Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin

Cellular Microbiology

Volumn 7, Issue 2, 2005, Pages 281-292

  Kassam, Altaf ^a   Der, Sandy D ^a   Mogridge, Jeremy ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; DNA FRAGMENT; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SYNAPTOPHYSIN;

ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CHROMOSOME CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; HOST RESISTANCE; HOST SUSCEPTIBILITY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

AMINO ACID CHLOROMETHYL KETONES; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CYSTEINE PROTEINASE INHIBITORS; DNA; DNA FRAGMENTATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUMOR NECROSIS FACTOR-ALPHA;

ANTHRAX; BACILLUS ANTHRACIS; MAMMALIA;

EID: 13844318262     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2004.00458.x     Document Type: Article

References (60)

1. Abraham, M.C., and Shaham, S. (2004) Death without caspases, caspases without death. Trends Cell Biol 14: 184-193.
2. Aderem, A., and Ulevitch, R.J. (2000) Toll-like receptors in the induction of the innate immune response. Nature 406: 782-787.
3. Aihara, H., Asaoka, Y., Yoshida, K., and Nishizuka, Y. (1991) Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage. Proc Natl Acad Sci USA 88: 11062-11066.
4. Blanke, S.R., Milne, J.C., Benson, E.L., and Collier, R.J. (1996) Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen. Proc Natl Acad Sci USA 93: 8437-8442.
5. Bradley, K.A., Mogridge, J., Mourez, M., Collier, R.J., and Young, J.A. (2001) Identification of the cellular receptor for anthrax toxin. Nature 414: 225-229.
6. Bustin, S.A. (2000) Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 25: 169-193.
7. Calandra, T., and Roger, T. (2003) Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 3: 791-800.
8. Carson-Walter, E.B., Watkins, D.N., Nanda, A., Vogelstein, B., Kinzler, K.W., and St Croix, B. (2001) Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Res 61: 6649-6655.
9. Cohen, P. (1999) The development and therapeutic potential of protein kinase inhibitors. Curr Opin Chem Biol 3: 459-465.
10. Collier, R.J., and Young, J.A. (2003) Anthrax toxin. Annu Rev Cell Dev Biol 19: 45-70.
11. Collins, S.J. (1987) The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 70: 1233-1244.
12. Cui, X., Moayeri, M., Li, Y., Li, X., Haley, M., Fitz, Y., et al. (2004) Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats. Am J Physiol Regul Integr Comp Physiol 286: R699-R709.
13. Das, D., Pintucci, G., and Stern, A. (2000) MAPK-dependent expression of p21 (WAF) and p27 (kip1) in PMA-induced differentiation of HL60 cells. FEBS Lett 472: 50-52.
14. Dixon, T.C., Fadl, A.A., Koehler, T.M., Swanson, J.A., and Hanna, P.C. (2000) Early Bacillus anthracis-macrophage interactions: intracellular survival survival and escape. Cell Microbiol 2: 453-463.
15. Dudley, D.T., Pang, L., Decker, S.J., Bridges, A.J., and Saltiel, A.R. (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92: 7686-7689.
16. Duesbery, N.S., Webb, C.P., Leppla, S.H., Gordon, V.M., Klimpel, K.R., Copeland, T.D., et al. (1998) Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 280: 734-737.
17. English, J., Pearson, G., Wilsbacher, J., Swantek, J., Karandikar, M., Xu, S., and Cobb, M.H. (1999) New insights into the control of MAP kinase pathways. Exp Cell Res 253: 255-270.
18. Ferraro, C., Quemeneur, L., Fournel, S., Prigent, A.F., Revillard, J.P., and Bonnefoy-Berard, N. (2000) The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes. Cell Death Differ 7: 197-206.
19. Friedlander, A.M. (1986) Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem 261: 7123-7126.
20. Gibson, U.E., Heid, C.A., and Williams, P.M. (1996) A novel method for real time quantitative RT-PCR. Genome Res 6: 995-1001.
21. Guidi-Rontani, C., Levy, M., Ohayon, H., and Mock, M. (2001) Fate of germinated Bacillus anthracis spores in primary murine macrophages. Mol Microbiol 42: 931-938.
22. Hanna, P.C., and Ireland, J.A. (1999) Understanding Bacillus anthracis pathogenesis. Trends Microbiol 7: 180-182.
23. Hanna, P.C., Acosta, D., and Collier, R.J. (1993) On the role of macrophages in anthrax. Proc Natl Acad Sci USA 90: 10198-10201.
24. Higuchi, R., Fockler, C., Dollinger, G., and Watson, R. (1993) Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (NY) 11: 1026-1030.
25. Janeway, C.A., Jr, and Medzhitov, R. (2002) Innate immune recognition. Annu Rev Immunol 20: 197-216.
26. Jernigan, J.A., Stephens, D.S., Ashford, D.A., Omenaca, C., Topiel, M.S., Galbraith, M., et al. (2001) Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United States. Emerg Infect Dis 7: 933-944.
27. Johnson, G.L., and Lapadat, R. (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912.
28. Kim, S.O., Jing, Q., Hoebe, K., Beutler, B., Duesbery, N.S., and Han, J. (2003) Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J Biol Chem 278: 7413-7421.
29. King, M.A., and Radicchi-Mastroianni, M.A. (2002) Effects of caspase inhibition on camptothecin-induced apoptosis of HL-60 cells. Cytometry 49: 28-35.
