Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 17, 1999, Pages 9539-9544

  Mukhopadhyay, S ^a   Ross, E M ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; MUSCARINIC RECEPTOR; PHOSPHOLIPASE C; REGULATOR PROTEIN;

ARTICLE; CATALYSIS; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CATALYSIS; ESCHERICHIA COLI; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEINS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; ISOENZYMES; KINETICS; PHOSPHOLIPASE C; PROTEIN FOLDING; PROTEINS; RGS PROTEINS; SPODOPTERA;

EID: 0033578385     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.17.9539     Document Type: Article

References (31)

1. Dohlman, H. G., Song, J. P., Ma, D. R., Courchesne, W. E. & Thorner, J. (1996) Mol. Cell. Biol. 16, 5194-5209.
2. Koelle, M. R. & Horvitz, H. R. (1996) Cell 84, 115-125.
3. Wieser, J., Yu, J.-H. & Adams, T. H. (1997) Curr. Genet. 32, 218-224.
4. Zerangue, N. & Jan, L. Y. (1998) Curr. Biol. 8, 313-316.
5. Dohlman, H. G. & Thorner, J. (1997) J. Biol. Chem. 272, 3871-3874.
6. Berman, D. M. & Gilman, A. G. (1998) J. Biol. Chem. 273, 1269-1272.
7. Arshavsky, V. Y. & Pugh, E. N., Jr. (1998) Neuron 20, 11-14.
8. Doupnik, C. A., Davidson, N., Lester, H. A. & Kofuji, P. (1997) Proc. Natl. Acad. Sci. USA 94, 10461-10466.
9. Saitoh, O., Kubo, Y., Miyatani, Y., Asano, T. & Nakata, H. (1997) Nature (London) 390, 525-529.
10. Chuang, H.-H., Yu, M., Jan, Y. N. & Jan, L. Y. (1998) Proc. Natl. Acad. Sci. USA 95, 11727-11732.
11. Bünemann, M. & Hosey, M. M. (1998) J. Biol. Chem. 273, 31186-31190.
12. Berstein, G., Blank, J. L., Jhon, D.-Y., Exton, J. H., Rhee, S. G. & Ross, E. M. (1992) Cell 70, 411-418.
13. Hart, M. J., Jiang, X., Kozasa, T., Roscoe, W., Singer, W. D., Gilman, A. G., Sternweis, P. C. & Bollag, G. (1998) Science 280, 2112-2114.
14. Kozasa, T., Jiang, X., Hart, M. J., Sternweis, P. M., Singer, W. D., Gilman, A. G., Bollag, G. & Sternweis, P. C. (1998) Science 280, 2109-2111.
15. Scholich, K., Mullenix, J. B., Wittpoth, C., Poppleton, H. M., Pierre, S. C., Lindorfer, M. A., Garrison, J. C. & Patel, T. B. (1999) Science 283, 1328-1331.
16. Breitwieser, G. E. & Szabo, G. (1988) J. Gen. Physiol. 91, 469-493.
17. He, W., Cowan, C. W. & Wensel, T. G. (1998) Neuron 20, 95-102.
18. Biddlecome, G. H., Berstein, G. & Ross, E. M. (1996) J. Biol. Chem. 271, 7999-8007.
19. Berstein, G., Blank, J. L., Smrcka, A. V., Higashijima, T., Sternweis, P. C., Exton, J. H. & Ross, E. M. (1992) J. Biol. Chem. 267, 8081-8088.
20. Berman, D. M., Wilkie, T. M. & Gilman, A. G. (1996) Cell 86, 445-452.
21. Brandt, D. R. & Ross, E. M. (1986) J. Biol. Chem. 261, 1656-1664.
22. Chidiac, P., Markin, V. S. & Ross, E. M. (1999) Biochem. Pharmacol. 58, 39-48.
23. Gideon, P., John, J., Frech, M., Lautwein, A., Clark, R., Scheffler, J. E. & Wittinghofer, A. (1992) Mol. Cell. Biol. 12, 2050-2056.
24. Scheffzek, K., Ahmadian, M. R., Kabsch, W., Wiesmüller, L., Lautwein, A., Schmitz, F. & Wittinghofer, A. (1998) Science 277, 333-338.
25. Ranganathan, R., Harris, G. L., Stevens, C. F. & Zuker, C. S. (1991) Nature (London) 354, 230-232.
26. Wang, J., Ducret, A., Tu, Y., Kozasa, T., Aebersold, R. & Ross, E. M. (1998) J. Biol. Chem. 273, 26014-26025.
27. Nekrasova, E. R., Berman, D. M., Rustandi, R. R., Hamm, H. E., Gilman, A. G. & Arshavsky, V. Y. (1997) Biochemistry 36, 7638-7643.
28. Posner, B. A., Mukhopadhyay, S., Tesmer, J. J., Gilman, A. G. & Ross, E. M. (1999) Biochemistry 38, 7773-7779.
29. Chidiac, P. & Ross, E. M. (1999) J. Biol. Chem. 274, 19639-19643.
30. Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., et al. (1998) J. Neurosci. 18, 7178-7188.
31. Traut, T. W. (1994) Mol. Cell. Biochem. 140, 1-22.