-
1
-
-
0034307013
-
Molecular genetics of prostate cancer
-
Abate-Shen, C. and Shen, M.M. (2000) Molecular genetics of prostate cancer. Genes Dev 14, 2410-2434
-
(2000)
Genes Dev
, vol.14
, pp. 2410-2434
-
-
Abate-Shen, C.1
Shen, M.M.2
-
2
-
-
33846117944
-
Cystic fibrosis mouse models
-
Guilbault, C. et al. (2007) Cystic fibrosis mouse models. Am J Respir Cell Mol Biol 36, 1-7
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 1-7
-
-
Guilbault, C.1
-
3
-
-
0001256561
-
Prostate cancer in the rat
-
Dunning, WE (1963) Prostate cancer in the rat. Natl Cancer Inst Monogr 12, 351-369
-
(1963)
Natl Cancer Inst Monogr
, vol.12
, pp. 351-369
-
-
Dunning, W.E.1
-
4
-
-
0018892965
-
-
Isaacs, J.T. et al. (1980) Concepts in prostatic cancer biology: Dunning R-3327 H, HI, and AT tumors. Prog Clin Biol Res 37, 311-323
-
Isaacs, J.T. et al. (1980) Concepts in prostatic cancer biology: Dunning R-3327 H, HI, and AT tumors. Prog Clin Biol Res 37, 311-323
-
-
-
-
5
-
-
0031850354
-
High grade prostatic intraepithelial neoplasia in military working dogs with and without prostate cancer
-
Aquilina, J.W. et al. (1998) High grade prostatic intraepithelial neoplasia in military working dogs with and without prostate cancer. Prostate 36, 189-193
-
(1998)
Prostate
, vol.36
, pp. 189-193
-
-
Aquilina, J.W.1
-
6
-
-
0032811310
-
Model systems of prostate cancer: Uses and limitations
-
Navone, N.M. et al. (1998) Model systems of prostate cancer: Uses and limitations. Cancer Metastasis Rev 17, 361-371
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 361-371
-
-
Navone, N.M.1
-
7
-
-
12144290810
-
Prostate pathology of genetically engineered mice: Definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee
-
Shappell, S.B. et al. (2004) Prostate pathology of genetically engineered mice: Definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee. Cancer Res 64, 2270-2305
-
(2004)
Cancer Res
, vol.64
, pp. 2270-2305
-
-
Shappell, S.B.1
-
8
-
-
0036605972
-
Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis
-
Kim, M.J. et al. (2002) Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res 62, 2999-3004
-
(2002)
Cancer Res
, vol.62
, pp. 2999-3004
-
-
Kim, M.J.1
-
9
-
-
0032446247
-
A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells
-
Garabedian, E.M., Humphrey, P.A. and Gordon, J.I. (1998) A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells. Proc Natl Acad Sci U S A 95, 15382-15387
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15382-15387
-
-
Garabedian, E.M.1
Humphrey, P.A.2
Gordon, J.I.3
-
10
-
-
0035266381
-
A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential
-
Masumori, N. et al. (2001) A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential. Cancer Res 61, 2239-2249
-
(2001)
Cancer Res
, vol.61
, pp. 2239-2249
-
-
Masumori, N.1
-
11
-
-
0036575440
-
Mouse models of prostate carcinogenesis
-
Abate-Shen, C. and Shen, M.M. (2002) Mouse models of prostate carcinogenesis. Trends Genet 18, S1-S5
-
(2002)
Trends Genet
, vol.18
-
-
Abate-Shen, C.1
Shen, M.M.2
-
12
-
-
0345268686
-
Mouse strains for prostate tumorigenesis based on genes altered in human prostate cancer
-
Povrell, W.C. et al. (2003) Mouse strains for prostate tumorigenesis based on genes altered in human prostate cancer. Curr Drug Targets 4, 263-279
-
(2003)
Curr Drug Targets
, vol.4
, pp. 263-279
-
-
Povrell, W.C.1
-
13
-
-
0028911462
-
Prostate cancer in a transgenic mouse
-
Greenberg, N.M. et al. (1995) Prostate cancer in a transgenic mouse. Proc Natl Acad Sci U S A 92, 3431-3443
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 3431-3443
-
-
Greenberg, N.M.1
-
14
-
-
0030727885
-
Androgen-independent prostate cancer progression in the TRAMP model
-
Gingrich, J.R. et al. (1997) Androgen-independent prostate cancer progression in the TRAMP model. Cancer Res 57, 4687-4691
-
(1997)
Cancer Res
, vol.57
, pp. 4687-4691
-
-
Gingrich, J.R.1
-
15
-
-
0032087821
-
Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: A model for prostate cancer
-
Kasper, S. et al. (1998) Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: A model for prostate cancer. Lab Invest 78, i-xv
-
(1998)
Lab Invest
, vol.78
-
-
Kasper, S.1
-
16
-
-
5144225237
-
Hepsin promotes prostate cancer progression and metastasis
-
Klezovitch, O. et al. (2004) Hepsin promotes prostate cancer progression and metastasis. Cancer Cell 6, 185-195
-
(2004)
Cancer Cell
, vol.6
, pp. 185-195
-
-
Klezovitch, O.1
-
17
-
-
3042547296
-
Genetically defined mouse models that mimic natural aspects of human prostate cancer development
-
Roy-Burman, P. et al. (2004) Genetically defined mouse models that mimic natural aspects of human prostate cancer development. Endocr Relat Cancer 11, 225-254
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 225-254
-
-
Roy-Burman, P.1
-
18
-
-
0035845558
-
Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium
-
Stanbrough, M. et al. (2001) Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium. Proc Natl Acad Sci U S A 98, 10823-10828
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10823-10828
-
-
Stanbrough, M.1
-
19
-
-
2442653901
-
Prostatic intraepithelial neoplasia and intestinal metaplasia in prostates of probasin-RAS transgenic mice
-
Scherl, A. et al. (2004) Prostatic intraepithelial neoplasia and intestinal metaplasia in prostates of probasin-RAS transgenic mice. Prostate 59, 448-459
-
(2004)
Prostate
, vol.59
, pp. 448-459
-
-
Scherl, A.1
-
20
-
-
2942587152
-
Engineered FGF-2 expression induces glandular epithelial hyperplasia in the murine prostatic dorsal lobe
-
Konno-Takahashi, N. et al. (2004) Engineered FGF-2 expression induces glandular epithelial hyperplasia in the murine prostatic dorsal lobe. Eur Urol 46, 126-132
-
(2004)
Eur Urol
, vol.46
, pp. 126-132
-
-
Konno-Takahashi, N.1
-
21
-
-
0141731322
-
Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer
-
Polnaszek, N. et al. (2003) Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Res 63, 5754-5760
-
(2003)
Cancer Res
, vol.63
, pp. 5754-5760
-
-
Polnaszek, N.1
-
22
-
-
0036993587
-
Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice
-
Foster, B.A. et al. (2002) Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice. Differentiation 70, 624-632
-
(2002)
Differentiation
, vol.70
, pp. 624-632
-
-
Foster, B.A.1
-
23
-
-
0034547972
-
The effect of fibroblast growth factor 8, isoform b, on the biology of prostate carcinoma cells and their interaction with stromal cells
-
Song, Z. et al. (2000) The effect of fibroblast growth factor 8, isoform b, on the biology of prostate carcinoma cells and their interaction with stromal cells. Cancer Res 60, 6730-6736
-
(2000)
Cancer Res
, vol.60
, pp. 6730-6736
-
-
Song, Z.1
-
24
-
-
0036733760
-
Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: A new mouse model for prostatic intraepithelial neoplasia
-
Song, Z. et al. (2002) Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: A new mouse model for prostatic intraepithelial neoplasia. Cancer Res 62, 5096-5105
-
(2002)
Cancer Res
, vol.62
, pp. 5096-5105
-
-
Song, Z.1
-
25
-
-
0345734275
-
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice
-
Freeman, K.W. et al. (2003) Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res 63, 8256-8263
-
(2003)
Cancer Res
, vol.63
, pp. 8256-8263
-
-
Freeman, K.W.1
-
26
-
-
0347320788
-
Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate
-
Jin, C. et al. (2003) Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Res 63, 8784-8790
-
(2003)
Cancer Res
, vol.63
, pp. 8784-8790
-
-
Jin, C.1
-
27
-
-
0038662735
-
Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin
-
Kindblom, J. et al. (2003) Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin. Endocrinology 144, 2269-2278
-
(2003)
Endocrinology
, vol.144
, pp. 2269-2278
-
-
Kindblom, J.1
-
28
-
-
0037379776
-
Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate
-
Shim, E.H. et al. (2003) Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate. Cancer Res 63, 1583-1588
-
(2003)
Cancer Res
, vol.63
, pp. 1583-1588
-
-
Shim, E.H.1
-
29
-
-
0038271762
-
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT model
-
Majumder, P. K. et al. (2003) Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT model. Proc Natl Acad Sci U S A 100, 7841-7846
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7841-7846
-
-
Majumder, P.K.1
-
30
-
-
0141569009
-
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
-
Ellwood-Yen, K. et al. (2003) Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4, 223-238
-
(2003)
Cancer Cell
, vol.4
, pp. 223-238
-
-
Ellwood-Yen, K.1
-
31
-
-
14944360231
-
Knockin of SV40 Tag oncogene in a mouse adenocarcinoma of the prostate model demonstrates advantageous features over the transgenic model
-
Duan, W et al. (2005) Knockin of SV40 Tag oncogene in a mouse adenocarcinoma of the prostate model demonstrates advantageous features over the transgenic model. Oncogene 24, 1510-1524
-
(2005)
Oncogene
, vol.24
, pp. 1510-1524
-
-
Duan, W.1
-
32
-
-
0036892926
-
Prostate targeting: PSP94 gene promoter/ enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model
-
Gabril, M.Y. et al. (2002) Prostate targeting: PSP94 gene promoter/ enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model. Gene Ther 9, 1589-1599
-
(2002)
Gene Ther
, vol.9
, pp. 1589-1599
-
-
Gabril, M.Y.1
-
33
-
-
11144350221
-
Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice
-
Kelavkar, U.P. et al. (2004) Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice. Neoplasia 6, 821-830
-
(2004)
Neoplasia
, vol.6
, pp. 821-830
-
-
Kelavkar, U.P.1
-
34
-
-
33745839267
-
Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: The FLiMP mouse model
-
Kelavkar, U.P. et al. (2006) Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: The FLiMP mouse model. Neoplasia 8, 510-522
-
(2006)
Neoplasia
, vol.8
, pp. 510-522
-
-
Kelavkar, U.P.1
-
35
-
-
0037699032
-
Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma
-
Shappell, S.B. et al. (2003) Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma. Cancer Res 63, 2256-2267
-
(2003)
Cancer Res
, vol.63
, pp. 2256-2267
-
-
Shappell, S.B.1
-
36
-
-
0036174513
-
Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia
-
Abdulkadir, S.A. et al. (2002) Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol 22, 1493-1503
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1493-1503
-
-
Abdulkadir, S.A.1
-
37
-
-
0033561173
-
Roles for Nkx3.1 in prostate development and cancer
-
Bhatia-Gaur, R. et al. (1999) Roles for Nkx3.1 in prostate development and cancer. Genes Dev 13, 966-977
-
(1999)
Genes Dev
, vol.13
, pp. 966-977
-
-
Bhatia-Gaur, R.1
-
38
-
-
4344577121
-
Conditional deletion of Rb causes early stage prostate cancer
-
Maddison, L.A. et al. (2004) Conditional deletion of Rb causes early stage prostate cancer. Cancer Res 64, 6018-6025
-
(2004)
Cancer Res
, vol.64
, pp. 6018-6025
-
-
Maddison, L.A.1
-
39
-
-
13044292640
-
Generation and reproductive phenotypes of mice lacking estrogen receptor beta
-
Krege, J.H. et al. (1998) Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc Natl Acad Sci U S A 95, 15677-15682
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15677-15682
-
-
Krege, J.H.1
-
40
-
-
0035881269
-
Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: Studies with alphaERKO and betaERKO mice
-
Prins, G.S. et al. (2001) Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: Studies with alphaERKO and betaERKO mice. Cancer Res 61, 6089-6097
-
(2001)
Cancer Res
, vol.61
, pp. 6089-6097
-
-
Prins, G.S.1
-
41
-
-
14344284951
-
A role for estrogen receptor beta in the regulation of growth of the ventral prostate
-
Weihua, Z. et al. (2001) A role for estrogen receptor beta in the regulation of growth of the ventral prostate. Proc Natl Acad Sci U S A 98, 6330-6335
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6330-6335
-
-
Weihua, Z.1
-
42
-
-
4243110417
-
Pten dose dictates cancer progression in the prostate
-
Trotman, L.C. et al. (2003) Pten dose dictates cancer progression in the prostate. PLoS Biol 1, e59.
-
(2003)
PLoS Biol
, vol.1
-
-
Trotman, L.C.1
-
43
-
-
10744222860
-
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
-
Wang, S. et al. (2003) Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell 4, 209-221
-
(2003)
Cancer Cell
, vol.4
, pp. 209-221
-
-
Wang, S.1
-
44
-
-
34047265189
-
Inactivation of Apc in the mouse prostate causes prostate carcinoma
-
Bruxvoort, K.J. et al. (2007) Inactivation of Apc in the mouse prostate causes prostate carcinoma. Cancer Res 67, 2490-2496
-
(2007)
Cancer Res
, vol.67
, pp. 2490-2496
-
-
Bruxvoort, K.J.1
-
45
-
-
32244441735
-
Mechanisms of prostate tumorigenesis: Roles for transcription factors Nkx.1 and Egr1
-
Abdulkadir, S.A. (2005) Mechanisms of prostate tumorigenesis: Roles for transcription factors Nkx.1 and Egr1. Ann N Y Acad Sci 1059, 33-40
-
(2005)
Ann N Y Acad Sci
, vol.1059
, pp. 33-40
-
-
Abdulkadir, S.A.1
-
46
-
-
0034746302
-
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
-
Di Cristofano, A. et al. (2001) Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse. Nat Genet 27, 222-224
-
(2001)
Nat Genet
, vol.27
, pp. 222-224
-
-
Di Cristofano, A.1
-
47
-
-
0037022364
-
Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice
-
You, M.J. et al. (2002) Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proc Natl Acad Sci U S A 99, 1455-1460
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 1455-1460
-
-
You, M.J.1
-
48
-
-
0035949707
-
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
-
Kwabi-Addo, B. et al. (2001) Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proc Natl Acad Sci U S A 98, 11563-11568
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11563-11568
-
-
Kwabi-Addo, B.1
-
49
-
-
0037022663
-
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
-
Kim, M.J. et al. (2002) Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proc Natl Acad Sci U S A 99, 2884-2889
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2884-2889
-
-
Kim, M.J.1
-
50
-
-
33745172528
-
The deficiency of Akt1 is sufficient to suppress tumor development in Pten +/- mice
-
Chen, M.L. et al. (2006) The deficiency of Akt1 is sufficient to suppress tumor development in Pten +/- mice. Genes Dev 20, 1569-1574
-
(2006)
Genes Dev
, vol.20
, pp. 1569-1574
-
-
Chen, M.L.1
-
51
-
-
33644513051
-
Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis
-
Zhong, C. et al. (2006) Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis. Cancer Res 66, 2188-2194
-
(2006)
Cancer Res
, vol.66
, pp. 2188-2194
-
-
Zhong, C.1
-
52
-
-
33748078111
-
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer
-
Zhou, Z. et al. (2006) Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res 66 7889-7898
-
(2006)
Cancer Res
, vol.66
, pp. 7889-7898
-
-
Zhou, Z.1
-
53
-
-
0027479319
-
Characterization of two cis- acting DNA elements involved in the androgen regulation of the probasin gene
-
Rennie, P.S. et al. (1993) Characterization of two cis- acting DNA elements involved in the androgen regulation of the probasin gene. Mol Endocrinol 7, 23-36
-
(1993)
Mol Endocrinol
, vol.7
, pp. 23-36
-
-
Rennie, P.S.1
-
54
-
-
0027960980
-
Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene
-
Kasper, S. et al. (1994) Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene. J Biol Chem 269, 31763-31769
-
(1994)
J Biol Chem
, vol.269
, pp. 31763-31769
-
-
Kasper, S.1
-
55
-
-
0031920589
-
Relative activity and specificity of promoters from prostate-expressed genes
-
Brookes, D.E. et al. (1998) Relative activity and specificity of promoters from prostate-expressed genes. Prostate 35, 18-26
-
(1998)
Prostate
, vol.35
, pp. 18-26
-
-
Brookes, D.E.1
-
56
-
-
0030927430
-
Large fragment of the probasin promoter targets high levels of transgene expression to the prostate of transgenic mice
-
Yan, Y. et al. (1997) Large fragment of the probasin promoter targets high levels of transgene expression to the prostate of transgenic mice. Prostate 32, 129-139
-
(1997)
Prostate
, vol.32
, pp. 129-139
-
-
Yan, Y.1
-
57
-
-
0034520311
-
A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
-
Zhang, J. et al. (2000) A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology 141, 4698-4710
-
(2000)
Endocrinology
, vol.141
, pp. 4698-4710
-
-
Zhang, J.1
-
58
-
-
0035113825
-
Generation of a prostate epithehal cell-specific Cre transgenic mouse model for tissue-specific gene ablation
-
Wu, X. et al. (2001) Generation of a prostate epithehal cell-specific Cre transgenic mouse model for tissue-specific gene ablation. Mech Dev 101, 61-69
-
(2001)
Mech Dev
, vol.101
, pp. 61-69
-
-
Wu, X.1
-
59
-
-
0029903593
-
Progression of prostatic intraepithelial neoplasia to invasive carcinoma in C3(1)/SV40 large T antigen transgenic mice: Histopathological and molecular biological alterations
-
Shibata, M.A. et al. (1996) Progression of prostatic intraepithelial neoplasia to invasive carcinoma in C3(1)/SV40 large T antigen transgenic mice: Histopathological and molecular biological alterations. Cancer Res 56, 4894-4903
-
(1996)
Cancer Res
, vol.56
, pp. 4894-4903
-
-
Shibata, M.A.1
-
60
-
-
0025776414
-
Restriction of neuroblastoma to the prostate gland in transgenic mice
-
Skalnik, D.G. et al. (1991) Restriction of neuroblastoma to the prostate gland in transgenic mice. Mol Cell Biol 11, 4518-4527
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4518-4527
-
-
Skalnik, D.G.1
-
61
-
-
0027963412
-
