메뉴 건너뛰기




Volumn 28, Issue , 2007, Pages 39-51

Comparing genetically engineered mouse mammary cancer models with human breast cancer by expression profiling

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; MYC PROTEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 36549078221     PISSN: 08886008     EISSN: None     Source Type: Journal    
DOI: 10.3233/bd-2007-28105     Document Type: Review
Times cited : (13)

References (106)
  • 1
    • 36549050410 scopus 로고    scopus 로고
    • Cancer Facts & Figures 2007. In. Atlanta: American Cancer Society; 2007.
    • Cancer Facts & Figures 2007. In. Atlanta: American Cancer Society; 2007.
  • 2
    • 27244434470 scopus 로고    scopus 로고
    • Effect of screening and adjuvant therapy on mortality from breast cancer
    • D.A. Berry, K.A. Cronin, S.K. Plevritis et al., Effect of screening and adjuvant therapy on mortality from breast cancer, N Engl J Med 353(17) (2005), 1784-1792.
    • (2005) N Engl J Med , vol.353 , Issue.17 , pp. 1784-1792
    • Berry, D.A.1    Cronin, K.A.2    Plevritis, S.K.3
  • 4
    • 33646439130 scopus 로고    scopus 로고
    • Prognosis and management of patients with node-negative invasive breast carcinoma that is 1 cm or smaller in size (stage 1; T1a,bN0M0): A review ofthe literature
    • E.O. Hanrahan, V. Valero, A.M. Gonzalez-Angulo and G.N. Hortobagyi, Prognosis and management of patients with node-negative invasive breast carcinoma that is 1 cm or smaller in size (stage 1; T1a,bN0M0): A review ofthe literature, J Clin Oncol 24(13) (2006), 2113-2122.
    • (2006) J Clin Oncol , vol.24 , Issue.13 , pp. 2113-2122
    • Hanrahan, E.O.1    Valero, V.2    Gonzalez-Angulo, A.M.3    Hortobagyi, G.N.4
  • 5
    • 13044304179 scopus 로고    scopus 로고
    • Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
    • C.M. Perou, S.S. Jeffrey, M. van de Rijn et al., Distinctive gene expression patterns in human mammary epithelial cells and breast cancers, Proc Natl Acad Sci USA 96(16) (1999), 9212-9217.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.16 , pp. 9212-9217
    • Perou, C.M.1    Jeffrey, S.S.2    van de Rijn, M.3
  • 6
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • C.M. Perou, T. Sorlie, M.B. Eisen et al., Molecular portraits of human breast tumours, Nature 406(6797) (2000), 747-752.
    • (2000) Nature , vol.406 , Issue.6797 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 7
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • T. Sorlie, C.M. Perou, R. Tibshirani et al., Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications, Proc Natl Acad Sci USA 98(19) (2001), 10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.19 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 8
    • 0034696279 scopus 로고    scopus 로고
    • The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting
    • R.D. Cardiff, M.R. Anver, B.A. Gusterson et al., The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting, Oncogene 19(8) (2000), 968-988.
    • (2000) Oncogene , vol.19 , Issue.8 , pp. 968-988
    • Cardiff, R.D.1    Anver, M.R.2    Gusterson, B.A.3
  • 9
    • 2442564320 scopus 로고    scopus 로고
    • Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses
    • J. Blancato, B. Singh, A. Liu, D.J. Liao and R.B. Dickson, Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses, Br J Cancer 90(8) (2004), 1612-1619.
    • (2004) Br J Cancer , vol.90 , Issue.8 , pp. 1612-1619
    • Blancato, J.1    Singh, B.2    Liu, A.3    Liao, D.J.4    Dickson, R.B.5
  • 10
    • 0034538306 scopus 로고    scopus 로고
    • C-myc amplification in breast cancer: A meta-analysis of its occurrence and prognostic relevance
    • S.L. Deming, S.J. Nass, R.B. Dickson and B.J. Trock, C-myc amplification in breast cancer: A meta-analysis of its occurrence and prognostic relevance, Br J Cancer 83(12) (2000), 1688-1695.
    • (2000) Br J Cancer , vol.83 , Issue.12 , pp. 1688-1695
    • Deming, S.L.1    Nass, S.J.2    Dickson, R.B.3    Trock, B.J.4
  • 11
    • 0038024096 scopus 로고    scopus 로고
    • C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer
    • C.M. Schlotter, U. Vogt, U. Bosse, B. Mersch and K. Wassmann, C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer, Breast Cancer Res 5(2) (2003), R30-R36.
    • (2003) Breast Cancer Res , vol.5 , Issue.2
    • Schlotter, C.M.1    Vogt, U.2    Bosse, U.3    Mersch, B.4    Wassmann, K.5
  • 12
    • 0035719960 scopus 로고    scopus 로고
    • Wnt signaling in breast cancer: Have we come full circle?
    • A.M. Brown, Wnt signaling in breast cancer: Have we come full circle? Breast Cancer Res 3(6) (2001), 351-355.
