A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain

EMBO Journal

Volumn 22, Issue 6, 2003, Pages 1273-1281

  Shih, Susan C ^a   Prag, Gali ^b   Francis, Smitha A ^a   Sutanto, Myra A ^a   Hurley, James H ^b   Hicke, Linda ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

CUE domain; Monoubiquitylation; Rsp5; Ubiquitin binding protein; Vps9

Indexed keywords

UBIQUITIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TANDEM REPEAT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CARRIER PROTEINS; CONSERVED SEQUENCE; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITINS; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 0345616428     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg140     Document Type: Article

References (34)

1. Beal, R., Deveraux, Q., Xia, G., Rechsteiner, M. and Pickart, C. (1996) Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting. Proc. Natl Acad. Sci. USA, 93, 861-866.
2. Bertolaet, B.L., Clarke, D.J., Wolff, M., Watson, M.H., Henze, M., Divita, G. and Reed, S.I. (2001) UBA domains of DNA damage-inducible proteins interact with ubiquitin. Nat. Struct. Biol., 8, 417-422.
3. Biederer, T., Volkwein, C. and Sommer, T. (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science, 278, 1806-1809.
4. Burd, C.G., Mustol, P.A., Schu, P.V. and Emr, S.D. (1996) A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol. Cell. Biol., 16, 2369-2377.
5. Chen, L., Shinde, U., Ortolan, T.G. and Madura, K. (2001) Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly. EMBO rep., 24, 24.
6. Dieckmann, T., Withers-Ward, E.S., Jarosinski, M.A., Liu, C.F., Chen, I.S. and Feigon, J. (1998) Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr. Nat. Struct. Biol., 5, 1042-1047.
7. Fang, S., Ferrone, M., Yang, C., Jensen, J.P., Tiwari, S. and Weissman, A.M. (2001) The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc. Natl Acad. Sci. USA, 98, 14422-14427.
8. Fisk, H.A. and Yaffe, M.P. (1999) A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae. J. Cell Biol., 145, 1199-1208.
9. Funakoshi, M., Sasaki, T., Nishimoto, T. and Kobayashi, H. (2002) Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome. Proc. Natl Acad. Sci. USA, 99, 745-750.
10. Gietz, R.D. and Sugino, A. (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene, 74, 527-534.
11. Hama, H., Tall, G.G. and Horazdovsky, B.F. (1999) Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. J. Biol. Chem., 274, 15284-15291.
12. Hershko, A. and Ciechanover, A. (1998) The ubiquitin system. Annu. Rev. Biochem., 67, 425-479.
13. Hicke, L. (2001) Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol., 2, 195-201.
14. Hochstrasser, M. (2000) Evolution and function of ubiquitin-like protein-conjugation systems. Nat. Cell Biol., 2, E153-E157.
15. Hofmann, K. and Bucher, P. (1996) The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway. Trends Biochem. Sci., 21, 172-173.
16. Hofmann, K. and Falquet, L. (2001) A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems. Trends Biochem. Sci., 26, 347-350.
17. James, P., Halladay, J. and Craig, E.A. (1996) Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics, 144, 1425-1436.
18. Jentsch, S. and Pyrowolakis, G. (2000) Ubiquitin and its kin: how close are the family ties? Trends Cell Biol., 10, 335-342.
19. Kahana, A. and Gottschling, D.E. (1999) DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Mol. Cell. Biol., 19, 6608-6620.
20. Klapisz, E., Sorokina, I., Lemeer, S., Pijnenburg, M., Verkleij, A.J. and van Bergen en Henegouwen, P.M. (2002) A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination. J. Biol. Chem., 277, 30746-30753.
21. Mueller, T.D. and Feigon, J. (2002) Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions. J. Mol. Biol., 319, 1243-1255.
22. Oldham, C.E., Mohney, R.P., Miller, S.L., Hanes, R.N. and O'Bryan, J.P. (2002) The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination. Curr. Biol., 12, 1112-1116.
23. Polo, S., Sigismund, S., Faretta, M., Guidi, M., Capua, M.R., Bossi, G., Chen, H., De Camilli, P. and Di Fiore, P.P. (2002) A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature, 416, 451-455.
24. Ponting, C.P. (2000) Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem. J., 351, 527-535.
25. Ponting, C.P. (2002) Novel domains and orthologues of eukaryotic transcription elongation factors. Nucleic Acids Res., 30, 3643-3652.
26. Raiborg, C., Bache, K.G., Gillooly, D.J., Madshus, I.H., Stang, E. and Stenmark, H. (2002) Hrs sorts ubiquitinated proteins into clathrincoated microdomains of early endosomes. Nat. Cell Biol., 4, 394-398.
27. Sheffield, P., Garrard, S. and Derewenda, Z. (1999) Overcoming expression and purification problems of RhoGDI using a family of 'parallel' expression vectors. Protein Expr. Purif., 15, 34-39.
28. Sherman, F. (1991) Getting started with yeast. Methods Enzymol., 194, 3-21.
29. Shih, S.C. (2002) Identification and characterization of the cis- and transacting components required for ubiquitin-dependent receptor endocytosis. PhD thesis, Northwestern University, Evanston, IL.
30. Shih, S.C., Sloper-Mould, K.E. and Hicke, L. (2000) Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J., 19, 187-198.
31. Shih, S.C., Katzmann, K.J., Schnell, J.D., Sutanto, M., Emr, S.C. and Hicke, L.H. (2002) Epsins and Vps27/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat. Cell Biol., 4, 389-393.
32. Sloper-Mould, K.E., Pickart, C.M. and Hicke, L. (2001) Distinct functional surface regions on ubiquitin. J. Biol. Chem., 276, 30483-30489.
33. Wilkinson, C.R., Seeger, M., Hartmann-Petersen, R., Stone, M., Wallace, M., Semple, C. and Gordon, C. (2001) Proteins containing the UBA domain are able to bind to multi-ubiquitin chains. Nat. Cell Biol., 3, 939-943.
34. Zoladek, T., Tobiasz, A., Vaduva, G., Boguta, M., Martin, N.C. and Hopper, A.K. (1997) MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution is identical to the ubiquitin-protein ligase gene RSP5. Genetics, 145, 595-603.