Pheromone response, mating and cell biology

Current Opinion in Microbiology

Volumn 3, Issue 6, 2000, Pages 573-581

  Elion, Elaine A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE;

ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MORPHOGENESIS; NONHUMAN; REVIEW; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; YEAST;

SACCHAROMYCES CEREVISIAE;

EID: 0033647489     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(00)00143-0     Document Type: Review

References (70)

1. Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae
2. The pathway of cell and nuclear fusion during mating in S. cerevisiae
3. MAP kinase pathways in the yeast Saccharomyces cerevisiae
4. The riddle of MAP kinase signaling specificity
5. Relative dependence of different outputs of the S. cerevisiae pheromone response pathway on the MAP kinase Fus3p
6. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
7. The HOG1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae
8. The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
9. Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast
10. Pheromone signalling and polarized morphogenesis in yeast
11. Gettin' down with ubiquitin: Turning off cell-surface receptors, transporters and channels
12. G-protein-coupled receptors function as oligomers in vivo
13. The C-terminus of the Saccharomyces cerevisiae α-factor receptor contributes to the formation of preactivation complexes with its cognate G protein
14. Signal transduction by a nondissociable heterotrimeric yeast G protein
15. Dual lipid modification of the yeast G gamma subunit Ste18p determines membrane localization of Gβγ
16. Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae
17. Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae
18. Genetic selection of peptide inhibitors of biological pathways
19. Routing MAP kinase cascades
20. Characterization of Fus3 localization: Active Fus3 localizes in complexes of varying size and specific activity
21. Signal transduction: Hanging on a scaffold
22. Reconstitution of a yeast protein kinase cascade in vitro. Activation of yeast MEK homolog Ste7 by Ste11
23. Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase
24. Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo
25. Protein kinases. Regulation by autoinhibitory domains
26. Multiple regulatory domains on the Byr2 protein kinase
27. Functional binding between G-beta and the LIM domain of Ste5 is required to activate the MEKK Ste11
28. The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae
29. Hsp90 is required for pheromone signaling in yeast
30. The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest
31. The Sch9 protein kinase regulates Hsp90 chaperone complex signal transduction activity in vivo
32. Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases
33. Ste5 RING-H2 domain-Role in Ste4-promoted oligomerization for yeast pheromone signaling
34. Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G-beta-gamma complex underlies activation of the yeast pheromone response pathway
35. Mapping of a yeast G protein by signaling interaction
36. Dimerization of Ste5, a mitogen-activated kinase cascade scaffold, is required for signal transduction
37. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
38. Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
39. The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf
40. Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade
41. The ins and outs of cell-polarity decisions
42. Responding to attraction: Chemotaxis and chemotropism in Dictyostelium and yeast
43. Cell polarity in yeast
44. Mid2 is a putative sensor for cell integrity signaling in Saccharomyces
45. Saccharomyces cerevisiae Mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway
46. G proteins mediate changes in cell shape by stabilizing the axis of polarity
47. The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating
48. A GTP-exchange factor required for cell orientation
49. A Cdc24p-Far1p-G beta gamma protein complex required for yeast orientation during mating
50. Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating
51. Nucleocytoplasmic shuttling of the Cdc42p exchange factor Cdc24p
52. A role for the actin cytoskeleton in pheromone receptor clustering and signalling
53. The guanine-nucleotide-exchange factor Cdc24p is targeted to the nucleus and polarized growth sites
54. Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p
55. Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast
56. MAP kinase signaling induces nuclear reorganization in budding yeast
57. A nucleolar protein that affects mating efficiency in Saccharomyces
58. Net results of nucleolar dynamics
59. Functional analysis of the interaction between Afr1p and Cdc12p septin, two proteins involved in pheromone- Induced morphogenesis
60. Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast
61. Monoubiquitin carries a novel internalization signal that is appended to activated receptors
62. Visualization of receptor-mediated endocytosis in yeast
63. The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex
64. A role for myosin-l in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex
65. Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization
66. The phosphorylation site for Ste20p-like protein kinases is essential for the function of myosin-l in yeast
67. Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway
68. Homo-oligomeric complexes of the yeast α-factor pheromone receptor are functional units of endocytosis
69. Mutational analysis suggests that activation of the yeast pheromone response MAPK pathway involves conformational changes in the Ste5 scaffold protein
70. Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae