-
1
-
-
0023223148
-
The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases
-
Appella, E. The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases. J Biol Chem 1987, 262(10): 4437-40.
-
(1987)
J Biol Chem
, vol.262
, Issue.10
, pp. 4437-4440
-
-
Appella, E.1
-
2
-
-
0024195895
-
Proteolytic mechanisms operating at the surface of invasive cells
-
Pollanen, J., Stephens, R., Salonen, E.M. and Vaheri, A. Proteolytic mechanisms operating at the surface of invasive cells. Adv Exp Med Biol 1988, 233: 187-99.
-
(1988)
Adv Exp Med Biol
, vol.233
, pp. 187-199
-
-
Pollanen, J.1
Stephens, R.2
Salonen, E.M.3
Vaheri, A.4
-
3
-
-
0025234559
-
Prourokinase activation on the surface of human rhabdomyosarcoma cells: Localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class-2 plasminogen activator inhibitor
-
Pollanen, J., Vaheri, A., Tapiovaara, H. et al. Prourokinase activation on the surface of human rhabdomyosarcoma cells: Localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class-2 plasminogen activator inhibitor. Proc Natl Acad Sci U S A 1990, 87(6): 2230-4.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, Issue.6
, pp. 2230-2234
-
-
Pollanen, J.1
Vaheri, A.2
Tapiovaara, H.3
-
4
-
-
0021984227
-
A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase
-
Vassalli, J.D., Baccino, D. and Belin, D. A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase. J Cell Biol 1985, 100(1): 86-92.
-
(1985)
J Cell Biol
, vol.100
, Issue.1
, pp. 86-92
-
-
Vassalli, J.D.1
Baccino, D.2
Belin, D.3
-
5
-
-
0025052018
-
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis
-
Roldan, A.L., Cubellis, M.V., Masucci, M.T. et al. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J 1990, 9(2): 467-74.
-
(1990)
EMBO J
, vol.9
, Issue.2
, pp. 467-474
-
-
Roldan, A.L.1
Cubellis, M.V.2
Masucci, M.T.3
-
6
-
-
0029841102
-
Domain interplay in the urokinase receptor-requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains
-
Behrendt, N., Roenne, E. and Danø, K. Domain interplay in the urokinase receptor-requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains. J Biol Chem 1996, 271(37): 22885-94.
-
(1996)
J Biol Chem
, vol.271
, Issue.37
, pp. 22885-22894
-
-
Behrendt, N.1
Roenne, E.2
Danø, K.3
-
7
-
-
0032564309
-
Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site
-
Ploug, M. Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site. Biochemistry 1998, 37(47): 16494-505.
-
(1998)
Biochemistry
, vol.37
, Issue.47
, pp. 16494-16505
-
-
Ploug, M.1
-
8
-
-
0028334672
-
Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy
-
Høyer-Hansen, G., Behrendt, N., Ploug, M., Danø, K., Waltz, D.A. and Chapman. H.A. Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy. J Biol Chem 1994, 269(20): 14746-50.
-
(1994)
J Biol Chem
, vol.269
, Issue.20
, pp. 14746-14750
-
-
Høyer-Hansen, G.1
Behrendt, N.2
Ploug, M.3
Danø, K.4
Waltz, D.A.5
Chapman, H.A.6
-
9
-
-
0029873910
-
The urokinase receptor is a major vitronectin-binding protein on endothelial cells
-
Kanse, S.M., Kost, C., Wilhelm, O.G., Andreasen, P.A. and Preissner, K.T. The urokinase receptor is a major vitronectin-binding protein on endothelial cells. Exp Cell Res 1996, 224(2): 344-53.
-
(1996)
Exp Cell Res
, vol.224
, Issue.2
, pp. 344-353
-
-
Kanse, S.M.1
Kost, C.2
Wilhelm, O.G.3
Andreasen, P.A.4
Preissner, K.T.5
-
10
-
-
0018893682
-
On the regulation of fibrinolysis
-
Collen, D. On the regulation of fibrinolysis. Thromb Haemost 1980, 43: 77-89.
-
(1980)
Thromb Haemost
, vol.43
, pp. 77-89
-
-
Collen, D.1
-
11
-
-
0027762119
-
Evidence for the regulation of urokinase and tissue type plasminogen activators by the serpin, protein C inhibitor, in semen and blood plasma
-
Espana, F., Estelles, A., Fernandez, P.J., Gilabret, J., Sanchez-Cheuz, J. and Griffin, J.H. Evidence for the regulation of urokinase and tissue type plasminogen activators by the serpin, protein C inhibitor, in semen and blood plasma. Thromb Haemost 1993, 70(6): 989-94.
-
(1993)
Thromb Haemost
, vol.70
, Issue.6
, pp. 989-994
-
-
Espana, F.1
Estelles, A.2
Fernandez, P.J.3
Gilabret, J.4
Sanchez-Cheuz, J.5
Griffin, J.H.6
-
12
-
-
0029087906
-
The versatility of adhesion receptor ligands in haemostasis: Morphoregulatory functions of vitronectin
-
Hess, S., Kanse, S.M., Kost, C. and Preissner, K.T. The versatility of adhesion receptor ligands in haemostasis: Morphoregulatory functions of vitronectin. Thromb Haemost 1995, 74(1): 258-65.
-
(1995)
Thromb Haemost
, vol.74
, Issue.1
, pp. 258-265
-
-
Hess, S.1
Kanse, S.M.2
Kost, C.3
Preissner, K.T.4
-
13
-
-
0023130521
-
Plasminogen activator inhibitors
-
Sprengers, E.D. and Kluft, C. Plasminogen activator inhibitors. Blood 1987, 69(2): 381-7.
-
(1987)
Blood
, vol.69
, Issue.2
, pp. 381-387
-
-
Sprengers, E.D.1
Kluft, C.2
-
14
-
-
0023685082
-
Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin)
-
Declerck, P.J., De Mol, M., Alessi, M.C. et al. Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin). J Biol Chem 1988, 263(30): 15454-61.
-
(1988)
J Biol Chem
, vol.263
, Issue.30
, pp. 15454-15461
-
-
Declerck, P.J.1
De Mol, M.2
Alessi, M.C.3
-
15
-
-
0025273735
-
Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
-
Cubellis, M.V., Wun, T.C. and Blasi, F. Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 1990, 9(4): 1079-85.
-
(1990)
EMBO J
, vol.9
, Issue.4
, pp. 1079-1085
-
-
Cubellis, M.V.1
Wun, T.C.2
Blasi, F.3
-
16
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
Andreasen, P.A., Kjoller, L., Christensen, L. and Duffy, M.J. The urokinase-type plasminogen activator system in cancer metastasis: A review. Int J Cancer 1997, 72(1): 1-22.
-
(1997)
Int J Cancer
, vol.72
, Issue.1
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
17
-
-
0036906177
-
uPAR: A versatile signalling orchestrator
-
Blasi, F. and Carmeliet, P. uPAR: A versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002, 3(12): 932-43.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.12
, pp. 932-943
-
-
Blasi, F.1
Carmeliet, P.2
-
18
-
-
0038364216
-
The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
-
Sidenius, N. and Blasi, F. The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy. Cancer Metastasis Rev 2003, 22(2-3): 205-22.
-
(2003)
Cancer Metastasis Rev
, vol.22
, Issue.2-3
, pp. 205-222
-
-
Sidenius, N.1
Blasi, F.2
-
19
-
-
0029764639
-
Regulation of integrin function by the urokinase receptor
-
Wei, Y. et al. Regulation of integrin function by the urokinase receptor. Science 1996, 273(5281): 1551-5.
-
(1996)
Science
, vol.273
, Issue.5281
, pp. 1551-1555
-
-
Wei, Y.1
-
20
-
-
0029847191
-
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration
-
Yebra, M. et al. Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration. J Biol Chem 1996, 271(46): 29393-9.
-
(1996)
J Biol Chem
, vol.271
, Issue.46
, pp. 29393-29399
-
-
Yebra, M.1
-
21
-
-
0035848682
-
Urokinase/urokinase receptor and vitronectin/avb3 integrin induce Chemotaxis and cytoskeleton reorganization through different signaling pathways
-
Degryse, B., Orlando, S., Resnati, M., Rabbani, S.A. and Blasi, F. Urokinase/urokinase receptor and vitronectin/avb3 integrin induce Chemotaxis and cytoskeleton reorganization through different signaling pathways. Oncogene 2001, 20(16): 2032-43.
