메뉴 건너뛰기




Volumn 9, Issue 1, 2004, Pages 39-53

Transcriptional control of the cell cycle in mammary gland development and tumorigenesis

Author keywords

Breast cancer; Cell cycle control; Ets; Homeobox genes; Id; Mammary gland development; Proliferation; Six family; STAT; Transcription factors

Indexed keywords

BRCA1 PROTEIN; HOMEODOMAIN PROTEIN; HOX PROTEIN; STAT PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; STAT5 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR ETS 2; TRANSCRIPTION FACTOR PAX2;

EID: 4344686178     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOMG.0000023587.40966.f6     Document Type: Review
Times cited : (35)

References (118)
  • 1
    • 0034468329 scopus 로고    scopus 로고
    • Homeobox genes in mammary gland development and neoplasia
    • M. T. Lewis (2000). Homeobox genes in mammary gland development and neoplasia. Breast Cancer Res. 2:158-169.
    • (2000) Breast Cancer Res. , vol.2 , pp. 158-169
    • Lewis, M.T.1
  • 2
    • 0038561099 scopus 로고    scopus 로고
    • Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina
    • M. A. Dyer, F. J. Livesey, C. L. Cepko, and G. Oliver (2003). Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat. Genet. 34:53-58.
    • (2003) Nat. Genet. , vol.34 , pp. 53-58
    • Dyer, M.A.1    Livesey, F.J.2    Cepko, C.L.3    Oliver, G.4
  • 3
    • 0036782277 scopus 로고    scopus 로고
    • Deregulated homeobox gene expression in cancer: Cause or consequence?
    • C. Abate-Shen (2002). Deregulated homeobox gene expression in cancer: Cause or consequence? Nat. Rev. Cancer 2:777-785.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 777-785
    • Abate-Shen, C.1
  • 7
    • 0036569798 scopus 로고    scopus 로고
    • Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia
    • A. W. Ledford, J. G. Brantley, G. Kemeny, T. L. Foreman, S. E. Quaggin, P. Igarashi, S. M. Oberhaus, M. Rodova, J. P. Calvet, and G. B. Vanden Heuvel (2002). Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia. Dev. Biol. 245:157-171.
    • (2002) Dev. Biol. , vol.245 , pp. 157-171
    • Ledford, A.W.1    Brantley, J.G.2    Kemeny, G.3    Foreman, T.L.4    Quaggin, S.E.5    Igarashi, P.6    Oberhaus, S.M.7    Rodova, M.8    Calvet, J.P.9    Vanden Heuvel, G.B.10
  • 8
    • 0032419148 scopus 로고    scopus 로고
    • Homeobox genes: A link between development, cell cycle, and cancer?
    • H. L. Ford (1998). Homeobox genes: A link between development, cell cycle, and cancer? Cell Biol. Int. 22:397-400.
    • (1998) Cell Biol. Int. , vol.22 , pp. 397-400
    • Ford, H.L.1
  • 9
    • 0035865250 scopus 로고    scopus 로고
    • Expressing the human genome
    • R. Tupler, G. Perini, and M. R. Green (2001). Expressing the human genome. Nature 409:832-833.
    • (2001) Nature , vol.409 , pp. 832-833
    • Tupler, R.1    Perini, G.2    Green, M.R.3
  • 11
    • 0033924215 scopus 로고    scopus 로고
    • Six family genes - Structure and function as transcription factors and their roles in development
    • K. Kawakami, S. Sato, H. Ozaki, and K. Ikeda (2000). Six family genes - Structure and function as transcription factors and their roles in development. Bioessays 22:616-626.
    • (2000) Bioessays , vol.22
    • Kawakami, K.1    Sato, S.2    Ozaki, H.3    Ikeda, K.4
  • 12
    • 0034667988 scopus 로고    scopus 로고
    • p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells
    • V. C. Bromleigh and L. P. Freedman (2000). p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes Dev. 14:2581-2586.
    • (2000) Genes Dev. , vol.14 , pp. 2581-2586
    • Bromleigh, V.C.1    Freedman, L.P.2
  • 16
    • 0031031397 scopus 로고    scopus 로고
    • HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint
    • T. Kawabe, A. J. Muslin, and S. J. Korsmeyer (1997). HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint. Nature 385:454-458.
    • (1997) Nature , vol.385 , pp. 454-458
    • Kawabe, T.1    Muslin, A.J.2    Korsmeyer, S.J.3
  • 17
    • 0029091352 scopus 로고
    • Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation
    • D. L. Rossi, A. Acebron, and P. Santisteban (1995). Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation. J. Biol. Chem. 270:23139-23142.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23139-23142
    • Rossi, D.L.1    Acebron, A.2    Santisteban, P.3
  • 19
    • 0032474748 scopus 로고    scopus 로고
    • Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1
    • J. Krosl, S. Baban, G. Krosl, S. Rozenfeld, C, and G. Sauvageau (1998). Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1. Oncogene 16:3403-3412.
