-
1
-
-
0021997185
-
Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
-
Sakaguchi, S., K. Fukuma, K. Kuribayashi & T. Masuda: Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161, 72-87 (1985)
-
(1985)
J. Exp. Med.
, vol.161
, pp. 72-87
-
-
Sakaguchi, S.1
Fukuma, K.2
Kuribayashi, K.3
Masuda, T.4
-
2
-
-
0028179230
-
+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
-
+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179, 589-600 (1994)
-
(1994)
J. Exp. Med.
, vol.179
, pp. 589-600
-
-
Powrie, F.1
Correa-Oliviera, R.2
Mauze, S.3
Coffman, R.L.4
-
7
-
-
0026761052
-
Tolerance mechanism in experimental pvarian and gastric autoimmune disease
-
Smith, H. Y. Lou, P. Lacy & K.S. Tung: Tolerance mechanism in experimental pvarian and gastric autoimmune disease. J. Immunol. 149, 2212-2218 (1992)
-
(1992)
J. Immunol.
, vol.149
, pp. 2212-2218
-
-
Smith, H.1
Lou, Y.2
Lacy, P.3
Tung, K.S.4
-
8
-
-
0025949001
-
Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy
-
Smith, H., Y. Sakamoto, K Kasai, and K.S. Tung: Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. J. Immunol. 147, 2928-2933 (1991)
-
(1991)
J. Immunol.
, vol.147
, pp. 2928-2933
-
-
Smith, H.1
Sakamoto, Y.2
Kasai, K.3
Tung, K.S.4
-
9
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, & M. Toda: Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164 (1995)
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
10
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano, M., M. Toda, N. Sakaguchi & S. Sakaguchi: Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184, 387-396 (1996)
-
(1996)
J. Exp. Med.
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
11
-
-
0031939403
-
+T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
-
+T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160, 1212-1218 (1998)
-
(1998)
J. Immunol.
, vol.160
, pp. 1212-1218
-
-
Suri-Payer, E.1
Amar, A.Z.2
Thornton, A.M.3
Shevach, E.M.4
-
12
-
-
0034679567
-
+ regulatory cells that control intestinal inflammation
-
+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192, 295-302 (2000)
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
13
-
-
0031647622
-
+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10, 1969-1980 (1998)
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
15
-
-
0031821875
-
+Immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+Immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188, 287-296 (1998)
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
19
-
-
0030056468
-
Models of T cell anergy: Is there a common molecular mechanism?
-
R.H. Schwartz: Models of T cell anergy: Is there a common molecular mechanism? J. Exp. Med. 184, 1-8 (1996)
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1-8
-
-
Schwartz, R.H.1
-
23
-
-
0033985780
-
+immunoregulatory T cells is antigen nonspecific
-
+immunoregulatory T cells is antigen nonspecific. J. Immunol. 164, 183-190 (2000)
-
(2000)
J. Immunol.
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
24
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno, B.M. & M. Collins: The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20, 29-53 (2002)
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
25
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P., J.M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K.P. Lee, C.B. Thompson, H. Griesser & T.W. Mak: Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science. 270, 985-988 (1995)
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
26
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal -multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E.A., F. Borriello, A.N. Schweitzer, W.P. Lynch, J.A. Bluestone & A.H. Sharpe: Loss of CTLA-4 leads to massive lymphoproliferation and fatal -multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity. 3, 541-547 (1995)
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
27
-
-
0035102196
-
CTLA-4 regulates induction of anergy in vivo
-
Greenwald, R.J., V.A. Boussiotis, R.B. Lorsbach, A.K. Abbas & A.H. Sharpe: CTLA-4 regulates induction of anergy in vivo. Immunity. 14, 145-155 (2001)
-
(2001)
Immunity
, vol.14
, pp. 145-155
-
-
Greenwald, R.J.1
Boussiotis, V.A.2
Lorsbach, R.B.3
Abbas, A.K.4
Sharpe, A.H.5
-
28
-
-
0034679560
-
+ regulatory T cells constitutively expressing cytotoxic T lymphcyte-associated antigen 4
-
+ regulatory T cells constitutively expressing cytotoxic T lymphcyte-associated antigen 4. J. Exp. Med. 192, 303-309 (2000)
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-309
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.7
Sakaguchi, S.8
-
29
-
-
0035801335
-
+regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
+regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 194, 629-644 (2001)
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
30
-
-
0036467522
-
+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 168, 1080-1086 (2002)
-
(2002)
