Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 18, 2007, Pages 7564-7569

  Saal, Lao H ^a,b   Johansson, Peter ^b   Holm, Karolina ^b   Gruvberger Saal, Sofia K ^a,b   She, Qing Bai ^c   Maurer, Matthew ^a   Koujak, Susan ^a   Ferrando, Adolfo A ^a   Malmström, Per ^b   Memeo, Lorenzo ^a,e   Isola, Jorma ^d   Bendahl, Pär Ola ^b   Rosen, Neal ^c   Hibshoosh, Hanina ^a   Ringnér, Markus ^b   Borg, Åke ^b   Parsons, Ramon ^a  

^a Columbia University ^*  (United States)

^b LUND UNIVERSITY   (Sweden)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d UNIVERSITY OF TAMPERE   (Finland)

^e Mediterranean Institute of Oncology   (Italy)

Author keywords

Breast cancer; Metastasis; Microarray; Stathmin

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STATHMIN; TAMOXIFEN; PTEN PROTEIN, HUMAN; TUMOR MARKER; UNCLASSIFIED DRUG;

ADJUVANT THERAPY; ARTICLE; BLADDER CARCINOMA; BREAST CARCINOMA; CANCER RELAPSE; CANCER SURVIVAL; CELL PROLIFERATION; DISEASE FREE SURVIVAL; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; METASTASIS; OUTCOMES RESEARCH; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOLID TUMOR; TUMOR SUPPRESSOR GENE; CARCINOMA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; SURVIVAL RATE; TREATMENT OUTCOME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CARCINOMA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROGNOSIS; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 34250687198     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702507104     Document Type: Article

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