    • (1998) Oncogene , vol.16 , pp. 3403-3412
    • Krosl, J.1    Baban, S.2    Krosl, G.3    Rozenfeld, S.4    Sauvageau, C.5    Sauvageau, G.6
  • 20
    • 0033555425 scopus 로고    scopus 로고
    • Msx2 gene dosage influences the number of proliferative osteogenic cells in growth centers of the developing murine skull: A possible mechanism for MSX2-mediated craniosynostosis in humans
    • Y. H. Liu, Z. Tang, R. K. Kundu, L. Wu, W. Luo, D. Zhu, F. Sangiorgi, M. L. Snead, and R. E. Maxson (1999). Msx2 gene dosage influences the number of proliferative osteogenic cells in growth centers of the developing murine skull: A possible mechanism for MSX2-mediated craniosynostosis in humans. Dev. Biol. 205:260-274.
    • (1999) Dev. Biol. , vol.205 , pp. 260-274
    • Liu, Y.H.1    Tang, Z.2    Kundu, R.K.3    Wu, L.4    Luo, W.5    Zhu, D.6    Sangiorgi, F.7    Snead, M.L.8    Maxson, R.E.9
  • 21
    • 0031691193 scopus 로고    scopus 로고
    • Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish
    • M. Kobayashi, R. Toyama, H. Takeda, I. B. Dawid, and K. Kawakami (1998). Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish. Development 125:2973-2982.
    • (1998) Development , vol.125 , pp. 2973-2982
    • Kobayashi, M.1    Toyama, R.2    Takeda, H.3    Dawid, I.B.4    Kawakami, K.5
  • 22
    • 0037172981 scopus 로고    scopus 로고
    • Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype
    • G. Goudreau, P. Perron, L. W. Reneker, J. Graw, J. Loster, and P. Gruss (2002). Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype. Proc. Natl. Acad. Sci. U.S.A. 99:8719-8724.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 8719-8724
    • Goudreau, G.1    Perron, P.2    Reneker, L.W.3    Graw, J.4    Loster, J.5    Gruss, P.6
  • 23
    • 0032514597 scopus 로고    scopus 로고
    • Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis
    • H. L. Ford, E. N. Kabingu, E. A. Bump, G. L. Mutter, and A. B. Pardee (1998). Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis. Proc. Natl. Acad. Sci. U.S.A. 95:12608-12613.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 12608-12613
    • Ford, H.L.1    Kabingu, E.N.2    Bump, E.A.3    Mutter, G.L.4    Pardee, A.B.5
  • 24
    • 0033256231 scopus 로고    scopus 로고
    • Cancer and the cell cycle
    • H. L. Ford, and A. B. Pardee (1999). Cancer and the cell cycle. J. Cell Biochem. (Suppl.) 32/33:166-172.
    • (1999) J. Cell Biochem. , vol.32-33 , Issue.SUPPL. , pp. 166-172
    • Ford, H.L.1    Pardee, A.B.2
  • 25
    • 0041326752 scopus 로고    scopus 로고
    • The role of Six1 in mammalian auditory system development
    • W. Zheng, L. Huang, Z. B. Wei, D. Silvius, B. Tang, and P. X. Xu (2003). The role of Six1 in mammalian auditory system development. Development 130:3989-4000.
    • (2003) Development , vol.130 , pp. 3989-4000
    • Zheng, W.1    Huang, L.2    Wei, Z.B.3    Silvius, D.4    Tang, B.5    Xu, P.X.6
  • 27
    • 0037119585 scopus 로고    scopus 로고
    • Tissue-specific regulation of retinal and pituitary precursor cell proliferation
    • X. Li, V. Perissi, F. Liu, D. W. Rose, and M. G. Rosenfeld (2002). Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science 297:1180-1183.
    • (2002) Science , vol.297 , pp. 1180-1183
    • Li, X.1    Perissi, V.2    Liu, F.3    Rose, D.W.4    Rosenfeld, M.G.5
  • 29
    • 0034635456 scopus 로고    scopus 로고
    • The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins
    • J. Lynch, E. R. Suh, D. G. Silberg, S. Rulyak, N. Blanchard, and P. G. Traber (2000). The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins. J. Biol. Chem. 275:4499-4506.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4499-4506
    • Lynch, J.1    Suh, E.R.2    Silberg, D.G.3    Rulyak, S.4    Blanchard, N.5    Traber, P.G.6
  • 32
    • 0038299546 scopus 로고    scopus 로고
    • Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton
    • D. M. Wellik and M. R. Capecchi (2003). Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science 301:363-367.
    • (2003) Science , vol.301 , pp. 363-367
    • Wellik, D.M.1    Capecchi, M.R.2
  • 33
    • 1642564381 scopus 로고    scopus 로고
    • Role of homeobox genes in normal mammary gland development and breast Tumorigenesis
    • H. Chen and S. Sukumar (2003). Role of homeobox genes in normal mammary gland development and breast Tumorigenesis. J. Mammary Gland Biol. Neoplasia 21:157-174.
