Ubiquitin signals protein trafficking via interaction with a novel ubiquitin binding domain in the membrane fusion regulator, Vps9p

Current Biology

Volumn 13, Issue 3, 2003, Pages 258-262

  Donaldson, Kathryn M ^a   Yin, Hongwei ^a   Gekakis, Nicholas ^a   Supek, Frantisek ^a   Joazeiro, Claudio A P ^a  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FUNGAL PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN; VESICULAR TRANSPORT PROTEIN; VPS9 PROTEIN, S CEREVISIAE;

AMINO ACID SEQUENCE; ARTICLE; ENDOCYTOSIS; GENETICS; MEMBRANE FUSION; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; CARRIER PROTEINS; ENDOCYTOSIS; FUNGAL PROTEINS; MEMBRANE FUSION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN; VESICULAR TRANSPORT PROTEINS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037316409     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(03)00043-5     Document Type: Article

References (25)

1. Bryant, N.J., and Stevens, T.H. (1998). Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole. Microbiol. Mol. Biol. Rev. 62, 230-247.
2. Horazdovsky, B.F., DeWald, D.B., and Emr, S.D. (1995). Protein transport to the yeast vacuole. Curr. Opin. Cell Biol. 7, 544-551.
3. Katzmann, D.J., Babst, M., and Emr, S.D. (2001). Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106, 145-155.
4. Polo, S., Sigismund, S., Faretta, M., Guidi, M., Capua, M.R., Bossi, G., Chen, H., De Camilli, P., and Di Fiore, P.P. (2002). A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature 416, 451-455.
5. Shih, S.C., Katzmann, D.J., Schnell, J.D., Sutanto, M., Emr, S.D., and Hicke, L. (2002). Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat. Cell Biol. 4, 389-393.
6. Raiborg, C., Bache, K.G., Gillooly, D.J., Madshus, I.H., Stang, E., and Stenmark, H. (2002). Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat. Cell Biol. 4, 394-398.
7. Bilodeau, P.S., Urbanowski, J.L., Winistorfer, S.C., and Piper, R.C. (2002). The Vps27pHselp complex binds ubiquitin and mediates endosomal protein sorting. Nat. Cell Biol. 4, 534-539.
8. Hama, H., Tall, G.G., and Horazdovsky, B.F. (1999). Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. J. Biol. Chem. 274, 14284-14291.
9. Burd, C.G., Mustol, P.A., Schu, P.V., and Emr, S.D. (1996). A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol. Cell Biol. 16, 2369-2377.
10. Shih, S.C., Sloper-Mould, K.E., and Hicke, L. (2000). Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J. 19, 187-198.
11. Hicke, L. (2001). Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol. 3, 195-201.
12. Piper, R.C., and Luzio, J.P. (2001). Late endosomes: sorting and partitioning in multivesicular bodies. Traffic 2, 612-621.
13. Beal, R.E., Toscano-Cantaffa, D., Young, P., Rechsteiner, M., and Pickart, C.M. (1998). The hydrophobic effect contributes to polyubiquitin chain recognition. Biochemistry 37, 2925-2934.
14. Gerrard, S.R., Bryant, N.J., and Stevens, T.H. (2000). VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment. Mol. Biol. Cell 11, 613-626.
15. Horiuchi, H., Lippe, R., McBride, H.M., Rubino, M., Woodman, P., Stenmark, H., Rybin, V., Wilm, M., Ashman, K., Mann, M., et al. (1997). A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 90, 1149-1159.
16. Ponting, C.P. (2000). Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem. J. 351, 527-535.
17. Biederer, T., Volkwein, C., and Sommer, T. (1997). Role of Cue1 p in ubiquitination and degradation at the ER surface. Science 278, 1806.
18. van Nocker, S., Sadis, S., Rubin, D.M., Glickman, M., Fu, H., Coux, O., Wefes, I., Finley, D., and Vierstra, R.D. (1996). The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover. Mol Cell. Biol. 16, 6020.
19. Buchberger, A. (2002). From UBA to UBX: new words in the ubiquitin vocabulary. Trends Cell Biol. 12, 216-221.
20. Dieckmann, T., Withers-Ward, E.S., Jarosinski, M.A., Liu, C.F., Chen, I.S., and Feigon, J. (1998). Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr. Nat. Struct. Biol. 5, 1042-1047.
21. Davis, N.G., Horecka, J.L., and Sprague, G.F.J. (1993). Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122, 53-65.
22. Shenoy, S.K., McDonald, P.H., Kohout, T.A., Lefkowitz, R.J. (2001). Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science 294, 1307-1303.
23. Barbieri, M.A., Roberts, R.L., Gumusboga, A., Highfield, H., Alvarez-Dominguez, C., Wells, A., and Stahl, P.D. (2000). Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J. Cell Biol. 151, 539-550.
24. Seachrist, J.L., Laporte, S.A., Dale, L.B., Babwah, A.V., Caron, M.G., Anborgh, P.H., and Ferguson, S.S. (2002). Rab5 association with the angiotensin II type 1A receptor promotes Rab5 GTP binding and vesicular fusion. J. Biol. Chem. 277, 679-685.
25. Volpicelli, L.A., Lah, J.J., and Levey, A.I. (2001). Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies. J. Biol. Chem. 276, 47590-47598.