-
(2001)
Oncogene
, vol.20
, Issue.16
, pp. 2032-2043
-
-
Degryse, B.1
Orlando, S.2
Resnati, M.3
Rabbani, S.A.4
Blasi, F.5
-
22
-
-
0032555894
-
Urokinase receptor (CD87) regulates leukocyte recruitment via beta2 integrins in vivo
-
May, A. E. et al. Urokinase receptor (CD87) regulates leukocyte recruitment via beta2 integrins in vivo. J Exp Med 1998, 188(6): 1029-37.
-
(1998)
J Exp Med
, vol.188
, Issue.6
, pp. 1029-1037
-
-
May, A.E.1
-
23
-
-
0034037536
-
Nonproteolytic role for the urokinase receptor in cellular migration in vivo
-
Waltz, D.A. et al. Nonproteolytic role for the urokinase receptor in cellular migration in vivo. Am J Respir Cell Mol Biol 2000, 22(3): 316-22.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, Issue.3
, pp. 316-322
-
-
Waltz, D.A.1
-
24
-
-
0033551899
-
Integrin signaling
-
Giancotti, F.G. and Ruoslahti, E. Integrin signaling. Science 1999, 285(5430): 1028-32.
-
(1999)
Science
, vol.285
, Issue.5430
, pp. 1028-1032
-
-
Giancotti, F.G.1
Ruoslahti, E.2
-
25
-
-
0029923744
-
Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect
-
Resnati, M. et al. Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect. EMBO J 1996, 15(7): 1572-82.
-
(1996)
EMBO J
, vol.15
, Issue.7
, pp. 1572-1582
-
-
Resnati, M.1
-
26
-
-
0031463337
-
The urokinase-sensitive region of the urokinase receptor is responsible for its potent chemotactic activity
-
Fazioli, F. et al. The urokinase-sensitive region of the urokinase receptor is responsible for its potent chemotactic activity. EMBO J 1997, 16(24): 7279-86.
-
(1997)
EMBO J
, vol.16
, Issue.24
, pp. 7279-7286
-
-
Fazioli, F.1
-
27
-
-
0033566354
-
Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis, and cytoskeleton reorganization in rat smooth muscle cells via the urokinase receptor
-
Degryse, B. et al. Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis, and cytoskeleton reorganization in rat smooth muscle cells via the urokinase receptor. Blood 1999, 94(2): 649-62.
-
(1999)
Blood
, vol.94
, Issue.2
, pp. 649-662
-
-
Degryse, B.1
-
28
-
-
0034705424
-
Urokinase-type plasminogen activator stimulates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells
-
Nguyen, D.H. et al. Urokinase-type plasminogen activator stimulates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells. J Biol Chem 2000, 275(25): 19382-8.
-
(2000)
J Biol Chem
, vol.275
, Issue.25
, pp. 19382-19388
-
-
Nguyen, D.H.1
-
29
-
-
0037022391
-
The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R
-
Resnati, M. et al. The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. Proc Natl Acad Sci U S A 2002, 99(3): 1359-64.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.3
, pp. 1359-1364
-
-
Resnati, M.1
-
30
-
-
0344507516
-
A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling
-
Wei, Y., Yang, X., Liu, Q., Wilkins, J.A. and Chapman, H.A. A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J Cell Biol 1999, 144(6): 1285-94.
-
(1999)
J Cell Biol
, vol.144
, Issue.6
, pp. 1285-1294
-
-
Wei, Y.1
Yang, X.2
Liu, Q.3
Wilkins, J.A.4
Chapman, H.A.5
-
31
-
-
0032478829
-
Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility
-
Nguyen, D.H., Hussaini, I.M. and Gonias, S.L. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. J Biol Chem 1998, 273(14): 8502-7.
-
(1998)
J Biol Chem
, vol.273
, Issue.14
, pp. 8502-8507
-
-
Nguyen, D.H.1
Hussaini, I.M.2
Gonias, S.L.3
-
32
-
-
1642373712
-
Tyrosine kinase, p56lck-induced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular signal regulated kinase pathways
-
Mahabeleshwar, G.H., Das, R. and Kundu G.C. Tyrosine kinase, p56lck-induced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular signal regulated kinase pathways. J Biol Chem 2004, 279(11): 9733-42.
-
(2004)
J Biol Chem
, vol.279
, Issue.11
, pp. 9733-9742
-
-
Mahabeleshwar, G.H.1
Das, R.2
Kundu, G.C.3
-
33
-
-
0032522751
-
Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction
-
Konakova, M., Hucho, F. and Schleuning, W.D. Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction. Eur J Biochem 1998, 253(2): 421-9.
-
(1998)
Eur J Biochem
, vol.253
, Issue.2
, pp. 421-429
-
-
Konakova, M.1
Hucho, F.2
Schleuning, W.D.3
-
34
-
-
0034687545
-
Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck)
-
Trigwell, S., Wood, L. and Jones, P. Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck). Biochem Biophys Res Commun 2000, 278(2): 440-6.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, Issue.2
, pp. 440-446
-
-
Trigwell, S.1
Wood, L.2
Jones, P.3
-
35
-
-
0032540943
-
The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells
-
Tang, H., Kerins, D.M., Hao, Q., Inagami, T. and Vaughan, D.E. The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells. J Biol Chem 1998, 273(29): 18268-72.
-
(1998)
J Biol Chem
, vol.273
, Issue.29
, pp. 18268-18272
-
-
Tang, H.1
Kerins, D.M.2
Hao, Q.3
Inagami, T.4
Vaughan, D.E.5
-
36
-
-
0031983177
-
The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells
-
Dumler, I., Weis, A., Mayboroda, O.A. et al. The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells. J Biol Chem 1998, 273(1): 315-21.
-
(1998)
J Biol Chem
, vol.273
, Issue.1
, pp. 315-321
-
-
Dumler, I.1
Weis, A.2
Mayboroda, O.A.3
-
37
-
-
0028334672
-
Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy
-
Waltz, D.A. and Chapman, H.A. Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy. J Biol Chem 1994, 269(20): 14746-50.
-
(1994)
J Biol Chem
, vol.269
, Issue.20
, pp. 14746-14750
-
-
Waltz, D.A.1
Chapman, H.A.2
-
38
-
-
0034678053
-
Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin
-
Sidenius, N. and Blasi, F. Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin. FEBS Lett 2000, 470(1): 40-6.
-
(2000)
FEBS Lett
, vol.470
, Issue.1
, pp. 40-46
-
-
Sidenius, N.1
Blasi, F.2
-
39
-
-
0037155875
-
Urokinase-dependent human vascular smooth muscle cells adhesion requires selective vitronectin phorphorylation by ecto-protein kinase CK2
-
Stepanova, V. et al. Urokinase-dependent human vascular smooth muscle cells adhesion requires selective vitronectin phorphorylation by ecto-protein kinase CK2. J Biol Chem 2000, 277(12): 10265-72.
-
(2000)
J Biol Chem
, vol.277
, Issue.12
, pp. 10265-10272
-
-
Stepanova, V.1
-
40
-
-
0025882214
-
An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines
-
Nusrat, A.R. and Chapman, H.A. An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines. J Clin Invest 1991, 87(3): 1091-7.
-
(1991)
J Clin Invest
, vol.87
, Issue.3
, pp. 1091-1097
-
-
Nusrat, A.R.1
Chapman, H.A.2
-
41
-
-
0029958368
-
Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells
-
Simon, D.I. et al. Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells. Blood 1996, 88(8): 3185-94.
-
(1996)
Blood
, vol.88
, Issue.8
, pp. 3185-3194
-
-
Simon, D.I.1
-
42
-
-
0034782160
-
Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells
-
Ma, Z., Webb, D.J., Jo, M. and Gonias, S.L. Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells. J Cell Sci 2001, 114(Pt. 18): 3387-96.
-
(2001)
J Cell Sci
, vol.114
, Issue.PART. 18
, pp. 3387-3396
-
-
Ma, Z.1
Webb, D.J.2
Jo, M.3
Gonias, S.L.4
-
43
-
-
0026643491
-
Structural requirements for the growth factor activity of the amino-terminal domain of urokinase
-
Rabbani, S.A. et al. Structural requirements for the growth factor activity of the amino-terminal domain of urokinase. J Biol Chem 1992, 267(20): 14151-6.
-
(1992)
J Biol Chem
, vol.267
, Issue.20
, pp. 14151-14156
-
-
Rabbani, S.A.1
-
44
-
-
0023603282
-
Proliferation of a human epidermal tumor cell line stimulated by urokinase
-
Kirchheimer, J.C., Wojta, J., Christ, G., Hienert, G. and Binder, B.R. Proliferation of a human epidermal tumor cell line stimulated by urokinase. FASEB J 1987, 1(2): 125-8.
