Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding

Journal of Biological Chemistry

Volumn 283, Issue 3, 2008, Pages 1480-1491

  Yang, Keum Jin ^a   Shin, Sanghee ^a   Piao, Longzhen ^a   Shin, Eulsoon ^a   Li, Yuwen ^a   Kyeong, Ah Park ^a   Hee, Sun Byun ^a   Won, Minho ^a   Hong, Janghee ^a   Gi, Ryang Kweon ^a   Gang, Min Hur ^a   Jeong, Ho Seok ^a   Chun, Taehoon ^b   Brazil, Derek P ^c   Hemmings, Brian A ^d   Park, Jongsun ^a  

^a Chungnam National University   (South Korea)

^b Korea University   (South Korea)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; CELL CULTURE; INSULIN; PHOSPHORYLATION; PROTEINS; TUMORS;

TUMOR SAMPLES; TYROSINE PHOSPHORYLATION;

ENZYME KINETICS;

ANTIBODY; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN SH2; PROTEIN TYROSINE KINASE; TYROSINE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION;

CELL LINE; DISEASE; ENZYME ACTIVATION; ENZYME STABILITY; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LEUPEPTINS; MODELS, BIOLOGICAL; MUTANT PROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-CRK; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECOMBINANT FUSION PROTEINS; SRC HOMOLOGY DOMAINS; SUBCELLULAR FRACTIONS;

EID: 38349168971     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706361200     Document Type: Article

References (67)

1. Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B., and Cohen, P. (1997) Curr. Biol. 7, 261-269
2. Kikani, C. K., Dong, L. Q., and Liu, F. (2005) J. Cell Biochem. 96, 1157-1162
3. Fayard, E., Tintignac, L. A., Baudry, A., and Hemmings, B. A. (2005) J. Cell Sci. 118, 5675-5678
4. Mora, A., Komander, D., van Aalten, D. M., and Alessi, D. R. (2004) Semin. Cell Dev. Biol. 15, 161-170
5. Hinton, H. J., Alessi, D. R., and Cantrell, D. A. (2004) Nat. Immunol. 5, 539-545
6. Lawlor, M. A., Mora, A., Ashby, P. R., Williams, M. R., Murray-Tait, V., Malone, L., Prescott, A. R., Lucocq, J. M., and Alessi, D. R. (2002) EMBO J. 21, 3728-3738
7. Williams, M. R., Arthur, J. S., Balendran, A., van der Kaay, J., Poli, V., Cohen, P., and Alessi, D. R. (2000) Curr. Biol. 10, 439-448
8. Stephens, L., Anderson, K., Stokoe, D., Erdjument-Bromage, H., Painter, G. F., Holmes, A. B., Gaffney, P. R., Reese, C. B., McCormick, F., Tempst, P., Coadwell, J., and Hawkins, P. T. (1998) Science 279, 710-714
9. Alessi, D. R., Deak, M., Casamayor, A., Caudwell, F. B., Morrice, N., Norman, D. G., Gaffney, P., Reese, C. B., MacDougall, C. N., Harbison, D., Ashworth, A., and Bownes, M. (1997) Curr. Biol. 7, 776-789
10. Yang, J., Cron, P., Thompson, V., Good, V. M., Hess, D., Hemmings, B. A., and Barford, D. (2002) Mol. Cell 9, 1227-1240
11. Yang, J., Cron, P., Good, V. M., Thompson, V., Hemmings, B. A., and Barford, D. (2002) Nat. Struct. Biol. 9, 940-944
12. Casamayor, A., Morrice, N. A., and Alessi, D. R. (1999) Biochem. J. 342, 287-292
13. Park, J., Hill, M. M., Hess, D., Brazil, D. P., Hofsteenge, J., and Hemmings, B. A. (2001) J. Biol. Chem. 276, 37459-37471
14. Prasad, N., Topping, R. S., Zhou, D., and Decker, S. J. (2000) Biochemistry 39, 6929-6935
15. Grillo, S., Gremeaux, T., Casamayor, A., Alessi, D. R., Le Marchand-Brustel, Y., and Tanti, J. F. (2000) Eur. J. Biochem. 267, 6642-6649
16. Wei, Q., and Xia, Y. (2005) J. Biol. Chem. 280, 18081-18086
17. Fujita, N., Sato, S., Ishida, A., and Tsuruo, T. (2002) J. Biol. Chem. 277, 10346-10353
18. Roche, S., McGlade, J., Jones, M., Gish, G. D., Pawson, T., and Courtneidge, S. A. (1996) EMBO J. 15, 4940-4948
19. Park, K. A., Byun, H. S., Won, M., Yang, K. J., Shin, S., Piao, L., Kim, J. M., Woon, W. H., Junn, E., Park, J., Seok, J. H., and Hur, G. M. (2007) Carcinogenesis, 28, 71-80
20. Posner, B. I., Faure, R., Burgess, J. W., Bevan, A. P., Lachance, D., Zhang-Sun, G., Fantus, I. G., Ng, J. B., Hall, D. A., and Lum, B. S. (1994) J. Biol. Chem. 269, 4596-4604
21. Park, J., Leong, M. L., Buse, P., Maiyar, A. C., Firestone, G. L., and Hemmings, B. A. (1999) EMBO J. 18, 3024-3033
22. Elias, J. M., Margiotta, M., and Gaborc, D. (1989) Am. J. Clin. Pathol. 92, 62-67
23. Fiory, F., Alberobello, A. T., Miele, C., Oriente, F., Esposito, I., Corbo, V., Ruvo, M., Tizzano, B., Rasmussen, T. E., Gammeltoft, S., Formisano, P., and Beguinot, F. (2005) Mol. Cell Biol. 25, 10803-10814
24. Pawson, T. (2004) Cell 116, 191-203
25. Latour, S., Roncagalli, R., Chen, R., Bakinowski, M., Shi, X., Schwartzberg, P. L., Davidson, D., and Veillette, A. (2003) Nat. Cell Biol. 5, 149-154
26. Donaldson, L. W., Gish, G., Pawson, T., Kay, L. E., and Forman-Kay, J. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 14053-14058
27. Basso, A. D., Solit, D. B., Chiosis, G., Giri, B., Tsichlis, P., and Rosen, N. (2002) J. Biol. Chem. 277, 39858-39866
28. Neckers, L., Mimnaugh, E., and Schulte, T. W. (1999) Drug Resist. Updates 2, 165-172
29. Neckers, L., Schulte, T. W., and Mimnaugh, E. (1999) Invest. New Drugs 17, 361-373
30. Kobayashi, T., and Cohen, P. (1999) Biochem. J. 339, 319-328
31. Ammirante, M., Rosati, A., Gentilella, A., Festa, M., Petrella, A., Marzullo, L., Poscale, M., Belisaria, M. A., Leone, A., and Turco, M. C. (2007) Oncogene, in press
32. Komander, D., Kular, G. S., Bain, J., Elliott, M., Alessi, D. R., and Van Aalten, D. M. (2003) Biochem. J. 375, 255-262
33. Xie, Z., Yuan, H., Yin, Y., Zeng, X., Bai, R., and Glazer, R. I. (2006) BMC Cancer 6, 77