    • (2003) J. Mammary Gland Biol. Neoplasia , vol.21 , pp. 157-174
    • Chen, H.1    Sukumar, S.2
  • 34
    • 0000336513 scopus 로고    scopus 로고
    • Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy
    • F. Chen and M. R. Capecchi (1999). Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy. Proc. Natl. Acad. Sci. U.S.A 96:541-546.
    • (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 541-546
    • Chen, F.1    Capecchi, M.R.2
  • 36
    • 0028043991 scopus 로고
    • Hox genes in normal and neoplastic mouse mammary gland
    • Y. Friedmann, C. A. Daniel, P. Strickland, and C. W. Daniel (1994). Hox genes in normal and neoplastic mouse mammary gland. Cancer Res. 54:5981-5985.
    • (1994) Cancer Res. , vol.54 , pp. 5981-5985
    • Friedmann, Y.1    Daniel, C.A.2    Strickland, P.3    Daniel, C.W.4
  • 37
    • 0031780234 scopus 로고    scopus 로고
    • Expression of Hoxa-1 and Hoxb-7 is regulated by extracellular matrix-dependent signals in mammary epithelial cells
    • A. Srebrow, Y. Friedmann, A. Ravanpay, C. W. Daniel, and M. J. Bissell (1998). Expression of Hoxa-1 and Hoxb-7 is regulated by extracellular matrix-dependent signals in mammary epithelial cells. J. Cell Biochem. 69:377-391.
    • (1998) J. Cell Biochem. , vol.69 , pp. 377-391
    • Srebrow, A.1    Friedmann, Y.2    Ravanpay, A.3    Daniel, C.W.4    Bissell, M.J.5
  • 39
    • 0032566065 scopus 로고    scopus 로고
    • Transduction of the SkBr3 breast carcinoma cell line with the HOXB7 gene induces bFGF expression, increases cell proliferation and reduces growth factor dependence
    • A. Care, A. Silvani, E. Meccia, G. Mattia, C. Peschle, and M. P. Colombo (1998). Transduction of the SkBr3 breast carcinoma cell line with the HOXB7 gene induces bFGF expression, increases cell proliferation and reduces growth factor dependence. Oncogene 16:3285-3289.
    • (1998) Oncogene , vol.16 , pp. 3285-3289
    • Care, A.1    Silvani, A.2    Meccia, E.3    Mattia, G.4    Peschle, C.5    Colombo, M.P.6
  • 40
    • 0033580392 scopus 로고    scopus 로고
    • Enforced expression of HOXB7 promotes hematopoietic stem cell proliferation and myeloid-restricted progenitor differentiation
    • A. Care, M. Valtieri, G. Mattia, E. Meccia, B. Masella, L. Luchetti, F. Felicetti, M. P. Colombo, and C. Peschle (1999). Enforced expression of HOXB7 promotes hematopoietic stem cell proliferation and myeloid-restricted progenitor differentiation. Oncogene 18:1993-2001.
    • (1999) Oncogene , vol.18 , pp. 1993-2001
    • Care, A.1    Valtieri, M.2    Mattia, G.3    Meccia, E.4    Masella, B.5    Luchetti, L.6    Felicetti, F.7    Colombo, M.P.8    Peschle, C.9
  • 45
    • 0032825495 scopus 로고    scopus 로고
    • Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya
    • H. Ohto, S. Kamada, K. Tago, S. I. Tominaga, H. Ozaki, S. Sato, and K. Kawakami (1999). Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. Mol. Cell Biol. 19:6815-6824.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 6815-6824
    • Ohto, H.1    Kamada, S.2    Tago, K.3    Tominaga, S.I.4    Ozaki, H.5    Sato, S.6    Kawakami, K.7
  • 46
    • 0033573001 scopus 로고    scopus 로고
    • From insect eye to vertebrate muscle: Redeployment of a regulatory network
    • F. Relaix and M. Buckingham (1999). From insect eye to vertebrate muscle: Redeployment of a regulatory network. Genes Dev. 13:3171-3178.
    • (1999) Genes Dev. , vol.13 , pp. 3171-3178
    • Relaix, F.1    Buckingham, M.2
  • 47
    • 0038016516 scopus 로고    scopus 로고
    • Thymus, kidney and craniofacial abnormalities in Six1 deficient mice
    • C. Laclef, E. Souil, J. Demignon, and P. Maire (2003). Thymus, kidney and craniofacial abnormalities in Six1 deficient mice. Mech. Dev. 120:669-679.
    • (2003) Mech. Dev. , vol.120 , pp. 669-679
    • Laclef, C.1    Souil, E.2    Demignon, J.3    Maire, P.4
  • 48
    • 0242636457 scopus 로고    scopus 로고
    • Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway
    • A. P. Young, R. Nagarajan, and G. D. Longmore (2003). Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene 22:7209-7217.
