Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42

European Journal of Neuroscience

Volumn 27, Issue 9, 2008, Pages 2425-2432

  Qin, Wei ^a   Jia, Jianping ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid beta; Human; Insulin degrading enzyme; Presenilin; Subcellular fractionation

Indexed keywords

AMYLOID BETA 42; AMYLOID BETA PROTEIN; INSULINASE; PRESENILIN 1;

ALZHEIMER DISEASE; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME LOCALIZATION; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MEMBRANE; CYTOPLASM; DOWN-REGULATION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INSULYSIN; MUTATION; PRESENILIN-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 42549093995     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06207.x     Document Type: Article

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