메뉴 건너뛰기




Volumn 152, Issue 8, 2007, Pages 1147-1154

Novel approaches to developing new antibiotics for bacterial infections

Author keywords

Antibiotic resistance; Bacterial infections; Bacteriophages; Genomics; Multiplying bacteria; Non culturable bacteria; Non multiplying bacteria; Novel antibiotics

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; CLAVULANIC ACID; ISONIAZID; METRONIDAZOLE; OXAZOLIDINONE DERIVATIVE; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULFAMIDOCHRYSOIDINE;

EID: 36949030717     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707432     Document Type: Review
Times cited : (174)

References (113)
  • 1
    • 84910769907 scopus 로고
    • Cephalosporins 1945-86
    • Williams, JD ed, Adis Press: Auckland. pp
    • Abraham EP (1987). Cephalosporins 1945-86. In: Williams, JD (ed). The Cephalosporins. Adis Press: Auckland. pp 1-14.
    • (1987) The Cephalosporins , pp. 1-14
    • Abraham, E.P.1
  • 2
    • 0033864824 scopus 로고    scopus 로고
    • Infective endocarditis: A diagnostic and therapeutic challenge for the new millennium
    • Alestig K, Hogevik H, Olaison L (2000). Infective endocarditis: a diagnostic and therapeutic challenge for the new millennium. Scand J Infect Dis 32: 343-356.
    • (2000) Scand J Infect Dis , vol.32 , pp. 343-356
    • Alestig, K.1    Hogevik, H.2    Olaison, L.3
  • 4
    • 32444434918 scopus 로고    scopus 로고
    • The potential impact of structural genomics on tuberculosis drug discovery
    • Arcus VL, Lott JS, Johnston JM, Baker EN (2006). The potential impact of structural genomics on tuberculosis drug discovery. Drug Discov Today 11: 28-34.
    • (2006) Drug Discov Today , vol.11 , pp. 28-34
    • Arcus, V.L.1    Lott, J.S.2    Johnston, J.M.3    Baker, E.N.4
  • 7
    • 0038587681 scopus 로고    scopus 로고
    • Structure-activity relationships leading to linezolid
    • Barbachyn MR, Ford CW (2003). Structure-activity relationships leading to linezolid. Angew Chem Int Ed Engl 42: 2010-2023.
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 2010-2023
    • Barbachyn, M.R.1    Ford, C.W.2
  • 8
    • 0032720205 scopus 로고    scopus 로고
    • Response of the pharmaceutical industry to antimicrobial resistance
    • Bax RP, Mullan N (1999). Response of the pharmaceutical industry to antimicrobial resistance. Balliere Clin Infect Dis 5: 289-304.
    • (1999) Balliere Clin Infect Dis , vol.5 , pp. 289-304
    • Bax, R.P.1    Mullan, N.2
  • 10
    • 33645030241 scopus 로고    scopus 로고
    • Robust Salmonella metabolism limits possibilities for new antimicrobials
    • Becker D, Selbach M, Rollenhagen C, Ballmaier M, Meyer TF, Mann M et al. (2006). Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature 440: 303-307.
    • (2006) Nature , vol.440 , pp. 303-307
    • Becker, D.1    Selbach, M.2    Rollenhagen, C.3    Ballmaier, M.4    Meyer, T.F.5    Mann, M.6
  • 12
    • 0035933529 scopus 로고    scopus 로고
    • A protein antibiotic in the phage Qbeta virion: Diversity in lysis targets
    • Bernhardt TG, Wang IN, Struck DK, Young R (2001). A protein antibiotic in the phage Qbeta virion: diversity in lysis targets. Science 292: 2326-2329.
    • (2001) Science , vol.292 , pp. 2326-2329
    • Bernhardt, T.G.1    Wang, I.N.2    Struck, D.K.3    Young, R.4
  • 13
    • 22144455317 scopus 로고    scopus 로고
    • Novel target sites in bacteria for overcoming antibiotic resistance
    • Black MT, Hodgson J (2005). Novel target sites in bacteria for overcoming antibiotic resistance. Adv Drug Deliv Rev 57: 1528-1538.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1528-1538
    • Black, M.T.1    Hodgson, J.2
  • 14
    • 33645227952 scopus 로고    scopus 로고
    • Bacteriophage endolysins as a novel class of antibacterial agents
    • Borysowski J, Weber-Dabrowska B, Gorski A (2006). Bacteriophage endolysins as a novel class of antibacterial agents. Exp Biol Med (Maywood) 231: 366-377.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 366-377
    • Borysowski, J.1    Weber-Dabrowska, B.2    Gorski, A.3
  • 16
    • 33745090237 scopus 로고    scopus 로고
    • Phospho-MurNAc-pentapeptide translocase (MraY) as a target for antibacterial agents and antibacterial proteins
    • Bugg TD, Lloyd AJ, Roper DI (2006). Phospho-MurNAc-pentapeptide translocase (MraY) as a target for antibacterial agents and antibacterial proteins. Infect Disord Drug Targets 6: 85-106.
    • (2006) Infect Disord Drug Targets , vol.6 , pp. 85-106
    • Bugg, T.D.1    Lloyd, A.J.2    Roper, D.I.3
  • 17
    • 0011491051 scopus 로고    scopus 로고
    • Peptide deformylase inhibitors, potential for a new class of broad spectrum antibacterials
    • Clements JM, Ayscough A, Keavey K, East SP (2002). Peptide deformylase inhibitors, potential for a new class of broad spectrum antibacterials. Curr Med Chem 1: 239-249.
    • (2002) Curr Med Chem , vol.1 , pp. 239-249
    • Clements, J.M.1    Ayscough, A.2    Keavey, K.3    East, S.P.4
  • 18
    • 33745112148 scopus 로고    scopus 로고
    • New strategies for antibacterial drug design: Targeting non-multiplying latent bacteria
    • Coates AR, Hu Y (2006). New strategies for antibacterial drug design: targeting non-multiplying latent bacteria. Drugs R D 7: 133-151.
    • (2006) Drugs R D , vol.7 , pp. 133-151
    • Coates, A.R.1    Hu, Y.2
  • 19
    • 0036834373 scopus 로고    scopus 로고
    • The future challenges facing the development of new antimicrobial drugs
    • Coates A, Hu Y, Bax R, Page C (2002). The future challenges facing the development of new antimicrobial drugs. Nat Rev Drug Discov 1: 895-910.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 895-910
    • Coates, A.1    Hu, Y.2    Bax, R.3    Page, C.4
  • 20
    • 11144238288 scopus 로고    scopus 로고
    • Resistance trends in Streptococcus pyogenes (PROTEKT years 1-3 [1999-2002])
    • Cohen R, Green M (2004). Resistance trends in Streptococcus pyogenes (PROTEKT years 1-3 [1999-2002]). J Chemother 6: 71-82.
    • (2004) J Chemother , vol.6 , pp. 71-82
    • Cohen, R.1    Green, M.2
  • 21
    • 0033591467 scopus 로고    scopus 로고
    • Bacterial biofilms: A common cause of persistent infections
    • Costerton JW, Stewart PS, Greenberg EP (1999). Bacterial biofilms: a common cause of persistent infections. Science 284: 1318-1322.
    • (1999) Science , vol.284 , pp. 1318-1322
    • Costerton, J.W.1    Stewart, P.S.2    Greenberg, E.P.3
  • 22
    • 23044482239 scopus 로고    scopus 로고
    • Preincubation of pneumococci with beta-lactams alone or combined with levofloxacin prevents quinolone-induced resistance without increasing intracellular levels of levofloxacin
    • Cottagnoud P, Johnson M, Cottagnoud M, Piddock L (2005). Preincubation of pneumococci with beta-lactams alone or combined with levofloxacin prevents quinolone-induced resistance without increasing intracellular levels of levofloxacin. Antimicrob Agents Chemother 49: 3517-3519.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3517-3519
    • Cottagnoud, P.1    Johnson, M.2    Cottagnoud, M.3    Piddock, L.4
  • 23
    • 0027751617 scopus 로고
    • Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria
    • Craig M, McCready TL, Luu HA, Smillie MA, Dubord P, Holmes CF (1993). Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria. Toxicon 31: 1541-1549.
    • (1993) Toxicon , vol.31 , pp. 1541-1549
    • Craig, M.1    McCready, T.L.2    Luu, H.A.3    Smillie, M.A.4    Dubord, P.5    Holmes, C.F.6
  • 25
    • 0035136786 scopus 로고    scopus 로고
    • Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy
    • Dagan R, Klugman KP, Craig WA, Baquero F (2001). Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy. J Antimicrob Chemother 47: 129-140.
    • (2001) J Antimicrob Chemother , vol.47 , pp. 129-140
    • Dagan, R.1    Klugman, K.P.2    Craig, W.A.3    Baquero, F.4
  • 26
    • 33646244246 scopus 로고    scopus 로고
    • Determining the antibiotic resistance potential of the indigenous oralmicrobiota of humans using a metagenomic approach
    • Diaz-Torres ML, Villedieu A, Hunt N, McNab R, Spratt DA, Allan E et al. (2006). Determining the antibiotic resistance potential of the indigenous oralmicrobiota of humans using a metagenomic approach. FEMS Microbiol Lett 258: 257-262.
    • (2006) FEMS Microbiol Lett , vol.258 , pp. 257-262
    • Diaz-Torres, M.L.1    Villedieu, A.2    Hunt, N.3    McNab, R.4    Spratt, D.A.5    Allan, E.6
  • 27
    • 33744973283 scopus 로고    scopus 로고
    • Microbial genomics and drug discovery: Exploring innovative routes of drug discovery in the postgenomic era
    • Dougherty TJ, Miller PF (2006). Microbial genomics and drug discovery: exploring innovative routes of drug discovery in the postgenomic era. IDrugs 9: 420-422.
    • (2006) IDrugs , vol.9 , pp. 420-422
    • Dougherty, T.J.1    Miller, P.F.2
  • 28
    • 4344584222 scopus 로고    scopus 로고
    • Genomics-based approaches to novel antimicrobial target discovery
    • Dougherty TJ, Projan SJ eds, Marcel Dekker: New York. pp
    • Dougherty TJ, Barrett JF, Pucci MJ (2003). Genomics-based approaches to novel antimicrobial target discovery. In: Dougherty TJ, Projan SJ (eds). Microbial Genomics and Drug Discovery. Marcel Dekker: New York. pp 71-96.
    • (2003) Microbial Genomics and Drug Discovery , pp. 71-96
    • Dougherty, T.J.1    Barrett, J.F.2    Pucci, M.J.3
  • 29
    • 33745521230 scopus 로고    scopus 로고
    • Reducing the carriage of foodborne pathogens in livestock and poultry
    • Doyle MP, Erickson MC (2006). Reducing the carriage of foodborne pathogens in livestock and poultry. Poult Sci 85: 960-973.
    • (2006) Poult Sci , vol.85 , pp. 960-973
    • Doyle, M.P.1    Erickson, M.C.2
  • 30
    • 12344312184 scopus 로고    scopus 로고
    • Elliott TS, Foweraker J, Gould FK, Perry JD, Sandoe JA, Working Party of the British Society for Antimicrobial Chemotherapy (2004). Guidelines for the antibiotic treatment of endocarditis in adults: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother 54: 971-981.
    • Elliott TS, Foweraker J, Gould FK, Perry JD, Sandoe JA, Working Party of the British Society for Antimicrobial Chemotherapy (2004). Guidelines for the antibiotic treatment of endocarditis in adults: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother 54: 971-981.
  • 32
    • 4644271699 scopus 로고    scopus 로고
    • The changing face of antibiotic prescribing: The mutant selection window
    • Epstein BJ, Gums JG, Drlica K (2004). The changing face of antibiotic prescribing: the mutant selection window. Ann Pharmacother 38: 1675-1682.
    • (2004) Ann Pharmacother , vol.38 , pp. 1675-1682
    • Epstein, B.J.1    Gums, J.G.2    Drlica, K.3
  • 33
    • 33845719937 scopus 로고    scopus 로고
    • Antibacterial discovery and development-the failure of success?
    • Fernandez P (2006). Antibacterial discovery and development-the failure of success? Nat Biotechnol 24: 1497-1503.
    • (2006) Nat Biotechnol , vol.24 , pp. 1497-1503
    • Fernandez, P.1
  • 34
    • 3242887518 scopus 로고    scopus 로고
    • Using the genome to understand pathogenicity
    • Field D, Hughes J, Moxon ER (2004). Using the genome to understand pathogenicity. Methods Mol Biol 266: 261-287.
    • (2004) Methods Mol Biol , vol.266 , pp. 261-287
    • Field, D.1    Hughes, J.2    Moxon, E.R.3
  • 35
    • 33750737310 scopus 로고    scopus 로고
    • Gram-positive infections: Lessons learnt and novel solutions
    • Finch R (2006). Gram-positive infections: lessons learnt and novel solutions. Clin Microbiol Infect 12 (Suppl 8): 3-8.
    • (2006) Clin Microbiol Infect , vol.12 , Issue.SUPPL. 8 , pp. 3-8
    • Finch, R.1
  • 36
    • 33845361477 scopus 로고    scopus 로고
    • Testing the mutant selection window hypothesis with Staphylococcus aureus exposed to daptomycin and vancomycin in an in vitro dynamic model
    • Firsov AA, Smirnova MV, Lubenko IY, Vostrov SN, Portnoy YA, Zinner SH (2006). Testing the mutant selection window hypothesis with Staphylococcus aureus exposed to daptomycin and vancomycin in an in vitro dynamic model. J Antimicrob Chemother 58: 1185-1192.
    • (2006) J Antimicrob Chemother , vol.58 , pp. 1185-1192
    • Firsov, A.A.1    Smirnova, M.V.2    Lubenko, I.Y.3    Vostrov, S.N.4    Portnoy, Y.A.5    Zinner, S.H.6
  • 37
    • 33845688395 scopus 로고    scopus 로고
    • Reinventing phage therapy: Are the parts greater than the sum?
    • Fischetti VA, Nelson D, Schuch R (2006). Reinventing phage therapy: are the parts greater than the sum? Nat Biotechnol 24: 1508-1511.
    • (2006) Nat Biotechnol , vol.24 , pp. 1508-1511
    • Fischetti, V.A.1    Nelson, D.2    Schuch, R.3
  • 39
    • 0000378637 scopus 로고
    • On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae
    • Fleming A (1929). On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. Br J Exp Pathol 10: 226.