34. Zeng, Z., Samudio, I. J., Zhang, W., Estrov, Z., Pelicano, H., Harris, D., Frolova, O., Hail, N., Jr., Chen, W., Kornblau, S. M., Huang, P., Lu, Y., Mills, G. B., Andreeff, M., and Konopleva, M. (2006) Cancer Res. 66, 3737-3746
35. Brunet, A., Park, J., Tran, H., Hu, L. S., Hemmings, B. A., and Greenberg, M. E. (2001) Mol. Cell Biol. 21, 952-965
36. Pullen, N., Dennis, P. B., Andjelkovic, M., Dufner, A., Kozma, S. C., Hemmings, B. A., and Thomas, G. (1998) Science 279, 707-710
37. Chou, M. M., Hou, W., Johnson, J., Graham, L. K., Lee, M. H., Chen, C. S., Newton, A. C., Schaffhausen, B. S., and Toker, A. (1998) Curr. Biol. 8, 1069-1077
38. Taniyama, Y., Weber, D. S., Rocic, P., Hilenski, L., Akers, M. L., Park, J., Hemmings, B. A., Alexander, R. W., and Griendling, K. K. (2003) Mol. Cell Biol. 23, 8019-8029
39. Kim, D. W., Hwang, J. H., Suh, J. M., Kim, H., Song, J. H., Hwang, E. S., Hwang, I. Y., Park, K. C., Chung, H. K., Kim, J. M., Park, J., Hemmings, B. A., and Shong, M. (2003) Mol. Endocrinol. 17, 1382-1394
40. Wong, B. R., Besser, D., Kim, N., Arron, J. R., Vologodskaia, M., Hanafusa, H., and Choi, Y. (1999) Mol. Cell 4, 1041-1049
41. Van Slyke, P., Coll, M. L., Master, Z., Kim, H., Filmus, J., and Dumont, D. J. (2005) Mol. Cell Biol. 25, 3831-3841
42. Mehdi, M. Z., Pandey, N. R., Pandey, S. K., and Srivastava, A. K. (2005) Antioxid. Redox. Signal. 7, 1014-1020
43. Azar, Z. M., Mehdi, M. Z., and Srivastava, A. K. (2006) Can. J. Physiol. Pharmacol. 84, 777-786
44. Chen, R., Kim, O., Yang, J., Sato, K., Eisenmann, K. M., McCarthy, J., Chen, H., and Qiu, Y. (2001) J. Biol. Chem. 276, 31858-31862
45. Sato, S., Fujita, N., and Tsuruo, T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 10832-10837
46. Brouet, A., Sonveaux, P., Dessy, C., Moniotte, S., Balligand, J. L., and Feron, O. (2001) Circ. Res. 89, 866-873
47. Fontana, J., Fulton, D., Chen, Y., Fairchild, T. A., McCabe, T. J., Fujita, N., Tsuruo, T., and Sessa, W. C. (2002) Circ. Res. 90, 866-873
48. Sato, S., Fujita, N., and Tsuruo, T. (2002) J. Biol. Chem. 277, 39360-39367
49. Fujita, N., and Tsuruo, T. (2003) Cancer Chemother. Pharmacol. 52, Suppl. 1, 24-28
50. Yun, B. G., and Matts, R. L. (2005) Cell. Signal. 17, 1477-1485
51. Meares, G. P., Zmijewska, A. A., and Jope, R. S. (2004) FEBS Lett. 574, 181-186
52. Dummler, B., and Hemmings, B. A. (2007) Biochem. Soc. Trans. 35, 231-235
53. Anderson, K. E., Coadwell, J., Stephens, L. R., and Hawkins, P. T. (1998) Curr. Biol. 8, 684-691
54. Andjelkovic, M., Maira, S. M., Cron, P., Parker, P. J., and Hemmings, B. A. (1999) Mol. Cell Biol. 19, 5061-5072
55. Filippa, N., Sable, C. L., Hemmings, B. A., and Van Obberghen, E. (2000) Mol. Cell Biol. 20, 5712-5721
56. Kim, S., Jee, K., Kim, D., Koh, H., and Chung, J. (2001) J. Biol. Chem. 276, 12864-12870
57. Currie, R. A., Walker, K. S., Gray, A., Deak, M., Casamayor, A., Downes, C. P., Cohen, P., Alessi, D. R., and Lucocq, J. (1999) Biochem. J. 337, 575-583
58. Calleja, V., Alcor, D., Laguerre, M., Park, J., Vojnovic, B., Hemmings, B. A., Downward, J., Parker, P. J., and Larijani, B. (2007) PLoS Biol. 5, 780-791
59. Balendran, A., Biondi, R. M., Cheung, P. C., Casamayor, A., Deak, M., and Alessi, D. R. (2000) J. Biol. Chem. 275, 20806-20813
60. Biondi, R. M., Cheung, P. C., Casamayor, A., Deak, M., Currie, R. A., and Alessi, D. R. (2000) EMBO J. 19, 979-988
61. Biondi, R. M., Kieloch, A., Currie, R. A., Deak, M., and Alessi, D. R. (2001) EMBO J. 20, 4380-4390
62. Collins, B. J., Deak, M., Arthur, J. S., Armit, L. J., and Alessi, D. R. (2003) EMBO J. 22, 4202-4211
63. Frodin, M., Jensen, C. J., Merienne, K., and Gammeltoft, S. (2000) EMBO J. 19, 2924-2934
64. Frodin, M., Antal, T. L., Dummler, B. A., Jensen, C. J., Deak, M., Gammeltoft, S., and Biondi, R. M. (2002) EMBO J. 21, 5396-5407
65. Ciocca, D. R., Fuqua, S. A., Lock-Lim, S., Toft, D. O., Welch, W. J., and McGuire, W. L. (1992) Cancer Res. 52, 3648-3654
66. Ferrarini, M., Heltai, S., Zocchi, M. R., and Rugarli, C. (1992) Int. J. Cancer 51, 613-619
67. Yufu, Y., Nishimura, J., and Nawata, H. (1992) Leuk. Res. 16, 597-605