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Volumn 26, Issue 7, 2007, Pages 1831-1842

CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome

Author keywords

CUEDC2; Interaction; Progesterone receptor; Transactivation; Ubiquitination

Indexed keywords

HORMONE RECEPTOR; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEASOME; SMALL INTERFERING RNA; UBIQUITIN;

EID: 34247228197     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601602     Document Type: Article
Times cited : (73)

References (43)
  • 1
    • 0037072795 scopus 로고    scopus 로고
    • The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression
    • Abdel-Hafiz H, Takimoto GS, Tung L, Horwitz KB (2002) The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression. J Biol Chem 277: 33950-33956
    • (2002) J Biol Chem , vol.277 , pp. 33950-33956
    • Abdel-Hafiz, H.1    Takimoto, G.S.2    Tung, L.3    Horwitz, K.B.4
  • 2
  • 3
    • 0034705319 scopus 로고    scopus 로고
    • SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53
    • Buschmann T, Fuchs SY, Lee CG, Pan ZQ, Ronai Z (2000) SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. Cell 101: 753-762
    • (2000) Cell , vol.101 , pp. 753-762
    • Buschmann, T.1    Fuchs, S.Y.2    Lee, C.G.3    Pan, Z.Q.4    Ronai, Z.5
  • 4
    • 0037809267 scopus 로고    scopus 로고
    • Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1
    • Chauchereau A, Amazit L, Quesne M, Guiochon-Mantel A, Milgrom E (2003) Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1. J Biol Chem 278: 12335-12343
    • (2003) J Biol Chem , vol.278 , pp. 12335-12343
    • Chauchereau, A.1    Amazit, L.2    Quesne, M.3    Guiochon-Mantel, A.4    Milgrom, E.5
  • 5
    • 31044437051 scopus 로고    scopus 로고
    • The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site
    • Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM (2006) The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site. Proc Natl Acad Sci USA 103: 341-346
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 341-346
    • Chen, B.1    Mariano, J.2    Tsai, Y.C.3    Chan, A.H.4    Cohen, M.5    Weissman, A.M.6
  • 6
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • Clarke CL, Sutherland RL (1990) Progestin regulation of cellular proliferation. Endocr Rev Res 11: 266-301
    • (1990) Endocr Rev Res , vol.11 , pp. 266-301
    • Clarke, C.L.1    Sutherland, R.L.2
  • 7
    • 0032135131 scopus 로고    scopus 로고
    • SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation
    • Desterro JM, Rodriguez MS, Hay RT (1998) SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell 2: 233-239
    • (1998) Mol Cell , vol.2 , pp. 233-239
    • Desterro, J.M.1    Rodriguez, M.S.2    Hay, R.T.3
  • 8
    • 0037316409 scopus 로고    scopus 로고
    • Ubiquitin signals protein trafficking via interaction with a novel ubquitin binding domain in the membrane fusion regulator, Vps9p
    • Donalcison KM, Yin H, Gekakis N, Supek F, Hoazeiro CA (2003) Ubiquitin signals protein trafficking via interaction with a novel ubquitin binding domain in the membrane fusion regulator, Vps9p. Curr Biol 13: 258-262
    • (2003) Curr Biol , vol.13 , pp. 258-262
    • Donalcison, K.M.1    Yin, H.2    Gekakis, N.3    Supek, F.4    Hoazeiro, C.A.5
  • 11
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor super-family
    • Evans R (1988) The steroid and thyroid hormone receptor super-family. Science 240: 889-895
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.1
  • 12
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG (2000) The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14: 121-141
    • (2000) Genes Dev , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 13
    • 0036720691 scopus 로고    scopus 로고
    • c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription
    • Goh ELK, Zhu T, Leong WY, Lobie PE (2002) c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription. Endocrinology 148: 3590-3603
    • (2002) Endocrinology , vol.148 , pp. 3590-3603
    • Goh, E.L.K.1    Zhu, T.2    Leong, W.Y.3    Lobie, P.E.4
  • 15
    • 0023212905 scopus 로고
    • Progestin effects on growth in the human breast cancer cell line T-47D-possible therapeutic implications