J. Immunol.
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
33
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K.W., R. de Waal Malefyt, R.L. Coffman, & A. O'Garra: Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765 (2001)
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
De Waal Malefyt, R.2
Coffman, R.L.3
O'Garra, A.4
-
34
-
-
0033523607
-
An essential role for interleukin-10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., S. Mauze, M.W. Leach, R.L. Coffman & F. Powrie: An essential role for interleukin-10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190, 995-1003 (1999)
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1003
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
36
-
-
0037099613
-
+regulatory T cells can mediate suppressor function in the absence of transforming growth factor betal production and responsiveness
-
+regulatory T cells can mediate suppressor function in the absence of transforming growth factor betal production and responsiveness. J. Exp. Med. 196, 237-245 (2002)
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-245
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
37
-
-
0031944290
-
Regulation of immune responses by TGF-beta
-
Letterio, J.J. & A.B. Roberts: Regulation of immune responses by TGF-beta. Annu. Rev. Immunol. 16, 137-61, (1998)
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 137-161
-
-
Letterio, J.J.1
Roberts, A.B.2
-
39
-
-
0035879091
-
Regulation of TGF-beta response during T cell activation is modulated by IL-10
-
Cottrez, F. & H. Groux: Regulation of TGF-beta response during T cell activation is modulated by IL-10. J. Immunol. 167, 773-778 (2001)
-
(2001)
J. Immunol.
, vol.167
, pp. 773-778
-
-
Cottrez, F.1
Groux, H.2
-
40
-
-
0028972556
-
TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor-bearing mice
-
Maeda, H., H. Kuwahara, Y. Ichimura, M. Ohtsuki, S. Kurakata & A. Shiraishi: TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor-bearing mice. J. Immunol. 155, 4926-4932 (1995)
-
(1995)
J. Immunol.
, vol.155
, pp. 4926-4932
-
-
Maeda, H.1
Kuwahara, H.2
Ichimura, Y.3
Ohtsuki, M.4
Kurakata, S.5
Shiraishi, A.6
-
41
-
-
0034077559
-
+regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
+regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur. J. Immunol. 30, 1538-1543 (2000)
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
42
-
-
0035525739
-
Human CD4(+)CD25(+) cells: A naturally occurring population of regulatory T cells
-
Ng, W.F., P.J. Duggan, F. Ponchel, G. Matarese, G. Lombardi, A.D. Edwards, J.D. Isaacs & R.I. Lechler: Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells. Blood 98, 2736-2744 (2001)
-
(2001)
Blood
, vol.98
, pp. 2736-2744
-
-
Ng, W.F.1
Duggan, P.J.2
Ponchel, F.3
Matarese, G.4
Lombardi, G.5
Edwards, A.D.6
Isaacs, J.D.7
Lechler, R.I.8
-
43
-
-
7144259082
-
Regulatory CD4 T cells: Expression of IL-2Ralpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik, M., M.L. de Moraes, C. Pontoux, F. Vasseur & C. Penit: Regulatory CD4 T cells: expression of IL-2Ralpha chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10, 371-378 (1998)
-
(1998)
Int. Immunol.
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
De Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
44
-
-
0033136302
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317-5326 (1999)
-
(1999)
J. Immunol.
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
Kuniyasu, Y.4
Shimizu, J.5
Otsuka, F.6
Sakaguchi, S.7
-
46
-
-
0035320679
-
+regulatory T cells induced by an agonist self-peptide
-
+regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2, 301-306 (2001)
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
47
-
-
0037218548
-
+immunoregulatory CD4 T cells mediate acquired central transplantation tolerance
-
+immunoregulatory CD4 T cells mediate acquired central transplantation tolerance. J. Immunol. 170, 279-286 (2003)
-
(2003)
J. Immunol.
, vol.170
, pp. 279-286
-
-
Trani, J.1
Moore, D.J.2
Jarrett, B.P.3
Markmann, J.W.4
Lee, M.K.5
Singer, A.6
Lian, M.M.7
Tran, B.8
Caton, A.J.9
Markmann, J.F.10
-
48
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S. T. Nomura and S. Sakaguchi: Control of regulatory T cell development by the transcription factor Foxp3. Science. 299, 1057-1061 (2003)
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
49
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., M.A. Gavin and A.Y. Rudensky: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4, 330-336 (2003)
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
50
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., T. Cox, S.A. Yasayko and F. Ramsdell: An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4, 337-342, (2003)
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
51
-
-
0033571454
-
CD4+CD45RB low-density cells from untreated mice prevent acute allograft rejection
-
Davies, J.D., E. O'Connor, D. Hall, T. Krahl, J. Trotter & N. Sarvetnick: CD4+CD45RB low-density cells from untreated mice prevent acute allograft rejection. J. Immunol. 163, 5353-5357 (1999)
-
(1999)
J. Immunol.
, vol.163
, pp. 5353-5357
-
-
Davies, J.D.1
O'Connor, E.2
Hall, D.3
Krahl, T.4
Trotter, J.5
Sarvetnick, N.6
-
53
-
-
0035869432
-
IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
-
Hara, M., C.I. Kingsley, M. Niimi, S. Read, S.E. Turvey, A.R. Bushell, P.J. Morris, F. Powrie & K.J. Wood: IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J. Immunol. 166, 3789-3796 (2001)
-
(2001)
