373-379.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 373-379
-
-
Simmons, L.K.1
May, P.C.2
Tomaselli, K.J.3
Rydel, R.E.4
Fuson, K.S.5
Brigham, E.F.6
Wright, S.7
Lieberburg, I.8
Becker, G.W.9
Brems, D.N.10
-
43
-
-
0029120647
-
Evidence for apoptotic cell death in Alzheimer's disease
-
Smale G, Nichols NR, Brady DR, Finch CE, Horton WE. 1995. Evidence for apoptotic cell death in Alzheimer's disease. Exp Neurol 133:225-230.
-
(1995)
Exp Neurol
, vol.133
, pp. 225-230
-
-
Smale, G.1
Nichols, N.R.2
Brady, D.R.3
Finch, C.E.4
Horton, W.E.5
-
44
-
-
0020031809
-
Nicotinic postsynaptic membranes from Torpedo: Sidedness, permeability to macromolecules, and topography of major polypeptides
-
St. John PA, Froehner SC, Goodenough DA, Cohen JB. 1982. Nicotinic postsynaptic membranes from Torpedo: sidedness, permeability to macromolecules, and topography of major polypeptides. J Cell Biol 92:333-342.
-
(1982)
J Cell Biol
, vol.92
, pp. 333-342
-
-
St. John, P.A.1
Froehner, S.C.2
Goodenough, D.A.3
Cohen, J.B.4
-
45
-
-
0038176528
-
In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis
-
Stine WB, Dahlgren KN, Krafft GA, LaDu MJ. 2003. In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis. J Biol Chem 278:11612-11622.
-
(2003)
J Biol Chem
, vol.278
, pp. 11612-11622
-
-
Stine, W.B.1
Dahlgren, K.N.2
Krafft, G.A.3
LaDu, M.J.4
-
46
-
-
0035917831
-
Activated caspase-3 expression in Alzheimer's and aged control brain: Correlation with Alzheimer pathology
-
Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW. 2001. Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Res 898:350-357.
-
(2001)
Brain Res
, vol.898
, pp. 350-357
-
-
Su, J.H.1
Zhao, M.2
Anderson, A.J.3
Srinivasan, A.4
Cotman, C.W.5
-
47
-
-
1542357632
-
Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo
-
Takuma H, Tomiyama T, Kuida K, Mori H. 2004. Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo. J Neuropathol Exp Neurol 63:255-261.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 255-261
-
-
Takuma, H.1
Tomiyama, T.2
Kuida, K.3
Mori, H.4
-
48
-
-
0034652232
-
Caspase-2 mediates neuronal cell death induced by β-amyloid
-
Troy CM, Rabacchi SA, Friedman WJ, Farppier TF, Brown K, Shelanski ML. 2000. Caspase-2 mediates neuronal cell death induced by β-amyloid. J Neurosci 20:1386-1392.
-
(2000)
J Neurosci
, vol.20
, pp. 1386-1392
-
-
Troy, C.M.1
Rabacchi, S.A.2
Friedman, W.J.3
Farppier, T.F.4
Brown, K.5
Shelanski, M.L.6
-
49
-
-
0030799122
-
Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate
-
Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB. 1997. Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate. J Biol Chem 272:22364-22372.
-
(1997)
J Biol Chem
, vol.272
, pp. 22364-22372
-
-
Walsh, D.M.1
Lomakin, A.2
Benedek, G.B.3
Condron, M.M.4
Teplow, D.B.5
-
50
-
-
0033520461
-
Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Slekoe DJ, Teplow DB. 1999. Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J Biol Chem 274:25945-25952.
-
(1999)
J Biol Chem
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
Benedek, G.B.7
Slekoe, D.J.8
Teplow, D.B.9
-
51
-
-
0028171547
-
Ultrastructural analysis of β-amyloid-induced apoptosis in cultured hippocampal neurons
-
Watt JA, Pike CJ, Walencewicz-Wasserman, Cotman CW. 1994. Ultrastructural analysis of β-amyloid-induced apoptosis in cultured hippocampal neurons. Brain Res 661:147-156.
-
(1994)
Brain Res
, vol.661
, pp. 147-156
-
-
Watt, J.A.1
Pike, C.J.2
-
52
-
-
0028122463
-
Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
-
West MJ, Coleman PD, Flood DG, Troncoso JC. 1994. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344:769-772.
-
(1994)
Lancet
, vol.344
, pp. 769-772
-
-
West, M.J.1
Coleman, P.D.2
Flood, D.G.3
Troncoso, J.C.4
-
54
-
-
18444393054
-
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
-
Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki HW, Maler M, Dyrks T, Bienert M, Beyermann M, Ruther E, Kornhuber J. 2002. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J Neurochem 81:481-496.
-
(2002)
J Neurochem
, vol.81
, pp. 481-496
-
-
Wiltfang, J.1
Esselmann, H.2
Bibl, M.3
Smirnov, A.4
Otto, M.5
Paul, S.6
Schmidt, B.7
Klafki, H.W.8
Maler, M.9
Dyrks, T.10
Bienert, M.11
Beyermann, M.12
Ruther, E.13
Kornhuber, J.14
-
55
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner BA. 1996. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 16:921-932.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
56
-
-
3543060658
-
Amyloid β-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation
-
Ye C, Walsh DM, Selkoe DJ, Hartley DM. 2004. Amyloid β-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation. Neurosci Lett 366:320-325.
-
(2004)
Neurosci Lett
, vol.366
, pp. 320-325
-
-
Ye, C.1
Walsh, D.M.2
Selkoe, D.J.3
Hartley, D.M.4
-
57
-
-
0032105394
-
The role of Aβ42 in Alzheimer's disease
-
Younkin SG. 1998. The role of Aβ42 in Alzheimer's disease. J Physiol (Paris) 92:289-292.
-
(1998)
J Physiol (Paris)
, vol.92
, pp. 289-292
-
-
Younkin, S.G.1
-
58
-
-
0034668842
-
Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8
-
Zhang Y, Goodyer C, LeBlanc A. 2000. Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8. J Neurosci 20:8384-8389.
-
(2000)
J Neurosci
, vol.20
, pp. 8384-8389
-
-
Zhang, Y.1
Goodyer, C.2
LeBlanc, A.3
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