-
1
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006;355:2408-2417.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
-
2
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib. N Engl J Med. 2004;350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
3
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
4
-
-
33845914783
-
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomised controlled trial
-
Smith I, Procter M, Gelber RD, et al. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet. 2007;369:29-36.
-
(2007)
Lancet
, vol.369
, pp. 29-36
-
-
Smith, I.1
Procter, M.2
Gelber, R.D.3
-
5
-
-
22044442973
-
Tyrosine kinases as targets for cancer therapy
-
Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med. 2005;353:172-187.
-
(2005)
N Engl J Med
, vol.353
, pp. 172-187
-
-
Krause, D.S.1
Van Etten, R.A.2
-
6
-
-
0035203382
-
Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts
-
Birkenkamp KU, Geugien M, Lemmink HH, Kruijer W, Vellenga E. Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts. Leukemia. 2001;15:1923-1931.
-
(2001)
Leukemia
, vol.15
, pp. 1923-1931
-
-
Birkenkamp, K.U.1
Geugien, M.2
Lemmink, H.H.3
Kruijer, W.4
Vellenga, E.5
-
7
-
-
0031803213
-
Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia
-
Hayakawa F, Towatari M, Iida H, et al. Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. Br J Haematol. 1998;101:521-528.
-
(1998)
Br J Haematol
, vol.101
, pp. 521-528
-
-
Hayakawa, F.1
Towatari, M.2
Iida, H.3
-
8
-
-
0036190076
-
Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells
-
Spiekermann K, Pau M, Schwab R, Schmieja K, Franzrahe S, Hiddemann W. Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells. Exp Hematol. 2002;30:262-271.
-
(2002)
Exp Hematol
, vol.30
, pp. 262-271
-
-
Spiekermann, K.1
Pau, M.2
Schwab, R.3
Schmieja, K.4
Franzrahe, S.5
Hiddemann, W.6
-
9
-
-
31544474025
-
Rare occurrence of the JAK2 V617F mutation in AML subtypes M5, M6, and M7
-
Fröhling S, Lipka DB, Kayser S, et al. Rare occurrence of the JAK2 V617F mutation in AML subtypes M5, M6, and M7. Blood. 2006;107:1242-1243.
-
(2006)
Blood
, vol.107
, pp. 1242-1243
-
-
Fröhling, S.1
Lipka, D.B.2
Kayser, S.3
-
10
-
-
0028224348
-
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
-
Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell. 1994;77:307-316.
-
(1994)
Cell
, vol.77
, pp. 307-316
-
-
Golub, T.R.1
Barker, G.F.2
Lovett, M.3
Gilliland, D.G.4
-
11
-
-
33846926552
-
Tyrosine kinase mutations of JAK2 are rare events in AML but influence prognosis of patients with CBF-leukemias
-
Illmer T, Schaich M, Ehninger G, Thiede C. Tyrosine kinase mutations of JAK2 are rare events in AML but influence prognosis of patients with CBF-leukemias. Haematologica. 2007;92:137-138.
-
(2007)
Haematologica
, vol.92
, pp. 137-138
-
-
Illmer, T.1
Schaich, M.2
Ehninger, G.3
Thiede, C.4
-
12
-
-
25844447519
-
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia
-
Jelinek J, Oki Y, Gharibyan V, et al. JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia. Blood. 2005;106:3370-3373.
-
(2005)
Blood
, vol.106
, pp. 3370-3373
-
-
Jelinek, J.1
Oki, Y.2
Gharibyan, V.3
-
13
-
-
33644752653
-
The JAK2 V617F mutation in de novo acute myelogenous leukemias
-
Lee JW, Kim YG, Soung YH, et al. The JAK2 V617F mutation in de novo acute myelogenous leukemias. Oncogene. 2006;25:1434-1436.
-
(2006)
Oncogene
, vol.25
, pp. 1434-1436
-
-
Lee, J.W.1
Kim, Y.G.2
Soung, Y.H.3
-
14
-
-
25844518265
-
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
-
Levine RL, Loriaux M, Huntly BJ, et al. The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia. Blood. 2005;106:3377-3379.