    • (2001) Breast Cancer Res , vol.3 , Issue.6 , pp. 351-355
    • Brown, A.M.1
  • 13
    • 0034636153 scopus 로고    scopus 로고
    • Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • S.Y. Lin, W. Xia, J.C. Wang et al., Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression, Proc Natl Acad Sci USA 97(8) (2000), 4262-4266.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.8 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3
  • 15
    • 3342952083 scopus 로고    scopus 로고
    • Notch in mammary gland development and breast cancer
    • K. Politi, N. Feirt and J. Kitajewski, Notch in mammary gland development and breast cancer, Semin Cancer Biol 14(5) (2004), 341-347.
    • (2004) Semin Cancer Biol , vol.14 , Issue.5 , pp. 341-347
    • Politi, K.1    Feirt, N.2    Kitajewski, J.3
  • 16
    • 0036734148 scopus 로고    scopus 로고
    • Activation of Notch-1 signaling maintains the neoplastic phenotype in human Rastransformed cells
    • S. Weijzen, P. Rizzo, M. Braid et al., Activation of Notch-1 signaling maintains the neoplastic phenotype in human Rastransformed cells, Nat Med 8(9) (2002), 979-986.
    • (2002) Nat Med , vol.8 , Issue.9 , pp. 979-986
    • Weijzen, S.1    Rizzo, P.2    Braid, M.3
  • 17
    • 24944506696 scopus 로고    scopus 로고
    • High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
    • M. Reedijk, S. Odorcic, L. Chang et al., High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival, Cancer Res 65(18) (2005), 8530-8537.
    • (2005) Cancer Res , vol.65 , Issue.18 , pp. 8530-8537
    • Reedijk, M.1    Odorcic, S.2    Chang, L.3
  • 18
    • 0028129951 scopus 로고
    • The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas
    • J. Bartkova, J. Lukas, M. Strauss and J. Bartek, The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas, Int J Cancer 58(4) (1994), 568-573.
    • (1994) Int J Cancer , vol.58 , Issue.4 , pp. 568-573
    • Bartkova, J.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 19
    • 0027280084 scopus 로고
    • Expression and amplification of cyclin genes in human breast cancer
    • M.F. Buckley, K.J. Sweeney, J.A. Hamilton et al., Expression and amplification of cyclin genes in human breast cancer, Oncogene 8(8) (1993), 2127-2133.
    • (1993) Oncogene , vol.8 , Issue.8 , pp. 2127-2133
    • Buckley, M.F.1    Sweeney, K.J.2    Hamilton, J.A.3
  • 20
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immuno-histochemical staining
    • C. Gillett, V. Fantl, R. Smith et al., Amplification and overexpression of cyclin D1 in breast cancer detected by immuno-histochemical staining, Cancer Res 54(7) (1994), 1812-1817.
    • (1994) Cancer Res , vol.54 , Issue.7 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3
  • 21
    • 0023857935 scopus 로고
    • Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading
    • M.S. Berger, G.W. Locher, S. Saurer et al., Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading, Cancer Res 48(5) (1988), 1238-1243.
    • (1988) Cancer Res , vol.48 , Issue.5 , pp. 1238-1243
    • Berger, M.S.1    Locher, G.W.2    Saurer, S.3
  • 22
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • D.J. Slamon, G.M. Clark, S.G. Wong, W.J. Levin, A. Ullrich and W.L. McGuire, Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene, Science 235(4785) (1987), 177-182.
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 23
    • 0029002907 scopus 로고
    • Aberrant function of the Ras signal transduction pathway in human breast cancer
    • G.J. Clark and C.J. Der, Aberrant function of the Ras signal transduction pathway in human breast cancer, Breast Cancer Res Treat 35(1) (1995), 133-144.
    • (1995) Breast Cancer Res Treat , vol.35 , Issue.1 , pp. 133-144
    • Clark, G.J.1    Der, C.J.2
  • 25
    • 0028843102 scopus 로고
    • Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium
    • D.F. Easton, D. Ford and D.T. Bishop, Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium, Am J Hum Genet 56(1) (1995), 265-271.
    • (1995) Am J Hum Genet , vol.56 , Issue.1 , pp. 265-271
    • Easton, D.F.1    Ford, D.2    Bishop, D.T.3
  • 26
    • 17344365851 scopus 로고    scopus 로고
    • Genetic heterogeneity and penetrance analysis ofthe BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium
    • D. Ford, D.F. Easton, M. Stratton et al., Genetic heterogeneity and penetrance analysis ofthe BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium, Am J Hum Genet 62(3) (1998), 676-689.
    • (1998) Am J Hum Genet , vol.62 , Issue.3 , pp. 676-689
    • Ford, D.1    Easton, D.F.2    Stratton, M.3
  • 27
    • 0032486752 scopus 로고    scopus 로고
    • Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations
    • S.R. Lakhani, J. Jacquemier, J.P. Sloane et al., Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations, J Natl Cancer Inst 90(15) (1998), 1138-1145.
