Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site

Biochemistry

Volumn 37, Issue 47, 1998, Pages 16494-16505

  Ploug, Michael ^a  

^a FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AZIRINE DERIVATIVE; BENZOPHENONE; BUNGAROTOXIN; GLYCOLIPID; LIGAND; PHENYLALANINE; TRYPTOPHAN; UROKINASE; UROKINASE RECEPTOR;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; LIGAND BINDING; NONHUMAN; PHOTOAFFINITY LABELING; PHOTOLYSIS; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; AZIRINES; BENZOPHENONES; BINDING SITES; CHO CELLS; CRICETINAE; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; LEUCINE; LIGANDS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PHENYLALANINE; PHOTOAFFINITY LABELS; PLASMINOGEN ACTIVATORS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; TRYPTOPHAN; URINARY PLASMINOGEN ACTIVATOR;

EID: 0032564309     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981203r     Document Type: Article

References (41)

1. Ploug, M., Rønne, E., Behrendt, N., Jensen, A., Blasi, F., and Danø, K. (1991) J. Biol. Chem. 266, 1926-1936.
2. Evans, P. C., Elfman, F., Parangi, S., Conn, M., Cunha, G., and Shuman, M. A. (1997) Cancer Res. 57, 3594-3599.
3. Kook, Y.-H., Adamski, J., Zelent, A., and Ossowski, L. (1994) EMBO J. 13, 3983-3991.
4. Ossowski, L. (1988) J. Cell Biol. 107, 2437-2445.
5. Ossowski, L., Russo-Payne, H., and Wilson, E. L. (1991) Cancer Res. 57, 274-281.
6. Yu, W., Kim, J., and Ossowski, L. (1997) J. Cell Biol. 137, 767-770.
7. Min, H. Y., Doyle, L. V., Vitt, C. R., Zandonella, C. L., Stratton-Thomas, J. R., Shuman, M. A., and Rosenberg, S. (1996) Cancer Res. 56, 2428-2433.
8. Pedersen, H., Brünner, N., Francis, D., Østerlind, K., Rønne, E., Hansen, H. H., Danø, K., and Grøndahl-Nielsen, J. (1994) Cancer Res. 54, 4671-4675.
9. Ganesh, S., Sier, C. F., Heerding, M., Griffioen, G., Lamers, C. B., and Verspaget, H. W. (1994) Lancet 344, 401-402.
10. Duggan, C., Maguire, J., McDermott, E., O'Higgins, H., Fennelly, J. J., and Duffy, M. J. (1995) Int. J. Cancer 61, 597-600.
11. Goodson, R. J., Doyle, M. V., Kaufman, S. E., and Rosenberg, S. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 7129-7133.
12. Ploug, M., Østergård, S., Hansen, L. B. L., Holm, A., and Danø, K. (1998) Biochemistry 37, 3612-3622.
13. Ploug, M., Ellis, V., and Danø, K. (1994) Biochemistry 33, 8991-8997.
14. Ploug, M., Kjalke, M., Rrnne, E., Weidle, U., Høyer-Hansen, G., and Danø, K. (1993) J. Biol. Chem. 268, 17539-17546.
15. Ploug, M., Rahbek-Nielsen, H., Ellis, V., Roepstorff, P., and Danø, K. (1995) Biochemistry 34, 12524-12534.
16. Behrendt, N., Ploug, M., Patthy, L., Houen, G., Blasi, F., and Danø, K. (1991) J. Biol. Chem. 266, 7842-7847.
17. Barkholt, V., and Jensen, A. L. (1989) Anal. Biochem. 177, 318-322.
18. Ploug, M., Rahbek-Nielsen, H., Nielsen, P. F., Roepstorff, P., and Danø, K. (1998) J. Biol. Chem. 273, 13933-13943.
19. Weber, P. J. A., and Beck-Sickinger, A. G. (1997) J. Pept. Res. 49, 375-383.
20. Behrendt, N., Rønne, E., and Danø, K. (1996) J. Biol. Chem. 271, 22885-22894.
21. Dormán, G., and Prestwich, G. D. (1994) Biochemistry 33, 5661-5673.
22. Brunner, J. (1993) Annu. Rev. Biochem. 62, 483-514.
23. Ploug, M., and Ellis, V. (1994) FEBS Lett. 349, 163-168.
24. Magdolen, V., Rettenberger, P., Koppitz, M., Goretzki, L., Kassler, H., Weidle, U., König, B., Graeff, H., Schmitt, M., and Wilhelm, O (1996) Eur. J. Biochem. 237, 743-751.
25. Mourey, R. J., Estevez, V. A., Marecek, J. F., Barrow, R. K., Prestwich, G. D., and Snyder, S. H. (1993) Biochemistry 32, 1719-1726.
26. Gergel, J. R., McNamara, D. J., Dobrusin, E. M., Zhu, G., Saltiel, A. R., and Miller, W. T. (1994) Biochemistry 33, 14671-14678.
27. Pellicena, P., Scholten, J. D., Zimmerman, K., Creswell, M., Huang, C. C., and Miller, W. T. (1996) Biochemistry 35, 13494-13500.
28. Noel, L. S., Champion, B. R., Holley, C. L., Simmons, C. J., Morris, D. C., Payne, J. A., Lean, J. M., Chambers, T. J., Zaman, G., Lanyon, L. E., Suva, L. J., and Miller, L. R. (1998) J. Biol. Chem. 273, 3878-3883.
29. Fletcher, C. M., Harrison, R. A., Lachmann, P. J., and Neuhaus, D. (1994) Structure 2, 185-199.
30. Kieffer, B., Driscoll, P. C., Campbell, I. D., Willis, A. C., van der Merve, P. A., and Davis, S. J. (1994) Biochemistry 33, 4471-4482.
31. Dufton, M. J., and Hider, R. C. (1983) CRC Crit. Rev. Biochem. 14, 113-171.
32. Chiappinelli, V. A., and Lee, J. C. (1985) J. Biol. Chem. 260, 6182-6186.
33. Oswald, R. E., Sutcliffe, M. J., Bamburger, M., Loring, R. H., Braswell, E., and Dobson, C. M. (1991) Biochemistry 30, 4901-4909.
34. Dewan, J. C., Grant, G. A., and Sacchettini, J. C. (1994) Biochemistry 33, 13147-13154.
35. Sun, Y.-J., Wu, W.-G., Chiang, C.-M., Hsin, A.-Y., and Hsiao, C.-D. (1997) Biochemistry 36, 2403-2413.
36. Betzel, G., Lange, G., Pal, G. P., Wilson, K. S., Maelicke, A., and Sanger, W. (1991) J. Biol. Chem. 266, 21530-21536.
37. Rees, B., Bilwes, A., Samama, J. P., and Moras, D. (1990) J. Mol. Biol. 214, 281-297.
38. Roldan, A. L., Cubellis, M. V., Mascucci, M. T., Behrendt, N., Lund, L. R., Danø, K., Appella, E., and Blasi, F. (1990) EMBO J. 9, 467-474.
39. Vensel, W. H., and Tarr, G. E. (1995) in Techniques in Protein Chemistry (Crabb, J. W., Ed.) Vol. VI, pp 177-184, Academic Press Inc.
40. Hansen, A. P., Petros, A. M., Meadows, R. P., Nettesheim, D. G., Mazar, A. P., Olejniczak, E. T., Pederson, T. M., Henkin, J., and Fesik, S. (1994) Biochemistry 33, 4847-4864.
41. Sutcliffe, M. J., Dobson, C. M., and Oswald, R. E. (1992) Biochemistry 31, 2962-2970.