-
(1987)
FASEB J
, vol.1
, Issue.2
, pp. 125-128
-
-
Kirchheimer, J.C.1
Wojta, J.2
Christ, G.3
Hienert, G.4
Binder, B.R.5
-
45
-
-
0030956119
-
Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy
-
Yu, W., Kim, J. and Ossowski, L. Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy. J Cell Biol 1997, 137(3): 767-77.
-
(1997)
J Cell Biol
, vol.137
, Issue.3
, pp. 767-777
-
-
Yu, W.1
Kim, J.2
Ossowski, L.3
-
46
-
-
0035172910
-
Urokinase receptor and fibronectin regulate the ERK (MAPK) to p38 (MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo
-
Aguirre-Ghiso, J.A., Liu, D., Mignatti, A., Kovalski, K. and Ossowski, L. Urokinase receptor and fibronectin regulate the ERK (MAPK) to p38 (MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo. Mol Biol Cell 2001, 12(4): 863-79.
-
(2001)
Mol Biol Cell
, vol.12
, Issue.4
, pp. 863-879
-
-
Aguirre-Ghiso, J.A.1
Liu, D.2
Mignatti, A.3
Kovalski, K.4
Ossowski, L.5
-
47
-
-
0002460807
-
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
-
Aguirre Ghiso, J.A., Kovalski, K. and Ossowski, L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J Cell Biol 1999, 147(1): 89-104.
-
(1999)
J Cell Biol
, vol.147
, Issue.1
, pp. 89-104
-
-
Aguirre Ghiso, J.A.1
Kovalski, K.2
Ossowski, L.3
-
48
-
-
16844386886
-
Plasminogen activation and cancer
-
Danø, K., Behrendt, N., Høyer-Hansen, G., Johnsen, M., Lund, L.R., Ploug, M., Rømer, J. Plasminogen activation and cancer. Thromb Haemost 2005, 93(4): 676-81.
-
(2005)
Thromb Haemost
, vol.93
, Issue.4
, pp. 676-681
-
-
Danø, K.1
Behrendt, N.2
Høyer-Hansen, G.3
Johnsen, M.4
Lund, L.R.5
Ploug, M.6
Rømer, J.7
-
49
-
-
0030662107
-
-
Bugge, T.H., Kombrinck, K.W., Xiao, Q., Holmba, ck.K.,Daugherty, C.C., Witte, D.P. and Degen, J.L. Growth and dissemination of Lewis lung carcinoma in plasminogen deficient mice. Blood 1997, 90(11): 4522-31.
-
Bugge, T.H., Kombrinck, K.W., Xiao, Q., Holmba, ck.K.,Daugherty, C.C., Witte, D.P. and Degen, J.L. Growth and dissemination of Lewis lung carcinoma in plasminogen deficient mice. Blood 1997, 90(11): 4522-31.
-
-
-
-
50
-
-
7344248988
-
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice
-
Bugge, T.H., Lund, L.R., Kombrinck, K.K. et al. Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice. Oncogene 1998, 16(24): 3097-104.
-
(1998)
Oncogene
, vol.16
, Issue.24
, pp. 3097-3104
-
-
Bugge, T.H.1
Lund, L.R.2
Kombrinck, K.K.3
-
51
-
-
0031902286
-
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
-
Bajou, K., Noel, A., Gerard, R.D. et al. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med 1998, 4(8): 923-8.
-
(1998)
Nat Med
, vol.4
, Issue.8
, pp. 923-928
-
-
Bajou, K.1
Noel, A.2
Gerard, R.D.3
-
52
-
-
0034667385
-
Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
-
Gutierrez, L.S., Schulman, A., Brito-Robinson, T., Noria, F., Ploplis, V.A. and Castellino, F.J. Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res 2000, 60: 5839-47.
-
(2000)
Cancer Res
, vol.60
, pp. 5839-5847
-
-
Gutierrez, L.S.1
Schulman, A.2
Brito-Robinson, T.3
Noria, F.4
Ploplis, V.A.5
Castellino, F.J.6
-
53
-
-
0030916499
-
Urokinase and the urokinase receptor: Association with in vitro invasiveness of human bladder cancer cell lines
-
Hudson, M.A. and McReynolds, L.M. Urokinase and the urokinase receptor: Association with in vitro invasiveness of human bladder cancer cell lines. J Natl Cancer Inst 1997, 89(10): 709-17.
-
(1997)
J Natl Cancer Inst
, vol.89
, Issue.10
, pp. 709-717
-
-
Hudson, M.A.1
McReynolds, L.M.2
-
54
-
-
0028567891
-
Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue
-
Plesner, T., Ralfkiaer, E., Wittrup, M. et al. Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue. Am J Clin Pathol 1994, 102(6): 835-41.
-
(1994)
Am J Clin Pathol
, vol.102
, Issue.6
, pp. 835-841
-
-
Plesner, T.1
Ralfkiaer, E.2
Wittrup, M.3
-
55
-
-
7844250487
-
Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells
-
Lanza, F., Castoldi, G.L., Castagnari, B. et al. Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells. Br J Haematol 1998, 103(1): 110-23.
-
(1998)
Br J Haematol
, vol.103
, Issue.1
, pp. 110-123
-
-
Lanza, F.1
Castoldi, G.L.2
Castagnari, B.3
-
56
-
-
0036596352
-
EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma
-
Liu, D., Ghiso, J.A., Estrada, Y. and Ossowski, L. EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma. Cancer Cell 2002, 1(5): 445-57.
-
(2002)
Cancer Cell
, vol.1
, Issue.5
, pp. 445-457
-
-
Liu, D.1
Ghiso, J.A.2
Estrada, Y.3
Ossowski, L.4
-
57
-
-
0002460807
-
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
-
Aguirre Ghiso, J.A., Kovalski, K. and Ossowski, L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J Cell Biol 1999, 147(1): 89-104.
-
(1999)
J Cell Biol
, vol.147
, Issue.1
, pp. 89-104
-
-
Aguirre Ghiso, J.A.1
Kovalski, K.2
Ossowski, L.3
-
58
-
-
24344507716
-
Wound-induced migration of MDA-MB-435 and SKOV-3 cancer cells is regulated by plasminogen activator inhibitor-1
-
Whitley, B.R. and Church, F.C. Wound-induced migration of MDA-MB-435 and SKOV-3 cancer cells is regulated by plasminogen activator inhibitor-1. Int J Oncol 2005, 27(3): 749-57.
-
(2005)
Int J Oncol
, vol.27
, Issue.3
, pp. 749-757
-
-
Whitley, B.R.1
Church, F.C.2
-
59
-
-
0033916675
-
Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro
-
Wilson, A.J. and Gibson, P.R. Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro. Gut 2000, 47(1): 105-11.
-
(2000)
Gut
, vol.47
, Issue.1
, pp. 105-111
-
-
Wilson, A.J.1
Gibson, P.R.2
-
60
-
-
33845230171
-
Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition
-
Oh, S.H., Lee, O.H., Schroeder, C.P. et al. Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition. Mol Cancer Ther 2006, 5(11): 2685-95.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.11
, pp. 2685-2695
-
-
Oh, S.H.1
Lee, O.H.2
Schroeder, C.P.3
-
61
-
-
33744933988
-
Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation
-
Madsen, M.A., Deryugina, E.I., Niessen, S., Cravatt, B.F. and Quigley, J.P. Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. J Biol Chem 2006, 281(23): 15997-6005.
-
(2006)
J Biol Chem
, vol.281
, Issue.23
, pp. 15997-16005
-
-
Madsen, M.A.1
Deryugina, E.I.2
Niessen, S.3
Cravatt, B.F.4
Quigley, J.P.5
-
62
-
-
33745246331
-
Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model
-
Merchan, J.R., Tang, J., Hu, G. et al. Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model. J Natl Cancer Inst 2006, 98(11): 756-64.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.11
, pp. 756-764
-
-
Merchan, J.R.1
Tang, J.2
Hu, G.3
-
63
-
-
0032910575
-
Blast cell surface and plasma soluble urokinase receptor in acute leukemia patients: Relationship to classification and response to therapy
-
Mustjoki, S., Alitalo, R., Stephens, R.W. and Vaheri, A. Blast cell surface and plasma soluble urokinase receptor in acute leukemia patients: Relationship to classification and response to therapy. Thromb Haemost 1999, 81(5): 705-10.
