Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

Leukemia

Volumn 11, Issue 10, 1997, Pages 1605-1609

  Yokota, S ^a   Kiyoi, H ^b   Nakao, M ^a   Iwai, T ^a   Misawa, T ^a   Okuda, T ^a   Sonoda, Y ^a   Abe, T ^a   Kahsima, K ^a   Matsuo, Y ^c   Naoe, T ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

AML; FLT3; MDS; Mutation; Tandem duplication

Indexed keywords

PROTEIN TYROSINE KINASE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BURKITT LYMPHOMA; CANCER GRADING; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; EXON; GENE DUPLICATION; GENE MUTATION; HAIRY CELL LEUKEMIA; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; NONHODGKIN LYMPHOMA; POLYMERASE CHAIN REACTION; PRELEUKEMIA; PRIORITY JOURNAL; PROTEIN DOMAIN; T CELL LEUKEMIA; TANDEM REPEAT;

EID: 16944365287     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400812     Document Type: Article

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