Immunocytochemical comparison of cultured normal epithelial prostatic cells with prostatic tissue sections
-
Cussenot, O. et al. (1994) Immunocytochemical comparison of cultured normal epithelial prostatic cells with prostatic tissue sections. Exp Cell Res 214, 83-92
-
(1994)
Exp Cell Res
, vol.214
, pp. 83-92
-
-
Cussenot, O.1
-
62
-
-
0029825212
-
Androgen receptor expression in prostatic dysplasia (prostatic intraepithelial neoplasia) in the human prostate: An immunohistochemical and in situ hybridization study
-
Leav, I. et al. (1996) Androgen receptor expression in prostatic dysplasia (prostatic intraepithelial neoplasia) in the human prostate: an immunohistochemical and in situ hybridization study. Prostate 29, 137-145
-
(1996)
Prostate
, vol.29
, pp. 137-145
-
-
Leav, I.1
-
63
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman, B.J. and Feldman, D. (2001) The development of androgen-independent prostate cancer. Nat Rev Cancer 1, 34-45
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
64
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen, C.D. et al. (2004) Molecular determinants of resistance to antiandrogen therapy. Nat Med 10, 33-39
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
-
65
-
-
0031600117
-
The heparan sulfate-fibroblast growth factor family: Diversity of structure and function
-
McKeehan, W.L., Wang, F. and Kan, M. (1998) The heparan sulfate-fibroblast growth factor family: Diversity of structure and function. Prog Nucleic Acid Res Mol Biol 59, 135-176
-
(1998)
Prog Nucleic Acid Res Mol Biol
, vol.59
, pp. 135-176
-
-
McKeehan, W.L.1
Wang, F.2
Kan, M.3
-
66
-
-
0026736833
-
The FGF family of growth factors and oncogenes
-
Basilico, C. and Moscatelli, D. (1992) The FGF family of growth factors and oncogenes. Adv Cancer Res 59, 115-165
-
(1992)
Adv Cancer Res
, vol.59
, pp. 115-165
-
-
Basilico, C.1
Moscatelli, D.2
-
67
-
-
0026443794
-
Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors
-
Cunha, G.R. et al. (1992) Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors. J Androl 13, 465-475
-
(1992)
J Androl
, vol.13
, pp. 465-475
-
-
Cunha, G.R.1
-
68
-
-
9744241715
-
Fibroblast growth factor 17 is over-expressed in human prostate cancer
-
Heer, R. et al. (2004) Fibroblast growth factor 17 is over-expressed in human prostate cancer. J Pathol 204, 578-586
-
(2004)
J Pathol
, vol.204
, pp. 578-586
-
-
Heer, R.1
-
69
-
-
0035814437
-
Role of fibroblast growth factor receptor signaling in prostate cancer cell survival
-
Ozen, M. et al. (2001) Role of fibroblast growth factor receptor signaling in prostate cancer cell survival. J Natl Cancer Inst 93, 1783-1790
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1783-1790
-
-
Ozen, M.1
-
70
-
-
0033899969
-
Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer
-
Ropiquet, F. et al. (2000) Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res 60, 4245-4250
-
(2000)
Cancer Res
, vol.60
, pp. 4245-4250
-
-
Ropiquet, F.1
-
71
-
-
0033010983
-
Characterization of the FGF axis and identification of a novel FGFR1iiic isoform during prostate cancer progression in the TRAMP model
-
Foster, B.A., Kaplan, P.J. and Greenberg, N.M. (1999) Characterization of the FGF axis and identification of a novel FGFR1iiic isoform during prostate cancer progression in the TRAMP model. Prostate Cancer Prostatic Dis 2, 76-82
-
(1999)
Prostate Cancer Prostatic Dis
, vol.2
, pp. 76-82
-
-
Foster, B.A.1
Kaplan, P.J.2
Greenberg, N.M.3
-
72
-
-
0029102885
-
Keratinocyte growth factor
-
Rubin, J.S. et al. (1995) Keratinocyte growth factor. Cell Biol Int 19, 399-411
-
(1995)
Cell Biol Int
, vol.19
, pp. 399-411
-
-
Rubin, J.S.1
-
73
-
-
0005307025
-
Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate
-
Sugimura, Y. et al. (1996) Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate. Int J Dev Biol 40, 941-951
-
(1996)
Int J Dev Biol
, vol.40
, pp. 941-951
-
-
Sugimura, Y.1
-
74
-
-
0029493392
-
Keratinocyte growth factor and receptor mRNA expression in benign and malignant human prostate
-
McGarvey, T.W. and Stearns, M.E. (1995) Keratinocyte growth factor and receptor mRNA expression in benign and malignant human prostate. Exp Mol Pathol 63, 52-62
-
(1995)
Exp Mol Pathol
, vol.63
, pp. 52-62
-
-
McGarvey, T.W.1
Stearns, M.E.2
-
75
-
-
0030860498
-
Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model
-
Foster, B.A. et al. (1997) Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model. Cancer Res 57, 3325-3330
-
(1997)
Cancer Res
, vol.57
, pp. 3325-3330
-
-
Foster, B.A.1
-
76
-
-
0037220643
-
Differential expression of specific FGF ligand and receptor isoforms during angiogenesis associated with prostate cancer progression
-
Huss, W.J. et al. (2003) Differential expression of specific FGF ligand and receptor isoforms during angiogenesis associated with prostate cancer progression. Prostate 54, 8-16
-
(2003)
Prostate
, vol.54
, pp. 8-16
-
-
Huss, W.J.1
-
77
-
-
0033614366
-
FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease
-
Dorkin, T.J. et al. (1999) FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease. Oncogene 18, 2755-2761
-
(1999)
Oncogene
, vol.18
, pp. 2755-2761
-
-
Dorkin, T.J.1
-
78
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke, T.F. et al. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275, 665-668
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
-
79
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu, X. et al. (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 95, 15587-15591