J. Immunol.
, vol.166
, pp. 3789-3796
-
-
Hara, M.1
Kingsley, C.I.2
Niimi, M.3
Read, S.4
Turvey, S.E.5
Bushell, A.R.6
Morris, P.J.7
Powrie, F.8
Wood, K.J.9
-
55
-
-
0033136945
-
Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effector function is linked to proliferative capacity
-
Gudmundsdottir, H., A.D. Wells & L.A.Turka: Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity. J. Immunol. 162, 5212-5223 (1999)
-
(1999)
J. Immunol.
, vol.162
, pp. 5212-5223
-
-
Gudmundsdottir, H.1
Wells, A.D.2
Turka, L.A.3
-
56
-
-
0037124359
-
Identification of regulatory T cells in tolerated allografts
-
Graca, L., S.P. Cobbold & H. Waldmann: Identification of regulatory T cells in tolerated allografts. J Exp. Med. 195, 1641-1646 (2002)
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1641-1646
-
-
Graca, L.1
Cobbold, S.P.2
Waldmann, H.3
-
57
-
-
0036467347
-
Regulatory T cells overexpress a subset of Th2 gene transcripts
-
Zelenika, D., E. Adams, S. Humm, L. Graca, S. Thompson, S.P. Cobbold and H. Waldmann: Regulatory T cells overexpress a subset of Th2 gene transcripts. J. Immunol. 168, 1069-1079 (2002)
-
(2002)
J. Immunol.
, vol.168
, pp. 1069-1079
-
-
Zelenika, D.1
Adams, E.2
Humm, S.3
Graca, L.4
Thompson, S.5
Cobbold, S.P.6
Waldmann, H.7
-
58
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., A. Sarukhan, L. Klein & H. von Boehmer: Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3, 756-763 (2002)
-
(2002)
Nat. Immunol.
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
Von Boehmer, H.4
-
59
-
-
0025602264
-
The induction of skin graft tolerance in MHC mismatched or primed recipients: Primed T cells can be tolerised in the periphery by CD4 and CD8 antibodies
-
Cobbold, S.P., G. Martin & H. Waldmann. The induction of skin graft tolerance in MHC mismatched or primed recipients: primed T cells can be tolerised in the periphery by CD4 and CD8 antibodies. Eur. J. Immunol. 20, 2747-2755 (1990)
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 2747-2755
-
-
Cobbold, S.P.1
Martin, G.2
Waldmann, H.3
-
60
-
-
0026577832
-
Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, using monoclonal antibodies to CD4 and CD8
-
Chen, Z., S.P. Cobbold, S. Metcalfe & H. Waldmann: Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, using monoclonal antibodies to CD4 and CD8. Eur. J. Immunol. 22, 805-810 (1992)
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 805-810
-
-
Chen, Z.1
Cobbold, S.P.2
Metcalfe, S.3
Waldmann, H.4
-
61
-
-
0030461536
-
Amplification of natural regulatory immune mechanisms for transplantation tolerance
-
Chen, Z.K., S.P. Cobbold, H. Waldmann & S. Metcalfe: Amplification of natural regulatory immune mechanisms for transplantation tolerance. Transplantation 62, 1200-1206 (1996)
-
(1996)
Transplantation
, vol.62
, pp. 1200-1206
-
-
Chen, Z.K.1
Cobbold, S.P.2
Waldmann, H.3
Metcalfe, S.4
-
62
-
-
0025674112
-
Induction of tolerance in peripheral T cells with monoclonal antibodies
-
Qin, S., M. Wise, S.P. Cobbold, L.Y.W. Leong, Y.M. Kong, J.R. Parnes & H. Waldmann: Induction of tolerance in peripheral T cells with monoclonal antibodies. Eur. J. Immunol. 20, 2737-2745 (1990)
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 2737-2745
-
-
Qin, S.1
Wise, M.2
Cobbold, S.P.3
Leong, L.Y.W.4
Kong, Y.M.5
Parnes, J.R.6
Waldmann, H.7
-
63
-
-
0016588323
-
A disquisition on suppressor T cells
-
R.K. Gershon: A disquisition on suppressor T cells. Transplant Rev. 26, 170-185 (1975)
-
(1975)
Transplant Rev.
, vol.26
, pp. 170-185
-
-
Gershon, R.K.1
-
64
-
-
0029918208
-
T cell suppression in transplantation tolerance through linked recognition
-
Davies, J.D., L.Y.W. Leong, A. Mellor, S.P. Cobbold & H. Waldmann: T cell suppression in transplantation tolerance through linked recognition. J. Immunol. 156, 3602-3607 (1996)
-
(1996)
J. Immunol.
, vol.156
, pp. 3602-3607
-
-
Davies, J.D.1
Leong, L.Y.W.2
Mellor, A.3
Cobbold, S.P.4
Waldmann, H.5
-
65
-
-
0035025617
-
Chronic Rejection
-
Libby, P. & J.S. Pober: Chronic Rejection. Immunity. 14, 387-397 (2001)
-
(2001)
Immunity
, vol.14
, pp. 387-397
-
-
Libby, P.1
Pober, J.S.2
|