p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid β in vivo

Journal of Neuroscience

Volumn 26, Issue 41, 2006, Pages 10536-10541

  Cruz, Jonathan C ^a,e   Kim, Dohoon ^a,d   Moy, Lily Y ^a,d   Dobbin, Matthew M ^a,d   Sun, Xiaoyan ^b   Bronson, Roderick T ^c   Tsai, Li Huei ^a,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Alzheimer's disease; Amyloid ; BACE1; Cdk5; Neurodegeneration; p25

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; PROTEIN P25; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; FOREBRAIN; IN VIVO STUDY; MOUSE; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AMYLOID BETA-PROTEIN; ANIMALS; CYCLIN-DEPENDENT KINASE 5; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE DEGENERATION; NEURONS; PHOSPHOTRANSFERASES;

EID: 33749826587     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3133-06.2006     Document Type: Article

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