    • (2003) Oncogene , vol.22 , pp. 7209-7217
    • Young, A.P.1    Nagarajan, R.2    Longmore, G.D.3
  • 50
    • 0035956894 scopus 로고    scopus 로고
    • High-sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood
    • K. J. Martin, E. Graner, Y. Li, L. M. Price, B. M. Kritzman, M. V. Fournier, E. Rhei, and A. B. Pardee (2001). High-sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood. Proc. Natl. Acad. Sci. U.S.A. 98:2646-2651.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 2646-2651
    • Martin, K.J.1    Graner, E.2    Li, Y.3    Price, L.M.4    Kritzman, B.M.5    Fournier, M.V.6    Rhei, E.7    Pardee, A.B.8
  • 52
    • 0029164842 scopus 로고
    • The function and evolution of Msx genes: Pointers and paradoxes
    • D. Davidson (1995). The function and evolution of Msx genes: Pointers and paradoxes. Trends Genet 11:405-411.
    • (1995) Trends Genet , vol.11 , pp. 405-411
    • Davidson, D.1
  • 53
    • 0034932343 scopus 로고    scopus 로고
    • Msx homeobox genes inhibit differentiation through upregulation of cyclin D1
    • G. Hu, H. Lee, S. M. Price, M. M. Shen, and C. Abate-Shen (2001). Msx homeobox genes inhibit differentiation through upregulation of cyclin D1. Development 128:2373-2384.
    • (2001) Development , vol.128 , pp. 2373-2384
    • Hu, G.1    Lee, H.2    Price, S.M.3    Shen, M.M.4    Abate-Shen, C.5
  • 55
  • 56
    • 85047698743 scopus 로고    scopus 로고
    • Expression of the PAX2 oncogene in human breast cancer and its role in progesterone-dependent mammary growth
    • G. B. Silberstein, G. R. Dressler, and K. Van Horn (2002). Expression of the PAX2 oncogene in human breast cancer and its role in progesterone-dependent mammary growth. Oncogene 21:1009-1016.
    • (2002) Oncogene , vol.21 , pp. 1009-1016
    • Silberstein, G.B.1    Dressler, G.R.2    Van Horn, K.3
  • 57
    • 0035972762 scopus 로고    scopus 로고
    • Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development
    • A. Nepveu (2001). Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development. Gene 270:1-15.
    • (2001) Gene , vol.270 , pp. 1-15
    • Nepveu, A.1
  • 58
    • 0034469444 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development
    • J. Bromberg (2000). Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development. Breast. Cancer Res. 2:86-90.
    • (2000) Breast Cancer Res. , vol.2 , pp. 86-90
    • Bromberg, J.1
  • 59
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • J. Bromberg (2002). Stat proteins and oncogenesis. J. Clin. Invest. 109:1139-1142.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1139-1142
    • Bromberg, J.1
  • 60
    • 0035230599 scopus 로고    scopus 로고
    • Stat transcription factors in mammary gland development and tumorigenesis
    • C. J. Watson (2001). Stat transcription factors in mammary gland development and tumorigenesis. J. Mammary Gland Biol. Neoplasia 6:115-127.
    • (2001) J. Mammary Gland Biol. Neoplasia , vol.6 , pp. 115-127
    • Watson, C.J.1
  • 61
    • 0029906982 scopus 로고    scopus 로고
    • Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation
    • X. Liu, G. W. Robinson, and L. Hennighausen (1996). Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol. Endocrinol 10:1496-1506.
    • (1996) Mol. Endocrinol , vol.10 , pp. 1496-1506
    • Liu, X.1    Robinson, G.W.2    Hennighausen, L.3
  • 62
    • 0345700700 scopus 로고    scopus 로고
    • Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis
    • E. Iavnilovitch, B. Groner, and I. Barash (2002). Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis. Mol. Cancer Res. 1:32-47.
    • (2002) Mol. Cancer Res. , vol.1 , pp. 32-47
    • Iavnilovitch, E.1    Groner, B.2    Barash, I.3
  • 65
    • 0036793979 scopus 로고    scopus 로고
    • Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
    • A. Widschwendter, S. Tonko-Geymayer, T. Welte, G. Daxenbichler, C. Marth, and W. Doppler (2002). Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin. Cancer Res. 8:3065-3074.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3065-3074
    • Widschwendter, A.1    Tonko-Geymayer, S.2    Welte, T.3    Daxenbichler, G.4    Marth, C.5    Doppler, W.6
  • 66
    • 0037206950 scopus 로고    scopus 로고
    • Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
    • P. J. Real, A. Sierra, A. De Juan, J. C. Segovia, J. M. Lopez-Vega, and J. L. Fernandez-Luna (2002). Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene 21:7611-7618.