-
(1999)
Thromb Haemost
, vol.81
, Issue.5
, pp. 705-710
-
-
Mustjoki, S.1
Alitalo, R.2
Stephens, R.W.3
Vaheri, A.4
-
64
-
-
0030811592
-
Vitronectin binding to urokinase receptor in human breast cancer
-
Carriero, M.V., Del Vecchio, S., Franco, P. et al. Vitronectin binding to urokinase receptor in human breast cancer. Clin Cancer Res 1997, 3(8): 1299-308.
-
(1997)
Clin Cancer Res
, vol.3
, Issue.8
, pp. 1299-1308
-
-
Carriero, M.V.1
Del Vecchio, S.2
Franco, P.3
-
65
-
-
0032578687
-
Cancer cells overexpress mRNA of urokinase-type plasminogen activator, its receptor and inhibitors in human non-small-cell lung cancer tissue: Analysis by Northern blotting and in situ hybridization
-
Morita, S., Sato, A., Hayakawa, H. et al. Cancer cells overexpress mRNA of urokinase-type plasminogen activator, its receptor and inhibitors in human non-small-cell lung cancer tissue: Analysis by Northern blotting and in situ hybridization. Int J Cancer 1998, 78(3): 286-92.
-
(1998)
Int J Cancer
, vol.78
, Issue.3
, pp. 286-292
-
-
Morita, S.1
Sato, A.2
Hayakawa, H.3
-
66
-
-
0032529230
-
A urokinase receptor mRNA binding protein-mRNA interaction regulates receptor expression and function in human pleural mesothelioma cells
-
Shetty, S. and Idell, S. A urokinase receptor mRNA binding protein-mRNA interaction regulates receptor expression and function in human pleural mesothelioma cells. Arch BiochemBiophys 1998, 356(2): 265-79.
-
(1998)
Arch BiochemBiophys
, vol.356
, Issue.2
, pp. 265-279
-
-
Shetty, S.1
Idell, S.2
-
67
-
-
0030916499
-
Urokinase and the urokinase receptor: Association with in vitro invasiveness of human bladder cancer cell lines
-
Hudson, M.A. and McReynolds, L.M. Urokinase and the urokinase receptor: Association with in vitro invasiveness of human bladder cancer cell lines. J Natl Cancer Inst 1997, 89(10): 709-17.
-
(1997)
J Natl Cancer Inst
, vol.89
, Issue.10
, pp. 709-717
-
-
Hudson, M.A.1
McReynolds, L.M.2
-
68
-
-
0025853770
-
Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas
-
Pyke, C., Kristensen, P., Ralfkiaer, E. et al. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol 1991, 138(5): 1059-67.
-
(1991)
Am J Pathol
, vol.138
, Issue.5
, pp. 1059-1067
-
-
Pyke, C.1
Kristensen, P.2
Ralfkiaer, E.3
-
69
-
-
0032524046
-
Expression of urokinase-type plasminogen activator (u-PA), u-PA receptor, and tissue-type PA messenger RNAs in human hepatocellular carcinoma
-
De Petro, G., Tavian, D., Copeta, A., Portolani, N., Giulini, S.M. and Barlati, S. Expression of urokinase-type plasminogen activator (u-PA), u-PA receptor, and tissue-type PA messenger RNAs in human hepatocellular carcinoma. Cancer Res 1998, 58(10): 2234-9.
-
(1998)
Cancer Res
, vol.58
, Issue.10
, pp. 2234-2239
-
-
De Petro, G.1
Tavian, D.2
Copeta, A.3
Portolani, N.4
Giulini, S.M.5
Barlati, S.6
-
70
-
-
0032188909
-
Enhanced expression of urokinase receptor induced through the tissue factor-factor Vila pathway in human pancreatic cancer
-
Taniguchi, T., Kakkar, A.K., Tuddenham, E.G., Williamson, R.C. and Lemoine, N.R. Enhanced expression of urokinase receptor induced through the tissue factor-factor Vila pathway in human pancreatic cancer. Cancer Res 1998, 58(19): 4461-7.
-
(1998)
Cancer Res
, vol.58
, Issue.19
, pp. 4461-4467
-
-
Taniguchi, T.1
Kakkar, A.K.2
Tuddenham, E.G.3
Williamson, R.C.4
Lemoine, N.R.5
-
71
-
-
0027959035
-
Expression and localization of urokinase-type plasminogen activator receptor in human gliomas
-
Yamamoto, M., Sawaya, R., Mohanam, S. et al. Expression and localization of urokinase-type plasminogen activator receptor in human gliomas. Cancer Res 1994, 54(18): 5016-20.
-
(1994)
Cancer Res
, vol.54
, Issue.18
, pp. 5016-5020
-
-
Yamamoto, M.1
Sawaya, R.2
Mohanam, S.3
-
72
-
-
0036547696
-
Urokinase-type plasminogen activator: A potent marker of metastatic potential in human cancers
-
Duffy, M.J. Urokinase-type plasminogen activator: A potent marker of metastatic potential in human cancers. Biochem Soc Trans 2002, 30(2): 207-10.
-
(2002)
Biochem Soc Trans
, vol.30
, Issue.2
, pp. 207-210
-
-
Duffy, M.J.1
-
73
-
-
0036329424
-
Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: From pilot to level 1 evidence studies
-
Duffy, M.J. Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: From pilot to level 1 evidence studies. Clin Chem 2002, 48(8): 1194-7.
-
(2002)
Clin Chem
, vol.48
, Issue.8
, pp. 1194-1197
-
-
Duffy, M.J.1
-
74
-
-
0035918882
-
Randomized adjuvant chemotherapy trial in high-risk node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. German Chemotherapy Study Group
-
Janicke, F., Prechtl, A., Thomssen, C. et al. Randomized adjuvant chemotherapy trial in high-risk node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. German Chemotherapy Study Group. J Natl Cancer Inst 2001, 93(12): 913-20.
-
(2001)
J Natl Cancer Inst
, vol.93
, Issue.12
, pp. 913-920
-
-
Janicke, F.1
Prechtl, A.2
Thomssen, C.3
-
75
-
-
0037116616
-
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients
-
Look, M.P., van Putten, W.L.J., Duffy, M.J. et al. Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 2000, 94(2): 116-28.
-
(2000)
J Natl Cancer Inst
, vol.94
, Issue.2
, pp. 116-128
-
-
Look, M.P.1
van Putten, W.L.J.2
Duffy, M.J.3
-
76
-
-
0023735157
-
Urokinase-plasminogen activator, a marker for aggressive breast cancer. Preliminary report
-
Duffy, M.J., O'Grady, P., Devaney, D., O'Siorain, L., Fennelly, J.J. and Lijnen, H.J. Urokinase-plasminogen activator, a marker for aggressive breast cancer. Preliminary report. Cancer 1988, 62(3): 531-3.
-
(1988)
Cancer
, vol.62
, Issue.3
, pp. 531-533
-
-
Duffy, M.J.1
O'Grady, P.2
Devaney, D.3
O'Siorain, L.4
Fennelly, J.J.5
Lijnen, H.J.6
-
77
-
-
0031778389
-
Urokinase plasminogen activator: A prognostic marker in breast cancer including patients with axillary node-negative disease
-
Duffy, M.J., Duggan, C., Mulcahy, H.E., McDermott, E.W. and O'Higgins, N.J. Urokinase plasminogen activator: A prognostic marker in breast cancer including patients with axillary node-negative disease. Clin Chem 1998, 44(6 Pt. 1): 1177-83.
-
(1998)
Clin Chem
, vol.44
, Issue.6 PART. 1
, pp. 1177-1183
-
-
Duffy, M.J.1
Duggan, C.2
Mulcahy, H.E.3
McDermott, E.W.4
O'Higgins, N.J.5
-
78
-
-
0029065722
-
Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer
-
Duggan, C., Maguire, T., McDermott, E., O'Higgins, N., Fennelly, J.J. and Duffy, M.J. Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer. Int J Cancer 1995, 61(5): 597-600.
-
(1995)
Int J Cancer
, vol.61
, Issue.5
, pp. 597-600
-
-
Duggan, C.1
Maguire, T.2
McDermott, E.3
O'Higgins, N.4
Fennelly, J.J.5
Duffy, M.J.6
-
79
-
-
0023244770
-
Plasminogen activators and tumor development in the human colon: Activity levels in normal mucosa, adenomatous polyps, and adenocarcinomas
-
De Bruin, P.A., Griffioen, G., Verspaget, H.W. et al. Plasminogen activators and tumor development in the human colon: Activity levels in normal mucosa, adenomatous polyps, and adenocarcinomas: Cancer Res 1987, 47(17): 4654-7.