    • (1998) J Natl Cancer Inst , vol.90 , Issue.15 , pp. 1138-1145
    • Lakhani, S.R.1    Jacquemier, J.2    Sloane, J.P.3
  • 28
    • 0029901708 scopus 로고    scopus 로고
    • High frequency of aberrant p 16(INK4A) expression in human breast cancer
    • J. Geradts and P.A. Wilson, High frequency of aberrant p 16(INK4A) expression in human breast cancer, Am J Pathol 149(1) (1996), 15-20.
    • (1996) Am J Pathol , vol.149 , Issue.1 , pp. 15-20
    • Geradts, J.1    Wilson, P.A.2
  • 29
    • 0001510491 scopus 로고    scopus 로고
    • C.J. Sherr and F. McCormick, The RB and p53 pathways in cancer, Cancer Cell 2(2) (2002), 103-112.
    • C.J. Sherr and F. McCormick, The RB and p53 pathways in cancer, Cancer Cell 2(2) (2002), 103-112.
  • 30
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • R.A. Weinberg, The retinoblastoma protein and cell cycle control, Cell 81(3) (1995), 323-330.
    • (1995) Cell , vol.81 , Issue.3 , pp. 323-330
    • Weinberg, R.A.1
  • 31
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • M.S. Greenblatt, W.P. Bennett, M. Hollstein and C.C. Harris, Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis, Cancer Res 54(18) (1994), 4855-4878.
    • (1994) Cancer Res , vol.54 , Issue.18 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 32
    • 0024387728 scopus 로고
    • Mutations in the p53 gene occur in diverse human tumour types
    • J.M. Nigro, S.J. Baker, A.C. Preisinger et al., Mutations in the p53 gene occur in diverse human tumour types, Nature 342(6250) (1989), 705-708.
    • (1989) Nature , vol.342 , Issue.6250 , pp. 705-708
    • Nigro, J.M.1    Baker, S.J.2    Preisinger, A.C.3
  • 33
    • 0032814777 scopus 로고    scopus 로고
    • Somatic mutations in the p53 gene and prognosis in breast cancer: A meta-analysis
    • P.D. Pharoah, N.E. Day and C. Caldas, Somatic mutations in the p53 gene and prognosis in breast cancer: A meta-analysis, Br J Cancer 80 12) (1999), 1968-1973.
    • (1999) Br J Cancer , vol.80 , Issue.12 , pp. 1968-1973
    • Pharoah, P.D.1    Day, N.E.2    Caldas, C.3
  • 35
    • 0034458540 scopus 로고    scopus 로고
    • Genetically engineered mouse models of mammary intraepithelial neoplasia
    • R.D. Cardiff, D. Moghanaki and R.A. Jensen, Genetically engineered mouse models of mammary intraepithelial neoplasia, J Mammary Gland Biol Neoplasia 5(4) (2000), 421-437.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , Issue.4 , pp. 421-437
    • Cardiff, R.D.1    Moghanaki, D.2    Jensen, R.A.3
  • 36
    • 0032547564 scopus 로고    scopus 로고
    • Polychemotherapy for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group
    • Polychemotherapy for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group, Lancet 352(9132) (1998), 930-942.
    • (1998) Lancet , vol.352 , Issue.9132 , pp. 930-942
  • 37
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • L.J. van 't Veer, H. Dai, M.J. van de Vijver et al., Gene expression profiling predicts clinical outcome of breast cancer, Nature 415(6871) (2002), 530-536.
    • (2002) Nature , vol.415 , Issue.6871 , pp. 530-536
    • van 't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3
  • 38
    • 12444340932 scopus 로고    scopus 로고
    • Adjuvant therapy for breast cancer: Practical lessons from the early breast cancer trialists' collaborative group
    • C.A. Hudis and C.T. Dang, Adjuvant therapy for breast cancer: Practical lessons from the early breast cancer trialists' collaborative group, Breast Dis 21 (2004), 3-13.
    • (2004) Breast Dis , vol.21 , pp. 3-13
    • Hudis, C.A.1    Dang, C.T.2
  • 39
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • T. Sorlie, R. Tibshirani, J. Parker et al., Repeated observation of breast tumor subtypes in independent gene expression data sets, Proc Natl Acad Sci USA 100(14) (2003), 8418-8423.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 40
    • 33745834662 scopus 로고    scopus 로고
    • Distinct molecular mechanisms underlying clinically relevant subtypes ofbreast cancer: Gene expression analyses across three different platforms
    • T. Sorlie, Y. Wang, C. Xiao et al., Distinct molecular mechanisms underlying clinically relevant subtypes ofbreast cancer: Gene expression analyses across three different platforms, BMC Genomics 7 (2006), 127.
    • (2006) BMC Genomics , vol.7 , pp. 127
    • Sorlie, T.1    Wang, Y.2    Xiao, C.3
  • 41
    • 27144488136 scopus 로고    scopus 로고
    • Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer
    • B. Weigelt, Z. Hu, X. He et al., Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer, Cancer Res 65(20) (2005), 9155-9158.
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9155-9158
    • Weigelt, B.1    Hu, Z.2    He, X.3
  • 42
    • 33847126689 scopus 로고    scopus 로고
    • Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
    • M.L. Asselin-Labat, K.D. Sutherland, H. Barker et al., Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation, Nat Cell Biol 9(2) (2007), 201-209.
    • (2007) Nat Cell Biol , vol.9 , Issue.2 , pp. 201-209
    • Asselin-Labat, M.L.1    Sutherland, K.D.2    Barker, H.3
  • 43
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • H. Kouros-Mehr, E.M. Slorach, M.D. Sternlicht and Z. Werb, GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland, Cell 127(5) (2006), 1041-1055.
    • (2006) Cell , vol.127 , Issue.5 , pp. 1041-1055
    • Kouros-Mehr, H.1    Slorach, E.M.2    Sternlicht, M.D.3    Werb, Z.4
  • 44
    • 33846704749 scopus 로고    scopus 로고
    • Nestin is expressed in the basal/ myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors
    • H. Li, P. Cherukuri, N. Li et al., Nestin is expressed in the basal/ myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors, Cancer Res 67(2) (2007), 501-510.
    • (2007) Cancer Res , vol.67 , Issue.2 , pp. 501-510
    • Li, H.1    Cherukuri, P.2    Li, N.3
  • 45
    • 23844549918 scopus 로고    scopus 로고
    • Breast cancer molecular subtypes respond differently to preoperative chemotherapy
    • R. Rouzier, C.M. Perou, W.F. Symmans et al., Breast cancer molecular subtypes respond differently to preoperative chemotherapy, Clin Cancer Res 11(16) (2005), 5678-5685.
    • (2005) Clin Cancer Res , vol.11 , Issue.16 , pp. 5678-5685
    • Rouzier, R.1    Perou, C.M.2    Symmans, W.F.3
  • 46
    • 33847063053 scopus 로고    scopus 로고
    • The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
    • L.A. Carey, E.C. Dees, L. Sawyer et al., The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes, Clin Cancer Res 13(8) (2007), 2329-2334.
    • (2007) Clin Cancer Res , vol.13 , Issue.8 , pp. 2329-2334
    • Carey, L.A.1    Dees, E.C.2    Sawyer, L.3
  • 47
    • 0037137519 scopus 로고    scopus 로고
    • M.J. van de Vijver, L.J. He YD, van't Veer et al., A gene-expression signature as a predictor of survival in breast cancer, N Engl J Med 347(25) (2002), 1999-2009.
    • M.J. van de Vijver, L.J. He YD, van't Veer et al., A gene-expression signature as a predictor of survival in breast cancer, N Engl J Med 347(25) (2002), 1999-2009.
  • 48
    • 33748693297 scopus 로고    scopus 로고
    • Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
    • M. Buyse, S. Loi, L. van't Veer et al., Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer, J Natl Cancer Inst 98(17) (2006), 1183-1192.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.17 , pp. 1183-1192
    • Buyse, M.1    Loi, S.2    van't Veer, L.3
  • 49
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • H.F. Dvorak, Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing, N Engl J Med 315(26) (1986), 1650-1659.
    • (1986) N Engl J Med , vol.315 , Issue.26 , pp. 1650-1659
    • Dvorak, H.F.1
  • 50
    • 19344363035 scopus 로고    scopus 로고
    • Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
    • H.Y. Chang, J.B. Sneddon, A.A. Alizadeh et al., Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds, PLoS Biol 2(2) (2004), E7.
    • (2004) PLoS Biol , vol.2 , Issue.2
    • Chang, H.Y.1    Sneddon, J.B.2    Alizadeh, A.A.3
  • 51
    • 20144386127 scopus 로고    scopus 로고
    • Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    • H.Y. Chang, D.S. Nuyten, J.B. Sneddon et al., Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival, Proc Natl Acad Sci USA 102 10) (2005), 3738-3743.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.10 , pp. 3738-3743
    • Chang, H.Y.1    Nuyten, D.S.2    Sneddon, J.B.3
  • 53
    • 34250687198 scopus 로고    scopus 로고
    • Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PLEN tumor suppressor pathway activity
    • L.H. Saal, P. Johansson, K. Holm et al., Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PLEN tumor suppressor pathway activity, Proc Natl Acad Sci USA 104(18) (2007), 7564-7569.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.18 , pp. 7564-7569
    • Saal, L.H.1    Johansson, P.2    Holm, K.3
  • 54
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • S. Paik, S. Shak, G. Tang et al., A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer, N Engl J Med 351(27) (2004), 2817-2826.
    • (2004) N Engl J Med , vol.351 , Issue.27 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3
  • 55
    • 2942578063 scopus 로고    scopus 로고
    • A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    • X.J. Ma, Z. Wang, P.D. Ryan et al., A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen, Cancer Cell 5(6) (2004), 607-616.
    • (2004) Cancer Cell , vol.5 , Issue.6 , pp. 607-616
    • Ma, X.J.1    Wang, Z.2    Ryan, P.D.3
  • 56
    • 33746910265 scopus 로고    scopus 로고
    • Concordance among gene-expression-based predictors for breast cancer
    • C. Fan, D.S. Oh, L. Wessels et al., Concordance among gene-expression-based predictors for breast cancer, N Engl J Med 355(6) (2006), 560-569.
    • (2006) N Engl J Med , vol.355 , Issue.6 , pp. 560-569
    • Fan, C.1    Oh, D.S.2    Wessels, L.3
  • 57
    • 33645825183 scopus 로고    scopus 로고
    • Thousands ofsamples are needed to generate a robust gene list for predicting outcome in cancer
    • L. Ein-Dor, O. Zukand E. Domany, Thousands ofsamples are needed to generate a robust gene list for predicting outcome in cancer, Proc Natl Acad Sci USA 103(15) (2006), 5923-5928.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.15 , pp. 5923-5928
    • Ein-Dor, L.1    Zukand, O.2    Domany, E.3
  • 58
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from turnorigenic breast-cancer cells
    • R. Liu, X. Wang, G.Y. Chen et al., The prognostic role of a gene signature from turnorigenic breast-cancer cells, N Engl J Med 356(3) (2007), 217-226.
    • (2007) N Engl J Med , vol.356 , Issue.3 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3
  • 59
    • 0037076342 scopus 로고    scopus 로고
    • Initiating oncogenic event determines gene-expression patterns of human breast cancer models
    • K.V. Desai, N. Xiao, W. Wang et al., Initiating oncogenic event determines gene-expression patterns of human breast cancer models, Proc Natl Acad Sci USA 99(10) (2002), 6967-6972.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.10 , pp. 6967-6972
    • Desai, K.V.1    Xiao, N.2    Wang, W.3
  • 60
    • 0141569009 scopus 로고    scopus 로고
    • Myc-driven murine prostate cancer shares molecular features with human prostate tumors
    • K. Ellwood-Yen, T.G. Graeber, J. Wongvipat et al., Myc-driven murine prostate cancer shares molecular features with human prostate tumors, Cancer Cell 4(3) (2003), 223-238.
    • (2003) Cancer Cell , vol.4 , Issue.3 , pp. 223-238
    • Ellwood-Yen, K.1    Graeber, T.G.2    Wongvipat, J.3
  • 61
    • 0025863346 scopus 로고
    • Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
    • M. van Lohuizen, S. Verbeek, B. Scheijen, E. Wientjens, H. van der Gulden and A. Berns, Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging, Cell 65(5) (1991), 737-752.
    • (1991) Cell , vol.65 , Issue.5 , pp. 737-752
    • van Lohuizen, M.1    Verbeek, S.2    Scheijen, B.3    Wientjens, E.4    van der Gulden, H.5    Berns, A.6
  • 62
    • 0031194107 scopus 로고    scopus 로고
    • A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer
    • W.W. He, P.J. Sciavolino, J. Wing et al., A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer, Genomics 43(1) (1997), 69-77.
    • (1997) Genomics , vol.43 , Issue.1 , pp. 69-77
    • He, W.W.1    Sciavolino, P.J.2    Wing, J.3
  • 63
    • 33745220780 scopus 로고    scopus 로고
    • Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
    • P. Kaposi-Novak, J.S. Lee, L. Gomez-Quiroz, C. Coulouarn, V.M. Factor and S.S. Thorgeirsson, Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype, J Clin Invest 116(6) (2006), 1582-1595.
    • (2006) J Clin Invest , vol.116 , Issue.6 , pp. 1582-1595
    • Kaposi-Novak, P.1    Lee, J.S.2    Gomez-Quiroz, L.3    Coulouarn, C.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 64
    • 0038724909 scopus 로고    scopus 로고
    • c-Met: Structure, functions and potential for therapeutic inhibition
    • P.C. Ma, G. Maulik, J. Christensen and R. Salgia, c-Met: Structure, functions and potential for therapeutic inhibition, Cancer Metastasis Rev 22(4) (2003), 309-325.
    • (2003) Cancer Metastasis Rev , vol.22 , Issue.4 , pp. 309-325
    • Ma, P.C.1    Maulik, G.2    Christensen, J.3    Salgia, R.4
  • 65
    • 11244258643 scopus 로고    scopus 로고
    • An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
    • A. Sweet-Cordero, S. Mukherjee, A. Subramanian et al., An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis, Nat Genet 37(1) (2005), 48-55.
    • (2005) Nat Genet , vol.37 , Issue.1 , pp. 48-55
    • Sweet-Cordero, A.1    Mukherjee, S.2    Subramanian, A.3
  • 66
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • J.I. Herschkowitz, K. Simin, V.J. Weigman et al., Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors, Genome Biol 8(5) (2007), R76.
    • (2007) Genome Biol , vol.8 , Issue.5
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3
  • 67
    • 9144269759 scopus 로고    scopus 로고
    • Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    • Y. Li, B. Welm, K. Podsypanina et al., Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells, Proc Natl Acad Sci USA 100 26) (2003), 15853-15858.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.26 , pp. 15853-15858
    • Li, Y.1    Welm, B.2    Podsypanina, K.3
  • 68
    • 33845941448 scopus 로고    scopus 로고
    • The Win signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis
    • C. Lindvall, N.C. Evans, C.R. Zylstra, Y. Li, C.M. Alexander and B.O. Williams, The Win signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis, J Biol Chem 281(46) (2006), 35081-35087.
    • (2006) J Biol Chem , vol.281 , Issue.46 , pp. 35081-35087
    • Lindvall, C.1    Evans, N.C.2    Zylstra, C.R.3    Li, Y.4    Alexander, C.M.5    Williams, B.O.6
  • 69
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haernatopoietic stem cells
    • T. Reya, A.W. Duncan, L. Ailles et al., A role for Wnt signalling in self-renewal of haernatopoietic stem cells, Nature 423(6938) (2003), 409-414.
    • (2003) Nature , vol.423 , Issue.6938 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3
  • 70
    • 36549051693 scopus 로고    scopus 로고
    • Identification of an Integrated SV40 T/t-antigen Cancer Signature in Aggressive Human Carcinomas With Poor Prognosis
    • Submitted
    • K.K. Deeb, A.M. Michalowska, C.Y. Yoon et al., Identification of an Integrated SV40 T/t-antigen Cancer Signature in Aggressive Human Carcinomas With Poor Prognosis. Submitted.
    • Deeb, K.K.1    Michalowska, A.M.2    Yoon, C.Y.3
  • 71
    • 27944459717 scopus 로고    scopus 로고
    • SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
    • D. Ahuja, M.T. Saenz-Robles and J.M. Pipas, SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation, Oncogene 24(52) (2005), 7729-7745.
    • (2005) Oncogene , vol.24 , Issue.52 , pp. 7729-7745
    • Ahuja, D.1    Saenz-Robles, M.T.2    Pipas, J.M.3
  • 72
    • 0036494442 scopus 로고    scopus 로고
    • Clinical validation of candidate genes associated with prostate cancer progression in the CWR22 model system using tissue microarrays
    • S. Mousses, L. Bubendorf, U. Wagner et al., Clinical validation of candidate genes associated with prostate cancer progression in the CWR22 model system using tissue microarrays, Cancer Res 62(5) (2002), 1256-1260.
    • (2002) Cancer Res , vol.62 , Issue.5 , pp. 1256-1260
    • Mousses, S.1    Bubendorf, L.2    Wagner, U.3
  • 73
    • 13644266312 scopus 로고    scopus 로고
    • Caveolin-1 in oncogenic transformation, cancer, and metastasis
    • T.M. Williams and M.P. Lisanti, Caveolin-1 in oncogenic transformation, cancer, and metastasis, Am J Physiol Cell Physiol 288(3) (2005), C494-C506.
    • (2005) Am J Physiol Cell Physiol , vol.288 , Issue.3
    • Williams, T.M.1    Lisanti, M.P.2
  • 74
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • G.V. Glinsky, O. Berezovska and A.B. Glinskii, Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer, J Clin Invest 115(6) (2005), 1503-1521.
    • (2005) J Clin Invest , vol.115 , Issue.6 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 75
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • L.A. Boyer, K. Plath, J. Zeitlinger et al., Polycomb complexes repress developmental regulators in murine embryonic stem cells, Nature 441(7091) (2006), 349-353.
    • (2006) Nature , vol.441 , Issue.7091 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3
  • 76
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • J. Lessard and G. Sauvageau, Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells, Nature 423(6937) (2003), 255-260.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 77
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • A.V. Molofsky, R. Pardal, T. Iwashita, I.K. Park, M.F. Clarke and S.J. Morrison, Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation, Nature 425(6961) (2003), 962-967.
    • (2003) Nature , vol.425 , Issue.6961 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 78
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • I.K. Park, D. Qian, M. Kiel et al., Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells, Nature 423 6937) (2003), 302-305.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3
  • 79
    • 0038137601 scopus 로고    scopus 로고
    • Gene expression profiles ofhuman breast cancer progression
    • X.J. Ma, R. Salunga, J.T. Tuggle et al., Gene expression profiles ofhuman breast cancer progression, Proc Natl Acad Sci USA 100 10) (2003), 5974-5979.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.10 , pp. 5974-5979
    • Ma, X.J.1    Salunga, R.2    Tuggle, J.T.3
  • 80
    • 8444223465 scopus 로고    scopus 로고
    • Molecular mechanisms of breast cancer progression: Lessons from mouse mammary cancer models and gene expression profiling
    • Y. Ye, T.H. Qiu, C. Kavanaugh and J.E. Green, Molecular mechanisms of breast cancer progression: Lessons from mouse mammary cancer models and gene expression profiling, Breast Dis 19 (2004), 69-82.
    • (2004) Breast Dis , vol.19 , pp. 69-82
    • Ye, Y.1    Qiu, T.H.2    Kavanaugh, C.3    Green, J.E.4
  • 81
    • 54949090320 scopus 로고    scopus 로고
    • A mouse stromal response to tumor invasion predicts prostate and breast cancer patient survival
    • M. Bacac, P. Provero, N. Mayran, J.C. Stehle, C. Fusco and I. Stamenkovic, A mouse stromal response to tumor invasion predicts prostate and breast cancer patient survival, PLoS ONE 1 (2006), e32.
    • (2006) PLoS ONE , vol.1
    • Bacac, M.1    Provero, P.2    Mayran, N.3    Stehle, J.C.4    Fusco, C.5    Stamenkovic, I.6
  • 82
    • 0031823908 scopus 로고    scopus 로고
    • Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression
    • T. Lifsted, T. Le Voyer, M. Williams et al., Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression, Int J Cancer 77(4) (1998), 640-644.
    • (1998) Int J Cancer , vol.77 , Issue.4 , pp. 640-644
    • Lifsted, T.1    Le Voyer, T.2    Williams, M.3
  • 83
    • 4344688268 scopus 로고    scopus 로고
    • Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: Correlation to human disease
    • T.H. Qiu, G.V. Chandramouli, K.W. Hunter, N.W. Alkharouf, J.E. Green and E.T. Liu, Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: Correlation to human disease, Cancer Res 64(17) (2004), 5973-5981.
    • (2004) Cancer Res , vol.64 , Issue.17 , pp. 5973-5981
    • Qiu, T.H.1    Chandramouli, G.V.2    Hunter, K.W.3    Alkharouf, N.W.4    Green, J.E.5    Liu, E.T.6
  • 84
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • S. Ramaswamy, K.N. Ross, E.S. Lander and T.R. Golub, A molecular signature of metastasis in primary solid tumors, Nat Genet 33 1) (2003), 49-54.
    • (2003) Nat Genet , vol.33 , Issue.1 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 85
    • 0035893391 scopus 로고    scopus 로고
    • Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1
    • K.W. Hunter, K.W. Broman, T.L. Voyer et al., Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1, Cancer Res 61(24) (2001), 8866-8872.
    • (2001) Cancer Res , vol.61 , Issue.24 , pp. 8866-8872
    • Hunter, K.W.1    Broman, K.W.2    Voyer, T.L.3
  • 86
    • 25844511053 scopus 로고    scopus 로고
    • Sipal is a candidate for underlying the metastasis efficiency modifier locus Mtes1
    • Y.G. Park, X. Zhao, F. Lesueur et al., Sipal is a candidate for underlying the metastasis efficiency modifier locus Mtes1, Nat Genet 37(10) (2005), 1055-1062.
    • (2005) Nat Genet , vol.37 , Issue.10 , pp. 1055-1062
    • Park, Y.G.1    Zhao, X.2    Lesueur, F.3
  • 87
    • 33746506286 scopus 로고    scopus 로고
    • Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer
    • N.P. Crawford, A. Ziogas, D.J. Peel, J. Hess, H. Anton-Culver and K.W. Hunter, Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer, Breast Cancer Res 8(2) (2006), R16.
    • (2006) Breast Cancer Res , vol.8 , Issue.2
    • Crawford, N.P.1    Ziogas, A.2    Peel, D.J.3    Hess, J.4    Anton-Culver, H.5    Hunter, K.W.6
  • 88
    • 22844445705 scopus 로고    scopus 로고
    • Temporal dissection of p53 function in vitro and in vivo
    • M.A. Christophorou, D. Martin-Zanca, L. Soucek et al., Temporal dissection of p53 function in vitro and in vivo, Nat Genet 37(7) (2005), 718-726.
    • (2005) Nat Genet , vol.37 , Issue.7 , pp. 718-726
    • Christophorou, M.A.1    Martin-Zanca, D.2    Soucek, L.3
  • 89
    • 0029818753 scopus 로고    scopus 로고
    • Time-sensitive reversal of hyperplasia, in transgenic mice expressing SV40 T antigen
    • D. Ewald, M. Li, S. Efrat et al., Time-sensitive reversal of hyperplasia, in transgenic mice expressing SV40 T antigen, Science 273(5280) (1996), 1384-1386.
    • (1996) Science , vol.273 , Issue.5280 , pp. 1384-1386
    • Ewald, D.1    Li, M.2    Efrat, S.3
  • 90
    • 0036187113 scopus 로고    scopus 로고
    • A novel doxycycline- inducible system for the transgenic analysis of mammary gland biology
    • E.J. Gunther, G.K. Belka, G.B. Wertheim et al., A novel doxycycline- inducible system for the transgenic analysis of mammary gland biology, Faseb J 16(3) (2002), 283-292.
    • (2002) Faseb J , vol.16 , Issue.3 , pp. 283-292
    • Gunther, E.J.1    Belka, G.K.2    Wertheim, G.B.3
  • 91
    • 0029586870 scopus 로고
    • Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system
    • L. Hennighausen, R.J. Wall, U. Tillmann, M. Li and P.A. Furth, Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system, J Cell Biochem 59(4) (1995), 463-472.
    • (1995) J Cell Biochem , vol.59 , Issue.4 , pp. 463-472
    • Hennighausen, L.1    Wall, R.J.2    Tillmann, U.3    Li, M.4    Furth, P.A.5
  • 92
    • 19044370434 scopus 로고    scopus 로고
    • Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
    • S.E. Moody, C.J. Sarkisian, K.T. Hahn et al., Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis, Cancer Cell 2(6) (2002), 451-461.
