-
1
-
-
33746342994
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol. Rev. 212: 8-27.
-
(2006)
Immunol. Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
Yagi, H.4
Hori, S.5
Fehervari, Z.6
Shimizu, J.7
Takahashi, T.8
Nomura, T.9
-
3
-
-
33746377279
-
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
-
Izcue, A., J. L. Coombes, and F. Powrie. 2006. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol. Rev. 212: 256-271.
-
(2006)
Immunol. Rev
, vol.212
, pp. 256-271
-
-
Izcue, A.1
Coombes, J.L.2
Powrie, F.3
-
4
-
-
33746347017
-
Natural regulatory T cells and parasites: A common quest for host homeostasis
-
Belkaid, Y., R. B. Blank, and I. Suffia. 2006. Natural regulatory T cells and parasites: a common quest for host homeostasis. Immunol. Rev. 212: 287-300.
-
(2006)
Immunol. Rev
, vol.212
, pp. 287-300
-
-
Belkaid, Y.1
Blank, R.B.2
Suffia, I.3
-
5
-
-
33746383248
-
Regulatory T cells in virus infections
-
Rouse, B. T., P. P. Sarangi, and S. Suvas. 2006. Regulatory T cells in virus infections. Immunol. Rev. 212: 272-286.
-
(2006)
Immunol. Rev
, vol.212
, pp. 272-286
-
-
Rouse, B.T.1
Sarangi, P.P.2
Suvas, S.3
-
6
-
-
33746599842
-
Regulatory T cells in cancer
-
Beyer, M., and J. L. Schultze. 2006. Regulatory T cells in cancer. Blood 108: 804-811.
-
(2006)
Blood
, vol.108
, pp. 804-811
-
-
Beyer, M.1
Schultze, J.L.2
-
7
-
-
32644460091
-
+ regulatory T lymphocytes in bone marrow transplantation
-
+ regulatory T lymphocytes in bone marrow transplantation. Semin. Immunol. 18: 128-135.
-
(2006)
Semin. Immunol
, vol.18
, pp. 128-135
-
-
Joffre, O.1
van Meerwijk, J.P.M.2
-
11
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
-
Hsieh, C. S., Y. Zheng, Y. Liang, J. D. Fontenot, and A. Y. Rudensky. 2006. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat. Immunol. 7: 401-410.
-
(2006)
Nat. Immunol
, vol.7
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
12
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.-J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
14
-
-
12344307563
-
+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
-
+ regulatory T cells in vivo requires B7 costimulation, but not the thymus. J. Exp. Med. 201: 127-137.
-
(2005)
J. Exp. Med
, vol.201
, pp. 127-137
-
-
Liang, S.1
Alard, P.2
Zhao, Y.3
Parnell, S.4
Clark, S.L.5
Kosiewicz, M.M.6
-
15
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou, I., and H. von Boehmer. 2004. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199: 1401-1408.
-
(2004)
J. Exp. Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
von Boehmer, H.2
-
18
-
-
0029835390
-
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
-
Laufer, T. M., J. DeKoning, J. S. Markowitz, D. Lo, and L. H. Glimcher. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383: 81-85.
-
(1996)
Nature
, vol.383
, pp. 81-85
-
-
Laufer, T.M.1
DeKoning, J.2
Markowitz, J.S.3
Lo, D.4
Glimcher, L.H.5
-
19
-
-
0035282767
-
Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells
-
Capone, M., P. Romagnoli, F. Beermann, H. R. MacDonald, and J. P. M. van Meerwijk. 2001. Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells. Blood 97: 1336-1342.
-
(2001)
Blood
, vol.97
, pp. 1336-1342
-
-
Capone, M.1
Romagnoli, P.2
Beermann, F.3
MacDonald, H.R.4
van Meerwijk, J.P.M.5
-
20
-
-
0037239006
-
In vivo unresponsiveness of T lymphocyte induced by thymic medullary epithelium requires antigen presentation by radioresistant cells
-
Hudrisier, D., S. Feau, V. Bonnet, P. Romagnoli, and J. P. M. van Meerwijk. 2003. In vivo unresponsiveness of T lymphocyte induced by thymic medullary epithelium requires antigen presentation by radioresistant cells. Immunology 108: 24-31.
-
(2003)
Immunology
, vol.108
, pp. 24-31
-
-
Hudrisier, D.1
Feau, S.2
Bonnet, V.3
Romagnoli, P.4
van Meerwijk, J.P.M.5
-
22
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2: 301-306.
-
(2001)
Nat. Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
23
-
-
0036568942
-
+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol. 168: 4399-4405.
-
(2002)
J. Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
Misaki, Y.2
Yamauchi, M.3
Tsunekawa, S.4
Setoguchi, K.5
Miyazaki, J.-I.6
Yamamoto, K.7
-
24
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., A. Sarukhan, L. Klein, and H. von Boehmer. 2002. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3: 756-763.