    • (2002) Oncogene , vol.21 , pp. 7611-7618
    • Real, P.J.1    Sierra, A.2    DeJuan, A.3    Segovia, J.C.4    Lopez-Vega, J.M.5    Fernandez-Luna, J.L.6
  • 67
    • 0037124102 scopus 로고    scopus 로고
    • Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines
    • L. Li and P. E. Shaw (2002). Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines. J. Biol. Chem. 277:17397-17405.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17397-17405
    • Li, L.1    Shaw, P.E.2
  • 69
    • 0037434666 scopus 로고    scopus 로고
    • Delineating an oncostatin M-activated STAT3 signaling pathway that coordinates the expression of genes involved in cell cycle regulation and extracellular matrix deposition of MCF-7 cells
    • F. Zhang, C. Li, H. Halfter, and J. Liu (2003). Delineating an oncostatin M-activated STAT3 signaling pathway that coordinates the expression of genes involved in cell cycle regulation and extracellular matrix deposition of MCF-7 cells. Oncogene 22:894-905.
    • (2003) Oncogene , vol.22 , pp. 894-905
    • Zhang, F.1    Li, C.2    Halfter, H.3    Liu, J.4
  • 70
    • 0037142617 scopus 로고    scopus 로고
    • Loss of Stat5a delays mammary cancer progression in a mouse model
    • S. Ren, H. R. Cai, M. Li, and P. A. Furth (2002). Loss of Stat5a delays mammary cancer progression in a mouse model. Oncogene 21:4335-4339.
    • (2002) Oncogene , vol.21 , pp. 4335-4339
    • Ren, S.1    Cai, H.R.2    Li, M.3    Furth, P.A.4
  • 71
    • 0037457078 scopus 로고    scopus 로고
    • Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
    • H. Yamashita, H. Iwase, T. Toyama, and Y. Fujii (2003). Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells. Oncogene 22:1638-1652.
    • (2003) Oncogene , vol.22 , pp. 1638-1652
    • Yamashita, H.1    Iwase, H.2    Toyama, T.3    Fujii, Y.4
  • 72
    • 0037448612 scopus 로고    scopus 로고
    • Molecular biology of the Ets family of transcription factors
    • T. Oikawa and T. Yamada (2003). Molecular biology of the Ets family of transcription factors. Gene 303:11-34.
    • (2003) Gene , vol.303 , pp. 11-34
    • Oikawa, T.1    Yamada, T.2
  • 73
    • 0035515347 scopus 로고    scopus 로고
    • The ETS-domain transcription factor family
    • A. D. Sharrocks (2001). The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2:827-237.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 237-827
    • Sharrocks, A.D.1
  • 74
    • 0034684619 scopus 로고    scopus 로고
    • Ets target genes: Past, present and future
    • V. I. Sementchenko and D. K. Watson (2000). Ets target genes: past, present and future. Oncogene 19:6533-6548.
    • (2000) Oncogene , vol.19 , pp. 6533-6548
    • Sementchenko, V.I.1    Watson, D.K.2
  • 75
    • 0038375546 scopus 로고    scopus 로고
    • CDK6 blocks differentiation: Coupling cell proliferation to the block to differentiation in leukemic cells
    • I. Matushansky, F. Radparvar, and A. I. Skoultchi (2003). CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells. Oncogene 22:4143-4149.
    • (2003) Oncogene , vol.22 , pp. 4143-4149
    • Matushansky, I.1    Radparvar, F.2    Skoultchi, A.I.3
  • 77
    • 0042346348 scopus 로고    scopus 로고
    • Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETs-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF1/Cip1 promoter
    • C. Zhang, M. M. Kavurma, A. Lai, and L. M. Khachigian (2003). Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETs-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF1/Cip1 promoter. J. Biol. Chem. 278:27903-27909.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27903-27909
    • Zhang, C.1    Kavurma, M.M.2    Lai, A.3    Khachigian, L.M.4
  • 78
    • 0035798672 scopus 로고    scopus 로고
    • Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle
    • Y. Miyazaki, P. Boccuni, S. Mao, J. Zhang, H. Erdjument-Bromage, P. Tempst, H. Kiyokawa, and S. D. Nimer (2001). Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle. J. Biol. Chem. 276:40528-40536.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40528-40536
    • Miyazaki, Y.1    Boccuni, P.2    Mao, S.3    Zhang, J.4    Erdjument-Bromage, H.5    Tempst, P.6    Kiyokawa, H.7    Nimer, S.D.8
  • 79
    • 0029095176 scopus 로고
    • ERF: An ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
    • D. N. Sgouras, M. A. Athanasiou, G. J. Beal, Jr., R. J. Fisher, D. G. Blair, and G. J. Mavrothalassitis (1995). ERF: An ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. EMBO J. 14:4781-4793.