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
-
80
-
-
0033551374
-
MYC oncogenes and human neoplastic disease
-
Nesbit, C.E., Tersak, J.M. and Prochownik, E.V. (1999) MYC oncogenes and human neoplastic disease. Oncogene 18, 3004-3016
-
(1999)
Oncogene
, vol.18
, pp. 3004-3016
-
-
Nesbit, C.E.1
Tersak, J.M.2
Prochownik, E.V.3
-
81
-
-
10644292399
-
Characterization of initiation of angiogenesis in early stages of prostate adenocarcinoma development and progression in a transgenic murine model
-
Gabril, M. et al. (2004) Characterization of initiation of angiogenesis in early stages of prostate adenocarcinoma development and progression in a transgenic murine model. Urology 64, 1233-1237
-
(2004)
Urology
, vol.64
, pp. 1233-1237
-
-
Gabril, M.1
-
82
-
-
27744579600
-
Establishment of a serum tumor marker for preclinical trials of mouse prostate cancer models
-
Huizen, I.V. et al. (2005) Establishment of a serum tumor marker for preclinical trials of mouse prostate cancer models. Clin Cancer Res 11, 7911-7919
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7911-7919
-
-
Huizen, I.V.1
-
83
-
-
0028395411
-
Targeted gene replacement
-
Capecchi, M.R. (1994) Targeted gene replacement. Sci Am 270, 52-59
-
(1994)
Sci Am
, vol.270
, pp. 52-59
-
-
Capecchi, M.R.1
-
84
-
-
0028916152
-
Death before birth: Clues from gene knockouts and mutations
-
Copp, A.J. (1995) Death before birth: Clues from gene knockouts and mutations. Trends Genet 11, 87-93
-
(1995)
Trends Genet
, vol.11
, pp. 87-93
-
-
Copp, A.J.1
-
85
-
-
0034059140
-
Cre recombinase: The universal reagent for genome tailoring
-
Nagy, A. (2000) Cre recombinase: The universal reagent for genome tailoring. Genesis 26, 99-109
-
(2000)
Genesis
, vol.26
, pp. 99-109
-
-
Nagy, A.1
-
86
-
-
0024041732
-
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
-
Sauer, B. and Henderson, N. (1988) Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc Natl Acad Sci U S A 85, 5166-5170
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 5166-5170
-
-
Sauer, B.1
Henderson, N.2
-
87
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano, P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21, 70-71
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
88
-
-
0034326839
-
Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression
-
Bowen, C. et al. (2000) Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression. Cancer Res 60, 6111-6115
-
(2000)
Cancer Res
, vol.60
, pp. 6111-6115
-
-
Bowen, C.1
-
89
-
-
0035740250
-
Chromosomal deletions and tumor suppressor genes in prostate cancer
-
Dong, J.T. (2001) Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Metastasis Rev 20, 173-193
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 173-193
-
-
Dong, J.T.1
-
90
-
-
0029768633
-
Prostate-specific and androgen-dependent expression of a novel homeobox gene
-
Bieberich, C.J. et al. (1996) Prostate-specific and androgen-dependent expression of a novel homeobox gene. J Biol Chem 271, 31779-31782
-
(1996)
J Biol Chem
, vol.271
, pp. 31779-31782
-
-
Bieberich, C.J.1
-
91
-
-
36849085489
-
Loss of Nkx3.1 expression in the transgenic adenocarcinoma of mouse prostate model
-
Bethel, C.R. and Bieberich, C.J. (2007) Loss of Nkx3.1 expression in the transgenic adenocarcinoma of mouse prostate model. Prostate 67, 1740-1750
-
(2007)
Prostate
, vol.67
, pp. 1740-1750
-
-
Bethel, C.R.1
Bieberich, C.J.2
-
92
-
-
0033770625
-
Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands
-
Tanaka, M. et al. (2000) Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn 219, 248-260
-
(2000)
Dev Dyn
, vol.219
, pp. 248-260
-
-
Tanaka, M.1
-
93
-
-
0033856110
-
PTEN, a unique tumor suppressor gene
-
Dahia, P.L. (2000) PTEN, a unique tumor suppressor gene. Endocr. Relat Cancer 7, 115-129
-
(2000)
Endocr. Relat Cancer
, vol.7
, pp. 115-129
-
-
Dahia, P.L.1
-
94
-
-
0031964511
-
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues
-
Suzuki, H. et al. (1998) Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res 58, 204-209
-
(1998)
Cancer Res
, vol.58
, pp. 204-209
-
-
Suzuki, H.1
-
95
-
-
0031870959
-
Pten is essential for embryonic development and tumour suppression
-
Di Cristofano, A. et al. (1998) Pten is essential for embryonic development and tumour suppression. Nat Genet 19, 348-355
-
(1998)
Nat Genet
, vol.19
, pp. 348-355
-
-
Di Cristofano, A.1
-
96
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
Podsypanina, K. et al. (1999) Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci U S A 96, 1563-1568
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
-
97
-
-
0034234268
-
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten +/- mice
-
Stambolic, V. et al. (2000) High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten +/- mice. Cancer Res 60, 3605-3611
-
(2000)
Cancer Res
, vol.60
, pp. 3605-3611
-
-
Stambolic, V.1
-
98
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy, G.R. (2002) Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2, 584-593
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
99
-
-
0028345201
-
Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma
-
Brewster, S.F., Browne, S. and Brown, K.W. (1994) Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma. J Urol 151, 1073-1077
-
(1994)
J Urol
, vol.151
, pp. 1073-1077
-
-
Brewster, S.F.1
Browne, S.2
Brown, K.W.3
-
100
-
-
0028295587
-
Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer
-
Phillips, S.M. et al. (1994) Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer. Br J Urol 73, 390-395
-
(1994)
Br J Urol
, vol.73
, pp. 390-395
-
-
Phillips, S.M.1
-
101
-
-
19944429845
-
A quantitative promoter methylation profile of prostate cancer
-
Jeronimo, C. et al. (2004) A quantitative promoter methylation profile of prostate cancer. Clin. Cancer Res 10, 8472-8478
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 8472-8478
-
-
Jeronimo, C.1
-
102
-
-
12144289173
-
Hypermethylation of CpG islands in primary and metastatic human prostate cancer
-
Yegnasubramanian, S. et al. (2004) Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Res 64, 1975-1986
-
(2004)
Cancer Res
, vol.64
, pp. 1975-1986
-
-
Yegnasubramanian, S.1
-
103
-
-
0033037541
-
The INK4A/ARF locus and its two gene products
-
Sharpless, N.E. and DePinho, R.A. (1999) The INK4A/ARF locus and its two gene products. Curr Opin Genet Dev 9, 22-30
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 22-30
-
-
Sharpless, N.E.1
DePinho, R.A.2
-
104
-
-
0034745679
-
Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer
-
Burri, N. et al. (2001) Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer. Lab Invest 81, 217-229
-
(2001)
Lab Invest
, vol.81
, pp. 217-229
-
-
Burri, N.1
-
105
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen, Z. et al. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436, 725-730
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
-
106
-
-
0043244937
-
Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases
-
Abate-Shen, C. et al. (2003) Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Res 63, 3886-3890
-
(2003)
Cancer Res
, vol.63
, pp. 3886-3890
-
-
Abate-Shen, C.1
-
107
-
-
33749254070
-
Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer
-
Gao, H. et al. (2006) Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proc Natl Acad Sci U S A 103, 14477-14482
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14477-14482
-
-
Gao, H.1
-
108
-
-
33748038440
-
Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice
-
Gao, H. et al. (2006) Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Res 66, 7929-7933
-
(2006)
Cancer Res
, vol.66
, pp. 7929-7933
-
-
Gao, H.1
-
109
-
-
2942724235
-
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
-
Majumder, P.K. et al. (2004) mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nat Med 10, 594-601
-
(2004)
Nat Med
, vol.10
, pp. 594-601
-
-
Majumder, P.K.1
-
110
-
-
0034655083
-
E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse
-
Wechter, W.J. et al. (2000) E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse. Cancer Res 60, 2203-2208
-
(2000)
Cancer Res
, vol.60
, pp. 2203-2208
-
-
Wechter, W.J.1
-
111
-
-
2342625403
-
Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model
-
Gupta, S. et al. (2004) Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Res 64, 3334-3343
-
(2004)
Cancer Res
, vol.64
, pp. 3334-3343
-
-
Gupta, S.1
-
112
-
-
9344225155
-
Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model
-
Narayanan, B.A. et al. (2004) Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Clin Cancer Res 10, 7727-7737
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7727-7737
-
-
Narayanan, B.A.1
-
113
-
-
33646438584
-
Genetically engineered murine models of prostate cancer: Insights into mechanisms of tumorigenesis and potential utility
-
Abdulkadir, S.A. and Kim, J. (2005) Genetically engineered murine models of prostate cancer: Insights into mechanisms of tumorigenesis and potential utility. Future Oncol 1, 351-360
-
(2005)
Future Oncol
, vol.1
, pp. 351-360
-
-
Abdulkadir, S.A.1
Kim, J.2
-
114
-
-
34250355904
-
Chemopreventive and bioenergetic signaling effects of PDK1/Akt pathway inhibition in a transgenic mouse model of prostate cancer
-
Sargeant, A.M. et al. (2007) Chemopreventive and bioenergetic signaling effects of PDK1/Akt pathway inhibition in a transgenic mouse model of prostate cancer. Toxicol Pathol 35, 549-561
-
(2007)
Toxicol Pathol
, vol.35
, pp. 549-561
-
-
Sargeant, A.M.1
-
115
-
-
33947626040
-
Genistein chemoprevention of prostate cancer in TRAMP mice
-
Wang, J., Eltoum, I.E. and Lamartiniere, C.A. (2007) Genistein chemoprevention of prostate cancer in TRAMP mice. J Carcinog 6, 3
-
(2007)
J Carcinog
, vol.6
, pp. 3
-
-
Wang, J.1
Eltoum, I.E.2
Lamartiniere, C.A.3
-
116
-
-
0030917448
-
Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells
-
Chanvitayapongs, S., Draczynska-Lusiak, B. and Sun, A.Y. (1997) Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells. Neuroreport 8, 1499-1502
-
(1997)
Neuroreport
, vol.8
, pp. 1499-1502
-
-
Chanvitayapongs, S.1
Draczynska-Lusiak, B.2
Sun, A.Y.3
-
117
-
-
34848893955
-
Resveratrol suppresses prostate cancer progression in transgenic mice
-
Harper, C.E. et al. (2007) Resveratrol suppresses prostate cancer progression in transgenic mice. Carcinogenesis 28, 1946-1953
-
(2007)
Carcinogenesis
, vol.28
, pp. 1946-1953
-
-
Harper, C.E.1
-
118
-
-
0035964175
-
Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
-
Gupta, S. et al. (2001) Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci USA 98, 10350-10355
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10350-10355
-
-
Gupta, S.1
-
119
-
-
0034665334
-
Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice
-
Gupta, S. et al. (2000) Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice. Cancer Res 60, 5125-5133
