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Volumn 18, Issue 3, 2000, Pages 293-302

Optimized production and purification of Bacillus anthracis lethal factor

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL SEQUENCE; CHROMATOGRAPHY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CULTURE MEDIUM; GENE MUTATION; HYBRID PROTEIN; METALLOPROTEINASE; PROMOTER REGION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; SHUTTLE VECTOR; SIGNAL PEPTIDE; VIRULENCE; WILD RELATIVE;

EID: 0034049623     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1006/prep.2000.1208     Document Type: Article
Times cited : (119)

References (36)
  • 1
    • 0000059216 scopus 로고
    • The chemical basis of the virulence of Bacillus anthracis. IX. Its aggressins and their mode of action
    • Keppie J., Harris-Smith P. W., Smith H. The chemical basis of the virulence of Bacillus anthracis. IX. Its aggressins and their mode of action. Br. J. Exp. Pathol. 44:1963;446-453.
    • (1963) Br. J. Exp. Pathol. , vol.44 , pp. 446-453
    • Keppie, J.1    Harris-Smith, P.W.2    Smith, H.3
  • 2
    • 0343747120 scopus 로고    scopus 로고
    • Anthrax
    • W. N. Kelley. Philadelphia: Lippincott-Raven
    • Friedlander A. M. Anthrax. Kelley W. N. Textbook of Internal Medicine. 1997;1508-1510 Lippincott-Raven, Philadelphia.
    • (1997) Textbook of Internal Medicine , pp. 1508-1510
    • Friedlander, A.M.1
  • 3
    • 0002107879 scopus 로고    scopus 로고
    • The bifactorial Bacillus anthracis lethal and oedema toxins
    • J. E. Alouf, & J. H. Freer. London: Academic Press
    • Leppla S. H. The bifactorial Bacillus anthracis lethal and oedema toxins. Alouf J. E., Freer J. H. Comprehensive Sourcebook of Bacterial Protein Toxins. 1999;243-263 Academic Press, London.
    • (1999) Comprehensive Sourcebook of Bacterial Protein Toxins , pp. 243-263
    • Leppla, S.H.1
  • 4
    • 0000947082 scopus 로고
    • Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
    • Leppla S. H. Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc. Natl. Acad. Sci. USA. 79:1982;3162-3166.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 3162-3166
    • Leppla, S.H.1
  • 6
    • 0032581369 scopus 로고    scopus 로고
    • Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
    • Vitale G., Pellizzari R., Recchi C., Napolitani G., Mock M., Montecucco C. Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochem. Biophys. Res. Commun. 248:1998;706-711.
    • (1998) Biochem. Biophys. Res. Commun. , vol.248 , pp. 706-711
    • Vitale, G.1    Pellizzari, R.2    Recchi, C.3    Napolitani, G.4    Mock, M.5    Montecucco, C.6
  • 8
    • 0028935459 scopus 로고
    • Protective immunity induced by Bacillus anthracis toxin-deficient strains
    • Pezard C., Weber M., Sirard J. C., Berche P., Mock M. Protective immunity induced by Bacillus anthracis toxin-deficient strains. Infect. Immun. 63:1995;1369-1372.
    • (1995) Infect. Immun. , vol.63 , pp. 1369-1372
    • Pezard, C.1    Weber, M.2    Sirard, J.C.3    Berche, P.4    Mock, M.5
  • 9
    • 0020826341 scopus 로고
    • Cloning of the protective antigen gene of Bacillus anthracis
    • Vodkin M. H., Leppla S. H. Cloning of the protective antigen gene of Bacillus anthracis. Cell. 34:1983;693-697.
    • (1983) Cell , vol.34 , pp. 693-697
    • Vodkin, M.H.1    Leppla, S.H.2
  • 10
    • 0022497188 scopus 로고
    • Molecular cloning and expression in Escherichia coli of the lethal factor gene of Bacillus anthracis
    • Robertson D. L., Leppla S. H. Molecular cloning and expression in Escherichia coli of the lethal factor gene of Bacillus anthracis. Gene. 44:1986;71-78.
    • (1986) Gene , vol.44 , pp. 71-78
    • Robertson, D.L.1    Leppla, S.H.2
  • 11
    • 0023947193 scopus 로고
    • Molecular cloning and expression of the Bacillus anthracis edema factor toxin gene: A calmodulin-dependent adenylate cyclase
    • Tippetts M. T., Robertson D. L. Molecular cloning and expression of the Bacillus anthracis edema factor toxin gene: A calmodulin-dependent adenylate cyclase. J. Bacteriol. 170:1988;2263-2266.
    • (1988) J. Bacteriol. , vol.170 , pp. 2263-2266
    • Tippetts, M.T.1    Robertson, D.L.2
  • 12
    • 0023758535 scopus 로고
    • Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis
    • Welkos S. L., Lowe J. R., Eden-McCutchan F., Vodkin M., Leppla S. H., Schmidt J. J. Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene. 69:1988;287-300.
