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Volumn 14, Issue 14, 2000, Pages 1729-1733

Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation

Author keywords

Apoptosis; Endothelium; IKK; Knockout; NF B; NTD

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOTRANSFERASE;

EID: 0034661272     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (175)

References (28)
  • 1
    • 0030747128 scopus 로고    scopus 로고
    • NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle, P.A. and Baichwal, V.R. 1997. NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65: 111-137.
    • (1997) Adv. Immunol. , vol.65 , pp. 111-137
    • Baeuerle, P.A.1    Baichwal, V.R.2
  • 2
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle, P.A. and Henkel, T. 1994. Function and activation of NF-kappa B in the immune system. Annu. Rev. Immunol. 12: 141-179.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 3
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
    • DiDonato, J.A., Hayakawa, M., Rothwarf, D.M., Zandi, E., and Karin, M. 1997. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388: 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 5
    • 0032809906 scopus 로고    scopus 로고
    • p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor
    • Hamanoue, M., Middleton, C., Wyatt, S., Jaffray, E., Hay, R.T., and Davies, A.M. 1999. p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor. Mol. Cell. Neurosci. 14: 28-40.
    • (1999) Mol. Cell. Neurosci. , vol.14 , pp. 28-40
    • Hamanoue, M.1    Middleton, C.2    Wyatt, S.3    Jaffray, E.4    Hay, R.T.5    Davies, A.M.6
  • 7
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
    • Hu, Y., Baud, V., Delhase, M., Zhang, P., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science 284: 316-320.
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 8
    • 0033595893 scopus 로고    scopus 로고
    • How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
    • Karin, M. 1999. How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex. Oncogene 18: 6867-6874.
    • (1999) Oncogene , vol.18 , pp. 6867-6874
    • Karin, M.1
  • 10
    • 0033537739 scopus 로고    scopus 로고
    • Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
    • Li, Q., Van Antwerp, D., Mercurio, F., Lee, K.F., and Verma, I.M. 1999b. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science 284: 321-325.
    • (1999) Science , vol.284 , pp. 321-325
    • Li, Q.1    Van Antwerp, D.2    Mercurio, F.3    Lee, K.F.4    Verma, I.M.5
  • 11
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li, Z.W., Chu, W., Hu, Y., Delhase, M., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. 1999c. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J. Exp. Med. 189: 1839-1845.
    • (1999) J. Exp. Med. , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.2    Hu, Y.3    Delhase, M.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 13
    • 0033979815 scopus 로고    scopus 로고
    • Roles of nuclear factor kappaB in neuronal survival and plasticity
    • Mattson, M.P., Culmsee, C., Yu, Z., and Camandola, S. 2000. Roles of nuclear factor kappaB in neuronal survival and plasticity. J. Neurochem. 74: 443-456.
    • (2000) J. Neurochem. , vol.74 , pp. 443-456
    • Mattson, M.P.1    Culmsee, C.2    Yu, Z.3    Camandola, S.4
  • 16
    • 0028557348 scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B
    • Miyamoto, S., Maki, M., Schmitt, M.J., Hatanaka, M., and Verma, I.M. 1994. Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B. Proc. Natl. Acad. Sci. 91: 12740-12744.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 12740-12744
    • Miyamoto, S.1    Maki, M.2    Schmitt, M.J.3    Hatanaka, M.4    Verma, I.M.5
  • 17
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    • Pfeffer, K., Matsuyama, T., Kundig, T.M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P.S., Kronke, M., and Mak, T.W. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 457-467.
    • (1993) Cell , vol.73 , pp. 457-467
    • Pfeffer, K.1    Matsuyama, T.2    Kundig, T.M.3    Wakeham, A.4    Kishihara, K.5    Shahinian, A.6    Wiegmann, K.7    Ohashi, P.S.8    Kronke, M.9    Mak, T.W.10
  • 18
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterization of an IkappaB kinase
    • Regnier, C.H., Song, H.Y., Gao, X., Goeddel, D.V., Cao, Z., and Rothe, M. 1997. Identification and characterization of an IkappaB kinase. Cell 90: 373-383.
    • (1997) Cell , vol.90 , pp. 373-383
    • Regnier, C.H.1    Song, H.Y.2    Gao, X.3    Goeddel, D.V.4    Cao, Z.5    Rothe, M.6
  • 19
    • 0032541657 scopus 로고    scopus 로고
    • IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
    • Rothwarf, D.M., Zandi, E., Natoli, G., and Karin, M. 1998. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 395: 297-300.
    • (1998) Nature , vol.395 , pp. 297-300
    • Rothwarf, D.M.1    Zandi, E.2    Natoli, G.3    Karin, M.4
  • 21
    • 0029666306 scopus 로고    scopus 로고
    • NF-kappaB activity in transgenic mice: Developmental regulation and tissue specificity
    • Schmidt-Ullrich, R., Memet, S., Lilienbaum, A., Feuillard, J., Raphael, M., and Israel, A. 1996. NF-kappaB activity in transgenic mice: Developmental regulation and tissue specificity. Development 122: 2117-2128.
    • (1996) Development , vol.122 , pp. 2117-2128
    • Schmidt-Ullrich, R.1    Memet, S.2    Lilienbaum, A.3    Feuillard, J.4    Raphael, M.5    Israel, A.6
  • 23
    • 0033119952 scopus 로고    scopus 로고
    • Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
    • Tanaka, M., Fuentes, M.E., Yamaguchi, K., Durnin, M.H., Dalrymple, S.A., Hardy, K.L., and Goeddel, D.V. 1999. Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. Immunity 10: 421-429.
    • (1999) Immunity , vol.10 , pp. 421-429
    • Tanaka, M.1    Fuentes, M.E.2    Yamaguchi, K.3    Durnin, M.H.4    Dalrymple, S.A.5    Hardy, K.L.6    Goeddel, D.V.7
  • 25
    • 0030611595 scopus 로고    scopus 로고
    • IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
    • Woronicz, J.D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D.V. 1997. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 278: 866-869.
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 26
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
    • Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S.T., Weil, R., Agou, F., Kirk, H.E., Kay, R.J., and Israel, A. 1998. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93: 1231-1240.
    • (1998) Cell , vol.93 , pp. 1231-1240
    • Yamaoka, S.1    Courtois, G.2    Bessia, C.3    Whiteside, S.T.4    Weil, R.5    Agou, F.6    Kirk, H.E.7    Kay, R.J.8    Israel, A.9
  • 27
    • 17644445419 scopus 로고    scopus 로고
    • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
    • Yao, T.P., Oh, S.P., Fuchs, M., Zhou, N.D., Ch'ng, L.E., Newsome, D., Bronson, R.T., Li, E., Livingston, D.M., and Eckner, R. 1998. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 93: 361-372.
    • (1998) Cell , vol.93 , pp. 361-372
    • Yao, T.P.1    Oh, S.P.2    Fuchs, M.3    Zhou, N.D.4    Ch'ng, L.E.5    Newsome, D.6    Bronson, R.T.7    Li, E.8    Livingston, D.M.9    Eckner, R.10
  • 28
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
    • Zandi, E., Rothwarf, D.M., Delhase, M., Hayakawa, M. and Karin, M. 1997. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91: 243-252.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.