-
(2000)
Cancer Res
, vol.60
, pp. 5125-5133
-
-
Gupta, S.1
-
120
-
-
4544361438
-
Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer
-
Huss, W.J. et al. (2004) Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer. Prostate 61, 142-152
-
(2004)
Prostate
, vol.61
, pp. 142-152
-
-
Huss, W.J.1
-
121
-
-
34250827944
-
Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice
-
Raina, K. et al. (2007) Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice. Cancer Res 67, 5976-5982
-
(2007)
Cancer Res
, vol.67
, pp. 5976-5982
-
-
Raina, K.1
-
122
-
-
4143058248
-
Antioxidants block prostate cancer in lady transgenic mice
-
Venkateswaran, V. et al. (2004) Antioxidants block prostate cancer in lady transgenic mice. Cancer Res 64, 5891-5896
-
(2004)
Cancer Res
, vol.64
, pp. 5891-5896
-
-
Venkateswaran, V.1
-
123
-
-
0033869485
-
Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model
-
Raghow, S. et al. (2000) Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model. Cancer Res 60, 4093-4097.
-
(2000)
Cancer Res
, vol.60
, pp. 4093-4097
-
-
Raghow, S.1
-
124
-
-
0036494569
-
Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model
-
Raghow, S. et al. (2002) Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model. Cancer Res 62, 1370-1376
-
(2002)
Cancer Res
, vol.62
, pp. 1370-1376
-
-
Raghow, S.1
-
125
-
-
0028798184
-
Principle of the bark of Phellodendron amurense to suppress the cellular immune response: Effect of phellodendrine on cellular and humoral immune responses
-
Mori, H. et al. (1995) Principle of the bark of Phellodendron amurense to suppress the cellular immune response: Effect of phellodendrine on cellular and humoral immune responses. Planta Med 61, 45-49
-
(1995)
Planta Med
, vol.61
, pp. 45-49
-
-
Mori, H.1
-
126
-
-
34249089950
-
Akt/cAMP-responsive element binding protein/ cyclin D1 network: A novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract
-
Kumar, A.P. et al. (2007) Akt/cAMP-responsive element binding protein/ cyclin D1 network: A novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract. Clin Cancer Res 13, 2784-2794
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2784-2794
-
-
Kumar, A.P.1
-
127
-
-
0034194329
-
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade
-
Hurwitz, A.A. et al. (2000) Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade. Cancer Res 60, 2444-2448
-
(2000)
Cancer Res
, vol.60
, pp. 2444-2448
-
-
Hurwitz, A.A.1
-
128
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
Linsley, P.S. et al. (1991) CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 174, 561-569
-
(1991)
J Exp Med
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
-
129
-
-
0042807497
-
Application of the transgenic adenocarcinoma mouse prostate (TRAMP) model for pre-clinical therapeutic studies
-
Martiniello-Wilks, R. et al. (2003) Application of the transgenic adenocarcinoma mouse prostate (TRAMP) model for pre-clinical therapeutic studies. Anticancer Res 23, 2633-2642
-
(2003)
Anticancer Res
, vol.23
, pp. 2633-2642
-
-
Martiniello-Wilks, R.1
-
130
-
-
34250843284
-
Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model
-
Isayeva, T. et al. (2007) Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model. Cancer Res 67, 5789-5797
-
(2007)
Cancer Res
, vol.67
, pp. 5789-5797
-
-
Isayeva, T.1
-
131
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein, M., McVey, M. and Guarente, L. (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13, 2570-2580
-
(1999)
Genes Dev
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
132
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A. et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
-
133
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen, H.Y. et al. (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305, 390-392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
-
134
-
-
34547100073
-
SIRT1 is significantly elevated in mouse and human prostate cancer
-
Huffman, D.M. et al. (2007) SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res 67, 6612-6618
-
(2007)
Cancer Res
, vol.67
, pp. 6612-6618
-
-
Huffman, D.M.1
-
135
-
-
8444220925
-
Molecular biomarker in prostate cancer: The role of CpG island hypermethylation
-
Bastian, P.J. et al. (2004) Molecular biomarker in prostate cancer: The role of CpG island hypermethylation. Eur Urol 46, 698-708
-
(2004)
Eur Urol
, vol.46
, pp. 698-708
-
-
Bastian, P.J.1
-
136
-
-
0036186811
-
DNA methyltransferase and demethylase in human prostate cancer
-
Patra, S.K. et al. (2002) DNA methyltransferase and demethylase in human prostate cancer. Mol. Carcinog. 33, 163-171
-
(2002)
Mol. Carcinog
, vol.33
, pp. 163-171
-
-
Patra, S.K.1
-
137
-
-
31544458225
-
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer
-
McCabe, M.T. et al. (2006) Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. Cancer Res 66, 385-392
-
(2006)
Cancer Res
, vol.66
, pp. 385-392
-
-
McCabe, M.T.1
-
138
-
-
0036359767
-
Scaling down imaging: Molecular mapping of cancer in mice
-
Weissleder, R. (2002) Scaling down imaging: Molecular mapping of cancer in mice. Nat Rev Cancer 2, 11-18
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 11-18
-
-
Weissleder, R.1
-
139
-
-
0037338436
-
Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
-
Massoud, T.F. and Gambhir, S.S. (2003) Molecular imaging in living subjects: Seeing fundamental biological processes in a new light. Genes Dev 17, 545-580
