Requirement of phospholipase Cγ, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: Evidence for the existence of Ras-dependent and Ras-independent pathways

EMBO Journal

Volumn 15, Issue 18, 1996, Pages 4940-4948

  Roche, Serge ^a,b   McGlade, Jane ^c,d   Jones, Margaret ^a   Gish, Gerald D ^c   Pawson, Tony ^c,d   Courtneidge, Sara A ^a,e  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIV MONTPELLIER   (France)

^c MOUNT SINAI HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e SUGEN INC   (United States)

Author keywords

DNA synthesis; PDGF receptor; Ras; Signalling; Tyrosine kinase

Indexed keywords

PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE PHOSPHATASE; RAS PROTEIN;

ARTICLE; CELL CYCLE S PHASE; DNA SYNTHESIS; DRUG ACTIVITY; FIBROBLAST; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0029814709     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00874.x     Document Type: Article

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