Chimeric proteins can exceed the sum of their parts: implications for evolution and protein design

Nature Biotechnology

Volumn 15, Issue 5, 1997, Pages 439-443

  Campbell, Robert K ^a,b   Bergert, Elizabeth R ^c   Wang, Yanhong ^a   Morris, John C ^c   Moyle, William R ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b Ares Advanced Technology   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Chimeric proteins; Evolution; Human chorionic gonadotropin; Protein protein interactions; Thyrotropin

Indexed keywords

CHIMERIC PROTEIN; CHORIONIC GONADOTROPIN; FOLLITROPIN; THYROTROPIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EVOLUTION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0031003340     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0597-439     Document Type: Article

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