-
(2003)
Genes Dev
, vol.17
, pp. 545-580
-
-
Massoud, T.F.1
Gambhir, S.S.2
-
140
-
-
0242695030
-
Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging
-
Choy, G. et al. (2003) Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging. Biotechniques 35, 1022-1030
-
(2003)
Biotechniques
, vol.35
, pp. 1022-1030
-
-
Choy, G.1
-
141
-
-
27644594424
-
A luciferase transgenic mouse model: Visualization of prostate development and its androgen responsiveness in live animals
-
Hsieh, C.L. et al. (2005) A luciferase transgenic mouse model: visualization of prostate development and its androgen responsiveness in live animals. J Mol Endocrinol 35, 293-304
-
(2005)
J Mol Endocrinol
, vol.35
, pp. 293-304
-
-
Hsieh, C.L.1
-
142
-
-
33646398850
-
Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice
-
Lyons, S.K. et al. (2006) Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice. Cancer Res 66, 4701-4707
-
(2006)
Cancer Res
, vol.66
, pp. 4701-4707
-
-
Lyons, S.K.1
-
143
-
-
33751302596
-
Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens
-
Ellwood-Yen, K., Wongvipat, J. and Sawyers, C. (2006) Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens. Cancer Res 66, 10513-10516
-
(2006)
Cancer Res
, vol.66
, pp. 10513-10516
-
-
Ellwood-Yen, K.1
Wongvipat, J.2
Sawyers, C.3
-
144
-
-
34547632147
-
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence
-
Liao, C.P. et al. (2007) Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer Res 67, 7525-7533
-
(2007)
Cancer Res
, vol.67
, pp. 7525-7533
-
-
Liao, C.P.1
-
145
-
-
34547850622
-
In vivo MRI volumetric measurement of prostate regression and growth in mice
-
Nastiuk, K.L. et al. (2007) In vivo MRI volumetric measurement of prostate regression and growth in mice. BMC Urol 7, 12
-
(2007)
BMC Urol
, vol.7
, pp. 12
-
-
Nastiuk, K.L.1
-
146
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
Feil, R. et al. (1996) Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A 93, 10887-10890
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
-
147
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
-
Indra, A.K. et al. (1999) Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 27, 4324-4327
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4324-4327
-
-
Indra, A.K.1
-
148
-
-
0036549015
-
Conditional mouse models of sporadic cancer
-
Jonkers, J. and Berns, A. (2002) Conditional mouse models of sporadic cancer. Nat Rev Cancer 2, 251-265
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 251-265
-
-
Jonkers, J.1
Berns, A.2
-
149
-
-
0036895090
-
Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination
-
Bex, A. et al. (2002) Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination. J Urol 168, 2641-2644
-
(2002)
J Urol
, vol.168
, pp. 2641-2644
-
-
Bex, A.1
-
150
-
-
24944472212
-
Novel method of generating prostate-specific Cre-LoxP gene switching via intraductal delivery of adenovirus
-
Leow, C.C., Wang, X.D. and Gao, W.Q. (2005) Novel method of generating prostate-specific Cre-LoxP gene switching via intraductal delivery of adenovirus. Prostate 65, 1-9
-
(2005)
Prostate
, vol.65
, pp. 1-9
-
-
Leow, C.C.1
Wang, X.D.2
Gao, W.Q.3
-
151
-
-
0642303887
-
Inducible shRNA expression for application in a prostate cancer mouse model
-
Czauderna, F. et al. (2003) Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res 31, e127
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Czauderna, F.1
-
152
-
-
2342617500
-
Monitoring of therapy in androgen-dependent prostate tumor model by measuring tumor proliferation
-
Oyama, N. et al. (2004) Monitoring of therapy in androgen-dependent prostate tumor model by measuring tumor proliferation. J Nucl Med 45, 519-525
-
(2004)
J Nucl Med
, vol.45
, pp. 519-525
-
-
Oyama, N.1
-
153
-
-
33646050623
-
Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma
-
Yang, Y.S. et al. (2006) Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma. Nucl Med Biol 33, 371-380
-
(2006)
Nucl Med Biol
, vol.33
, pp. 371-380
-
-
Yang, Y.S.1
-
154
-
-
34547730701
-
In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: Side-by-side comparison of the CB-TE2A and DOTA chelation systems
-
Garrison, J.C. et al. (2007) In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: side-by-side comparison of the CB-TE2A and DOTA chelation systems. J Nucl Med 48, 1327-1337
-
(2007)
J Nucl Med
, vol.48
, pp. 1327-1337
-
-
Garrison, J.C.1
-
155
-
-
0842288323
-
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
-
Bhowmick, N.A. et al. (2004) TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303, 848-851
-
(2004)
Science
, vol.303
, pp. 848-851
-
-
Bhowmick, N.A.1
-
156
-
-
34547165661
-
Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer
-
Zhao, M. et al. (2007) Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer. Proc Natl Acad Sci U S A 104, 10170-10174
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10170-10174
-
-
Zhao, M.1
-
157
-
-
34250857547
-
Intratumoral delivery and suppression of prostate tumor growth by attenuated Salmonella enterica serovar typhimurium carrying plasmid-based small interfering RNAs
-
Zhang, L. et al. (2007) Intratumoral delivery and suppression of prostate tumor growth by attenuated Salmonella enterica serovar typhimurium carrying plasmid-based small interfering RNAs. Cancer Res 67, 5859-5864
-
(2007)
Cancer Res
, vol.67
, pp. 5859-5864
-
-
Zhang, L.1
|