Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

Journal of Cell Science

Volumn 115, Issue 1, 2002, Pages 39-50

  Gudjonsson, Thorarinn ^a   Rønnov Jessen, Lone ^a   Villadsen, René ^a   Rank, Fritz ^a   Bissell, Mina J ^a   Petersen, Ole William ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Breast cancer; Laminin; Morphogenesis; Myoepithelial function; Polarity; Reversion

Indexed keywords

ANTIGEN; BETA4 INTEGRIN; COLLAGEN TYPE 1; KALININ; LAMININ 1; OCCLUDIN; SIALOMUCIN;

ARTICLE; BASEMENT MEMBRANE; BREAST BIOPSY; BREAST CANCER; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CELL CULTURE; CELL INTERACTION; CELL ISOLATION; CELL POLARITY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MYOEPITHELIUM CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PURIFICATION; SAMPLE; STAINING;

BASEMENT MEMBRANE; BIOLOGICAL MARKERS; BREAST; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELL DIFFERENTIATION; CELL POLARITY; COLLAGEN; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GELS; HUMANS; IMMUNOHISTOCHEMISTRY; LAMININ; MICROSCOPY, CONFOCAL; TUMOR CELLS, CULTURED;

EID: 0036153330     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. Basement membrane changes in breast cancer detected by immunohistochemical staining for laminin
2. Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements
3. Differentiation of breast cancer cells in vitro is promoted by the concurrent influence of myoepithelial cells and relaxin
4. Long-term cultivation of a human breast cancer cell line, MCF-7, in a chemically defined medium. Effect of estradiol
5. An immunomagnetic separation method using superparamagnetic (MACS) beads for large-scale purification of human mammary luminal and myoepithelial cells
6. Form and function: The laminin family of heterodimers
7. Inhibition of laminin alpha 1-chain expression leads to alteration of basement membrane assembly and cell differentiation
8. Basal lamina formation by epithelial cell lines correlates with laminin A chain synthesis and secretion
9. Laminin isoforms and epithelial development
10. Distribution and isolation of four laminin variants: Tissue restricted distribution of heterotrimers assembled from five different subunits
11. Mapping of domains in human laminin using monoclonal antibodies: Localisation of the neurite-promoting site
12. Merosin promotes cell attachment and neurite outgrowth and is a component of the neurite-promoting factor of RN22 schwannoma cells
13. Identification of laminin-10/11 as a strong cell adhesive complex for a normal and a malignant human epithelial cell line
14. Human mammary gland morphogenesis in vitro: The growth and differentiation of normal breast epithelium in collagen gel cultures defined by electron microscopy, monoclonal antibodies and autoradiography
15. Isolation of pure populations of epithelial and myoepithelial cells from the normal human mammary gland using immunomagnetic separation with dynabeads
16. Separated human breast epithelial and myoepithelial cells have different growth factor requirements in vitro but can reconstitute normal breast lobuloalveolar structure
17. Ultrastructure of medullary, intraductal, tubular and adenocystic breast carcinomas. Comparative patterns of myoepithelial differentiation and basal lamina deposition
18. Generation and maintanance of epithelial cell polarity
19. Distribution of myoepithelial cells and basement membrane proteins in the normal breast and in benign and malignant breast diseases
20. Morphogenesis of mouse mammary epithelial cells growing within collagen gels: Ultrastructural and immunocytochemical characterization
21. Findings of myoepithelial cells in human breast cancer. Ultrastructural and immunohistochemical study by means of anti-myosin antibody
22. Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differentiation potential
23. Alteration of stromal protein and integrin expression in breast-a marker of premalignant change?
24. Maintenance of polarity and dual cell population in adenoid cystic carcinoma of the breast: An immunohistochemical study
25. Humatrix, a novel myoepithelial matrical gel with unique biochemical and biological properties
26. Morphologically stable epithelial vesicles cultured from normal human endometrium in defined media
27. Polarity and differentiation of human rectal adenocarcinoma cells in suspension and collagen gel cultures
28. Role of laminin A chain in the development of epithelial cell polarity
29. Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
30. Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells
31. Stem cells in breast epithelia
32. Inhibitory effects of activin on the growth and morphogenesis of primary and transformed mammary epithelial cells
33. Omission of histological grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: Results from a nationwide study
34. Comparative analysis of the distribution of laminin chains in the basement membranes in some malignant epithelial tumors: The alpha1 chain of laminin shows a selected expression pattern in human carcinomas
35. Biological and prognostic significance of stratified epithelial cytokeratins in infiltrating ductal breast carcinomas
36. Down-regulation of laminin-5 in breast carcinoma cells
37. Factors affecting morphogenesis of rabbit gall bladder epithelial cells cultured in collagen gels
38. The potential for oxytocin (OT) to prevent breast cancer: A hypothesis
39. The induction of smooth muscle α actin in a transformed rat cell line suppresses malignant properties in vitro and in vivo
40. Characterization of a monoclonal antibody (BG3C8) that reacts with basal cells of stratified epithelia
41. Human mammary luminal epithelial cells contain progenitors to myoepithelial cells
42. Preservation of defined phenotypic traits in short-time cultured human breast carcinoma derived epithelial cells
43. Growth factor control of myoepithelial-cell differentiation in cultures of human mammary gland
44. Differential tumorigenecity of two autologous human breast carcinoma cell lines HMT-3909 S1 and HMT-3909 S8 established in serum-free medium
45. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
46. Precocious mammary gland development in P-cadherin-deficient mice
47. Induction of α-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia
48. A fibroblast-associated antigen: Characterization in fibroblasts and immunoreactivity in smooth muscle differentiated stromal cells
49. Cellular changes involved in conversion of normal to malignant breast: The importance of the stromal reaction
50. Kalinin: An epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments
51. Stem cells and the development of mammary cancers in experimental rats and humans
52. Identification by differential display of alpha 6 integrin as a candidate tumor suppressor gene
53. Laminin A chains in developing tooth
54. Immunohistochemical detection of keratin, actin and type IV collagen in serial sections of methacarn-fixed breast cancer tissues
55. The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading and migration
56. The human myoepithelial cell exerts antiproliferative effects on breast carcinoma cells characterized by p21WAF1/CIP1 induction, G2/M arrest, and apoptosis
57. The human mammary gland basement membrane is integral to the polarity of luminal epithelial cells
58. Hepatocyte growth factor stimulates extensive development of branching duct-like stuctures by cloned mammary gland epithelial cells
59. The human myoepithelial cell is a natural tumor suppressor
60. Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
61. Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity
62. Reconstruction of alveolus-like structure from alveolar type II epithelial cells in three-dimensional collagen gel matrix culture
63. High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization
64. Presence of laminin α5 chain and lack of α1 chain during human muscle development and in muscular dystrophies
65. Filament disassembly and loss of mammary myoepithelial cells after exposure to λ-carrageenan
66. Laminins: Structure and genetic regulation
67. Epithelial membrane polarity: A stable differentiated feature of an established human breast carcinoma cell line MCF-7
68. Laminin α1-chain shows a restricted distribution in epithelial basement membranes of fetal and adult human tissues
69. Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland
70. Detection of basement membrane components and basal cell keratin 14 in noninvasuive and invasive carcinomas of the breast
71. Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells
72. Extracellular matrix components regulating glandular differentiation and the formation of basal lamina of a human pancreatic cancer cell line in vitro
73. Suppression of tumor-forming ability and related traits in MCF-7 human breast cancer cells by fusion with immortal mammary epithelial cells
74. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells