Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis

Journal of Biological Chemistry

Volumn 281, Issue 15, 2006, Pages 10577-10582

  Jiang, Ning ^a   Wang, Xiaoxing ^a   Jhanwar Uniyal, Meena ^a   Darzynkiewicz, Zbigniew ^a   Dai, Wei ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; DRUG PRODUCTS; GENES;

ANTICANCER DRUGS; APOPTOSIS; CYTOKINESIS DEFECTS; THERAPEUTIC TARGET;

ENZYMES;

MUTANT PROTEIN; POLO LIKE KINASE 1; POLO LIKE KINASE 3; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; DNA; GREEN FLUORESCENT PROTEIN; ONCOPROTEIN; PLK3 PROTEIN, HUMAN; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; CYTOKINESIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPINDLE POLE BODY; BIOLOGICAL MODEL; CHEMISTRY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HELA CELL; IMMUNOBLOTTING; METABOLISM; MITOSIS; NEOPLASM; NUCLEAR LOCALIZATION SIGNAL; PHYSIOLOGY; PLASMID; PROTEIN TERTIARY STRUCTURE; TIME; TUMOR CELL LINE; ULTRASTRUCTURE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CENTROSOME; CYTOKINESIS; DNA; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MITOSIS; MODELS, GENETIC; MUTATION; NEOPLASMS; NUCLEAR LOCALIZATION SIGNALS; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TIME FACTORS; TRANSFECTION;

EID: 33744520878     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513156200     Document Type: Article

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