    • Hissom JR, Moore MR (1987) Progestin effects on growth in the human breast cancer cell line T-47D-possible therapeutic implications. Biochem Biophys Res Commun 145: 706-711
    • (1987) Biochem Biophys Res Commun , vol.145 , pp. 706-711
    • Hissom, J.R.1    Moore, M.R.2
  • 16
    • 0021070493 scopus 로고
    • In situ photolinked nuclear progesterone receptors of human breast cancer cells: Subunit molecular weights after transformation and translocation
    • Horwitz K, Alexander P (1983) In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation. Endocrinology 113: 2195-2201
    • (1983) Endocrinology , vol.113 , pp. 2195-2201
    • Horwitz, K.1    Alexander, P.2
  • 17
    • 0016750072 scopus 로고
    • Specific progesterone receptors in human breast cancer
    • Horwitz KB, McGuire WL (1975) Specific progesterone receptors in human breast cancer. Steroids 25: 497-505
    • (1975) Steroids , vol.25 , pp. 497-505
    • Horwitz, K.B.1    McGuire, W.L.2
  • 18
    • 0032566365 scopus 로고    scopus 로고
    • Coactivators and corepressors as mediators of nuclear receptor function: An update
    • Jenster G (1998) Coactivators and corepressors as mediators of nuclear receptor function: an update. Mol Cell Biol 143: 1-7
    • (1998) Mol Cell Biol , vol.143 , pp. 1-7
    • Jenster, G.1
  • 19
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P (1990) Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 9: 1603-1614
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 20
    • 0033305372 scopus 로고    scopus 로고
    • Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals
    • Lange CA, Richer JK, Horwitz KB (1999) Hypothesis: progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals. Mol Endocrinol 13: 829-836
    • (1999) Mol Endocrinol , vol.13 , pp. 829-836
    • Lange, C.A.1    Richer, J.K.2    Horwitz, K.B.3
  • 21
    • 0033967491 scopus 로고    scopus 로고
    • Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome
    • Lange CA, Shen T, Horwitz KB (2000) Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. Proc Natl Acad Sci USA 97: 1032-1037
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1032-1037
    • Lange, C.A.1    Shen, T.2    Horwitz, K.B.3
  • 22
    • 0034615669 scopus 로고    scopus 로고
    • The SRC family of nuclear receptor coactivators
    • Leo C, Chen JD (2000) The SRC family of nuclear receptor coactivators. Gene (Amst) 245: 1-11
    • (2000) Gene (Amst) , vol.245 , pp. 1-11
    • Leo, C.1    Chen, J.D.2
  • 23
    • 0033601124 scopus 로고    scopus 로고
    • Repression: Targeting the heart of the matter
    • Maldonado E, Hampsey M, Reinberg D (1999) Repression: targeting the heart of the matter. Cell 99: 455-458
    • (1999) Cell , vol.99 , pp. 455-458
    • Maldonado, E.1    Hampsey, M.2    Reinberg, D.3
  • 27
    • 0026051580 scopus 로고
    • Progestin both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor α, epidermal growth factor receptor, c-fos, and c-myc genes
    • Musgrove EA, Lee CS, Sutherand RL (1991) Progestin both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor α, epidermal growth factor receptor, c-fos, and c-myc genes. Mol Cell Biol 11: 5032-5043
    • (1991) Mol Cell Biol , vol.11 , pp. 5032-5043
    • Musgrove, E.A.1    Lee, C.S.2    Sutherand, R.L.3
  • 28
    • 0030995982 scopus 로고    scopus 로고
    • Estradiol up regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells
    • Nancy HI, Tornesi MB (1997) Estradiol up regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells. Biol Reprod 56: 1205-1215
    • (1997) Biol Reprod , vol.56 , pp. 1205-1215
    • Nancy, H.I.1    Tornesi, M.B.2
  • 30
    • 0034667598 scopus 로고    scopus 로고
    • Proteins of the endoplasmic-retivulum-associated degradation pathway: Domain detection and function prediction
    • Ponting CP (2000) Proteins of the endoplasmic-retivulum-associated degradation pathway: domain detection and function prediction. Biochem J 351: 527-535
    • (2000) Biochem J , vol.351 , pp. 527-535
    • Ponting, C.P.1
  • 31
    • 0037085303 scopus 로고    scopus 로고
    • Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells
    • Richer J, Jacobsen B, Manning N, Abel M,Wolf D, Horwitz K (2002) Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells. J Biol Chem 277: 5209-5218
    • (2002) J Biol Chem , vol.277 , pp. 5209-5218
