Ambient glucose levels qualify the potency of insulin myogenic actions by regulating SIRT1 and FoxO3a in C2C12 myocytes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 294, Issue 4, 2008, Pages

  Nedachi, Taku ^a   Kadotani, Akito ^a,c   Ariga, Miyako ^a,b   Katagiri, Hideki ^b,c   Kanzaki, Makoto ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Lab of Molec and Biochem Toxicol Grad Sch Pharmaceutical Sci T   (Japan)

^c Division of CJD Science and Technology   (Japan)

Author keywords

Differentiation; Forkhead box O

Indexed keywords

ENZYME INHIBITOR; GLUCOSE; INSULIN; SIRTINOL; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLUCOSE METABOLISM; HORMONAL REGULATION; INSULIN RESPONSE; INSULIN SENSITIVITY; MOUSE; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD PROTEINS; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; DRUG SYNERGISM; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; MICE; MUSCLE FIBERS; MUSCLE, SKELETAL; MYOBLASTS; PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIRTUINS;

EID: 41649102028     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00640.2007     Document Type: Article

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