Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: Dominant negative p85 expression blocks differentiation of L6E9 muscle cells

Molecular Endocrinology

Volumn 12, Issue 1, 1998, Pages 66-77

  Kaliman, Perla ^a   Canicio, Judith ^a   Shepherd, Peter R ^b   Beeton, Carolyn A ^b   Testar, Xavier ^a   Palacín, Manuel ^a   Zorzano, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL FUSION; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBUNIT; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORT; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SIZE; CHROMONES; GLUCOSE TRANSPORTER TYPE 4; ISOENZYMES; MICROTUBULES; MONOSACCHARIDE TRANSPORT PROTEINS; MORPHOLINES; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOGENIN; RATS; SIGNAL TRANSDUCTION; SOMATOMEDINS;

ANIMALIA;

EID: 0031917412     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.12.1.66     Document Type: Article

References (54)

1. Florini JR, Ewton DZ, Magri KA 1991 Hormones, growth factors and myogenic differentiation. Annu Rev Physiol 53:201-216
2. Edwall D, Schalling M, Jennische E, Norstedt G 1989 Induction of insulin-like growth factor I messenger ribonucleic acid during regeneration of rat skeletal muscle. Endocrinology 124:820-825
3. Jennische E, Olivecrona H 1987 Transient expression of IGF-I immunoreactivity in skeletal muscle cells during postnatal developement in the rat. Acta Physiol Scand 131:619-622
4. Tollefsen S, Lajara R, McCusker RH, Clemmons DR, Rotwein P 1989 Insulin-like growth factors in muscle development. J Biol Chem 264:13810-13817
5. Tollefsen S, Levis Sadow J, Rotwein P 1989 Coordinate expression of insulin-like growth factor-II and its receptor during muscle differentiation. Proc Natl Acad Sci USA 86:1543-1547
6. Florini JR, Magri KA, Ewton DZ, James PL, Grindstaff K, Rotwein PS 1991 "Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II. J Biol Chem 266:15917-15923
7. Rosen KM, Wentworth BM, Rosenthal N, Villa-Komaroff L 1993 Specific, temporally regulated expression of the insulin-like growth factor-II gene during muscle cell differentiation. Endocrinology 133:474-481
8. Kou Kou, Rotwein PS 1993 Transcriptional activation of the insulin-like growth factor-II gene during myoblast differentiation. Mol Endocrinol 7:291-302
9. Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:73-82
10. Powell-Braxton L, Hollingshead P, Warburton C, Dowd M, Pitts-Meek S, Dalton D, Gillett N, Stewart TA 1993 IGF-I is required for normal embyonic growth in mice. Genes Dev 7:2609-2617
11. Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ 1995 Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem 270:12109-12116
12. Reiss K, Cheng W, Ferber A, Kajstura J, Li P, Baosheng L, Olivetti G, Homcy CJ, Baserga R, Anversa P 1996 Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci USA 93:8630-8635
13. Florini JR, Ewton DZ, Coolican SA 1996 Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 17:481-517
14. Kaliman P, Viñals F, Testar X, Palacín M, Zorzano A 1996 Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells. J Biol Chem 271:19146-19151
15. Coolican SA, Samuel DS, Ewton DZ, McWade FJ, Florini JR 1997 The mitogenic and myogenic actions of IGFs utilize distinct signaling pathways. J Biol Chem 272:6653-6662
16. Ui M, Okada T, Hazeki K, Hazeki O 1995 Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 20:303-307
17. Vlahos CJ, Matter WF, Hui KY, Brown RF 1994 A specific inhibitor of phosphatidylinositol 3-kinase and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248
18. Cross MJ, Stewart A, Hodgkin MN, Kerr DJ, Wakelam MJO 1995 Wortmannin and its structural analog demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 270:25352-25355
19. Meyers R, Cantley LC 1997 Cloning and characterization of a wortmannin-sensitive phosphatidylinositol 4-kinase. J Biol Chem 272:4384-4390
20. Bonser RW, Thompson NT, Randall RW, Tateson JE, Spacey GD, Hodson HF, Garland LG 1991 Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil. Br J Pharmacol 103:1237-1241
21. Arcaro A, Wymann MP 1993 Wortmannin is a potent PI 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses. Biochem J 296: 297-301
22. James DE, Strube M, Mueckler M 1989 Molecular cloning and characterization of an insulin-regulatable glucose transporter. Nature 338:83-87
23. Shepherd PR, Navé BT, Rincon J, Nolte LA, Bevan AP, Siddle K, Zierath JR, Wallberg-Kenriksson H 1997 Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle. J Biol Chem 272:19000-19007
24. Hara K, Yonezawa K, Sakaue H, Ando A, Kotani K, Kitamura T, Kitamura Y, Ueda H, Stephens L, Jackson TR, Hawkins P, Dhand R, Clark AE, Holman GD, Waterfield MD, Kasuga M 1994 1-PI3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc Natl Acad Sci USA 91: 7415-7419
25. Kaliman P, Viñals F, Testar X, Palacín M, Zorzano A 1995 Disruption of GLUT1 glucose carrier trafficking in L6E9 and Sol8 myoblasts by the phosphatidylinositol 3-kinase inhibitor wortmannin. Biochem J 312:471-477
26. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M 1994 Essential role of PI3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J Biol Chem 269: 3568-3573
27. Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD 1994 Inhibition of translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the PI3-kinase inhibitor, wortmannin. Biochem J 300:631-635
28. Shimizu Y, Shimazu T 1994 Effects of wortmannin on increased glucose transport by insulin and norepinephrine in primary culture of brown adipocytes. Biochem Biophys Res Commun 202:660-665
29. Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kah CR 1994 PI3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
30. Sanchez-Margálet V, Goldfine ID, Vlahos CJ, Sung CK 1994 Role of PI3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochem Biophys Res Commun 204:446-452
31. Beguinot F, Kahn CR, Moses AC, Smith RJ 1985 Distinct biologically active receptors for insulin, insulin growth factor I and insulin-like growth factor-II in cultured skeletal muscle cells. J Biol Chem 260:15892-15898
32. Kimura K, Hattori S, Kabuyama Y, Shizawa Y, Takayanagi J, Nakamura S, Toki S, Matsuda Y, Onodera K, Fukui Y 1994 Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 269:18961-18967
33. Rosenthal SM, Hsiao D, Silverman LA 1994 An insulin-like growth factor-II (IGF-II) analog with highly selective affinity for IGF-II receptors stimulates differentiation, but not IGF-I receptor down-regulation in muscle cells. Endocrinology 135:38-44
34. Vanhaesebroeck B, Stein RC, Waterfield MD 1996 The study of phosphoinositide 3-kinase function. Cancer Surv 27:249-270
35. Otsu M, Hiles I, Gout I, Fry MJ, Ruiz-Larrea F, Panayotou G, Thompson A, Dhand R, Hsuan J, Totty N, Smith AD, Morgan SJ, Courtneidge SA, Parker PJ, Waterfield MD 1991 Characterization of two 85 kDa proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI 3-kinase. Cell 65:91-104
36. Escobedo JA, Navankasattusas S, Kavanaugh WM, Milfay D, Fried VA, Williams LT 1991 cDNA cloning of a novel 85 kd protein that has SH2 domains and regulated binding of PI3-kinase to the PDGF β-receptor. Cell 65:75-82
37. Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schelessinger J 1991 Cloning of PI3 kinase associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell 65:83-90
38. Pons S, Asano T, Glasheen E, Miralpeix M, Zhang Y, Fisher TL, Myers MG, Sun XJ, White MF 1995 The structure and function of p55 PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase. Mol Cell Biol 15:4453-4465
39. Antonetti DA, Algenstaedt P, Kahn CR 1996 Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol Cell Biol 16:2195-2203
40. Hiles ID, Otsu M, Volinia S, Fry MJ, Gout I, Dhand R, Panayotou G, Ruiz-Larrea F, Thompson A, Totty NF, Hsuan J, Courtneidge SA, Parker PJ, Waterfield MD 1992 Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 70:419-429
41. Hu P, Mondino A, Skolnik EY, Schelesinger J 1993 Cloning of a novel and ubiquitously expressed human PI3-kinase and identification of its binding site on p85. Mol Cell Biol 13:7677-7688
42. Dhand R, Hiles I, Panayotou G, Roche S, Fry MJ, Gout I, Totty NF, Truong O, Vicendo P, Yonezawa K, Kasuga M, Courtneidge SA, Waterfield MD 1994 PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J 13:522-533
43. Lam K, Carpenter CL, Ruderman NB, Friel JC, Kelly KL 1994 PI3-kinase phosphorylates IRS-I. Stimulation by insulin and inhibition by wortmannin. J Biol Chem 269:20648-20652
44. Tanti J-F, Grémaux T, Van Obberghen E, Le Marchand-Brustel Y 1994 Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase. Biochem J 304:17-21
45. Cross DAE, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA 1995 Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789
46. 3. J Biol Chem 269:32358-32367
47. Nakanishi H, Brewer KA, Exton JH 1993 Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-triphosphate. J Biol Chem 268:13-16
48. Ettinger SL, Lauener RW, Duronio V 1996 Protein kinase δ specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. J Biol Chem 271:14514-14518
49. Lechner C, Zahalka MA, Giot J-F, Moller NP, Ullrich A 1996 ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation Proc Natl Acad Sci USA 93:4355-4359
50. Castelló A, Rodríguez-Manzaneque JC, Camps M, Pérez-Castillo A, Testar X, Palacin M, Santos A, Zorzano A 1994 Perinatal hypothyroidism impairs the normal transition of GLUT4 and GLUT1 glucose transporters from fetal to neonatal levels in heart and brown adipose tissue. Evidence for tissue-specific regulation of GLUT4 expression by thyroid hormone. J Biol Chem 269:5905-5912
51. Pujades C, Forsberg E, Enrich C, Johansson S 1992 Changes in cell surface expression of fibronectin and fibronectin receptor during liver regeneration. J Cell Sci 102:815-820
52. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:136-159
53. Rosen KM, Villa-Komaroff L 1990 An alternative method for the visualization of RNA in formaldehyde agarose gels. Focus (Idaho) 12:23-24
54. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685