    • (1929) Br J Exp Pathol , vol.10 , pp. 226
    • Fleming, A.1
  • 41
    • 33144490023 scopus 로고    scopus 로고
    • Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, Poirel L et al. (2006). Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet 2: e7.
    • Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, Poirel L et al. (2006). Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet 2: e7.
  • 42
    • 33845706771 scopus 로고    scopus 로고
    • The business of developing antibacterials
    • Fox JL (2006). The business of developing antibacterials. Nat Biotechnol 24: 1521-1528.
    • (2006) Nat Biotechnol , vol.24 , pp. 1521-1528
    • Fox, J.L.1
  • 43
    • 21544464022 scopus 로고    scopus 로고
    • Functional genomics in antibacterial drug discovery
    • Freiberg C, Brotz-Oesterhelt H (2005). Functional genomics in antibacterial drug discovery. Drug Discov Today 10: 927-935.
    • (2005) Drug Discov Today , vol.10 , pp. 927-935
    • Freiberg, C.1    Brotz-Oesterhelt, H.2
  • 46
    • 33749858537 scopus 로고    scopus 로고
    • Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities
    • Garcia MH, Ivanova N, Kunin V, Warnecke F, Barry KW, McHardy AC et al. (2006). Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities. Nat Biotechnol 24: 1263-1269.
    • (2006) Nat Biotechnol , vol.24 , pp. 1263-1269
    • Garcia, M.H.1    Ivanova, N.2    Kunin, V.3    Warnecke, F.4    Barry, K.W.5    McHardy, A.C.6
  • 47
    • 0032481410 scopus 로고    scopus 로고
    • Low dosage and long treatment duration of beta-lactam: Risk factors for carriage of penicillin-resistant Streptococcus pneumoniae
    • Guillemot D, Carbon C, Balkau B, Geslin P, Lecoeur H, Vauzelle-Kervroedan F et al. (1998). Low dosage and long treatment duration of beta-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae. JAMA 279: 365-370.
    • (1998) JAMA , vol.279 , pp. 365-370
    • Guillemot, D.1    Carbon, C.2    Balkau, B.3    Geslin, P.4    Lecoeur, H.5    Vauzelle-Kervroedan, F.6
  • 49
    • 0036259508 scopus 로고    scopus 로고
    • Haney SA, Alkane LE, Dunman PM, Murphy E, Projan SJ (2002). Genomics in anti-infective drug discovery-getting to endgame. Curr Pharmaceut Des 8: 1099-1118.
    • Haney SA, Alkane LE, Dunman PM, Murphy E, Projan SJ (2002). Genomics in anti-infective drug discovery-getting to endgame. Curr Pharmaceut Des 8: 1099-1118.
  • 50
    • 0036597231 scopus 로고    scopus 로고
    • Bacteriophages: Evolution of the majority
    • Hendrix RW (2002). Bacteriophages: evolution of the majority. Theor Popul Biol 61: 471-480.
    • (2002) Theor Popul Biol , vol.61 , pp. 471-480
    • Hendrix, R.W.1
  • 51
    • 0031912339 scopus 로고    scopus 로고
    • Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock
    • Hu YM, Butcher PD, Sole K, Mitchison DA, Coates AR (1998). Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock. FEMS Microbiol Lett 158: 139-145.
    • (1998) FEMS Microbiol Lett , vol.158 , pp. 139-145
    • Hu, Y.M.1    Butcher, P.D.2    Sole, K.3    Mitchison, D.A.4    Coates, A.R.5
  • 52
    • 0032954835 scopus 로고    scopus 로고
    • Transcription of two sigma 70 homologue genes, sigA and sigB, in stationary-phase Mycobacterium tuberculosis
    • Hu Y, Coates AR (1999). Transcription of two sigma 70 homologue genes, sigA and sigB, in stationary-phase Mycobacterium tuberculosis. J Bacteriol 181: 469-476.
    • (1999) J Bacteriol , vol.181 , pp. 469-476
    • Hu, Y.1    Coates, A.R.2
  • 53
    • 0037311481 scopus 로고    scopus 로고
    • Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis
    • Hu Y, Coates AR, Mitchison DA (2003). Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis. Antimicrob Agents Chemother 47: 653-657.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 653-657
    • Hu, Y.1    Coates, A.R.2    Mitchison, D.A.3
  • 54
    • 0347604302 scopus 로고    scopus 로고
    • Bacteriophage treatment of a severe Escherichia coli respiratory infection in broiler chickens
    • Huff WE, Huff GR, Rath NC, Balog JM, Donoghue AM (2003). Bacteriophage treatment of a severe Escherichia coli respiratory infection in broiler chickens. Avian Dis 47: 1399-1405.
    • (2003) Avian Dis , vol.47 , pp. 1399-1405
    • Huff, W.E.1    Huff, G.R.2    Rath, N.C.3    Balog, J.M.4    Donoghue, A.M.5
  • 55
    • 33750297745 scopus 로고    scopus 로고
    • Conserved small non-coding RNAs that belong to the sigmaE regulon: Role in down-regulation of outer membrane proteins
    • Johansen J, Rasmussen AA, Overgaard M, Valentin-Hansen P (2006). Conserved small non-coding RNAs that belong to the sigmaE regulon: role in down-regulation of outer membrane proteins. J Mol Biol 364: 1-8.
