α2β1 and αVβ1 integrin signaling pathways mediate amyloid-β-induced neurotoxicity

Neurobiology of Aging

Volumn 28, Issue 2, 2007, Pages 226-237

  Wright, Sarah ^a   Malinin, Nikolay L ^a   Powell, Kyle A ^a   Yednock, Ted ^a   Rydel, Russell E ^a   Griswold Prenner, Irene ^a  

^a ELAN PHARMACEUTICALS   (United States)

Author keywords

2 1 and V 1 integrin; Alzheimer's disease; Amyloid ; Neurodegeneration; Pyk2

Indexed keywords

ALPHAVBETA1 INTEGRIN; FOCAL ADHESION KINASE 2; INTEGRIN; VERY LATE ACTIVATION ANTIGEN 2; AMYLOID BETA PROTEIN; NEUROTOXIN;

ALZHEIMER DISEASE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; APOPTOSIS; BRAIN CORTEX; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; METABOLISM; NERVE CELL; PATHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; APOPTOSIS; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTEGRIN ALPHA2BETA1; NEURONS; NEUROTOXINS; SIGNAL TRANSDUCTION;

EID: 33845382759     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.12.002     Document Type: Article

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