    • (1988) Gene , vol.69 , pp. 287-300
    • Welkos, S.L.1    Lowe, J.R.2    Eden-McCutchan, F.3    Vodkin, M.4    Leppla, S.H.5    Schmidt, J.J.6
  • 13
    • 0024262750 scopus 로고
    • Structural homology between virulence-associated bacterial adenylate cyclases
    • Escuyer V., Duflot E., Sezer O., Danchin A., Mock M. Structural homology between virulence-associated bacterial adenylate cyclases. Gene. 71:1988;293-298.
    • (1988) Gene , vol.71 , pp. 293-298
    • Escuyer, V.1    Duflot, E.2    Sezer, O.3    Danchin, A.4    Mock, M.5
  • 14
    • 0024234807 scopus 로고
    • Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): A calmodulin-dependent adenylate cyclase
    • Robertson D. L., Tippetts M. T., Leppla S. H. Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): A calmodulin-dependent adenylate cyclase. Gene. 73:1988;363-371.
    • (1988) Gene , vol.73 , pp. 363-371
    • Robertson, D.L.1    Tippetts, M.T.2    Leppla, S.H.3
  • 15
    • 0024467357 scopus 로고
    • Nucleotide sequence and analysis of the lethal factor gene (lef) from Bacillus anthracis
    • Bragg T. S., Robertson D. L. Nucleotide sequence and analysis of the lethal factor gene (lef) from Bacillus anthracis. Gene. 81:1989;45-54.
    • (1989) Gene , vol.81 , pp. 45-54
    • Bragg, T.S.1    Robertson, D.L.2
  • 16
    • 84925231914 scopus 로고
    • Immunity to anthrax. Protective antigen present in cell-free culture filtrates
    • Gladstone G. P. Immunity to anthrax. Protective antigen present in cell-free culture filtrates. Br. J. Exp. Pathol. 27:1946;349-418.
    • (1946) Br. J. Exp. Pathol. , vol.27 , pp. 349-418
    • Gladstone, G.P.1
  • 17
    • 0024316501 scopus 로고
    • Transcriptional regulation of the protective antigen gene of Bacillus anthracis
    • Bartkus J. M., Leppla S. H. Transcriptional regulation of the protective antigen gene of Bacillus anthracis. Infect. Immun. 57:1989;2295-2300.
    • (1989) Infect. Immun. , vol.57 , pp. 2295-2300
    • Bartkus, J.M.1    Leppla, S.H.2
  • 18
    • 0027247956 scopus 로고
    • Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis
    • Uchida I., Hornung J. M., Thorne C. B., Klimpel K. R., Leppla S. H. Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis. J. Bacteriol. 175:1993;5329-5338.
    • (1993) J. Bacteriol. , vol.175 , pp. 5329-5338
    • Uchida, I.1    Hornung, J.M.2    Thorne, C.B.3    Klimpel, K.R.4    Leppla, S.H.5
  • 19
    • 0028157366 scopus 로고
    • Regulation of the Bacillus anthracis protective antigen gene: CO2 and a trans-acting element activate transcription from one of two promoters
    • Koehler T. M., Dai Z., Kaufman-Yarbray M. Regulation of the Bacillus anthracis protective antigen gene: CO2 and a trans-acting element activate transcription from one of two promoters. J. Bacteriol. 176:1994;586-595.
    • (1994) J. Bacteriol. , vol.176 , pp. 586-595
    • Koehler, T.M.1    Dai, Z.2    Kaufman-Yarbray, M.3
  • 20
    • 0029162545 scopus 로고
    • The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence
    • Dai Z., Sirard J. C., Mock M., Koehler T. M. The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence. Mol. Microbiol. 16:1995;1171-1181.
    • (1995) Mol. Microbiol. , vol.16 , pp. 1171-1181
    • Dai, Z.1    Sirard, J.C.2    Mock, M.3    Koehler, T.M.4
  • 22
    • 0000941241 scopus 로고
    • Large-scale production of protective antigen of Bacillus anthracis in anaerobic cultures
    • Puziss M., Manning L. C., Lynch J. W., Barclay E., Abelow I., Wright G. G. Large-scale production of protective antigen of Bacillus anthracis in anaerobic cultures. Appl. Microbiol. 11:1963;330-334.
    • (1963) Appl. Microbiol. , vol.11 , pp. 330-334
    • Puziss, M.1    Manning, L.C.2    Lynch, J.W.3    Barclay, E.4    Abelow, I.5    Wright, G.G.6
  • 23
    • 0025854680 scopus 로고
    • Purification and characterization of adenylyl cyclase from Bacillus anthracis
    • R. A. Johnson, & J. D. Corbin. San Diego: Academic Press
    • Leppla S. H. Purification and characterization of adenylyl cyclase from Bacillus anthracis. Johnson R. A., Corbin J. D. Methods in Enzymology. 1991;153-168 Academic Press, San Diego.
