(4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 10, 2000, Pages 5113-5118

  Sperl, Stefan ^a   Jacob, Uwe ^a   Arroyo De Prada, Nuria ^b   Stürzebecher, Jörg ^c   Wilhelm, Olaf G ^d   Bode, Wolfram ^a   Magdolen, Viktor ^b   Huber, Robert ^a   Moroder, Luis ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Institut für Biochemie   (Germany)

^d Wilex Biotechnology GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

(4 AMINOMETHYL)PHENYLGUANIDINE DERIVATIVE; GUANIDINE DERIVATIVE; PLASMINOGEN ACTIVATOR INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CRYSTAL STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SYNTHESIS; TUMOR CELL; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; GUANIDINES; HUMANS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; URINARY PLASMINOGEN ACTIVATOR;

EID: 0034624980     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.10.5113     Document Type: Article

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