-
(2005)
Blood
, vol.106
, pp. 3377-3379
-
-
Levine, R.L.1
Loriaux, M.2
Huntly, B.J.3
-
15
-
-
0141465061
-
The role of FLT3 in haematopoietic malignancies
-
Stirewalt DL, Radich JP. The role of FLT3 in haematopoietic malignancies. Nat Rev Cancer. 2003;3:650-665.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 650-665
-
-
Stirewalt, D.L.1
Radich, J.P.2
-
16
-
-
0033820091
-
Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation
-
Tse KF, Mukherjee G, Small D. Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation. Leukemia. 2000;14:1766-1776.
-
(2000)
Leukemia
, vol.14
, pp. 1766-1776
-
-
Tse, K.F.1
Mukherjee, G.2
Small, D.3
-
17
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters DK, Mercher T, Gu TL, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10:65-75.
-
(2006)
Cancer Cell
, vol.10
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
-
18
-
-
0035871889
-
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
-
Yamamoto Y, Kiyoi H, Nakano Y, et al. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood. 2001;97:2434-2439.
-
(2001)
Blood
, vol.97
, pp. 2434-2439
-
-
Yamamoto, Y.1
Kiyoi, H.2
Nakano, Y.3
-
19
-
-
16944365287
-
Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
-
Yokota S, Kiyoi H, Nakao M, et al. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines. Leukemia. 1997;11:1605-1609.
-
(1997)
Leukemia
, vol.11
, pp. 1605-1609
-
-
Yokota, S.1
Kiyoi, H.2
Nakao, M.3
-
20
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C, Stephens P, Smith R, et al. Patterns of somatic mutation in human cancer genomes. Nature. 2007;446:153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
-
21
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjöblom T, Jones S, Wood LD, et al. The consensus coding sequences of human breast and colorectal cancers. Science. 2006;314:268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
-
22
-
-
33745717815
-
Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes
-
Walters DK, Goss VL, Stoffregen EP, et al. Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes. Leuk Res. 2006;30:1097-1104.
-
(2006)
Leuk Res
, vol.30
, pp. 1097-1104
-
-
Walters, D.K.1
Goss, V.L.2
Stoffregen, E.P.3
-
23
-
-
34347384179
-
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia
-
Gu TL, Mercher T, Tyner JW, et al. A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Blood. 2007;110:323-333.
-
(2007)
Blood
, vol.110
, pp. 323-333
-
-
Gu, T.L.1
Mercher, T.2
Tyner, J.W.3
-
24
-
-
33845501610
-
Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
-
Gu TL, Goss VL, Reeves C, et al. Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. Blood. 2006;108:4202-4204.
-
(2006)
Blood
, vol.108
, pp. 4202-4204
-
-
Gu, T.L.1
Goss, V.L.2
Reeves, C.3
-
25
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
26
-
-
4644336023
-
Revealing the world of RNA interference
-
Mello CC, Conte D, Jr. Revealing the world of RNA interference. Nature. 2004;431:338-342.
-
(2004)
Nature
, vol.431
, pp. 338-342
-
-
Mello, C.C.1
Conte Jr., D.2
-
27
-
-
33646343474
-
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
-
Brummelkamp TR, Fabius AW, Mullenders J, et al. An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors. Nat Chem Biol. 2006;2:202-206.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 202-206
-
-
Brummelkamp, T.R.1
Fabius, A.W.2
Mullenders, J.3
-
28
-
-
20444426889
-
A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity
-
Kolfschoten IG, van Leeuwen B, Berns K, et al. A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell. 2005;121:849-858.
-
(2005)
Cell
, vol.121
, pp. 849-858
-
-
Kolfschoten, I.G.1
van Leeuwen, B.2
Berns, K.3
-
29
-
-
33645217264
-
Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway
-
Korherr C, Gille H, Schafer R, et al. Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway. Proc Natl Acad Sci U S A. 2006;103:4240-4245.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4240-4245
-
-
Korherr, C.1
Gille, H.2
Schafer, R.3
-
30
-
-
0037470952
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum L, Yao S, Mozer B, et al. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science. 2003;299:2039-2045.
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
Yao, S.2
Mozer, B.3
-
31
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
MacKeigan JP, Murphy LO, Blenis J. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat Cell Biol. 2005;7:591-600.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 591-600
-
-
MacKeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
32
-
-
34250367067
-
Multiplexing siRNAs to compress RNAi-based screen size in human cells
-
Martin SE, Jones TL, Thomas CL, et al. Multiplexing siRNAs to compress RNAi-based screen size in human cells. Nucleic Acids Res. 2007;35:e57.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Martin, S.E.1
Jones, T.L.2
Thomas, C.L.3
-
33
-
-
33646033137
-
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
-
Moffat J, Grueneberg DA, Yang X, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell. 2006;124:1283-1298.