-
(1987)
Cancer Res
, vol.47
, Issue.17
, pp. 4654-4657
-
-
De Bruin, P.A.1
Griffioen, G.2
Verspaget, H.W.3
-
80
-
-
0030801567
-
Urokinase-type plasminogen activator in colorectal cancer: Relationship with clinicopathological features and patient outcome
-
Skelly, M.M., Troy, A., Duffy, M.J. et al. Urokinase-type plasminogen activator in colorectal cancer: Relationship with clinicopathological features and patient outcome. Clin Cancer Res 1997, 3(10): 1837-40.
-
(1997)
Clin Cancer Res
, vol.3
, Issue.10
, pp. 1837-1840
-
-
Skelly, M.M.1
Troy, A.2
Duffy, M.J.3
-
81
-
-
0344549386
-
The role of cysteine and serine proteases in colorectal carcinoma
-
Herszenyi, L., Plebani, M., Carraro, P. et al. The role of cysteine and serine proteases in colorectal carcinoma. Cancer 1999, 86(7): 1135-42.
-
(1999)
Cancer
, vol.86
, Issue.7
, pp. 1135-1142
-
-
Herszenyi, L.1
Plebani, M.2
Carraro, P.3
-
82
-
-
0032833646
-
Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization
-
Harvey, S.R., Sait, S.N., Xu, Y. et al. Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization. Am J Pathol 1999, 155(4): 1115-20.
-
(1999)
Am J Pathol
, vol.155
, Issue.4
, pp. 1115-1120
-
-
Harvey, S.R.1
Sait, S.N.2
Xu, Y.3
-
83
-
-
0027971923
-
Antigen expression associated with lymph node metastasis in gastric adenocarcinomas
-
Wang, S.N., Miyauchi, M., Koshikawa, N. et al. Antigen expression associated with lymph node metastasis in gastric adenocarcinomas. Pathol Int 1994, 44(12): 844-9.
-
(1994)
Pathol Int
, vol.44
, Issue.12
, pp. 844-849
-
-
Wang, S.N.1
Miyauchi, M.2
Koshikawa, N.3
-
84
-
-
0041436787
-
Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma
-
Cantero, D., Friess, H., Deflorin, J. et al. Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma. Thromb Haemost 1997, 77: 62-70.
-
(1997)
Thromb Haemost
, vol.77
, pp. 62-70
-
-
Cantero, D.1
Friess, H.2
Deflorin, J.3
-
85
-
-
0030914794
-
Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity
-
Park, I.K., Kim, B.J., Goh, Y.J. et al. Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity. Int J Cancer 1997, 71(5): 867-73.
-
(1997)
Int J Cancer
, vol.71
, Issue.5
, pp. 867-873
-
-
Park, I.K.1
Kim, B.J.2
Goh, Y.J.3
-
86
-
-
0028075066
-
Urokinase receptor and colorectal cancer survival [letter]
-
Ganesh, S., Sier, C.F., Heerding, M.M. et al. Urokinase receptor and colorectal cancer survival [letter]. Lancet 1994, 344(8919): 401-2.
-
(1994)
Lancet
, vol.344
, Issue.8919
, pp. 401-402
-
-
Ganesh, S.1
Sier, C.F.2
Heerding, M.M.3
-
87
-
-
0033583761
-
Plasma urokinase receptor levels in patients with colorectal cancer: Relationship to prognosis
-
Stephens, R.W., Nielsen, H.J., Christensen, I.J. et al. Plasma urokinase receptor levels in patients with colorectal cancer: Relationship to prognosis. J Natl Cancer Inst 1999, 91(10): 869-74.
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.10
, pp. 869-874
-
-
Stephens, R.W.1
Nielsen, H.J.2
Christensen, I.J.3
-
88
-
-
7844244311
-
Urokinase type plasminogen activator receptor expression in colorectal neoplasms
-
Suzuki, S., Hayashi, Y., Wang, Y. et al. Urokinase type plasminogen activator receptor expression in colorectal neoplasms. Gut 1998, 43(6): 798-805.
-
(1998)
Gut
, vol.43
, Issue.6
, pp. 798-805
-
-
Suzuki, S.1
Hayashi, Y.2
Wang, Y.3
-
89
-
-
0031766825
-
Urokinase receptor is a key player in tumour progression
-
Taniguchi, T., Lemoine, N.R. and Kakkar, A.K. Urokinase receptor is a key player in tumour progression. Gut 1998, 43(6): 739-40.
-
(1998)
Gut
, vol.43
, Issue.6
, pp. 739-740
-
-
Taniguchi, T.1
Lemoine, N.R.2
Kakkar, A.K.3
-
90
-
-
0025983254
-
Imbalance of plasminogen activators and their inhibitors in human colorectal neoplasia: Implications of urokinase in colorectal carcinogenesis
-
Sier, C.F., Verspaget, H.W., Griffioen, G. et al. Imbalance of plasminogen activators and their inhibitors in human colorectal neoplasia: Implications of urokinase in colorectal carcinogenesis. Gastroenterology 1991, 101(6): 1522-8.
-
(1991)
Gastroenterology
, vol.101
, Issue.6
, pp. 1522-1528
-
-
Sier, C.F.1
Verspaget, H.W.2
Griffioen, G.3
-
91
-
-
0028081298
-
Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis
-
Sier, C.F., Vloedgraven, H.J., Ganesh, S. et al. Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis. Gastroenterology 1994, 107(5): 1449-56.
-
(1994)
Gastroenterology
, vol.107
, Issue.5
, pp. 1449-1456
-
-
Sier, C.F.1
Vloedgraven, H.J.2
Ganesh, S.3
-
92
-
-
0031902286
-
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
-
Bajou, K., Noel, A., Gerard, R.D. et al. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med 1998, 4(8): 923-8.
-
(1998)
Nat Med
, vol.4
, Issue.8
, pp. 923-928
-
-
Bajou, K.1
Noel, A.2
Gerard, R.D.3
-
93
-
-
0033573059
-
Larger and more invasive colorectal carcinoma contains larger amounts of plasminogen activator inhibitor type 1 and its relative ratio over urokinase receptor correlates well with tumor size
-
Abe, J., Urano, T., Konno, H. et al. Larger and more invasive colorectal carcinoma contains larger amounts of plasminogen activator inhibitor type 1 and its relative ratio over urokinase receptor correlates well with tumor size. Cancer 1999, 86(12): 2602-11.
-
(1999)
Cancer
, vol.86
, Issue.12
, pp. 2602-2611
-
-
Abe, J.1
Urano, T.2
Konno, H.3
-
94
-
-
0028277928
-
High-affinity urokinase receptor antagonists identified with bacteriophage peptide display
-
Goodson, R.J, Doyle, M.V., Kaufman, S.E. and Rosenberg, S. High-affinity urokinase receptor antagonists identified with bacteriophage peptide display. Proc Natl Acad Sci U S A 1994, 91(15): 7129-33.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.15
, pp. 7129-7133
-
-
Goodson, R.J.1
Doyle, M.V.2
Kaufman, S.E.3
Rosenberg, S.4
-
95
-
-
0033491126
-
Increased levels of urokinase receptor in plasma of head and neck squamous cell carcinoma patients
-
Schmidt, M. and Hoppe, F. Increased levels of urokinase receptor in plasma of head and neck squamous cell carcinoma patients. Acta Otolaryngol 1999, 119(8): 949-53.
-
(1999)
Acta Otolaryngol
, vol.119
, Issue.8
, pp. 949-953
-
-
Schmidt, M.1
Hoppe, F.2
-
96
-
-
0030799620
-
Elevated plasma levels of urokinase plasminogen activator receptor in non-small cell lung cancer patients
-
Pappot, H., Høyer-Hansen, G, Rønne, E. et al. Elevated plasma levels of urokinase plasminogen activator receptor in non-small cell lung cancer patients. Eur J Cancer 1997, 33(6): 867-72.
-
(1997)
Eur J Cancer
, vol.33
, Issue.6
, pp. 867-872
-
-
Pappot, H.1
Høyer-Hansen, G.2
Rønne, E.3
-
97
-
-
0032080905
-
The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients
-
Sier, C.F., Stephens, R., Bizik, J. et al. The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients. Cancer Res 1998, 58(9): 1843-9.
-
(1998)
Cancer Res
, vol.58
, Issue.9
, pp. 1843-1849
-
-
Sier, C.F.1
Stephens, R.2
Bizik, J.3
-
98
-
-
0033119221
-
Elevation of serum levels of urokinase-type plasminogen activator and its receptor is associated with disease progression and prognosis in patients with prostate cancer
-
Miyake, H., Hara, I., Yamanaka, K., Gohji, K., Arakawa, S. and Kamidono, S. Elevation of serum levels of urokinase-type plasminogen activator and its receptor is associated with disease progression and prognosis in patients with prostate cancer. Prostate 1999, 39(2): 123-9.
