메뉴 건너뛰기




Volumn 15, Issue 5, 2008, Pages 459-466

Inhibition of Polo-like Kinase 1 by Blocking Polo-Box Domain-Dependent Protein-Protein Interactions

Author keywords

CHEMBIO; SIGNALING

Indexed keywords


EID: 43149093993     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2008.03.013     Document Type: Article
Times cited : (218)

References (36)
  • 1
  • 2
    • 0242556820 scopus 로고    scopus 로고
    • The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex
    • K.Y. Cheng E.D. Lowe J. Sinclair E.A. Nigg L.N. Johnson The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex EMBO J. 22 2003 5757 5768
    • (2003) EMBO J. , vol.22 , pp. 5757-5768
    • Cheng, K.Y.1    Lowe, E.D.2    Sinclair, J.3    Nigg, E.A.4    Johnson, L.N.5
  • 3
    • 27144475507 scopus 로고    scopus 로고
    • Investigation of the binding determinants of phosphopeptides targeted to the Src homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor
    • D.R. Coleman Z. Ren P.K. Mandal A.G. Cameron G.A. Dyer S. Muranjan M. Campbell X. Chen J.S. McMurray Investigation of the binding determinants of phosphopeptides targeted to the Src homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor J. Med. Chem. 48 2005 6661 6670
    • (2005) J. Med. Chem. , vol.48 , pp. 6661-6670
    • Coleman, D.R.1    Ren, Z.2    Mandal, P.K.3    Cameron, A.G.4    Dyer, G.A.5    Muranjan, S.6    Campbell, M.7    Chen, X.8    McMurray, J.S.9
  • 4
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: triumphs and trials
    • T.W. Corson C.M. Crews Molecular understanding and modern application of traditional medicines: triumphs and trials Cell 130 2007 769 774
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1    Crews, C.M.2
  • 5
    • 10444280878 scopus 로고    scopus 로고
    • Strategies to overcome resistance to targeted protein kinase inhibitors
    • H. Daub K. Specht A. Ullrich Strategies to overcome resistance to targeted protein kinase inhibitors Nat. Rev. Drug Discov. 3 2004 1001 1010
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 1001-1010
    • Daub, H.1    Specht, K.2    Ullrich, A.3
  • 6
    • 0033638454 scopus 로고    scopus 로고
    • The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms
    • D. Durocher I.A. Taylor D. Sarbassova L.F. Haire S.L. Westcott S.P. Jackson S.J. Smerdon M.B. Yaffe The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms Mol. Cell 6 2000 1169 1182
    • (2000) Mol. Cell , vol.6 , pp. 1169-1182
    • Durocher, D.1    Taylor, I.A.2    Sarbassova, D.3    Haire, L.F.4    Westcott, S.L.5    Jackson, S.P.6    Smerdon, S.J.7    Yaffe, M.B.8
  • 7
    • 0242515843 scopus 로고    scopus 로고
    • Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates
    • A.E. Elia L.C. Cantley M.B. Yaffe Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates Science 299 2003 1228 1231
    • (2003) Science , vol.299 , pp. 1228-1231
    • Elia, A.E.1    Cantley, L.C.2    Yaffe, M.B.3
  • 9
    • 37549065191 scopus 로고    scopus 로고
    • Cell type-dependent effects of Polo-like kinase 1 inhibition compared with targeted polo box interference in cancer cell lines
    • J. Fink K. Sanders A. Rippl S. Finkernagel T.L. Beckers M. Schmidt Cell type-dependent effects of Polo-like kinase 1 inhibition compared with targeted polo box interference in cancer cell lines Mol. Cancer Ther. 6 2007 3189 3197
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3189-3197
    • Fink, J.1    Sanders, K.2    Rippl, A.3    Finkernagel, S.4    Beckers, T.L.5    Schmidt, M.6
  • 13
    • 30044436805 scopus 로고    scopus 로고
    • Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting
    • A. Hanisch A. Wehner E.A. Nigg H.H. Sillje Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting Mol. Biol. Cell 17 2006 448 459
    • (2006) Mol. Biol. Cell , vol.17 , pp. 448-459
    • Hanisch, A.1    Wehner, A.2    Nigg, E.A.3    Sillje, H.H.4
  • 14
    • 33744520878 scopus 로고    scopus 로고
    • Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis
    • N. Jiang X. Wang M. Jhanwar-Uniyal Z. Darzynkiewicz W. Dai Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis J. Biol. Chem. 281 2006 10577 10582
    • (2006) J. Biol. Chem. , vol.281 , pp. 10577-10582
    • Jiang, N.1    Wang, X.2    Jhanwar-Uniyal, M.3    Darzynkiewicz, Z.4    Dai, W.5
  • 16
    • 33746239002 scopus 로고    scopus 로고
    • Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules
    • A. Kiessling B. Sperl A. Hollis D. Eick T. Berg Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules Chem. Biol. 13 2006 745 751