    • (1991) Methods in Enzymology , pp. 153-168
    • Leppla, S.H.1
  • 24
    • 0024214705 scopus 로고
    • Production and purification of anthrax toxin
    • S. Harshman. Orlando: Academic Press
    • Leppla S. H. Production and purification of anthrax toxin. Harshman S. Methods in Enzymology. 1988;103-116 Academic Press, Orlando.
    • (1988) Methods in Enzymology , pp. 103-116
    • Leppla, S.H.1
  • 25
    • 0001256478 scopus 로고    scopus 로고
    • Anthrax toxin
    • K. Aktories, & I. Just. Berlin: Springer
    • Leppla S. H. Anthrax toxin. Aktories K., Just I. Bacterial Protein Toxins. 2000;Springer, Berlin.
    • (2000) Bacterial Protein Toxins
    • Leppla, S.H.1
  • 27
    • 0024837128 scopus 로고
    • A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
    • Singh Y., Chaudhary V. K., Leppla S. H. A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J. Biol. Chem. 264:1989;19103-19107.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19103-19107
    • Singh, Y.1    Chaudhary, V.K.2    Leppla, S.H.3
  • 29
    • 0025345676 scopus 로고
    • Transformation of vegetative cells of Bacillus anthracis with plasmid DNA
    • Quinn C. P., Dancer B. N. Transformation of vegetative cells of Bacillus anthracis with plasmid DNA. J. Gen. Microbiol. 136:1990;1211-1215.
    • (1990) J. Gen. Microbiol. , vol.136 , pp. 1211-1215
    • Quinn, C.P.1    Dancer, B.N.2
  • 30
    • 0013797229 scopus 로고
    • Immunochemical quantitation of antigens by single radial immunodiffusion
    • Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 2:1965;235-254.
    • (1965) Immunochemistry , vol.2 , pp. 235-254
    • Mancini, G.1    Carbonara, A.O.2    Heremans, J.F.3
  • 31
    • 0031925706 scopus 로고    scopus 로고
    • Internalization of a Bacillus anthracis protective antigen c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies
    • Varughese M., Chi A., Teixeira A. V., Nicholls P. J., Keith J. M., Leppla S. H. Internalization of a Bacillus anthracis protective antigen c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies. Mol. Med. 4:1998;87-95.
    • (1998) Mol. Med. , vol.4 , pp. 87-95
    • Varughese, M.1    Chi, A.2    Teixeira, A.V.3    Nicholls, P.J.4    Keith, J.M.5    Leppla, S.H.6
  • 32
    • 0028088404 scopus 로고
    • Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
    • Klimpel K. R., Arora N., Leppla S. H. Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol. Microbiol. 13:1994;1093-1100.
    • (1994) Mol. Microbiol. , vol.13 , pp. 1093-1100
    • Klimpel, K.R.1    Arora, N.2    Leppla, S.H.3
  • 33
    • 0023022205 scopus 로고
    • Cloning and expression of the Bacillus anthracis protective antigen gene in Bacillus subtilis
    • Ivins B. E., Welkos S. L. Cloning and expression of the Bacillus anthracis protective antigen gene in Bacillus subtilis. Infect. Immun. 54:1986;537-542.
    • (1986) Infect. Immun. , vol.54 , pp. 537-542
    • Ivins, B.E.1    Welkos, S.L.2
  • 34
    • 0028873388 scopus 로고
    • The transformation frequency of plasmids into Bacillus anthracis is affected by adenine methylation
    • Marrero R., Welkos S. L. The transformation frequency of plasmids into Bacillus anthracis is affected by adenine methylation. Gene. 152:1995;75-78.
    • (1995) Gene , vol.152 , pp. 75-78
    • Marrero, R.1    Welkos, S.L.2
  • 35
    • 0344457370 scopus 로고    scopus 로고
    • Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli
    • Bron S., Bolhuis A., Tjalsma H., Holsappel S., Venema G., van Dijl J. M. Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli. J. Biotechnol. 64:1998;3-13.
    • (1998) J. Biotechnol. , vol.64 , pp. 3-13
    • Bron, S.1    Bolhuis, A.2    Tjalsma, H.3    Holsappel, S.4    Venema, G.5    Van Dijl, J.M.6
  • 36
    • 0030868265 scopus 로고    scopus 로고
    • Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes
    • Tjalsma H., Noback M. A., Bron S., Venema G., Yamane K., van Dijl J. M. Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes. J. Biol. Chem. 272:1997;25983-25992.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25983-25992
    • Tjalsma, H.1    Noback, M.A.2    Bron, S.3    Venema, G.4    Yamane, K.5    Van Dijl, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.