-
(1999)
Prostate
, vol.39
, Issue.2
, pp. 123-129
-
-
Miyake, H.1
Hara, I.2
Yamanaka, K.3
Gohji, K.4
Arakawa, S.5
Kamidono, S.6
-
99
-
-
0035086985
-
Prognostic importance of the soluble plasminogen activator receptor, suPAR, in plasma from rectal cancer patients
-
Fernebro, E., Madsen, R.R., Ferno, M. et al. Prognostic importance of the soluble plasminogen activator receptor, suPAR, in plasma from rectal cancer patients. Eur J Cancer 2001, 37(4): 486-91.
-
(2001)
Eur J Cancer
, vol.37
, Issue.4
, pp. 486-491
-
-
Fernebro, E.1
Madsen, R.R.2
Ferno, M.3
-
100
-
-
0028287392
-
Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor like domain of urokinase in the experimental and spontaneous metastasis model
-
Kobayashi, H., Gotoh, J., Fujie, M., Shinohara, H., Moniwa, N. and Terao, T. Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor like domain of urokinase in the experimental and spontaneous metastasis model. Int J Cancer 1995, 57(5): 727-33.
-
(1995)
Int J Cancer
, vol.57
, Issue.5
, pp. 727-733
-
-
Kobayashi, H.1
Gotoh, J.2
Fujie, M.3
Shinohara, H.4
Moniwa, N.5
Terao, T.6
-
101
-
-
0027283371
-
Prevention of metastasis by inhibition of the urokinase receptor
-
Crowley, C.W., Cohen, R.L., Lucas, B.K., Liu, G., Shuman, M.A. and Levinson, A.D. Prevention of metastasis by inhibition of the urokinase receptor. Proc Natl Acad Sci U S A 1993, 90(11): 5021-5.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.11
, pp. 5021-5025
-
-
Crowley, C.W.1
Cohen, R.L.2
Lucas, B.K.3
Liu, G.4
Shuman, M.A.5
Levinson, A.D.6
-
102
-
-
3042755194
-
Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth
-
Lefesvre, P., Attema, J. and van Bekkum, D. Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth. BMC Cancer 2002, 2: 17.
-
(2002)
BMC Cancer
, vol.2
, pp. 17
-
-
Lefesvre, P.1
Attema, J.2
van Bekkum, D.3
-
103
-
-
0028910195
-
Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumour cell invasion in vitro
-
Kobayashi, H., Gotoh, J., Hirashima, Y., Fujie, M., Sugino, D. and Terao, T. Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumour cell invasion in vitro. J Biol Chem 1995, 270(14): 8361-6.
-
(1995)
J Biol Chem
, vol.270
, Issue.14
, pp. 8361-8366
-
-
Kobayashi, H.1
Gotoh, J.2
Hirashima, Y.3
Fujie, M.4
Sugino, D.5
Terao, T.6
-
104
-
-
0032079489
-
A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumour cell invasion and metastasis
-
Kobayashi, H., Sugino, D., She, M.Y. et al. A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumour cell invasion and metastasis. Eur J Biochem 1998, 253(3): 817-26.
-
(1998)
Eur J Biochem
, vol.253
, Issue.3
, pp. 817-826
-
-
Kobayashi, H.1
Sugino, D.2
She, M.Y.3
-
105
-
-
0001453577
-
Urokinase receptor antagonists inhibit angiogenesis and primary tumour growth in syngeneic mice
-
Min, H.Y., Doyle, L.V., Vitt, C.R., Zandonella, C.L., Stratton-Thomas, J.R., Shuman, M.A. and Rosenberg, S. Urokinase receptor antagonists inhibit angiogenesis and primary tumour growth in syngeneic mice. Cancer Res 1996, 56(10): 2428-33.
-
(1996)
Cancer Res
, vol.56
, Issue.10
, pp. 2428-2433
-
-
Min, H.Y.1
Doyle, L.V.2
Vitt, C.R.3
Zandonella, C.L.4
Stratton-Thomas, J.R.5
Shuman, M.A.6
Rosenberg, S.7
-
106
-
-
0034843783
-
Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo
-
van der Pluijm, G., Sijmons, B., Vloedgraven, H. et al. Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo. Am J Pathol 2001, 159(3): 971-82.
-
(2001)
Am J Pathol
, vol.159
, Issue.3
, pp. 971-982
-
-
van der Pluijm, G.1
Sijmons, B.2
Vloedgraven, H.3
-
107
-
-
0037008781
-
Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization
-
Sidenius, N., Andolfo, A., Fesce, R. and Blasi, F. Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization. J Biol Chem 2002, 277(31): 27982-90.
-
(2002)
J Biol Chem
, vol.277
, Issue.31
, pp. 27982-27990
-
-
Sidenius, N.1
Andolfo, A.2
Fesce, R.3
Blasi, F.4
-
108
-
-
0033951758
-
The insulin-like growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: A new avenue for breast cancer therapy
-
Dunn, S.E., Torres, J.V., Nihei, N. and Barrett, J.C. The insulin-like growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: A new avenue for breast cancer therapy. Mol Carcinog 2000, 27(1): 10-7.
-
(2000)
Mol Carcinog
, vol.27
, Issue.1
, pp. 10-17
-
-
Dunn, S.E.1
Torres, J.V.2
Nihei, N.3
Barrett, J.C.4
-
109
-
-
0028208912
-
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells
-
Zou, Z., Anisowicz, A., Hendrix, M.J. et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 1994, 263(5146): 526-9.
-
(1994)
Science
, vol.263
, Issue.5146
, pp. 526-529
-
-
Zou, Z.1
Anisowicz, A.2
Hendrix, M.J.3
-
110
-
-
0037596571
-
Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis
-
Cher, M.L., Biliran, H.R. Jr., Bhagat, S. et al. Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis. Proc Natl Acad Sci U S A 2003, 100(13): 7847-52.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.13
, pp. 7847-7852
-
-
Cher, M.L.1
Biliran Jr., H.R.2
Bhagat, S.3
-
111
-
-
33646271356
-
Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase- type plasminogen activator receptor system
-
Yin, S., Lockett, J., Meng, Y. et al. Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase- type plasminogen activator receptor system. Cancer Res 2006, 66(8): 4173-81.
-
(2006)
Cancer Res
, vol.66
, Issue.8
, pp. 4173-4181
-
-
Yin, S.1
Lockett, J.2
Meng, Y.3
-
112
-
-
0025900910
-
The lig and-binding domain of the cell surface receptor for urokinase-type plasminogen activator
-
Behrendt, N., Ploug, M., Patthy, L., Houen, G., Blasi, F. and Danø, K. The lig and-binding domain of the cell surface receptor for urokinase-type plasminogen activator. J Biol Chem 1991, 266(12): 7842-7.
-
(1991)
J Biol Chem
, vol.266
, Issue.12
, pp. 7842-7847
-
-
Behrendt, N.1
Ploug, M.2
Patthy, L.3
Houen, G.4
Blasi, F.5
Danø, K.6
-
113
-
-
0027217194
-
Localization of the disulfide bonds in the NH2- terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchoredanchored membrane proteins
-
Ploug, M., Kjalke, M, Rønne, E., Weidle, U., Høyer-Hansen, G. and Danø, K. Localization of the disulfide bonds in the NH2- terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchoredanchored membrane proteins. J Biol Chem 1993, 268(23): 17539-46.
-
(1993)
J Biol Chem
, vol.268
, Issue.23
, pp. 17539-17546
-
-
Ploug, M.1
Kjalke, M.2
Rønne, E.3
Weidle, U.4
Høyer-Hansen, G.5
Danø, K.6
-
114
-
-
0035947634
-
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin
-
Liu, S, Bugge, T.H. and Leppla, S.H. Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin. J Biol Chem 2001, 276(21): 17976-84.
-
(2001)
J Biol Chem
, vol.276
, Issue.21
, pp. 17976-17984
-
-
Liu, S.1
Bugge, T.H.2
Leppla, S.H.3
-
115
-
-
37249048769
-
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator (uPA)
-
Pulukuri, S.M., Gorantla, B. and Rao, J.S. Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator (uPA). J Biol Chem 2007, 282(49): 35594-603.
-
(2007)
J Biol Chem
, vol.282
, Issue.49
, pp. 35594-35603
-
-
Pulukuri, S.M.1
Gorantla, B.2
Rao, J.S.3
-
116
-
-
33845771171
-
The urokinase plasminogen activator receptor as a gene therapy target for cancer
-
Pillay, V., Dass, C.R. and Choong, P.F. The urokinase plasminogen activator receptor as a gene therapy target for cancer. Trends Biotechnol 2007, 25(1): 33-9.