    • Richer, J.1    Jacobsen, B.2    Manning, N.3    Abel, M.4    Wolf, D.5    Horwitz, K.6
  • 32
    • 0028026693 scopus 로고
    • New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: Only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP
    • Sartorius C, Groshong S, Miller L, Powell R, Tung L, Takimoto G, Horwitz K (1994a) New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res 54: 3868-3877
    • (1994) Cancer Res , vol.54 , pp. 3868-3877
    • Sartorius, C.1    Groshong, S.2    Miller, L.3    Powell, R.4    Tung, L.5    Takimoto, G.6    Horwitz, K.7
  • 33
    • 0028073682 scopus 로고
    • A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform
    • Sartorius C, Melville M, Hovland A, Tung L, Takimoto G, Horwitz K (1994b) A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Mol Endocrinol 8: 1347-1360
    • (1994) Mol Endocrinol , vol.8 , pp. 1347-1360
    • Sartorius, C.1    Melville, M.2    Hovland, A.3    Tung, L.4    Takimoto, G.5    Horwitz, K.6
  • 34
    • 0035726623 scopus 로고    scopus 로고
    • Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294
    • Shen T, Horwitz KB, Lange CA (2001) Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. Mol Cell Biol 21: 6122-6131
    • (2001) Mol Cell Biol , vol.21 , pp. 6122-6131
    • Shen, T.1    Horwitz, K.B.2    Lange, C.A.3
  • 35
    • 0345616428 scopus 로고    scopus 로고
    • A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain
    • Shih SC, Prag G, Francis SA, Sutanto MA, Hurley JH, Hicke L (2003) A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J 22: 1273-1281
    • (2003) EMBO J , vol.22 , pp. 1273-1281
    • Shih, S.C.1    Prag, G.2    Francis, S.A.3    Sutanto, M.A.4    Hurley, J.H.5    Hicke, L.6
  • 36
    • 0031240307 scopus 로고    scopus 로고
    • A specific role for cyclin D1 in mammary gland development
    • Sicinski P, Weinberg RA (1997) A specific role for cyclin D1 in mammary gland development. J Mammary Gland Biol Neoplasia 2: 335-342
    • (1997) J Mammary Gland Biol Neoplasia , vol.2 , pp. 335-342
    • Sicinski, P.1    Weinberg, R.A.2
  • 37
    • 13544276888 scopus 로고    scopus 로고
    • Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases
    • Skildum A, Faivre E, Lange CA (2005) Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases. Mol Endocrinol 19: 327-339
    • (2005) Mol Endocrinol , vol.19 , pp. 327-339
    • Skildum, A.1    Faivre, E.2    Lange, C.A.3
  • 39
    • 0027494065 scopus 로고
    • Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors
    • Tung L, Mohamed M, Hoeffler J, Takimoto G, Horwitz K (1993) Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors. Mol Endocrinol 7: 1256-1265
    • (1993) Mol Endocrinol , vol.7 , pp. 1256-1265
    • Tung, L.1    Mohamed, M.2    Hoeffler, J.3    Takimoto, G.4    Horwitz, K.5
  • 40
    • 0031910827 scopus 로고    scopus 로고
    • The nuclear corepressors NcoR and SMRTare key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor
    • Wagner BL, Norris JD, Knotts TA, Weigel NL, McDonnell DP (1998) The nuclear corepressors NcoR and SMRTare key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor. Mol Cell Biol 18: 1369-1378
    • (1998) Mol Cell Biol , vol.18 , pp. 1369-1378
    • Wagner, B.L.1    Norris, J.D.2    Knotts, T.A.3    Weigel, N.L.4    McDonnell, D.P.5
  • 42
    • 0029855010 scopus 로고    scopus 로고
    • Steroid hormone receptors and their regulation by phosphorylation
    • Weigel NL (1996) Steroid hormone receptors and their regulation by phosphorylation. Biochem J 319: 657-667
    • (1996) Biochem J , vol.319 , pp. 657-667
    • Weigel, N.L.1
  • 43
    • 0030923066 scopus 로고    scopus 로고
    • Zhang YX, Beck CA, Poletti A, Clement IV JP, Prendergast P, Yip TT, Hutchens TW, Edwards DP, Weigel NL (1997) Phosphorylation of human progesterone receptor by cyclin-dependent kinase 2 on three sites that are authentic basal phosphorylation sites in vivo. Mol Endocrinol 11: 823-832
    • Zhang YX, Beck CA, Poletti A, Clement IV JP, Prendergast P, Yip TT, Hutchens TW, Edwards DP, Weigel NL (1997) Phosphorylation of human progesterone receptor by cyclin-dependent kinase 2 on three sites that are authentic basal phosphorylation sites in vivo. Mol Endocrinol 11: 823-832


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