-
(2002)
Nat. Immunol
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
von Boehmer, H.4
-
25
-
-
27544446622
-
+ regulatory T cells in the absence of interleukin 2 signaling
-
+ regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6: 1152-1159.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1152-1159
-
-
D'Cruz, L.M.1
Klein, L.2
-
26
-
-
33744786828
-
+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage
-
+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage. Proc. Natl. Acad. Sci. USA 103: 8453-8458.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8453-8458
-
-
Cabarrocas, J.1
Cassan, C.2
Magnusson, F.3
Piaggio, E.4
Mars, L.5
Derbinski, J.6
Kyewski, B.7
Gross, D.-A.8
Salomon, B.L.9
Khazaie, K.10
-
27
-
-
34248598295
-
+ medullary thymic epithelial cells
-
+ medullary thymic epithelial cells. Nat. Immunol. 8: 351-358.
-
(2007)
Nat. Immunol
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.M.2
Vollmann, E.H.3
Hinterberger, M.4
Emmerich, J.5
Swee, L.K.6
Rolink, A.7
Klein, L.8
-
28
-
-
9244244736
-
Number of T Reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
van Santen, H.-M., C. Benoist, and D. Mathis. 2004. Number of T Reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J. Exp. Med. 200: 1221-1230.
-
(2004)
J. Exp. Med
, vol.200
, pp. 1221-1230
-
-
van Santen, H.-M.1
Benoist, C.2
Mathis, D.3
-
29
-
-
33745848463
-
Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR repertoire
-
Ribot, J., P. Romagnoli, and J. P. M. van Meerwijk. 2006. Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR repertoire. J. Immunol. 177: 1101-1107.
-
(2006)
J. Immunol
, vol.177
, pp. 1101-1107
-
-
Ribot, J.1
Romagnoli, P.2
van Meerwijk, J.P.M.3
-
32
-
-
22744441535
-
How the T cell repertoire becomes peptide and MHC specific
-
Huseby, E. S., J. White, F. Crawford, T. Vass, D. Becker, C. Pinilla, P. Marrack, and J. W. Kappler. 2005. How the T cell repertoire becomes peptide and MHC specific. Cell 122: 247-260.
-
(2005)
Cell
, vol.122
, pp. 247-260
-
-
Huseby, E.S.1
White, J.2
Crawford, F.3
Vass, T.4
Becker, D.5
Pinilla, C.6
Marrack, P.7
Kappler, J.W.8
-
33
-
-
33750113432
-
Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide
-
Huseby, E. S., F. Crawford, J. White, P. Marrack, and J. W. Kappler. 2006. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat. Immunol. 7: 1191-1199.
-
(2006)
Nat. Immunol
, vol.7
, pp. 1191-1199
-
-
Huseby, E.S.1
Crawford, F.2
White, J.3
Marrack, P.4
Kappler, J.W.5
-
34
-
-
0141593568
-
Negative selection imparts peptide specificity to the mature T cell repertoire
-
Huseby, E. S., F. Crawford, J. White, J. Kappler, and P. Marrack. 2003. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc. Natl. Acad. Sci. USA 100: 11565-11570.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11565-11570
-
-
Huseby, E.S.1
Crawford, F.2
White, J.3
Kappler, J.4
Marrack, P.5
-
35
-
-
0024450056
-
Positive selection of the T cell repertoire: Where and when does it occur?
-
Benoist, C., and D. Mathis. 1989. Positive selection of the T cell repertoire: where and when does it occur? Cell 58: 1027-1033.
-
(1989)
Cell
, vol.58
, pp. 1027-1033
-
-
Benoist, C.1
Mathis, D.2
-
37
-
-
0031569124
-
Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice
-
DeKoning, J., L. DiMolfetto, C. Reilly, Q. Wei, W. L. Havran, and D. Lo. 1997. Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice. J. Immunol. 158: 2558-2566.
-
(1997)
J. Immunol
, vol.158
, pp. 2558-2566
-
-
DeKoning, J.1
DiMolfetto, L.2
Reilly, C.3
Wei, Q.4
Havran, W.L.5
Lo, D.6
-
39
-
-
15844388113
-
Thymic cortical epithelium induces self tolerance
-
Goldman, K. P., C. S. Park, M. Kim, P. Matzinger, and C. C. Anderson. 2005. Thymic cortical epithelium induces self tolerance. Eur. J. Immunol. 35: 709-717.
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 709-717
-
-
Goldman, K.P.1
Park, C.S.2
Kim, M.3
Matzinger, P.4
Anderson, C.C.5
-
40
-
-
1642495787
-
Central tolerance to self-antigen expressed by cortical epithelial cells
-
Mayerova, D., and K. A. Hogquist. 2004. Central tolerance to self-antigen expressed by cortical epithelial cells. J. Immunol. 172: 851-856.
-
(2004)
J. Immunol
, vol.172
, pp. 851-856
-
-
Mayerova, D.1
Hogquist, K.A.2
-
41
-
-
22344450566
-
The timing of TCR α expression critically influences T cell development and selection
-
Baldwin, T. A., M. M. Sandau, S. C. Jameson, and K. A. Hogquist. 2005. The timing of TCR α expression critically influences T cell development and selection. J. Exp. Med. 202: 111-121.