    • (2006) J Mol Biol , vol.364 , pp. 1-8
    • Johansen, J.1    Rasmussen, A.A.2    Overgaard, M.3    Valentin-Hansen, P.4
  • 56
    • 33845959386 scopus 로고    scopus 로고
    • Transposon-aided capture (TRACA) of plasmids resident in the human gut mobile metagenome
    • Jones BV, Marchesi JR (2007). Transposon-aided capture (TRACA) of plasmids resident in the human gut mobile metagenome. Nat Methods 4: 55-61.
    • (2007) Nat Methods , vol.4 , pp. 55-61
    • Jones, B.V.1    Marchesi, J.R.2
  • 57
    • 4444366938 scopus 로고    scopus 로고
    • Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US - an update
    • Karchmer AW (2004). Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US - an update. Clin Infect Dis 39 (suppl 3): S142-S150.
    • (2004) Clin Infect Dis , vol.39 , Issue.SUPPL. 3
    • Karchmer, A.W.1
  • 58
    • 22544457611 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of misuse of antibiotic therapies in the community
    • Kardas P, Devine S, Golembesky A, Roberts C (2005). A systematic review and meta-analysis of misuse of antibiotic therapies in the community. Int J Antimicrob Agents 26: 106-113.
    • (2005) Int J Antimicrob Agents , vol.26 , pp. 106-113
    • Kardas, P.1    Devine, S.2    Golembesky, A.3    Roberts, C.4
  • 59
    • 33644761913 scopus 로고    scopus 로고
    • Daptomycin: First in a new class of antibiotics for complicated skin and soft-tissue infections
    • Kern WV (2006). Daptomycin: first in a new class of antibiotics for complicated skin and soft-tissue infections. Int J Clin Pract 60: 370-378.
    • (2006) Int J Clin Pract , vol.60 , pp. 370-378
    • Kern, W.V.1
  • 60
    • 33847263157 scopus 로고    scopus 로고
    • Screening and characterization of a novel fibrinolytic metalloprotease from a metagenomic library
    • Lee DG, Jeon JH, Jang MK, Kim NY, Lee JH, Lee JH et al. (2007). Screening and characterization of a novel fibrinolytic metalloprotease from a metagenomic library. Biotechnol Lett 29: 465-472.
    • (2007) Biotechnol Lett , vol.29 , pp. 465-472
    • Lee, D.G.1    Jeon, J.H.2    Jang, M.K.3    Kim, N.Y.4    Lee, J.H.5    Lee, J.H.6
  • 61
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis K (2007). Persister cells, dormancy and infectious disease. Nat Rev Microbiol 5: 48-56.
    • (2007) Nat Rev Microbiol , vol.5 , pp. 48-56
    • Lewis, K.1
  • 62
    • 33845711756 scopus 로고    scopus 로고
    • Prospects for plant-derived antibacterials
    • Lewis K, Ausubel FM (2006). Prospects for plant-derived antibacterials. Nat Biotechnol 24: 1504-1507.
    • (2006) Nat Biotechnol , vol.24 , pp. 1504-1507
    • Lewis, K.1    Ausubel, F.M.2
  • 63
    • 19544379870 scopus 로고    scopus 로고
    • Quinolone resistance in bacteria: Emphasis on plasmid-mediated mechanisms
    • Li XZ (2005). Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms. Int J Antimicrob Agents 25: 453-463.
    • (2005) Int J Antimicrob Agents , vol.25 , pp. 453-463
    • Li, X.Z.1
  • 64
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ (2001). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46: 3-26.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 66
    • 0035824437 scopus 로고    scopus 로고
    • Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase
    • Loeffler JM, Nelson D, Fischetti VA (2001). Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase. Science 294: 2170-2172.
    • (2001) Science , vol.294 , pp. 2170-2172
    • Loeffler, J.M.1    Nelson, D.2    Fischetti, V.A.3
  • 67
    • 0033919993 scopus 로고    scopus 로고
    • Peptide deformylase in Staphylococcus aureus: Resistance to inhibition is mediated by mutations in the formyltransferase gene
    • Margolis PS, Hackbarth CJ, Young DC, Wang W, Chen D, Yuan Z et al. (2000). Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene. Antimicrob Agents Chemother 44: 1825-1831.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1825-1831
    • Margolis, P.S.1    Hackbarth, C.J.2    Young, D.C.3    Wang, W.4    Chen, D.5    Yuan, Z.6
  • 68
    • 19944402594 scopus 로고    scopus 로고
    • Lysis-deficient bacteriophage therapy decreases endotoxin and inflammatory mediator release and improves survival in a murine peritonitis model
    • Matsuda T, Freeman TA, Hilbert DW, Duff M, Fuortes M, Stapleton PP et al. (2005). Lysis-deficient bacteriophage therapy decreases endotoxin and inflammatory mediator release and improves survival in a murine peritonitis model. Surgery 137: 639-646.
