The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

EMBO Journal

Volumn 22, Issue 21, 2003, Pages 5757-5768

  Cheng, Kin Yip ^a   Lowe, Edward D ^a   Sinclair, John ^a   Nigg, Erich A ^b   Johnson, Louise N ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c NONE

Author keywords

Cell cycle control; Phospho peptide recognition; Plk1; Polo box domain; Protein structure

Indexed keywords

HISTIDINE; LEUCINE; LYSINE; PHOSPHOPEPTIDE; POLO LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CENTROMERE; CENTROSOME; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; MITOSIS; MUTATION; NONHUMAN; POLO BOX DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SPINDLE CELL;

AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN KINASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0242556820     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg558     Document Type: Article

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