Homeobox genes: A link between development, cell cycle, and cancer?

Cell Biology International

Volumn 22, Issue 6, 1998, Pages 397-400

  Ford, Heide L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN;

CANCER; CANCER GENETICS; CELL CYCLE; GENE FUNCTION; GENE OVEREXPRESSION; HOMEOBOX; HUMAN; HUMAN CELL; SHORT SURVEY;

EID: 0032419148     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1998.0329     Document Type: Review

References (28)

1. ANBAZHAGAN R, RAMAN V, 1997. Homeobox genes: Molecular link between congenital anomalies and cancer. Eur J Cancer 33: 635-637.
2. BRIDGES CB, MORGAN TH, 1923. The third chromosome group of mutant characters of Drosophila melanogaster. Carnegie Inst Wash 327: 93.
3. CHARIOT A, CASTRONOVO V, 1996. Detection of HOXA1 expression in human breast cancer. Biochem Biophys Res Commun 222: 292-297.
4. CASTRONOVO V, KUSAKE M, CHARIOT A, GIELEN J, SOBEL M, 1994. Homeobox genes: Potential candidates for the transcriptional control of the transformed and invasive phenotype. Biochem Pharmacol 47: 137-143.
5. CHEYETTE BNR, GREEN PJ, MARTIN K, GARREN H, HARTENSTEIN V, ZIPURSKY SL, 1994. The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron 12: 977-996.
6. CILLO C, 1994. HOX genes in human cancers. Invasion Metastasis 14: 38-49.
7. DAVEY S, HAN CS, RAMER SA, KLASSEN JC, JACOBSON A, EISENBERGER A, HOPKINS KM, LIEBERMAN HB, FREYER GA, 1998. Fission yeast RAD12(+) regulates cell cycle checkpoint control and is homologous to the Blooms-syndrome disease gene. Mol Cell Biol 18: 2721-2728.
8. FORD HL, KABINGU EK, BUMP EA, MUTTER GL, PARDEE AB, 1998. Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis. Proc Natl Acad Sci USA 95: 12,608-12,613.
9. GAO AC, ISAACS JT, 1996. Expression of the homeobox gene-GBX2 in human prostate cancer cells. Prostate 29: 395-398.
10. HATANO M, ROBERTS CW, MINDEN M, CRIST WM, KORSEMEYER SJ, 1991. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 253: 79-82.
11. JACKS T, WEINBERG RA, 1998. The expanding role of cell cycle regulators. Science 280: 1035-1037.
12. KAWABE T, MUSLIN AJ, KORSMEYER S, 1997. HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint. Nature 385: 454-458.
13. KUPFER GM, D'ANDREA AD, 1996. The effect of the Fanconi Anemia polypeptide, FAC, upon p53 induction and G2 checkpoint regulation. Blood 88: 1019-1025.
14. LAWRENCE HJ, SAUVAGEAU G, HUMPHRIES RK, LARGMAN C, 1996. The Role of HOX Homeobox Genes in Normal and Leukemic Hematapoiesis. Stem Cells 14: 281-291.
15. LIU H, BIRD C, 1998. Characterization of the enhancer-like okadaic acid response element region of the cyclin-dependent kinase 1 (p34cdc2) promoter. Biochem Biophys Res Commun 246: 696-702.
16. MAGLI MC, BARBA P, CELETTI A, DEVITA G, CILLO C, BONCINELLI E, 1991. Coordinate regulation of HOX genes in human hematopoietic cells. Proc Natl Acad Sci USA 88: 6348-6353.
17. MALLO GV, RECHRECHE H, FRIGERIO J-M, ROCHA D, ZWEIBAUM A, LACASA M, JORDAN BR, DUSETTI NJ, DAGORN J-C, IOVANNA JL, 1997. Molecular cloning, sequencing and expression of the MRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int J Cancer 74: 35-44.
18. MCGINNIS W, KRUMLAUFF R, 1992. Homeobox genes and axial patterning. Cell 68: 283-302.
19. NOURSE J, MELLETIN JD, GALILI N, WILKINSON J, STANBRIDGE E, SMITH SD, CLEARY ML, 1990. Chromosomal translocation t (1:19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 60: 535-546.
20. OLIVER G, WEHR R, JENKINS NA, COPELAND BG, CHEYETTE BNR, HARTENSTEIN V, ZIPURSKY SL, GRUSS P, 1995. Homeobox genes and connective tissue patterning. Development 121: 693-705.
21. PAULES RS, LEVEDAKOU EN, WILSON SJ, INNES CL, RHODES N, TLSTY TD, GALLOWAY DA, DONEHOWER LA, TAINSKY MA, KAUFMANN WK, 1995. Defective G(2) checkpoint function in cells from individuals with familial cancer syndromes. Cancer Res 55: 1763-1773.
22. SCOTT D, SPREADBOROUGH AR, ROBERTS SA, 1994. Radiation-induced G(2) delay and spontaneous chromosome aberrations in ataxia-telangiectasia homozygotes and heterozygotes. Int J Radiation Biol 66: S157-S163.
23. SMITH RC, BRANELLEC D, GORSKI DH, GUO K, PERLMAN H, DEDIEU J-F, PASTORE C, MAHFOUDI A, DENEFLE P, ISNER JM, WALSH K, 1997. p21CIP1-Mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes Dev 11: 1674-1689.
24. STEIN S, FRITSCH R, LEMAIRE L, KESSEL M, 1996. Checklist: Vertebrate homeobox genes. Mech Develop 55: 91-108.
25. STERN S, HERR W, 1991. The herpes simplex virus transactivator VP16 recognizes the Oct-1 homeodomain: evidence for a homeodomain recognition subdomain. Genes Dev 5: 2555-2563.
26. STUART ET, GRUSS P, 1995. PAX genes: what's new in developmental biology and cancer? Human Mol Genet 4: 1717-1720.
27. STUKENBERG PT, LUSTIG KD, MCGARRY TJ, KING RW, KUANG J, KIRSCHNER MW, 1997. Systematic identification of mitotic phosphoproteins. Curr Bioll: 338-348.
28. ZHANG N, GONG Z-Z, MINDEN M, LU M, 1993. The HOX-11 (TCL-3) homeobox proto-oncogene encodes a nuclear protein that undergoes cell cycle-dependent regulation. Oncogene 8: 3265-3270.