-
(2005)
J. Exp. Med
, vol.202
, pp. 111-121
-
-
Baldwin, T.A.1
Sandau, M.M.2
Jameson, S.C.3
Hogquist, K.A.4
-
42
-
-
0033136289
-
Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
-
Laufer, T. M., L. Fan, and L. H. Glimcher. 1999. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J. Immunol. 162: 5078-5084.
-
(1999)
J. Immunol
, vol.162
, pp. 5078-5084
-
-
Laufer, T.M.1
Fan, L.2
Glimcher, L.H.3
-
43
-
-
0028935078
-
Cell surface expression of class II MHC proteins bound by a single peptide
-
Ignatowicz, L., G. Winslow, J. Bill, J. Kappler, and P. Marrack. 1995. Cell surface expression of class II MHC proteins bound by a single peptide. J. Immunol. 154: 3852-3862.
-
(1995)
J. Immunol
, vol.154
, pp. 3852-3862
-
-
Ignatowicz, L.1
Winslow, G.2
Bill, J.3
Kappler, J.4
Marrack, P.5
-
44
-
-
0028348196
-
Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine α 1(II)-CB11 in H-2q mice
-
Brand, D. D., L. K. Myers, K. Terato, K. B. Whittington, J. M. Stuart, A. H. Kang, and E. F. Rosloniec. 1994. Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine α 1(II)-CB11 in H-2q mice. J. Immunol. 152: 3088-3097.
-
(1994)
J. Immunol
, vol.152
, pp. 3088-3097
-
-
Brand, D.D.1
Myers, L.K.2
Terato, K.3
Whittington, K.B.4
Stuart, J.M.5
Kang, A.H.6
Rosloniec, E.F.7
-
45
-
-
0000425845
-
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
-
Vassar, R., M. Rosenberg, S. Ross, A. Tyner, and E. Fuchs. 1989. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 86: 1563-1567.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 1563-1567
-
-
Vassar, R.1
Rosenberg, M.2
Ross, S.3
Tyner, A.4
Fuchs, E.5
-
46
-
-
0030601344
-
Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis
-
Rosloniec, E. F., K. B. Whittington, D. D. Brand, L. K. Myers, and J. M. Stuart. 1996. Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis. Cell. Immunol. 172: 21-28.
-
(1996)
Cell. Immunol
, vol.172
, pp. 21-28
-
-
Rosloniec, E.F.1
Whittington, K.B.2
Brand, D.D.3
Myers, L.K.4
Stuart, J.M.5
-
47
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski, J., A. Schulte, B. Kyewski, and L. Klein. 2001. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2: 1032-1039.
-
(2001)
Nat. Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
48
-
-
0019468220
-
Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
-
Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J. Immunol. 126: 1614-1619.
-
(1981)
J. Immunol
, vol.126
, pp. 1614-1619
-
-
Taswell, C.1
-
51
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
53
-
-
8344275995
-
+ regulatory T cells
-
+ regulatory T cells. Int. Immunol. 16: 1643-1656.
-
(2004)
Int. Immunol
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
Yamazaki, S.4
Kitawaki, T.5
Hori, S.6
Maeda, M.7
Onodera, M.8
Uchiyama, T.9
Fujii, S.10
Sakaguchi, S.11
-
54
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot, J. D., J. P. Rasmussen, L. M. Williams, J. L. Dooley, A. G. Farr, and A. Y. Rudensky. 2005. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 22: 329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
56
-
-
4544258485
-
Self-representation in the thymus: An extended view
-
Kyewski, B., and J. Derbinski. 2004. Self-representation in the thymus: an extended view. Nat. Rev. Immunol. 4: 688-698.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 688-698
-
-
Kyewski, B.1
Derbinski, J.2
-
57
-
-
23844558032
-
The cellular mechanism of AIRE control of T cell tolerance
-
Anderson, M. S., E. S. Venanzi, Z. Chen, S. P. Berzins, C. Benoist, and D. Mathis. 2005. The cellular mechanism of AIRE control of T cell tolerance. Immunity 23: 227-239.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
58
-
-
0024381358
-
A nondeletional mechanism of thymic self tolerance
-
Ramsdell, F., T. Lantz, and B. J. Fowlkes. 1989. A nondeletional mechanism of thymic self tolerance. Science 246: 1038-1041.
-
(1989)
Science
, vol.246
, pp. 1038-1041
-
-
Ramsdell, F.1
Lantz, T.2
Fowlkes, B.J.3
-
60
-
-
0030058657
-
The repertoire of T cells shaped by a single MHC/peptide ligand
-
Ignatowicz, L., J. Kappler, and P. Marrack. 1996. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 84: 521-529.
-
(1996)
Cell
, vol.84
, pp. 521-529
-
-
Ignatowicz, L.1
Kappler, J.2
Marrack, P.3
|