    • (2005) Surgery , vol.137 , pp. 639-646
    • Matsuda, T.1    Freeman, T.A.2    Hilbert, D.W.3    Duff, M.4    Fuortes, M.5    Stapleton, P.P.6
  • 69
    • 0035581737 scopus 로고    scopus 로고
    • Exploiting genomics to discover new antibiotics
    • McDevitt D, Rosenberg M (2001). Exploiting genomics to discover new antibiotics. Trends Microbiol 9: 611-617.
    • (2001) Trends Microbiol , vol.9 , pp. 611-617
    • McDevitt, D.1    Rosenberg, M.2
  • 71
    • 33644557421 scopus 로고    scopus 로고
    • When will the genomics investment pay off for antibacterial discovery?
    • Mills SD (2006). When will the genomics investment pay off for antibacterial discovery? Biochem Pharmacol 71: 1096-1102.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1096-1102
    • Mills, S.D.1
  • 72
    • 0031886212 scopus 로고    scopus 로고
    • How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis
    • Mitchison DA (1998). How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis. Int J Tuberc Lung Dis 2: 10-15.
    • (1998) Int J Tuberc Lung Dis , vol.2 , pp. 10-15
    • Mitchison, D.A.1
  • 73
    • 16344373224 scopus 로고    scopus 로고
    • The diagnosis and therapy of tuberculosis during the past 100 years
    • Mitchison DA (2005). The diagnosis and therapy of tuberculosis during the past 100 years. Am J Respir Crit Care Med 171: 699-706.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 699-706
    • Mitchison, D.A.1
  • 74
    • 33644504461 scopus 로고    scopus 로고
    • Antibacterial drug discovery - then, now and the genomics future
    • Monaghan RL, Barrett JF (2006). Antibacterial drug discovery - then, now and the genomics future. Biochem Pharmacol 71: 901-909.
    • (2006) Biochem Pharmacol , vol.71 , pp. 901-909
    • Monaghan, R.L.1    Barrett, J.F.2
  • 75
    • 0026347619 scopus 로고
    • Social, economic and operational research on tuberculosis: Recent studies and some priority questions
    • Murray CJ (1991). Social, economic and operational research on tuberculosis: recent studies and some priority questions. Bull Int Union Tuberc Lung Dis 66: 149-156.
    • (1991) Bull Int Union Tuberc Lung Dis , vol.66 , pp. 149-156
    • Murray, C.J.1
  • 76
    • 0036156073 scopus 로고    scopus 로고
    • Bacteriophage therapy of infectious diseases in aquaculture
    • Nakai T, Park SC (2002). Bacteriophage therapy of infectious diseases in aquaculture. Res Microbiol 153: 13-18.
    • (2002) Res Microbiol , vol.153 , pp. 13-18
    • Nakai, T.1    Park, S.C.2
  • 77
    • 0035957329 scopus 로고    scopus 로고
    • Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme
    • Nelson D, Loomis L, Fischetti VA (1997). Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme. Proc Natl Acad Sci USA 98: 4107-4112.
    • (1997) Proc Natl Acad Sci USA , vol.98 , pp. 4107-4112
    • Nelson, D.1    Loomis, L.2    Fischetti, V.A.3
  • 78
    • 33644924347 scopus 로고    scopus 로고
    • Principles of appropriate antibiotic use
    • Niederman MS (2005). Principles of appropriate antibiotic use. Int J Antimicrob Agents 26 (Suppl 3): S170-S175.
    • (2005) Int J Antimicrob Agents , vol.26 , Issue.SUPPL. 3
    • Niederman, M.S.1
  • 79
    • 12944302098 scopus 로고    scopus 로고
    • Lack of development of new antimicrobial drugs: A potential serious threat to public health
    • European Society of Clinical Microbiology and Infectious Diseases
    • Norrby SR, Nord CE, Finch R, European Society of Clinical Microbiology and Infectious Diseases (2005). Lack of development of new antimicrobial drugs: a potential serious threat to public health. Lancet Infect Dis 5: 115-119.
    • (2005) Lancet Infect Dis , vol.5 , pp. 115-119
    • Norrby, S.R.1    Nord, C.E.2    Finch, R.3
  • 80
    • 33846796432 scopus 로고    scopus 로고
    • Isolation and characterization of naphthalene-catabolic genes and plasmids from oil-contaminated soil by using two cultivation - independent approaches
    • Ono A, Miyazaki R, Sota M, Ohtsubo Y, Nagata Y, Tsuda M (2007). Isolation and characterization of naphthalene-catabolic genes and plasmids from oil-contaminated soil by using two cultivation - independent approaches. Appl Microbiol Biotechnol 74: 501-510.
