-
1
-
-
8144228424
-
PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus
-
Ahn JY, Hong R, Liu X, Ye K. 2004. PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus. EMBO J 23:3995-4006.
-
(2004)
EMBO J
, vol.23
, pp. 3995-4006
-
-
Ahn, J.Y.1
Hong, R.2
Liu, X.3
Ye, K.4
-
2
-
-
0032482374
-
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
-
Anderson KE, Coadwell J, Stephens LR, Hawkins PT. 1998. Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr Biol 8:684-691.
-
(1998)
Curr Biol
, vol.8
, pp. 684-691
-
-
Anderson, K.E.1
Coadwell, J.2
Stephens, L.R.3
Hawkins, P.T.4
-
3
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. 1997. Role of translocation in the activation and function of protein kinase B. J Biol Chem 272:31515-31524.
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
4
-
-
21844479572
-
Roles of Pdk1p, a fission yeast protein related to phosphoinositide- dependent protein kinase, in the regulation of mitosis and cytokinesis
-
Bimbo A, Liu J, Balasubramanian MK. 2005. Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesis. Mol Biol Cell 16:3162-3175.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3162-3175
-
-
Bimbo, A.1
Liu, J.2
Balasubramanian, M.K.3
-
5
-
-
1542286168
-
Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation
-
Biondi RM. 2004. Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation. Trends Biochem Sci 29:136-142.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 136-142
-
-
Biondi, R.M.1
-
6
-
-
0033199841
-
Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: Identification of five sites of phosphorylation in vivo
-
Casamayor A, Morrice NA, Alessi DR. 1999. Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: Identification of five sites of phosphorylation in vivo. Biochem J 342 (Pt 2):287-292.
-
(1999)
Biochem J
, vol.342
, Issue.PART 2
, pp. 287-292
-
-
Casamayor, A.1
Morrice, N.A.2
Alessi, D.R.3
-
7
-
-
0030841793
-
PDK1, one of the missing links in insulin signal transduction?
-
Cohen P, Alessi DR, Cross DA. 1997. PDK1, one of the missing links in insulin signal transduction? FEBS Lett 410:3-10.
-
(1997)
FEBS Lett
, vol.410
, pp. 3-10
-
-
Cohen, P.1
Alessi, D.R.2
Cross, D.A.3
-
8
-
-
0035226508
-
Lipids and signal transduction in the nucleus
-
Dygas A, Baranska J. 2001. Lipids and signal transduction in the nucleus. Acta Biochim Pol 48:541-549.
-
(2001)
Acta Biochim Pol
, vol.48
, pp. 541-549
-
-
Dygas, A.1
Baranska, J.2
-
9
-
-
0034676303
-
Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival
-
Flynn P, Wongdagger M, Zavar M, Dean NM, Stokoe D. 2000. Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival. Curr Biol 10:1439-1442.
-
(2000)
Curr Biol
, vol.10
, pp. 1439-1442
-
-
Flynn, P.1
Wongdagger, M.2
Zavar, M.3
Dean, N.M.4
Stokoe, D.5
-
10
-
-
2442681621
-
The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development
-
Hinton HJ, Alessi DR, Cantrell DA. 2004. The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development. Nat Immunol 5:539-545.
-
(2004)
Nat Immunol
, vol.5
, pp. 539-545
-
-
Hinton, H.J.1
Alessi, D.R.2
Cantrell, D.A.3
-
11
-
-
8144228588
-
Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates
-
Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, Peter Downes C, Safrany ST, Alessi DR, van Aalten DM. 2004. Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates. Embo J 23:3918-3928.
-
(2004)
Embo J
, vol.23
, pp. 3918-3928
-
-
Komander, D.1
Fairservice, A.2
Deak, M.3
Kular, G.S.4
Prescott, A.R.5
Peter Downes, C.6
Safrany, S.T.7
Alessi, D.R.8
Van Aalten, D.M.9
-
12
-
-
14744301997
-
Leucine-rich nuclear-export signals: Born to be weak
-
Kutay U, Guttinger S. 2005. Leucine-rich nuclear-export signals: Born to be weak. Trends Cell Biol 15:121-124.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 121-124
-
-
Kutay, U.1
Guttinger, S.2
-
13
-
-
15944410614
-
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation
-
Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S. 2005. PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science 308:114-118.
-
(2005)
Science
, vol.308
, pp. 114-118
-
-
Lee, K.Y.1
D'Acquisto, F.2
Hayden, M.S.3
Shim, J.H.4
Ghosh, S.5
-
14
-
-
0344270855
-
Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function
-
Lim MA, Kikani CK, Wick MJ, Dong LQ. 2003. Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function. Proc Natl Acad Sci USA 100:14006-140011.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14006-140011
-
-
Lim, M.A.1
Kikani, C.K.2
Wick, M.J.3
Dong, L.Q.4
-
15
-
-
0037038704
-
The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism
-
Makris C, Voisin L, Giasson E, Tudan C, Kaplan DR, Meloche S. 2002. The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism. Oncogene 21:7891-7896.
-
(2002)
Oncogene
, vol.21
, pp. 7891-7896
-
-
Makris, C.1
Voisin, L.2
Giasson, E.3
Tudan, C.4
Kaplan, D.R.5
Meloche, S.6
-
16
-
-
0037441468
-
Nuclear lipids: New functions for old molecules?
-
Martelli AM, Tabellini G, Borgatti P, Bortul R, Capitani S, Neri LM. 2003. Nuclear lipids: New functions for old molecules? J Cell Biochem 88:455-461.