    • (2006) Chem. Biol. , vol.13 , pp. 745-751
    • Kiessling, A.1    Sperl, B.2    Hollis, A.3    Eick, D.4    Berg, T.5
  • 19
    • 0038624074 scopus 로고    scopus 로고
    • Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
    • X. Liu R.L. Erikson Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells Proc. Natl. Acad. Sci. USA 100 2003 5789 5794
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5789-5794
    • Liu, X.1    Erikson, R.L.2
  • 20
    • 12344256951 scopus 로고    scopus 로고
    • Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase
    • Y. Liu K.R. Shreder W. Gai S. Corral D.K. Ferris J.S. Rosenblum Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase Chem. Biol. 12 2005 99 107
    • (2005) Chem. Biol. , vol.12 , pp. 99-107
    • Liu, Y.1    Shreder, K.R.2    Gai, W.3    Corral, S.4    Ferris, D.K.5    Rosenblum, J.S.6
  • 21
    • 17144393305 scopus 로고    scopus 로고
    • Progress in the discovery of polo-like kinase inhibitors
    • C. McInnes M. Mezna P.M. Fischer Progress in the discovery of polo-like kinase inhibitors Curr. Top. Med. Chem. 5 2005 181 197
    • (2005) Curr. Top. Med. Chem. , vol.5 , pp. 181-197
    • McInnes, C.1    Mezna, M.2    Fischer, P.M.3
  • 23
    • 0033773937 scopus 로고    scopus 로고
    • Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer
    • J.C. Owicki Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer J. Biomol. Screen. 5 2000 297 306
    • (2000) J. Biomol. Screen. , vol.5 , pp. 297-306
    • Owicki, J.C.1
  • 24
    • 33750238670 scopus 로고    scopus 로고
    • Probing cell-division phenotype space and Polo-like kinase function using small molecules
    • U. Peters J. Cherian J.H. Kim B.H. Kwok T.M. Kapoor Probing cell-division phenotype space and Polo-like kinase function using small molecules Nat. Chem. Biol. 2 2006 618 626
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 618-626
    • Peters, U.1    Cherian, J.2    Kim, J.H.3    Kwok, B.H.4    Kapoor, T.M.5
  • 27
    • 33646794376 scopus 로고    scopus 로고
    • Cytostatic factor: an activity that puts the cell cycle on hold
    • A. Schmidt N.R. Rauh E.A. Nigg T.U. Mayer Cytostatic factor: an activity that puts the cell cycle on hold J. Cell Sci. 119 2006 1213 1218
    • (2006) J. Cell Sci. , vol.119 , pp. 1213-1218
    • Schmidt, A.1    Rauh, N.R.2    Nigg, E.A.3    Mayer, T.U.4
  • 28
    • 2942579547 scopus 로고    scopus 로고
    • A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3
    • J. Schust T. Berg A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3 Anal. Biochem. 330 2004 114 118
    • (2004) Anal. Biochem. , vol.330 , pp. 114-118
    • Schust, J.1    Berg, T.2
  • 29
    • 33750982120 scopus 로고    scopus 로고
    • Stattic: a small-molecule inhibitor of STAT3 activation and dimerization
    • J. Schust B. Sperl A. Hollis T.U. Mayer T. Berg Stattic: a small-molecule inhibitor of STAT3 activation and dimerization Chem. Biol. 13 2006 1235 1242
    • (2006) Chem. Biol. , vol.13 , pp. 1235-1242
    • Schust, J.1    Sperl, B.2    Hollis, A.3    Mayer, T.U.4    Berg, T.5
  • 30
    • 0037132736 scopus 로고    scopus 로고
    • Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
    • B. Spankuch-Schmitt J. Bereiter-Hahn M. Kaufmann K. Strebhardt Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells J. Natl. Cancer Inst. 94 2002 1863 1877
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 1863-1877
    • Spankuch-Schmitt, B.1    Bereiter-Hahn, J.2    Kaufmann, M.3    Strebhardt, K.4
  • 34
    • 33645316142 scopus 로고    scopus 로고
    • Targeting polo-like kinase 1 for cancer therapy
    • K. Strebhardt A. Ullrich Targeting polo-like kinase 1 for cancer therapy Nat. Rev. Cancer 6 2006 321 330
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 321-330
    • Strebhardt, K.1    Ullrich, A.2
  • 36
    • 0036682358 scopus 로고    scopus 로고
    • Efficient internalization of the polo-box of polo-like kinase 1 fused to an Antennapedia peptide results in inhibition of cancer cell proliferation
    • J. Yuan A. Kramer F. Eckerdt M. Kaufmann K. Strebhardt Efficient internalization of the polo-box of polo-like kinase 1 fused to an Antennapedia peptide results in inhibition of cancer cell proliferation Cancer Res. 62 2002 4186 4190
    • (2002) Cancer Res. , vol.62 , pp. 4186-4190
    • Yuan, J.1    Kramer, A.2    Eckerdt, F.3    Kaufmann, M.4    Strebhardt, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.