    • (2007) Appl Microbiol Biotechnol , vol.74 , pp. 501-510
    • Ono, A.1    Miyazaki, R.2    Sota, M.3    Ohtsubo, Y.4    Nagata, Y.5    Tsuda, M.6
  • 81
    • 33747595241 scopus 로고    scopus 로고
    • The epidemiological profile of infections with multidrug-resistant Pseudomonas aeruginosa and Acinetobacter species
    • Paterson DL (2006). The epidemiological profile of infections with multidrug-resistant Pseudomonas aeruginosa and Acinetobacter species. Clin Infect Dis 43 (Suppl 2): S43-S48.
    • (2006) Clin Infect Dis , vol.43 , Issue.SUPPL. 2
    • Paterson, D.L.1
  • 82
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial drug discovery
    • Payne DJ, Gwynn MN, Holmes DJ, Pompliano DL (2007). Drugs for bad bugs: confronting the challenges of antibacterial drug discovery. Nat Rev Drug Discov 6: 29-40.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 83
    • 33644549679 scopus 로고    scopus 로고
    • The historical delivery of antibiotics from microbial natural products - can history repeat?
    • Pelaez F (2006). The historical delivery of antibiotics from microbial natural products - can history repeat? Biochem Pharmacol 71: 981-990.
    • (2006) Biochem Pharmacol , vol.71 , pp. 981-990
    • Pelaez, F.1
  • 84
    • 22144478311 scopus 로고    scopus 로고
    • Functional genomics of bacterial pathogens: From post-genomics to therapeutic targets
    • Polissi A, Soria MR (2005). Functional genomics of bacterial pathogens: from post-genomics to therapeutic targets. Mol Microbiol 57: 307-312.
    • (2005) Mol Microbiol , vol.57 , pp. 307-312
    • Polissi, A.1    Soria, M.R.2
  • 85
    • 15544384259 scopus 로고    scopus 로고
    • Antibacterial drug discovery: Is it all downhill from here?
    • Projan SJ, Shlaes DM (2004). Antibacterial drug discovery: is it all downhill from here? Clin Microbiol Infect 10: 18-22.
    • (2004) Clin Microbiol Infect , vol.10 , pp. 18-22
    • Projan, S.J.1    Shlaes, D.M.2
  • 86
    • 33644514658 scopus 로고    scopus 로고
    • Use of genomics to select antibacterial targets
    • Pucci MJ (2006). Use of genomics to select antibacterial targets. Biochem Pharmacol 71: 1066-1072.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1066-1072
    • Pucci, M.J.1
  • 87
    • 3042643505 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001-2002: The BSAC Bacteraemia Resistance Surveillance Programme
    • BSAC Extended Working Party on Bacteraemia Resistance Surveillance
    • Reynolds R, Potz N, Colman M, Williams A, Livermore D, MacGowan A, BSAC Extended Working Party on Bacteraemia Resistance Surveillance (2004). Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001-2002: the BSAC Bacteraemia Resistance Surveillance Programme. J Antimicrob Chemother 53: 1018-1032.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 1018-1032
    • Reynolds, R.1    Potz, N.2    Colman, M.3    Williams, A.4    Livermore, D.5    MacGowan, A.6
  • 88
    • 0019977506 scopus 로고
    • The history and background of Augmentin
    • Rolinson GN (1982). The history and background of Augmentin. S Afr Med J 28: 3A-4A.
    • (1982) S Afr Med J , vol.28
    • Rolinson, G.N.1
  • 89
    • 33845672122 scopus 로고    scopus 로고
    • The 50th anniversary of the discovery of 6-aminopenicillanic acid (6-APA)
    • Rolinson GN, Geddes AM (2007). The 50th anniversary of the discovery of 6-aminopenicillanic acid (6-APA). Int J Antimicrob Agents 29: 3-8.
    • (2007) Int J Antimicrob Agents , vol.29 , pp. 3-8
    • Rolinson, G.N.1    Geddes, A.M.2
  • 90
    • 18844481269 scopus 로고    scopus 로고
    • Cloning the soil metagenome: A strategy for accessing the genetic and functional diversity of uncultured microorganisms
    • Rondon MR, August PR, Bettermann AD, Brady SF, Grossman TH, Liles MR et al. (2000). Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms. Appl Environ Microbiol 66: 2541-2547.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 2541-2547
    • Rondon, M.R.1    August, P.R.2    Bettermann, A.D.3    Brady, S.F.4    Grossman, T.H.5    Liles, M.R.6
  • 92
    • 10044239624 scopus 로고    scopus 로고
    • A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa
    • Sakharkar KR, Sakharkar MK, Chow VT (2004). A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa. In Silico Biol 4: 355-360.
    • (2004) In Silico Biol , vol.4 , pp. 355-360
    • Sakharkar, K.R.1    Sakharkar, M.K.2    Chow, V.T.3
  • 93
    • 33644503872 scopus 로고    scopus 로고
    • Crystallizing new approaches for antimicrobial drug discovery
    • Schmid MB (2006a). Crystallizing new approaches for antimicrobial drug discovery. Biochem Pharmacol 71: 1048-1056.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1048-1056
    • Schmid, M.B.1
  • 94
    • 33645733997 scopus 로고    scopus 로고
    • Do targets limit antibiotic discovery?