    • (1995) EMBO J. , vol.14 , pp. 4781-4793
    • Sgouras, D.N.1    Athanasiou, M.A.2    Beal Jr., G.J.3    Fisher, R.J.4    Blair, D.G.5    Mavrothalassitis, G.J.6
  • 80
    • 0033050069 scopus 로고    scopus 로고
    • Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation
    • L. Le Gallic, D. Sgouras, G. Beal, Jr., and G. Mavrothalassitis (1999). Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation. Mol. Cell Biol. 19:4121-4133.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 4121-4133
    • Le Gallic, L.1    Sgouras, D.2    Beal Jr., G.3    Mavrothalassitis, G.4
  • 81
    • 0038642508 scopus 로고    scopus 로고
    • PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro
    • A. Chotteau-Lelievre, R. Montesano, J. Soriano, P. Soulie, X. Desbiens, and Y. de Launoit (2003). PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro. Dev. Biol. 259:241-257.
    • (2003) Dev. Biol. , vol.259 , pp. 241-257
    • Chotteau-Lelievre, A.1    Montesano, R.2    Soriano, J.3    Soulie, P.4    Desbiens, X.5    de Launoit, Y.6
  • 82
    • 0034684616 scopus 로고    scopus 로고
    • Expression and function of Ets transcription factors in mammalian development: A regulatory network
    • I. G. Maroulakou and D. B. Bowe (2000). Expression and function of Ets transcription factors in mammalian development: A regulatory network. Oncogene 19:6432-6442.
    • (2000) Oncogene , vol.19 , pp. 6432-6442
    • Maroulakou, I.G.1    Bowe, D.B.2
  • 83
    • 0034723354 scopus 로고    scopus 로고
    • ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1
    • K. Kas, E. Finger, F. Grall, X. Gu, Y. Akbarali, J. Boltax, A. Weiss, P. Oettgen, R. Kapeller, and T. A. Libermann (2000). ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1. J. Biol. Chem. 275:2986-2998.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2986-2998
    • Kas, K.1    Finger, E.2    Grall, F.3    Gu, X.4    Akbarali, Y.5    Boltax, J.6    Weiss, A.7    Oettgen, P.8    Kapeller, R.9    Libermann, T.A.10
  • 84
    • 0031765855 scopus 로고    scopus 로고
    • The epithelium-specific ets transcription factor ESX is associated with mammary gland development and involution
    • R. Neve, C. H. Chang, G. K. Scott, A. Wong, R. R. Friis, N. E. Hynes, and C. C. Benz (1998). The epithelium-specific ets transcription factor ESX is associated with mammary gland development and involution. FASEB. 112:1541-1550.
    • (1998) FASEB , vol.112 , pp. 1541-1550
    • Neve, R.1    Chang, C.H.2    Scott, G.K.3    Wong, A.4    Friis, R.R.5    Hynes, N.E.6    Benz, C.C.7
  • 85
    • 0032569891 scopus 로고    scopus 로고
    • A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines
    • J. Zhou, A. Y. Ng, M. J. Tymms, L. S. Jermiin, A. K. Seth, R. S. Thomas, and I. Kola (1998). A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines. Oncogene 17:2719-2732.
    • (1998) Oncogene , vol.17 , pp. 2719-2732
    • Zhou, J.1    Ng, A.Y.2    Tymms, M.J.3    Jermiin, L.S.4    Seth, A.K.5    Thomas, R.S.6    Kola, I.7
  • 87
    • 0035223187 scopus 로고    scopus 로고
    • Role of Ets transcription factors in mammary gland development and oncogenesis
    • T. Shepherd and J. A. Hassell (2001). Role of Ets transcription factors in mammary gland development and oncogenesis. J. Mammary Gland Biol. Neoplasia 6:129-140.
    • (2001) J. Mammary Gland Biol. Neoplasia , vol.6 , pp. 129-140
    • Shepherd, T.1    Hassell, J.A.2
  • 88
    • 0037028211 scopus 로고    scopus 로고
    • Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer
    • P. N. Span, P. Manders, J. J. Heuvel, C. M. Thomas, R. R. Bosch, L. V. Beex, and C. G. Sweep (2002). Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer. Oncogene 21:8506-8509.
    • (2002) Oncogene , vol.21 , pp. 8506-8509
    • Span, P.N.1    Manders, P.2    Heuvel, J.J.3    Thomas, C.M.4    Bosch, R.R.5    Beex, L.V.6    Sweep, C.G.7
  • 89
    • 0034802736 scopus 로고    scopus 로고
    • Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen
    • A. Ghadersohi, and A. K. Sood (2001). Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen. Clin. Cancer Res. 7:2731-2738.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2731-2738
    • Ghadersohi, A.1    Sood, A.K.2
  • 90
    • 0037128696 scopus 로고    scopus 로고
    • Prostate-Specific Ets (PSE) factor: A novel marker for detection of metastatic breast cancer in axillary lymph nodes
    • M. Mitas, K. Mikhitarian, L. Hoover, M. A. Lockett, L. Kelley, A. Hill, W. E. Gillanders, and D. J. Cole (2002). Prostate-Specific Ets (PSE) factor: A novel marker for detection of metastatic breast cancer in axillary lymph nodes. Br. J. Cancer 86:899-904.
