Phospho-MurNAc-pentapeptide translocase (MraY) as a target for antibacterial agents and antibacterial proteins

Infectious Disorders - Drug Targets

Volumn 6, Issue 2, 2006, Pages 85-106

  Bugg, Timothy D H ^a   Lloyd, Adrian J ^a,b   Roper, David I ^b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Antibacterial agents; High throughout screening; MraY; Peptidoglycan biosynthesis

Indexed keywords

AMFOMYCIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CAPURAMYCIN DERIVATIVE; CARRIER PROTEIN; LIPOSIDOMYCIN DERIVATIVE; METAL ION; MURAYMYCIN DERIVATIVE; MUREIDOMYCIN A; MUREIDOMYCIN B; MUREIDOMYCIN C; MUREIDOMYCIN D; NAPSAMYCIN A; NAPSAMYCIN B; NAPSAMYCIN C; NATURAL PRODUCT; NUCLEOSIDE DERIVATIVE; PACIDAMYCIN 1; PACIDAMYCIN 2; PACIDAMYCIN 3; PACIDAMYCIN 4; PACIDAMYCIN 5; PACIDAMYCIN 6; PACIDAMYCIN 7; PEPTIDOGLYCAN; PHOSPHO N ACETYL MURAMIC ACID PENTAPEPTIDE TRANSLOCASE; PHOSPHOLIPID; TUNICAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIOPHAGE PHI X 174; BIOSYNTHESIS; CATALYSIS; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE IDENTIFICATION; GRAM NEGATIVE INFECTION; HIGH THROUGHPUT SCREENING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACOPHORE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; SOLUBILIZATION; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; MODELS, BIOLOGICAL; PEPTIDOGLYCAN; TRANSFERASES;

EID: 33745090237     PISSN: 18715265     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152606784112128     Document Type: Article

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