    • (2002) Cancer Cell , vol.2 , Issue.6 , pp. 451-461
    • Moody, S.E.1    Sarkisian, C.J.2    Hahn, K.T.3
  • 93
    • 33846899456 scopus 로고    scopus 로고
    • Restoration of p53 function leads to tumour regression in vivo
    • A. Ventura, D.G. Kirsch, M.E. McLaughlin et al., Restoration of p53 function leads to tumour regression in vivo, Nature 445 7128) (2007), 661-665.
    • (2007) Nature , vol.445 , Issue.7128 , pp. 661-665
    • Ventura, A.1    Kirsch, D.G.2    McLaughlin, M.E.3
  • 94
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • W. Xue, L. Zender C. Miething et al., Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas, Nature 445(7128) (2007), 656-660.
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3
  • 95
    • 0035126052 scopus 로고    scopus 로고
    • c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • C.M. D'Cruz, E.J. Gunther, R.B. Boxer et al., c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations, Nat Med 7(2) (2001), 235-239.
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 235-239
    • D'Cruz, C.M.1    Gunther, E.J.2    Boxer, R.B.3
  • 96
    • 0037442760 scopus 로고    scopus 로고
    • Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
    • E.J. Gunther, S.E. Moody, G.K. Belka et al., Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis, Genes Dev 17(4) (2003), 488-501.
    • (2003) Genes Dev , vol.17 , Issue.4 , pp. 488-501
    • Gunther, E.J.1    Moody, S.E.2    Belka, G.K.3
  • 97
    • 10944258521 scopus 로고    scopus 로고
    • Lack of sustained regression ofc-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation
    • R.B. Boxer, J.W. Jang, L. Sintasath and L.A. Chodosh, Lack of sustained regression ofc-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation, Cancer Cell 6(6) (2004), 577-586.
    • (2004) Cancer Cell , vol.6 , Issue.6 , pp. 577-586
    • Boxer, R.B.1    Jang, J.W.2    Sintasath, L.3    Chodosh, L.A.4
  • 98
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • S.E. Moody, D. Perez, T.C. Pan et al., The transcriptional repressor Snail promotes mammary tumor recurrence, Cancer Cell 8(3) (2005), 197-209.
    • (2005) Cancer Cell , vol.8 , Issue.3 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3
  • 99
    • 33750379861 scopus 로고    scopus 로고
    • Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary turnorigenesis
    • J.W. Jang, R.B. Boxer and L.A. Chodosh, Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary turnorigenesis, Mol Cell Biol 26(21) (2006), 8109-8121.
    • (2006) Mol Cell Biol , vol.26 , Issue.21 , pp. 8109-8121
    • Jang, J.W.1    Boxer, R.B.2    Chodosh, L.A.3
  • 100
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • A.H. Bild, G. Yao, J.T. Chang et al., Oncogenic pathway signatures in human cancers as a guide to targeted therapies, Nature 439 7074) (2006), 353-357.
    • (2006) Nature , vol.439 , Issue.7074 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3
  • 101
    • 33947702646 scopus 로고    scopus 로고
    • Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin-Cyclophosphamide Regimen
    • P. Bertheau, E. Turpin, D.S. Rickman et al., Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin-Cyclophosphamide Regimen, PLoS Med 4(3) (2007), e90.
    • (2007) PLoS Med , vol.4 , Issue.3
    • Bertheau, P.1    Turpin, E.2    Rickman, D.S.3
  • 102
    • 33750727368 scopus 로고    scopus 로고
    • Genomic signatures to guide the use of chemotherapeutics
    • A. Potti, H.K. Dressman, A. Bild et al., Genomic signatures to guide the use of chemotherapeutics, Nat Med 12(11) (2006), 1294-1300.
    • (2006) Nat Med , vol.12 , Issue.11 , pp. 1294-1300
    • Potti, A.1    Dressman, H.K.2    Bild, A.3
  • 103
    • 33749433916 scopus 로고    scopus 로고
    • Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
    • H. Hieronymus, J. Lamb, K.N. Ross et al., Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators, Cancer Cell 10(4) (2006), 321-330.
    • (2006) Cancer Cell , vol.10 , Issue.4 , pp. 321-330
    • Hieronymus, H.1    Lamb, J.2    Ross, K.N.3
  • 104
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • J. Lamb, F.D. Crawford, D. Peck et al., The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease, Science 313(5795) (2006), 1929-1935.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1929-1935
    • Lamb, J.1    Crawford, F.D.2    Peck, D.3
  • 105
    • 33749443714 scopus 로고    scopus 로고
    • Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance
    • G. Wei, D. Twomey, J. Lamb et al., Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance, Cancer Cell 10(4) (2006), 331-342.
    • (2006) Cancer Cell , vol.10 , Issue.4 , pp. 331-342
    • Wei, G.1    Twomey, D.2    Lamb, J.3
  • 106
    • 34247478069 scopus 로고    scopus 로고
    • Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma
    • K. Stegmaier J.S. Wong, K.N. Ross et al., Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma, PLoSMed 4(4) (2007), e122.
    • (2007) PLoSMed , vol.4 , Issue.4
    • Stegmaier, K.1    Wong, J.S.2    Ross, K.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.