30. King, M.A,, Radicchi-Mastroianni, M.A., and Wells, J.V. (2000) There is substantial nuclear and cellular disintegration before detectable phosphatidylserine exposure during the camptothecin-induced apoptosis of HL-60 cells. Cytometry 40: 10-18.
31. Kirby, J.E. (2004) Anthrax lethal toxin induces human endothelial cell apoptosis. Infect Immun 72: 430-439.
32. Koo, H.M., VanBrocklin, M., McWilliams, M.J., Leppla, S.H., Duesbery, N.S., and Woude, G.F. (2002) Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proc Natl Acad Sci USA 99: 3052-3057.
33. Lee, S.B., and Esteban, M. (1994) The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199: 491-496.
34. Leppla, S.H. (1982) Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci USA 79: 3162-3166.
35. Li, C., Wang, Y., Gao, L., Zhang, J., Shao, J., Wang, S., et al. (2002) Expression of toll-like receptors 2 and 4 and CD14 during differentiation of HL-60 cells induced by phorbol 12-myristate 13-acetate and 1 alpha, 25-dihydroxy-vitamin D (3). Cell Growth Differ 13: 27-38.
36. Lin, C.G., Kao, Y.T., Liu, W.T., Huang, H.H., Chen, K.C., Wang, T.M., and Lin, H.C. (1996) Cytotoxic effects of anthrax lethal toxin on macrophage-like cell line J774A.1. Curr Microbiol 33: 224-227.
37. McGahon, A.J., Martin, S.J., Bissonnette, R.P., Mahboubi, A., Shi, Y., Mogil, R.J., et al. (1995) The end of the (cell) line: methods for the study of apoptosis in vitro. Methods Cell Biol 46: 153-185.
38. Matthews, N., and Neale, M.L. (1987) Lymphokines and Interferons: A Practical Approach. Oxford: IRL Press.
39. Medzhitov, R., and Janeway, C.A., Jr (1997) Innate immunity: impact on the adaptive immune response. Curr Opin Immunol 9: 4-9.
40. Menaker, R.J., Ceponis, P.J., and Jones, N.L. (2004) Helicobacter pylori induces apoptosis of macrophages in association with alterations in the mitochondrial pathway. Infect Immun 72: 2889-2898.
41. Miller, C.J., Elliott, J.L., and Collier, R.J. (1999) Anthrax protective antigen: prepore-to-pore conversion. Biochemistry 38: 10432-10441.
42. Milne, J.C., Blanke, S.R., Hanna, P.C., and Collier, R.J. (1995) Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus. Mol Microbiol 15: 661-666.
43. Miranda, M.B., McGuire, T.F., and Johnson, D.E. (2002) Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines. Leukemia 16: 683-692.
44. Moayeri, M., Haines, D., Young, H.A., and Leppla, S.H. (2003) Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice. J Clin Invest 112: 670-682.
45. Navarre, W.W., and Zychlinsky, A. (2000) Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies. Cell Microbiol 2: 265-273.
46. O'Brien, J., Friedlander, A., Dreier, T., Ezzell, J., and Leppla, S. (1985) Effects of anthrax toxin components on human neutrophils. Infect Immun 47: 306-310.
47. Park, J.M., Greten, F.R., Li, Z.W., and Karin, M. (2002) Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297: 2048-2051.
48. Pellizzari, R., Guidi-Rontani, C., Vitale, G., Mock, M., and Montecucco, C. (1999) Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett 462: 199-204.
49. Roussel, M.F. (1998) Key effectors of signal transduction and G1 progression. Adv Cancer Res 74: 1-24.
50. Rovera, G., Santoli, D., and Damsky, C. (1979) Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. Proc Natl Acad Sci USA 76: 2779-2783.
51. Ruthel, G., Ribot, W.J., Bavari, S., and Hoover, T.A. (2004) Time-lapse confocal imaging of development of Bacillus anthracis in macrophages. J Infect Dis 189: 1313-1316.
52. Salles, I.I., Tucker, A.E., Voth, D.E., and Ballard, J.D. (2003) Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Acad Sci USA 100: 12426-12431.
53. Schultz, H., Engel, K., and Gaestel, M. (1997) PMA-induced activation of the p42/44ERK- and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J Cell Physiol 173: 310-318.
54. Scobie, H.M., Rainey, G.J., Bradley, K.A., and Young, J.A. (2003) Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci USA 100: 5170-5174.
55. Tucker, A.E., Salles, I.I., Voth, D.E., Ortiz-Leduc, W., Wang, H., Dozmorov, I., et al. (2003) Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages. Cell Microbiol 5: 523-532.
56. Vitale, G., Pellizzari, R., Recchi, C., Napolitani, G., Mock, M., and Montecucco, C. (1998) Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochem Biophys Res Commun 248: 706-711.
57. Vitale, G., Bernardi, L., Napolitani, G., Mock, M., and Montecucco, C. (2000) Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem J 352: 739-745.
58. Wang, X., and Studzinski, G.P. (2001) Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells. J Cell Biochem 82: 68-77.
59. Watters, J.W., Dewar, K., Lehoczky, J., Boyartchuk, V., and Dietrich, W.F. (2001) Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor. Curr Biol 11: 1503-1511.
60. Wesche, J., Elliott, J.L., Falnes, P.O., Olsnes, S., and Collier, R.J. (1998) Characterization of membrane translocation by anthrax protective antigen. Biochemistry 37: 15737-15746.