    • Schmid MB (2006b). Do targets limit antibiotic discovery? Nat Biotechnol 24: 419-420.
    • (2006) Nat Biotechnol , vol.24 , pp. 419-420
    • Schmid, M.B.1
  • 95
    • 33747359398 scopus 로고    scopus 로고
    • Application of bacteriophages to control intestinal Escherichia coli O157:H7 levels in ruminants
    • Sheng H, Knecht HJ, Kudva IT, Hovde CJ (2006). Application of bacteriophages to control intestinal Escherichia coli O157:H7 levels in ruminants. Appl Environ Microbiol 72: 5359-5366.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 5359-5366
    • Sheng, H.1    Knecht, H.J.2    Kudva, I.T.3    Hovde, C.J.4
  • 96
    • 33845694144 scopus 로고    scopus 로고
    • Antibiotics au naturel
    • Sheridan C (2006). Antibiotics au naturel. Nat Biotechnol 24: 1494-1496.
    • (2006) Nat Biotechnol , vol.24 , pp. 1494-1496
    • Sheridan, C.1
  • 99
    • 0028420272 scopus 로고
    • Resistance to antibiotics mediated by target alterations
    • Spratt BG (1994). Resistance to antibiotics mediated by target alterations. Science 264: 388-393.
    • (1994) Science , vol.264 , pp. 388-393
    • Spratt, B.G.1
  • 101
    • 0347356354 scopus 로고    scopus 로고
    • Old dogma, new tricks - 21st century phage therapy
    • Thiel K (2004). Old dogma, new tricks - 21st century phage therapy. Nat Biotechnol 22: 31-36.
    • (2004) Nat Biotechnol , vol.22 , pp. 31-36
    • Thiel, K.1
  • 103
    • 0036523418 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of antibiotics: Challenges and opportunities
    • Walsh CT (2002). Combinatorial biosynthesis of antibiotics: challenges and opportunities. Chembiochem 3: 125-134.
    • (2002) Chembiochem , vol.3 , pp. 125-134
    • Walsh, C.T.1
  • 104
  • 105
    • 33744994317 scopus 로고    scopus 로고
    • Platensimycin is a selective FabF inhibitor with potent antibiotic properties
    • Wang J, Soisson SM, Young K, Shoop W, Kodal S, Galgoci A et al. (2006). Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441: 358-361.
    • (2006) Nature , vol.441 , pp. 358-361
    • Wang, J.1    Soisson, S.M.2    Young, K.3    Shoop, W.4    Kodal, S.5    Galgoci, A.6
  • 106
    • 14644440501 scopus 로고    scopus 로고
    • Bacteriophages - potential for application in wastewater treatment processes
    • Withey S, Cartmell E, Avery LM, Stephenson T (2005). Bacteriophages - potential for application in wastewater treatment processes. Sci Total Environ 339: 1-18.
    • (2005) Sci Total Environ , vol.339 , pp. 1-18
    • Withey, S.1    Cartmell, E.2    Avery, L.M.3    Stephenson, T.4
  • 108
    • 33744460747 scopus 로고    scopus 로고
    • Targeting antibacterial agents by using drug-carrying filamentous bacteriophages
    • Yacoby I, Shamis M, Bar H, Shabat D, Benhar I (2006). Targeting antibacterial agents by using drug-carrying filamentous bacteriophages. Antimicrob Agents Chemother 50: 2087-2097.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2087-2097
    • Yacoby, I.1    Shamis, M.2    Bar, H.3    Shabat, D.4    Benhar, I.5
  • 109
    • 0032838896 scopus 로고    scopus 로고
    • Directly observed therapy, short-course: The best way to prevent multidrug-resistant tuberculosis
    • Yew WW (1999). Directly observed therapy, short-course: the best way to prevent multidrug-resistant tuberculosis. Chemotherapy 45 (Suppl 2): 26-33.
    • (1999) Chemotherapy , vol.45 , Issue.SUPPL. 2 , pp. 26-33
    • Yew, W.W.1
  • 110
    • 33644519967 scopus 로고    scopus 로고
    • The evolution of peptide deformylase as a target: Contribution of biochemistry, genetics and genomics
    • Yuan Z, White RJ (2006). The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics. Biochem Pharmacol 71: 1042-1047.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1042-1047
    • Yuan, Z.1    White, R.J.2
  • 112
    • 4143124486 scopus 로고    scopus 로고
    • Macrolides and ketolides: Azithromycin, clarithromycin, telithromycin
    • Zuckerman JM (2004). Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. Infect Dis Clin North Am 18: 621-649.
    • (2004) Infect Dis Clin North Am , vol.18 , pp. 621-649
    • Zuckerman, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.