-
(2006)
Cell
, vol.124
, pp. 1283-1298
-
-
Moffat, J.1
Grueneberg, D.A.2
Yang, X.3
-
34
-
-
23844483215
-
Identification of JAK/STAT signalling components by genome-wide RNA interference
-
Müller P, Kuttenkeuler D, Gesellchen V, Zeidler MP, Boutros M. Identification of JAK/STAT signalling components by genome-wide RNA interference. Nature. 2005;436:871-875.
-
(2005)
Nature
, vol.436
, pp. 871-875
-
-
Müller, P.1
Kuttenkeuler, D.2
Gesellchen, V.3
Zeidler, M.P.4
Boutros, M.5
-
35
-
-
33645306041
-
A loss-of-function RNA interference screen for molecular targets in cancer
-
Ngo VN, Davis RE, Lamy L, et al. A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 2006;441:106-110.
-
(2006)
Nature
, vol.441
, pp. 106-110
-
-
Ngo, V.N.1
Davis, R.E.2
Lamy, L.3
-
36
-
-
0037443054
-
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
-
Pothof J, van Haaften G, Thijssen K, et al. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev. 2003;17:443-448.
-
(2003)
Genes Dev
, vol.17
, pp. 443-448
-
-
Pothof, J.1
van Haaften, G.2
Thijssen, K.3
-
37
-
-
21344456958
-
A fast, simple method for screening radiation susceptibility genes by RNA interference
-
Tsuji AB, Sudo H, Sugyo A, et al. A fast, simple method for screening radiation susceptibility genes by RNA interference. Biochem Biophys Res Commun. 2005;333:1370-1377.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 1370-1377
-
-
Tsuji, A.B.1
Sudo, H.2
Sugyo, A.3
-
38
-
-
33745639254
-
Identification of conserved pathways of DNA-damage response and radiation protection by genomewide RNAi
-
van Haaften G, Romeijn R, Pothof J, et al. Identification of conserved pathways of DNA-damage response and radiation protection by genomewide RNAi. Curr Biol. 2006;16:1344-1350.
-
(2006)
Curr Biol
, vol.16
, pp. 1344-1350
-
-
van Haaften, G.1
Romeijn, R.2
Pothof, J.3
-
39
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook TF, Martin ES, Schlabach MR, et al. A genetic screen for candidate tumor suppressors identifies REST. Cell. 2005;121:837-848.
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
-
40
-
-
27744471940
-
The extract of huanglian, a medicinal herb, induces cell growth arrest and apoptosis by up-regulation of interferon-beta and TNF-alpha in human breast cancer cells
-
Kang JX, Liu J, Wang J, He C, Li FP. The extract of huanglian, a medicinal herb, induces cell growth arrest and apoptosis by up-regulation of interferon-beta and TNF-alpha in human breast cancer cells. Carcinogenesis. 2005;26:1934-1939.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1934-1939
-
-
Kang, J.X.1
Liu, J.2
Wang, J.3
He, C.4
Li, F.P.5
-
41
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
42
-
-
19944427133
-
The Janus kinases (Jaks)
-
Yamaoka K, Saharinen P, Pesu M, Holt VE, 3rd Silvennoinen O, O'Shea JJ. The Janus kinases (Jaks). Genome Biol. 2004;5:253.
-
(2004)
Genome Biol
, vol.5
, pp. 253
-
-
Yamaoka, K.1
Saharinen, P.2
Pesu, M.3
Holt 3rd, V.E.4
Silvennoinen, O.5
O'Shea, J.J.6
-
43
-
-
0027359443
-
Identification of mutations in the coding sequence of the protooncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
Furitsu T, Tsujimura T, Tono T, et al. Identification of mutations in the coding sequence of the protooncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest. 1993;92:1736-1744.
-
(1993)
J Clin Invest
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
-
44
-
-
25844507795
-
Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor
-
Roskoski R, Jr. Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor. Biochem Biophys Res Commun. 2005;337:1-13.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1-13
-
-
Roskoski Jr., R.1
-
45
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
-
Hanke JH, Gardner JP, Dow RL, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem. 1996;271:695-701.
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
-
46
-
-
0035912929
-
Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines
-
Tian G, Cory M, Smith AA, Knight WB. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry. 2001;40:7084-7091.
