Effect of house dust mite immunotherapy on transforming growth factor β1-producing T cells in asthmatic children

Annals of Allergy, Asthma and Immunology

Volumn 100, Issue 4, 2008, Pages 314-322

  Ajduk, Jakov ^a   Marinic, Igor ^a   Aberle, Neda ^b   Rabatic, Sabina ^a   Gagro, Alenka ^a  

^a INSTITUTE OF IMMUNOLOGY   (Croatia)

^b DR JOSIP BEN EVI GENERAL HOSPITAL   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RO ANTIGEN; CD69 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FLUTICASONE PROPIONATE; IMMUNOGLOBULIN E; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ASTHMA; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CHILD; CONTROLLED STUDY; DERMATOPHAGOIDES; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; MALE; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

EID: 42049094601     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60592-3     Document Type: Article

References (42)

1. Janeway CA, Travers P, Walport M, Shlomchik MJ, eds. Immunobiology: The Immune System in Health and Disease. 6th ed. New York, NY: Garland Science Publishing; 2005.
2. Francis JN, Larche M. Peptide-based vaccination: where do we stand? Curr Opin Allergy Clin Immunol. 2005;5:537-543.
3. Curtis HH. The immunizing cure for hay fever. N Y Med J. 1900;77:16-19.
4. Van Ree R, Van Leeuwen WA, Dieges PH, et al. Measurement of IgE antibodies against purified grass pollen allergens (Lol p1, 2, 3 and 5) during immunotherapy. Clin Exp Allergy. 1997;27:68-74.
5. Devey ME, Wilson DV, Wheeler AW. The IgG subclasses of antibodies to grass pollen allergens produced in hay fever patients during hyposensitization. Clin Allergy. 1976;6:227-236.
6. Akdis CA, Blesken T, Akdis M, Wuthrich B, Blaser K. Role of interleukin 10 in specific immunotherapy. J Clin Invest. 1998;102:98-106.
7. McHugh RS, Shevach EM. The role of suppressor T cells in regulation of immune responses. J Allergy Clin Immunol. 2002;110:693-702.
8. Weiner HL. Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells. Immunol Rev. 2001;182:207-214.
9. Roncarolo MG, Bacchetta R, Bordignon C, Narula S, Levings MK. Type 1 T regulatory cells. Immunol Rev. 2001;182:68-79.
10. Wilson SB, Delovitch TL. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat Rev Immunol. 2003;3:211-222.
11. Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+) CD25(+) T cells with regulatory properties from human blood. J Exp Med. 2001;193:1303-1310.
12. Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4(+) CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med. 2001;193:1285-1294.
13. Taams LS, Smith J, Rustin MH, Salmon M, Poulter LW, Akbar AN. Human anergic/suppressive CD4(+) CD25(+) T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol. 2001;31:1122-1131.
14. high regulatory cells in human peripheral blood. J Immunol. 2001;167:1245-1253.
15. + immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12:431-440.
16. + regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev. 2001;182:18-32.
17. + suppressor T cells. Immunol Rev. 2001;182:58-67.
18. Jutel M, Akdis M, Budak F, et al. IL-10 and TGF-β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol. 2003;33:1205-1214.
19. Roberts G, Hurley C, Turcanu V, Lack G. Grass pollen immunotherapy as an effective therapy for childhood seasonal allergic asthma. J Allergy Clin Immunol. 2006;117:263-268.
20. Trescec A, Kolevska T, Cvoriscec B, et al. Characterization and partial purification of the Croatian national standard Dermatophagoides pteronyssinus allergen extract. Allergy. 1993;48:454-459.
21. Bendelja K, Gagro A, Baće A, et al. Predominant type-2 response in infants with respiratory syncytial virus (RSV) infection demonstrated by cytokine flow cytometry. Clin Exp Immunol. 2000;121:332-338.
22. DiSanto JP, Klein JS, Flomenberg N. Phosphorylation and downregulation of CD4 and CD8 in human CTLs and mouse L cells. Immunogenics. 1989;30:494-501.
23. + regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med. 2004;199:1679-1688.
24. Rolinck-Werninghaus C, Kopp M, Liebke C, Lange J, Wahn U, Niggemann B. Lack of detectable alterations in immune responses during sublingual immunotherapy in children with seasonal allergic rhinoconjunctivitis to grass pollen. Int Arch Allergy Immunol. 2005;136:134-141.
25. + T lymphocytes in peripheral blood from patients with atopic asthma. Clin Immunol. 2004;113:172-178.
26. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2000;192:303-310.
27. + T helper type 1 cells to sites of allergen-induced late-phase skin reactions in cat-allergic subjects. Clin Exp Allergy. 2005;35:52-58.
28. Alenmyr L, Matheu V, Uller L, et al. Blockade of CTLA-4 promotes airway inflammation in naive mice exposed to aerosolized allergen but fails to prevent inhalation tolerance. Scand J Immunol. 2005;62:437-444.
29. Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-1061.
30. + T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur J Immunol. 2002;32:1282-1291.
31. + precursors. J Immunol. 2005;175:6107-6116.
32. + regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A. 2004;101:4572-4577.
33. + T cells: a double-blind placebo-controlled study. Allergy. 2004;59:1097-1101.
34. Schmidt-Weber CB, Blaser K. The role of TGF-β in allergic inflammation. Immunol Allergy Clin North Am. 2006;26:233-244.
35. + T cells by grass pollen immunotherapy. J Allergy Clin Immunol. 2003;111:1255-1261.
36. Hawrylowicz CM, O'Garra A. Potential role of interleukin-10 secreting regulatory T cells in allergy and asthma. Nat Rev Immunol. 2005;5:271-283.
37. Richter A, Lohning M, Radbruch A. Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression. J Exp Med. 1999;190:1439-1450.
38. Mamessier E, Birnbaum J, Dupuy P, Vervloet D, Magnan A. Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy. Clin Exp Allergy. 2006;36:704-713.
39. Pajno GB, Morabito L, Barberio G, Parmiani S. Clinical and immunologic effects of long-term sublingual immunotherapy in asthmatic children sensitized to mites: a double-blind, placebo-controlled study. Allergy. 2000;55:842-849.
40. Bousquet J, Hejjaoui A, Clauzel AM, et al. Specific immunotherapy with a standardized Dermatophagoides pteronyssinus extract, II: prediction of efficacy of immunotherapy. J Allergy Clin Immunol. 1988;82:971-977.
41. Peek EJ, Richards DF, Faith A, et al. Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and β2-agonists. Am J Respir Cell Mol Biol. 2005;33:105-111.
42. Karagiannidis C, Akdis M, Holopainen P, et al. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol. 2004;114:1425-1433.