-
(2003)
J Cell Biochem
, vol.88
, pp. 455-461
-
-
Martelli, A.M.1
Tabellini, G.2
Borgatti, P.3
Bortul, R.4
Capitani, S.5
Neri, L.M.6
-
18
-
-
0035188415
-
Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha
-
Minami T, Hara K, Oshiro N, Ueoku S, Yoshino K, Tokunaga C, Shirai Y, Saito N, Gout I, Yonezawa K. 2001. Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha. Genes Cells 6: 1003-1015.
-
(2001)
Genes Cells
, vol.6
, pp. 1003-1015
-
-
Minami, T.1
Hara, K.2
Oshiro, N.3
Ueoku, S.4
Yoshino, K.5
Tokunaga, C.6
Shirai, Y.7
Saito, N.8
Gout, I.9
Yonezawa, K.10
-
19
-
-
1342342993
-
PDK1, the master regulator of AGC kinase signal transduction
-
Mora A, Komander D, van Aalten DM, Alessi DR. 2004. PDK1, the master regulator of AGC kinase signal transduction. Semin Cell Dev Biol 15:161-170.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 161-170
-
-
Mora, A.1
Komander, D.2
Van Aalten, D.M.3
Alessi, D.R.4
-
20
-
-
0032797276
-
Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells
-
Neri LM, Martelli AM, Borgatti P, Colamussi ML, Marchisio M, Capitani S. 1999. Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells. Faseb J 13:2299-2310.
-
(1999)
Faseb J
, vol.13
, pp. 2299-2310
-
-
Neri, L.M.1
Martelli, A.M.2
Borgatti, P.3
Colamussi, M.L.4
Marchisio, M.5
Capitani, S.6
-
21
-
-
0037057801
-
The nuclear phosphoinositide 3-kinase/AKT pathway: A new second messenger system
-
Neri LM, Borgatti P, Capitani S, Martelli AM. 2002. The nuclear phosphoinositide 3-kinase/AKT pathway: A new second messenger system. Biochim Biophys Acta 1584: 73-80.
-
(2002)
Biochim Biophys Acta
, vol.1584
, pp. 73-80
-
-
Neri, L.M.1
Borgatti, P.2
Capitani, S.3
Martelli, A.M.4
-
22
-
-
0033056431
-
A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation
-
Niederberger C, Schweingruber ME. 1999. A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation. Mol Gen Genet 261:177-183.
-
(1999)
Mol Gen Genet
, vol.261
, pp. 177-183
-
-
Niederberger, C.1
Schweingruber, M.E.2
-
23
-
-
14544299215
-
Mechanisms of receptor-mediated nuclear import and nuclear export
-
Pemberton LF, Paschal BM. 2005. Mechanisms of receptor-mediated nuclear import and nuclear export. Traffic 6: 187-198.
-
(2005)
Traffic
, vol.6
, pp. 187-198
-
-
Pemberton, L.F.1
Paschal, B.M.2
-
24
-
-
14844357714
-
Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation
-
Scheid MP, Parsons M, Woodgett JR. 2005. Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. Mol Cell Biol 25:2347-2363.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2347-2363
-
-
Scheid, M.P.1
Parsons, M.2
Woodgett, J.R.3
-
25
-
-
0037086609
-
PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism
-
Tian X, Rusanescu G, Hou W, Schaffhausen B, Feig LA. 2002. PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism. Embo J 21:1327-1338.
-
(2002)
Embo J
, vol.21
, pp. 1327-1338
-
-
Tian, X.1
Rusanescu, G.2
Hou, W.3
Schaffhausen, B.4
Feig, L.A.5
-
26
-
-
0034757776
-
The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases
-
Volmat V, Camps M, Arkinstall S, Pouyssegur J, Lenormand P. 2001. The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases. J Cell Sci 114:3433-3443.
-
(2001)
J Cell Sci
, vol.114
, pp. 3433-3443
-
-
Volmat, V.1
Camps, M.2
Arkinstall, S.3
Pouyssegur, J.4
Lenormand, P.5
-
27
-
-
0035502498
-
A new molecular target of insulin action: Regulating the pivotal PDK1
-
Wick KL, Liu F. 2001. A new molecular target of insulin action: Regulating the pivotal PDK1. Curr Drug Targets Immune Endocr Metabol Disord 1:209-221.
-
(2001)
Curr Drug Targets Immune Endocr Metabol Disord
, vol.1
, pp. 209-221
-
-
Wick, K.L.1
Liu, F.2
-
28
-
-
0037053364
-
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide- dependent protein kinase-1 in cells
-
Wick MJ, Wick KR, Chen H, He H, Dong LQ, Quon MJ, Liu F. 2002. Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells. J Biol Chem 277:16632-16638.
-
(2002)
J Biol Chem
, vol.277
, pp. 16632-16638
-
-
Wick, M.J.1
Wick, K.R.2
Chen, H.3
He, H.4
Dong, L.Q.5
Quon, M.J.6
Liu, F.7
-
29
-
-
0242384929
-
Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop
-
Wick MJ, Ramos FJ, Chen H, Quon MJ, Dong LQ, Liu F. 2003. Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop. J Biol Chem 278:42913-42919.
-
(2003)
J Biol Chem
, vol.278
, pp. 42913-42919
-
-
Wick, M.J.1
Ramos, F.J.2
Chen, H.3
Quon, M.J.4
Dong, L.Q.5
Liu, F.6
-
30
-
-
0033637979
-
Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N
-
Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ, Blackshaw S, Ferris CD, Snyder SH. 2000. Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N. Cell 103:919-930.
-
(2000)
Cell
, vol.103
, pp. 919-930
-
-
Ye, K.1
Hurt, K.J.2
Wu, F.Y.3
Fang, M.4
Luo, H.R.5
Hong, J.J.6
Blackshaw, S.7
Ferris, C.D.8
Snyder, S.H.9
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