Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 22, 2002, Pages 14053-14058

  Donaldson, Logan W ^a,b,c   Gish, Gerald ^a,d   Pawson, Tony ^a,d   Kay, Lewis E ^a,b   Forman Kay, Julie D ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c YORK UNIVERSITY   (Canada)

^d MOUNT SINAI HOSPITAL   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Domain orientation; Modular binding domain; NMR; Signal transduction

Indexed keywords

ABELSON KINASE; ADAPTOR PROTEIN; PHOSPHOPEPTIDE; PHOSPHOTRANSFERASE; PHOSPHOTYROSINE; PROTEIN CRK; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME BINDING; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHOPEPTIDES; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-CRK; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SRC HOMOLOGY DOMAINS;

EID: 0037195067     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.212518799     Document Type: Article

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