    • (2002) Br. J. Cancer , vol.86 , pp. 899-904
    • Mitas, M.1    Mikhitarian, K.2    Hoover, L.3    Lockett, M.A.4    Kelley, L.5    Hill, A.6    Gillanders, W.E.7    Cole, D.J.8
  • 92
    • 0042635811 scopus 로고    scopus 로고
    • Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression
    • R. J. Feldman, V. I. Sementchenko, M. Gayed, M. M. Fraig, and D. K. Watson (2003). Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression. Cancer Res. 63:4626-4631.
    • (2003) Cancer Res. , vol.63 , pp. 4626-4631
    • Feldman, R.J.1    Sementchenko, V.I.2    Gayed, M.3    Fraig, M.M.4    Watson, D.K.5
  • 93
    • 0025638903 scopus 로고
    • The c-ets-1 proto-oncogene has oncogenic activity and is positively autoregulated
    • A. Seth and T. S. Papas (1990). The c-ets-1 proto-oncogene has oncogenic activity and is positively autoregulated. Oncogene 5:1761-1767.
    • (1990) Oncogene , vol.5 , pp. 1761-1767
    • Seth, A.1    Papas, T.S.2
  • 95
    • 0033602173 scopus 로고    scopus 로고
    • FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts
    • R. Pereira, C. T. Quang, I. Lesault, H. Dolznig, H. Beug, and J. Ghysdael (1999). FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts. Oncogene 18:1597-1608.
    • (1999) Oncogene , vol.18 , pp. 1597-1608
    • Pereira, R.1    Quang, C.T.2    Lesault, I.3    Dolznig, H.4    Beug, H.5    Ghysdael, J.6
  • 96
    • 0028932437 scopus 로고
    • Human ERG is a proto-oncogene with mitogenic and transforming activity
    • A. H. Hart, C. M. Corrick, M. J. Tymms, P. J. Hertzog, and I. Kola (1995). Human ERG is a proto-oncogene with mitogenic and transforming activity. Oncogene 10:1423-1430.
    • (1995) Oncogene , vol.10 , pp. 1423-1430
    • Hart, A.H.1    Corrick, C.M.2    Tymms, M.J.3    Hertzog, P.J.4    Kola, I.5
  • 98
    • 0032032593 scopus 로고    scopus 로고
    • Ets-2 transdominant mutant abolishes anchorage-independent growth and macrophage colony-stimulating factor-stimulated invasion by BT20 breast carcinoma cells
    • E. Sapi, M. B. Flick, S. Rodov, and B. M. Kacinski (1998). Ets-2 transdominant mutant abolishes anchorage-independent growth and macrophage colony-stimulating factor-stimulated invasion by BT20 breast carcinoma cells. Cancer Res. 58:1027-1033.
    • (1998) Cancer Res. , vol.58 , pp. 1027-1033
    • Sapi, E.1    Flick, M.B.2    Rodov, S.3    Kacinski, B.M.4
  • 99
    • 0031838477 scopus 로고    scopus 로고
    • The expression of an Ets1 transcription factor lacking its activation domain decreases uPA proteolytic activity and cell motility, and impairs normal tubulogenesis and cancerous scattering in mammary epithelial cells
    • A. Delannoy-Courdent, V. Mattot, V. Fafeur, W. Fauquette, I. Pollet, T. Calmels, C. Vercamer, B. Boilly, B. Vandenbunder, and X. Desbiens (1998). The expression of an Ets1 transcription factor lacking its activation domain decreases uPA proteolytic activity and cell motility, and impairs normal tubulogenesis and cancerous scattering in mammary epithelial cells. J. Cell Sci. 111(Pt. 11):1521-1534.
    • (1998) J. Cell Sci. , vol.111 , Issue.PART 11 , pp. 1521-1534
    • Delannoy-Courdent, A.1    Mattot, V.2    Fafeur, V.3    Fauquette, W.4    Pollet, I.5    Calmels, T.6    Vercamer, C.7    Boilly, B.8    Vandenbunder, B.9    Desbiens, X.10
  • 100
    • 0033199167 scopus 로고    scopus 로고
    • A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice
    • N. Neznanov, A. K. Man, H. Yamamoto, C. A. Hauser, R. D. Cardiff, and R. G. Oshima (1999). A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice. Cancer Res. 59:4242-4246.
    • (1999) Cancer Res. , vol.59 , pp. 4242-4246
    • Neznanov, N.1    Man, A.K.2    Yamamoto, H.3    Hauser, C.A.4    Cardiff, R.D.5    Oshima, R.G.6
  • 103
    • 0035924702 scopus 로고    scopus 로고
    • Id proteins at the cross-road of development and cancer
    • A. Lasorella, T. Uo, and A. Iavarone (2001). Id proteins at the cross-road of development and cancer. Oncogene 20:8326-8333.