-
(2007)
Trends Biotechnol
, vol.25
, Issue.1
, pp. 33-39
-
-
Pillay, V.1
Dass, C.R.2
Choong, P.F.3
-
117
-
-
0033565613
-
Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth
-
Mohan, P.M., Chintala, S.K., Mohanam, S. et al. Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. Cancer Res 1999, 59(14): 3369-73.
-
(1999)
Cancer Res
, vol.59
, Issue.14
, pp. 3369-3373
-
-
Mohan, P.M.1
Chintala, S.K.2
Mohanam, S.3
-
118
-
-
0034220765
-
A novel role for the urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas
-
Kin, Y., Chintala, S.K., Go, Y. et al. A novel role for the urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas. Int J Oncol 2000, 17(1): 61-5.
-
(2000)
Int J Oncol
, vol.17
, Issue.1
, pp. 61-65
-
-
Kin, Y.1
Chintala, S.K.2
Go, Y.3
-
119
-
-
0034906667
-
Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines
-
Lakka, S.S., Rajagopal, R., Rajan, M.K. et al. Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. Clin Cancer Res 2001, 7(4): 1087-93.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.4
, pp. 1087-1093
-
-
Lakka, S.S.1
Rajagopal, R.2
Rajan, M.K.3
-
120
-
-
0035871975
-
Inhibition of colon cancer metastasis by a 3′-end antisense urokinase receptor mRNA in a nude mouse model
-
Wang, Y., Liang, X., Wu, S., Murrell, G.A. and Doe, W.F. Inhibition of colon cancer metastasis by a 3′-end antisense urokinase receptor mRNA in a nude mouse model. Int J Cancer 2001, 92(2): 257-62.
-
(2001)
Int J Cancer
, vol.92
, Issue.2
, pp. 257-262
-
-
Wang, Y.1
Liang, X.2
Wu, S.3
Murrell, G.A.4
Doe, W.F.5
-
121
-
-
0032479278
-
Antisense inhibition of urokinase: Effect on malignancy in a human osteosarcoma cell line
-
Haeckel, C., Krueger, S. and Roessner, A. Antisense inhibition of urokinase: Effect on malignancy in a human osteosarcoma cell line. Int J Cancer 1998, 77(1): 153-60.
-
(1998)
Int J Cancer
, vol.77
, Issue.1
, pp. 153-160
-
-
Haeckel, C.1
Krueger, S.2
Roessner, A.3
-
122
-
-
0034885886
-
Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells
-
Mohanam, S., Jasti, S.L., Kondraganti, S.R. et al. Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells. Clin Cancer Res 2001, 7(8): 2519-26.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.8
, pp. 2519-2526
-
-
Mohanam, S.1
Jasti, S.L.2
Kondraganti, S.R.3
-
123
-
-
0141841681
-
Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
-
Gondi, C.S., Lakka, S.S., Yanamandra, N. et al. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Oncogene 2003, 22(38): 5967-75.
-
(2003)
Oncogene
, vol.22
, Issue.38
, pp. 5967-5975
-
-
Gondi, C.S.1
Lakka, S.S.2
Yanamandra, N.3
-
124
-
-
0038181212
-
Synergistic down-regulation of uroki nase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth
-
Lakka, S.S., Gondi, C.S., Yanamandra, N. et al. Synergistic down-regulation of uroki nase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth. Cancer Res 2003, 63(10): 2454-61.
-
(2003)
Cancer Res
, vol.63
, Issue.10
, pp. 2454-2461
-
-
Lakka, S.S.1
Gondi, C.S.2
Yanamandra, N.3
-
125
-
-
33644683515
-
Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells
-
Rao, J.S., Gondi, C., Chetty, C., Chittivelu, S., Joseph, P.A. and Lakka, S.S. Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells. Mol Cancer Ther 2005, 4(9): 1399-408.
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.9
, pp. 1399-1408
-
-
Rao, J.S.1
Gondi, C.2
Chetty, C.3
Chittivelu, S.4
Joseph, P.A.5
Lakka, S.S.6
-
126
-
-
3042551389
-
Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas
-
Gondi, C.S., Lakka, S.S., Yanamandra, N. et al. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res 2004, 64(12): 4069-77.
-
(2004)
Cancer Res
, vol.64
, Issue.12
, pp. 4069-4077
-
-
Gondi, C.S.1
Lakka, S.S.2
Yanamandra, N.3
-
127
-
-
0029007784
-
Antisense inhibition of urokinase reduces spread of human ovarian cancer in mice
-
Wilhelm, O., Schmitt, M., Hohl, S., Senekowitsch, R. and Graeff, H. Antisense inhibition of urokinase reduces spread of human ovarian cancer in mice. Clin Exp Metastasis 1995, 13(4): 296-302.
-
(1995)
Clin Exp Metastasis
, vol.13
, Issue.4
, pp. 296-302
-
-
Wilhelm, O.1
Schmitt, M.2
Hohl, S.3
Senekowitsch, R.4
Graeff, H.5
-
128
-
-
0028917857
-
Reversion of the invasive phenotype of transformed human fibroblasts by anti-messenger oligonucleotide inhibition of urokinase receptor gene expression
-
Quattrone, A., Fibbi, G., Anichini, E. et al. Reversion of the invasive phenotype of transformed human fibroblasts by anti-messenger oligonucleotide inhibition of urokinase receptor gene expression. Cancer Res 1995, 55(1): 90-5.
-
(1995)
Cancer Res
, vol.55
, Issue.1
, pp. 90-95
-
-
Quattrone, A.1
Fibbi, G.2
Anichini, E.3
-
129
-
-
0030583608
-
Urokinase antisense oligodeoxynucleotides as a novel therapeutic agent for malignant glioma: In vitro and in vivo studies of uptake, effects and toxicity
-
Engelhard, H., Narang, C., Homer, R. and Duncan, H. Urokinase antisense oligodeoxynucleotides as a novel therapeutic agent for malignant glioma: in vitro and in vivo studies of uptake, effects and toxicity. Biochem Biophys Res Commun 1996, 227(2): 400-5.
-
(1996)
Biochem Biophys Res Commun
, vol.227
, Issue.2
, pp. 400-405
-
-
Engelhard, H.1
Narang, C.2
Homer, R.3
Duncan, H.4
-
130
-
-
11144358203
-
Antisense oligodeoxynucleotides for urokinase-plasminogen activator receptor have anti-invasive and anti-proliferative effects in vitro and inhibit spontaneous metastases of human melanoma in mice
-
D'Alessio, S,, Margheri, F,, Pucci, M. et al. Antisense oligodeoxynucleotides for urokinase-plasminogen activator receptor have anti-invasive and anti-proliferative effects in vitro and inhibit spontaneous metastases of human melanoma in mice. Int J Cancer 2004, 110(1): 125-33.
-
(2004)
Int J Cancer
, vol.110
, Issue.1
, pp. 125-133
-
-
D'Alessio, S.1
Margheri, F.2
Pucci, M.3
-
131
-
-
20244381689
-
Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases
-
Margheri, F., D'Alessio, S., Serrati, S. et al. Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases. Gene Ther 2005, 12(8): 702-14.
-
(2005)
Gene Ther
, vol.12
, Issue.8
, pp. 702-714
-
-
Margheri, F.1
D'Alessio, S.2
Serrati, S.3
-
132
-
-
26444486892
-
Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor
-
Nozaki, S., Endo, Y., Nakahara, H. et al. Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor. Oral Oncol 2005, 41(10): 971-97.
-
(2005)
Oral Oncol
, vol.41
, Issue.10
, pp. 971-997
-
-
Nozaki, S.1
Endo, Y.2
Nakahara, H.3
-
133
-
-
34548586960
-
RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis
-
Tummalapalli, P., Gondi, C.S., Dinh, D.H., Gujrati, M. and Rao, J.S. RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis. Int J Oncol 2007, 31(1): 5-17.
-
(2007)
Int J Oncol
, vol.31
, Issue.1
, pp. 5-17
-
-
Tummalapalli, P.1
Gondi, C.S.2
Dinh, D.H.3
Gujrati, M.4
Rao, J.S.5
-
134
-
-
34547134691
-
Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice
-
Gondi, C.S., Lakka, S.S., Dinh, D.H., Olivero, W.C., Gujrati, M. and Rao, J.S. Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Clin Cancer Res 2007, 13(14): 4051-60.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.14
, pp. 4051-4060
-
-
Gondi, C.S.1
Lakka, S.S.2
Dinh, D.H.3
Olivero, W.C.4
Gujrati, M.5
Rao, J.S.6
-
135
-
-
27744435789
-
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo
-
Pulukuri, S.M., Gondi, C.S., Lakka, S.S. et al. RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. J Biol Chem 2005, 280(43): 36529-40.