-
(2001)
Biochemistry
, vol.40
, pp. 7084-7091
-
-
Tian, G.1
Cory, M.2
Smith, A.A.3
Knight, W.B.4
-
47
-
-
0033053383
-
Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents
-
Sudbeck EA, Liu XP, Narla RK, et al. Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents. Clin Cancer Res. 1999;5:1569-1582.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1569-1582
-
-
Sudbeck, E.A.1
Liu, X.P.2
Narla, R.K.3
-
48
-
-
0037156334
-
Photochemical preparation of a pyridone containing tetracycle: A Jak protein kinase inhibitor
-
Thompson JE, Cubbon RM, Cummings RT, et al. Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor. Bioorg Med Chem Lett. 2002;12:1219-1223.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 1219-1223
-
-
Thompson, J.E.1
Cubbon, R.M.2
Cummings, R.T.3
-
49
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan N, Grunberger T, Dadi H, et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature. 1996;379:645-648.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
-
50
-
-
0001123864
-
JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response
-
Wang LH, Kirken RA, Erwin RA, Yu CR, Farrar WL. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response. J Immunol. 1999;162:3897-3904.
-
(1999)
J Immunol
, vol.162
, pp. 3897-3904
-
-
Wang, L.H.1
Kirken, R.A.2
Erwin, R.A.3
Yu, C.R.4
Farrar, W.L.5
-
51
-
-
0035807221
-
Src directly tyrosine- phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway
-
Okutani Y, Kitanaka A, Tanaka T, et al. Src directly tyrosine- phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway. Oncogene. 2001;20:6643-6650.
-
(2001)
Oncogene
, vol.20
, pp. 6643-6650
-
-
Okutani, Y.1
Kitanaka, A.2
Tanaka, T.3
-
52
-
-
0037153476
-
Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis
-
Wilson MB, Schreiner SJ, Choi HJ, Kamens J, Smithgall TE. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis. Oncogene. 2002;21:8075-8088.
-
(2002)
Oncogene
, vol.21
, pp. 8075-8088
-
-
Wilson, M.B.1
Schreiner, S.J.2
Choi, H.J.3
Kamens, J.4
Smithgall, T.E.5
-
53
-
-
33644546402
-
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders
-
Quentmeier H, MacLeod RA, Zaborski M, Drexler HG. JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia. 2006;20:471-476.
-
(2006)
Leukemia
, vol.20
, pp. 471-476
-
-
Quentmeier, H.1
MacLeod, R.A.2
Zaborski, M.3
Drexler, H.G.4
-
54
-
-
0027960979
-
Convergence of signaling by interleukin-3, granulocyte-macrophage colony-stimulating factor, and mast cell growth factor on JAK2 tyrosine kinase
-
Brizzi MF, Zini MG, Aronica MG, Blechman JM, Yarden Y, Pegoraro L. Convergence of signaling by interleukin-3, granulocyte-macrophage colony-stimulating factor, and mast cell growth factor on JAK2 tyrosine kinase. J Biol Chem. 1994;269:31680-31684.
-
(1994)
J Biol Chem
, vol.269
, pp. 31680-31684
-
-
Brizzi, M.F.1
Zini, M.G.2
Aronica, M.G.3
Blechman, J.M.4
Yarden, Y.5
Pegoraro, L.6
-
55
-
-
0030068012
-
JAK2 is constitutively associated with c-Kit and is phosphorylated in response to stem cell factor
-
Linnekin D, Weiler SR, Mou S, et al. JAK2 is constitutively associated with c-Kit and is phosphorylated in response to stem cell factor. Acta Haematol. 1996;95:224-228.
-
(1996)
Acta Haematol
, vol.95
, pp. 224-228
-
-
Linnekin, D.1
Weiler, S.R.2
Mou, S.3
-
56
-
-
0029873587
-
JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor
-
Weiler SR, Mou S, DeBerry CS, et al. JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor. Blood. 1996;87:3688-3693.
-
(1996)
Blood
, vol.87
, pp. 3688-3693
-
-
Weiler, S.R.1
Mou, S.2
DeBerry, C.S.3
-
57
-
-
0242332186
-
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor
-
Changelian PS, Flanagan ME, Ball DJ, et al. Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science. 2003;302:875-878.
-
(2003)
Science
, vol.302
, pp. 875-878
-
-
Changelian, P.S.1
Flanagan, M.E.2
Ball, D.J.3
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