    • (2001) Oncogene , vol.20 , pp. 8326-8333
    • Lasorella, A.1    Uo, T.2    Iavarone, A.3
  • 104
    • 0031024647 scopus 로고    scopus 로고
    • Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors
    • E. Hara, M. Hall, and G. Peters (1997). Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors. EMBO J. 16:332-342.
    • (1997) EMBO J. , vol.16 , pp. 332-342
    • Hara, E.1    Hall, M.2    Peters, G.3
  • 105
    • 0030712867 scopus 로고    scopus 로고
    • Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation
    • R. W. Deed, E. Hara, G. T. Atherton, G. Peters, and J. D. Norton (1997). Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation. Mol. Cell Biol. 17:6815-6821.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6815-6821
    • Deed, R.W.1    Hara, E.2    Atherton, G.T.3    Peters, G.4    Norton, J.D.5
  • 106
    • 0035914345 scopus 로고    scopus 로고
    • Id-1, ITF-2, and Id-2 comprise a network of helix loop helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis
    • S. Parrinello, C. Q. Lin, K. Murata, Y. Itahana, J. Singh, A. Krtolica, J. Campisi, and P. Y. Desprez (2001). Id-1, ITF-2, and Id-2 comprise a network of helix loop helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis. J. Biol. Chem. 276:39213-39219.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39213-39219
    • Parrinello, S.1    Lin, C.Q.2    Murata, K.3    Itahana, Y.4    Singh, J.5    Krtolica, A.6    Campisi, J.7    Desprez, P.Y.8
  • 107
    • 0032892185 scopus 로고    scopus 로고
    • Regulation of mammary epithelial cell phenotypes by the helix-loop-helix protein, Id-1
    • C. Q. Lin, S. Parrinello, J. Campisi, and P. Y. Desprez (1999). Regulation of mammary epithelial cell phenotypes by the helix-loop-helix protein, Id-1. Endocr. Relat. Cancer 6:49-50.
    • (1999) Endocr. Relat. Cancer , vol.6 , pp. 49-50
    • Lin, C.Q.1    Parrinello, S.2    Campisi, J.3    Desprez, P.Y.4
  • 108
    • 0029024931 scopus 로고
    • Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1
    • P. Y. Desprez, E. Hara, M. J. Bissell, J. Campisi (1995). Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1. Mol. Cell Biol. 15:3398-3404.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3398-3404
    • Desprez, P.Y.1    Hara, E.2    Bissell, M.J.3    Campisi, J.4
  • 109
    • 0034332415 scopus 로고    scopus 로고
    • Lactation defect in mice lacking the helix-loop-helix inhibitor Id2
    • S. Mori, S. I. Nishikawa, and Y. Yokota (2000). Lactation defect in mice lacking the helix-loop-helix inhibitor Id2. EMBO J. 19:5772-5781.
    • (2000) EMBO J. , vol.19 , pp. 5772-5781
    • Mori, S.1    Nishikawa, S.I.2    Yokota, Y.3
  • 110
    • 0031923282 scopus 로고    scopus 로고
    • Coupling of cell growth control and apoptosis functions of Id proteins
    • J. D. Norton, and G. T. Atherton (1998). Coupling of cell growth control and apoptosis functions of Id proteins. Mol. Cell Biol. 18:2371-2381.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2371-2381
    • Norton, J.D.1    Atherton, G.T.2
  • 112
  • 114
    • 4344712469 scopus 로고    scopus 로고
    • Id1 is a critical target of c-myc in breast cancer cells
    • 42nd American Society for Cell Biology Annual Meeting, Abstract 2438. 2002
    • A. Swarbrick, J. Hunter, S. Lee, M. Sergio, R. L. Sutherlan, and E. A. Musgrove (2002). Id1 is a critical target of c-myc in breast cancer cells. In Molecular Biology of the Cell, 42nd American Society for Cell Biology Annual Meeting, Abstract 2438. 2002.
    • (2002) Molecular Biology of the Cell
    • Swarbrick, A.1    Hunter, J.2    Lee, S.3    Sergio, M.4    Sutherlan, R.L.5    Musgrove, E.A.6
  • 117
    • 1642523489 scopus 로고    scopus 로고
    • Helix-loop-helix proteins in mammary gland development and breast cancer
    • P. Y. Desprez, T. Sumida, and J. P. Coppe (2003). helix-loop-helix proteins in mammary gland development and breast cancer. J. Mammary Gland Biol. Neoplasia 8:225-239.
    • (2003) J. Mammary Gland Biol. Neoplasia , vol.8 , pp. 225-239
    • Desprez, P.Y.1    Sumida, T.2    Coppe, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.