-
(2005)
J Biol Chem
, vol.280
, Issue.43
, pp. 36529-36540
-
-
Pulukuri, S.M.1
Gondi, C.S.2
Lakka, S.S.3
-
136
-
-
0036431989
-
Inhibitors of the protease domain of urokinase-type plasminogen activator
-
Rockway, T.W., Nienaber, V. and Giranda, V.L. Inhibitors of the protease domain of urokinase-type plasminogen activator. Curr Pharm Des 2002, 8(28): 2541-58.
-
(2002)
Curr Pharm Des
, vol.8
, Issue.28
, pp. 2541-2558
-
-
Rockway, T.W.1
Nienaber, V.2
Giranda, V.L.3
-
137
-
-
14444287267
-
Protein kinase C-dependent in vivo phosphorylation of prourokinase leads to the formation of a receptor competitive antagonist
-
Franco, P., Massa, O., Garcia-Rocha, M. et al. Protein kinase C-dependent in vivo phosphorylation of prourokinase leads to the formation of a receptor competitive antagonist. J Biol Chem 1998, 273(42): 27734-40.
-
(1998)
J Biol Chem
, vol.273
, Issue.42
, pp. 27734-27740
-
-
Franco, P.1
Massa, O.2
Garcia-Rocha, M.3
-
138
-
-
0035408087
-
Interference with the urokinase plasminogen activator system: A promising therapy concept for solid tumours
-
Muehlenweg, B., Sperl, S., Magdolen, V., Schmitt, M. and Harbeck, N. Interference with the urokinase plasminogen activator system: A promising therapy concept for solid tumours. Expert Opin Biol Ther 2001, 1(4): 683-91.
-
(2001)
Expert Opin Biol Ther
, vol.1
, Issue.4
, pp. 683-691
-
-
Muehlenweg, B.1
Sperl, S.2
Magdolen, V.3
Schmitt, M.4
Harbeck, N.5
-
139
-
-
0037025460
-
2-(2-Hydroxy-3- alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors
-
Mackman, R.L., Hui, H.C., Breitenbucher, J.G. et al. 2-(2-Hydroxy-3- alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors. Bioorg Med Chem Lett 2002, 12(15): 2019-22.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, Issue.15
, pp. 2019-2022
-
-
Mackman, R.L.1
Hui, H.C.2
Breitenbucher, J.G.3
-
140
-
-
0027861314
-
The synthesis of three 4-substituted benzo[b]thiophene-2-carboxamidines as potent and selective inhibitors of urokinase
-
Bridges, A.J., Lee, A., Schwartz, C.E., Towle, M.J. and Littlefield, B.A. The synthesis of three 4-substituted benzo[b]thiophene-2-carboxamidines as potent and selective inhibitors of urokinase. Bioorg Med Chem 1993, 1(6): 403-10.
-
(1993)
Bioorg Med Chem
, vol.1
, Issue.6
, pp. 403-410
-
-
Bridges, A.J.1
Lee, A.2
Schwartz, C.E.3
Towle, M.J.4
Littlefield, B.A.5
-
141
-
-
2442618968
-
Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 3: 1-isoquinolinylguanidines
-
Barber, C.G., Dickinson, R.P. and Fish, P.V. Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 3: 1-isoquinolinylguanidines. Bioorg Med Chem Lett 2004, 14(12): 3227-30.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.12
, pp. 3227-3230
-
-
Barber, C.G.1
Dickinson, R.P.2
Fish, P.V.3
-
142
-
-
33745115242
-
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator
-
Heynekamp, J.J., Hunsaker, L.A., Vander Jagt, T.A., Deck, L.M. and Vander Jagt, D.L. Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator. BMC Chem Biol 2006, 6: 1.
-
(2006)
BMC Chem Biol
, vol.6
, pp. 1
-
-
Heynekamp, J.J.1
Hunsaker, L.A.2
Vander Jagt, T.A.3
Deck, L.M.4
Vander Jagt, D.L.5
-
143
-
-
20144386978
-
Suppression of rat breast cancer metastasis and reduction of primary tumour growth by the small syn thetic urokinase inhibitor WX-UK1
-
Setyono-Han, B., Sturzebecher, J., Schmalix, W.A. et al. Suppression of rat breast cancer metastasis and reduction of primary tumour growth by the small syn thetic urokinase inhibitor WX-UK1. Thromb Haemost 2005, 93(4): 779-86.
-
(2005)
Thromb Haemost
, vol.93
, Issue.4
, pp. 779-786
-
-
Setyono-Han, B.1
Sturzebecher, J.2
Schmalix, W.A.3
-
144
-
-
0023646314
-
Amiloride selectively inhibits the urokinase-type plasminogen activator
-
Vassalli, J.D. and Belin, D. Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS Lett 1987, 214(1): 187-91.
-
(1987)
FEBS Lett
, vol.214
, Issue.1
, pp. 187-191
-
-
Vassalli, J.D.1
Belin, D.2
-
145
-
-
0034624980
-
(4-Aminomethyl) phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase
-
Sperl, S., Jacob, U., Arroyo de Prada, N. et al. (4-Aminomethyl) phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. Proc Natl Acad Sci U S A 2000, 97(10): 5113-8.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.10
, pp. 5113-5118
-
-
Sperl, S.1
Jacob, U.2
Arroyo de Prada, N.3
-
146
-
-
0033231047
-
3-Amidinophenylalanine-based inhibitors of urokinase
-
Ertongur, S., Lang, S., Mack, B. et al. 3-Amidinophenylalanine-based inhibitors of urokinase. Bioorg Med Chem Lett 1999, 9: 3147-52.
-
(1999)
Bioorg Med Chem Lett
, vol.9
, pp. 3147-3152
-
-
Ertongur, S.1
Lang, S.2
Mack, B.3
-
148
-
-
2942591963
-
Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system
-
Ertongur, S., Lang, S., Mack, B., Wosikowski, K., Muehlenweg, B. and Gires, O. Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system. Int J Cancer 2004, 110(6): 815-24.
-
(2004)
Int J Cancer
, vol.110
, Issue.6
, pp. 815-824
-
-
Ertongur, S.1
Lang, S.2
Mack, B.3
Wosikowski, K.4
Muehlenweg, B.5
Gires, O.6
-
149
-
-
43049151282
-
-
Wosikowski, K., Foekens, J., Setyono-Han, B., Stürzebecher, J., Tscheche, H. and Schmalix, W. Antimetastatic efficacy of WX-UK1 in a resected, spontaneously metastasizing rat mammary tumor model. Proc Am Assoc Cancer Res (AACR) 2002, 43: Abst. 788.
-
Wosikowski, K., Foekens, J., Setyono-Han, B., Stürzebecher, J., Tscheche, H. and Schmalix, W. Antimetastatic efficacy of WX-UK1 in a resected, spontaneously metastasizing rat mammary tumor model. Proc Am Assoc Cancer Res (AACR) 2002, 43: Abst. 788.
-
-
-
-
150
-
-
43049096234
-
-
Wilex and Fox Chase Cancer Center begin clinical trial in the U.S. with novel compound WX-UK1 targeting tumor cell invasion and metastasis [news release]. Fox Chase Cancer Center; May 25, 2004. http://www.fccc.edu/news/ 2004/Wilex-Fox-Chase-05-25-04.html. Accessed February 15, 2008.
-
Wilex and Fox Chase Cancer Center begin clinical trial in the U.S. with novel compound WX-UK1 targeting tumor cell invasion and metastasis [news release]. Fox Chase Cancer Center; May 25, 2004. http://www.fccc.edu/news/ 2004/Wilex-Fox-Chase-05-25-04.html. Accessed February 15, 2008.
-
-
-
-
151
-
-
33846532951
-
Inhibition of urokinase plasminogen activator with a novel enzyme inhibitor. WXC-340, ameliorates endotoxin and surgery-accelerated growth of murine metastases
-
Killeen, S. D., Andrews, E.J., Wang, J.H. et al. Inhibition of urokinase plasminogen activator with a novel enzyme inhibitor. WXC-340, ameliorates endotoxin and surgery-accelerated growth of murine metastases. Br J Cancer 2007, 96(2): 262-8.
-
(2007)
Br J Cancer
, vol.96
, Issue.2
, pp. 262-268
-
-
Killeen, S.D.1
Andrews, E.J.2
Wang, J.H.3
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